Taosheng Chen

7.7k citations

154 papers · 5.0k indexed · h-index 39

Pharmacology top 0.1%
- Pharmacogenetics and Drug Metabolism 59
Oncology top 2%
- Drug Transport and Resistance Mechanisms 26
Endocrinology, Diabetes and Metabolism top 1%
- Hormonal Regulation and Hypertension 36
Molecular Biology top 5%
- Ubiquitin and proteasome pathways 15
- Protein Degradation and Inhibitors 14
Physiology top 2%
Genetics
- Estrogen and related hormone effects 30
Computational Theory and Mathematics
- Computational Drug Discovery Methods 7
Hematology
- Multiple Myeloma Research and Treatments 7

Co-authors: Wenwei Lin Sergio C. Chai William L. Farrar Lihua Wang Yueming Wang Peter Oladimeji Su Sien OngJing Wu
Cited by: Pharmacology Oncology Endocrinology, Diabetes and Metabolism
Journals: Science (1 paper)Cell (1 paper)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States China United Kingdom

In The Last Decade

Taosheng Chen

149 papers receiving 4.9k citations

Peers

Countries citing papers authored by Taosheng Chen

Since Specialization

Citations

This map shows the geographic impact of Taosheng Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Taosheng Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Taosheng Chen more than expected).

Fields of papers citing papers by Taosheng Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Taosheng Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Taosheng Chen. The network helps show where Taosheng Chen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Taosheng Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Taosheng Chen Line = papers co-authored together Taosheng Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Decoding the selective chemical modulation of CYP3A4 Nature Communications ·Jingheng Wang,Stanley Nithianantham,Sergio C. Chai,Kwan‐Young Jung,Lei Yang,Han Wee Ong,Yong Li,Yifan Zhang,Darcie J. Miller,Taosheng Chen	2025	1
2	Direct targeting and regulation of RNA polymerase II by cell signaling kinases Science ·Preeti Dabas,Meritxell B. Cutrona,Wojciech Rosikiewicz,Ryan P. Kempen,Patrick Fernandes Rodrigues,John J. Bowling,Mollie S. Prater,Walter H. Lang,Adithi Danda,Yuan Zhi,Beisi Xu,Shondra M. Pruett‐Miller,Gang Wu,Taosheng Chen,Aseem Z. Ansari	2025	0
3	Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR Nature Communications ·Efren Garcia-Maldonado,Andrew D. Huber,Sergio C. Chai,Stanley Nithianantham,Yongtao Li,Jing Wu,Shyaron Poudel,Darcie J. Miller,J. Seetharaman,Taosheng Chen	2024	13
4	Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand Structure ·Andrew D. Huber,Shyaron Poudel,Yongtao Li,Wenwei Lin,Jing Wu,Darcie J. Miller,Taosheng Chen	2023	9
5	Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors ACS Medicinal Chemistry Letters ·Caroline R. Buchholz,Molly Sneddon,Joseph E. McPherson,Sourav Das,Clifford T. Gee,Michael J. Grillo,Sergio C. Chai,Richard Lee,Taosheng Chen,Daniel A. Harki,Anang A. Shelat,William C. K. Pomerantz	2023	2
6	Small molecule SJ572946 activates BAK to initiate apoptosis iScience ·G. Sekar,Geetika Singh,Xingping Qin,Cristina D. Guibao,Brittany Schwam,Zintis Inde,Christy R. Grace,Weixing Zhang,P.J. Slavish,Wenwei Lin,Taosheng Chen,Richard Lee,Zoran Ranković,Kristopher A. Sarosiek,Tudor Moldoveanu	2022	9
7	Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader ACS Medicinal Chemistry Letters ·Anand Divakaran,Cole R. Scholtz,Huda Zahid,Wenwei Lin,Elizabeth C. Griffith,Richard Lee,Taosheng Chen,Daniel A. Harki,William C. K. Pomerantz	2022	8
8	Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation Clinical Cancer Research ·Elizabeth R. Hayden,Mingqing Chen,Kyle Z. Pasquariello,Alice A. Gibson,James J. Petti,Shichen Shen,Jun Qu,Su Sien Ong,Taosheng Chen,Yan Jin,Muhammad Erfan Uddin,Kevin M. Huang,Aviv Paz,Alex Sparreboom,Shuiying Hu,Jason A. Sprowl	2021	27
9	BRAF inhibition protects against hearing loss in mice Science Advances ·Matthew A. Ingersoll,Emma A. Malloy,Lauryn E. Caster,Eva Holland,Zhenhang Xu,Marisa Zallocchi,Duane Currier,Huizhan Liu,David Z. Z. He,Jaeki Min,Taosheng Chen,Jian Zuo,Tal Teitz	2020	40
10	Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen eLife ·Hao Zhang,Yang Zhang,Xinyue Zhou,Shaela Wright,Judith Hyle,Lianzhong Zhao,Jie An,Xujie Zhao,Ying Shao,Beisi Xu,Hyeong-Min Lee,Taosheng Chen,Yang Zhou,Xiang Chen,Rui Lu,Chunliang Li	2020	27
11	Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5 Journal of Medicinal Chemistry ·William C. Wright,Jude Chenge,Jingheng Wang,Hazel M. Girvan,Lei Yang,Sergio C. Chai,Andrew D. Huber,Jing Wu,Peter Oladimeji,Andrew W. Munro,Taosheng Chen	2020	34
12	MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation Cell Death Discovery ·Jane E. Craig,Joseph N. Miller,Raju R. Rayavarapu,Zhenya Hong,Gamze B. Bulut,Wei Zhuang,Sadie Miki Sakurada,Jamshid Temirov,Jonathan Low,Taosheng Chen,Shondra M. Pruett‐Miller,Lily Huang,Malia B. Potts	2020	6
13	Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8 ⁺ T cell responses Science Translational Medicine ·Anthony E. Zamora,Jeremy Chase Crawford,E. Kaitlynn Allen,Xi-zhi J. Guo,Jesse Bakke,Robert Carter,Hossam A. Abdelsamed,Ardiana Moustaki,Yongjin Li,Ti‐Cheng Chang,Walid Awad,Mari Dallas,Charles G. Mullighan,James R. Downing,Terrence L. Geiger,Taosheng Chen,Douglas R. Green,Ben Youngblood,Jinghui Zhang,Paul G. Thomas	2019	59
14	High-Throughput Screening Identifies 1,4,5-Substituted 1,2,3-Triazole Analogs as Potent and Specific Antagonists of Pregnane X Receptor Assay and Drug Development Technologies ·Wenwei Lin,Asli N. Goktug,Jing Wu,Duane Currier,Taosheng Chen	2017	12
15	An unexpected protein interaction promotes drug resistance in leukemia Nature Communications ·Aaron Pitre,Yubin Ge,Wenwei Lin,Yao Wang,Yu Fukuda,Jamshid Temirov,Aaron H. Phillips,Jennifer L. Peters,Yiping Fan,Jing Ma,Amanda Nourse,Chandrima Sinha,Hai Lin,Richard W. Kriwacki,James R. Downing,Tanja A. Grüber,Victoria E. Centonze,Anjaparavanda P. Naren,Taosheng Chen,John D. Schuetz	2017	20
16	Multikinase Inhibitors Induce Cutaneous Toxicity through OAT6-Mediated Uptake and MAP3K7-Driven Cell Death Cancer Research ·Eric I. Zimmerman,Alice A. Gibson,Shuiying Hu,Aksana Vasilyeva,Shelley Orwick,Guoqing Du,Gerard P. Mascara,Su Sien Ong,Taosheng Chen,Peter Vogel,Hiroto Inaba,Michael L. Maitland,Alex Sparreboom,Sharyn D. Baker	2016	38
17	High Throughput Screening Identified a Substituted Imidazole as a Novel RANK Pathway-Selective Osteoclastogenesis Inhibitor Assay and Drug Development Technologies ·Taosheng Chen,A C Knapp,Wu Yang,Jinwen Huang,Jean S. Lynch,John K. Dickson,R. Michael Lawrence,Jean H.M. Feyen,Michele Agler	2006	10
18	Cell-Based Assay Strategy for Identification of Motif-Specific RANK Signaling Pathway Inhibitors Assay and Drug Development Technologies ·Taosheng Chen,Xu Feng	2006	6
19	Analysis of cellular events using CellCard™ System in cell-based high-content multiplexed assays Expert Review of Molecular Diagnostics ·Taosheng Chen,George P. Hansen,Oren Beske,Kristin Yates,Yingjie Zhu,Monique Anthony,Michele Agler,Martyn Banks	2005	3
20	Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells. PubMed ·Taosheng Chen,Lihua Wang,William L. Farrar	2000	214

About Taosheng Chen

Taosheng Chen is a scholar working on Pharmacology, Endocrinology, Diabetes and Metabolism and Oncology, having authored 154 papers that have together received 5.0k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (59 papers), Hormonal Regulation and Hypertension (36 papers), Estrogen and related hormone effects (30 papers), Drug Transport and Resistance Mechanisms (26 papers), Ubiquitin and proteasome pathways (15 papers), Protein Degradation and Inhibitors (14 papers), Computational Drug Discovery Methods (7 papers) and Multiple Myeloma Research and Treatments (7 papers). The work is most often cited by research in Pharmacology (1.4k citations), Oncology (1.3k citations) and Endocrinology, Diabetes and Metabolism (803 citations). Taosheng Chen has collaborated with scholars based in United States, China and United Kingdom. Frequent co-authors include Wenwei Lin, Sergio C. Chai, William L. Farrar, Lihua Wang, Yueming Wang, Peter Oladimeji, Su Sien Ong, Jing Wu, William C. Wright and Jing Wu. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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