Weidong Le

24.5k total citations · 3 hit papers
289 papers, 17.2k citations indexed

About

Weidong Le is a scholar working on Neurology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Weidong Le has authored 289 papers receiving a total of 17.2k indexed citations (citations by other indexed papers that have themselves been cited), including 129 papers in Neurology, 111 papers in Molecular Biology and 102 papers in Cellular and Molecular Neuroscience. Recurrent topics in Weidong Le's work include Parkinson's Disease Mechanisms and Treatments (106 papers), Nuclear Receptors and Signaling (62 papers) and Alzheimer's disease research and treatments (45 papers). Weidong Le is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (106 papers), Nuclear Receptors and Signaling (62 papers) and Alzheimer's disease research and treatments (45 papers). Weidong Le collaborates with scholars based in China, United States and United Kingdom. Weidong Le's co-authors include Yu Tang, Joseph Jankovic, Sheng Chen, Song Li, Stanley H. Appel, Wenjie Xie, Wenjie Xie, Tianhong Pan, Joseph Jankovic and Dehua Yang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Weidong Le

281 papers receiving 16.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

2015 1.7k citations Weidong Le et al. profile →
Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

1998 618 citations Odila Saucedo‐Cárdenas, Weidong Le et al. profile →
Autophagy in neurodegenerative diseases: pathogenesis and therapy

2017 313 citations Huaibin Cai, Weidong Le et al. profile →

Peers

Countries citing papers authored by Weidong Le

Since Specialization

Citations

This map shows the geographic impact of Weidong Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Weidong Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Weidong Le more than expected).

Fields of papers citing papers by Weidong Le

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Weidong Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Weidong Le. The network helps show where Weidong Le may publish in the future.

Co-authorship network of co-authors of Weidong Le

This figure shows the co-authorship network connecting the top 25 collaborators of Weidong Le. A scholar is included among the top collaborators of Weidong Le based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Weidong Le. Weidong Le is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Biological Effects of Dietary Restriction on Alzheimer's Disease: Experimental and Clinical Investigations 2025 ·CNS Neuroscience & Therapeutics ·(unknown), Jun Zhang, (unknown), Cong Liu, Yaping Shao, Weidong Le	1
2	Astrocytic Mettl14 depletion enhances cognitive function by attenuating astrogliosis via the DUSP1/MAPK pathway in APP/PS1 mice: targeting neuroinflammation in Alzheimer’s disease 2025 ·Molecular Psychiatry ·Yan Teng, (unknown), S. M. He, Yi Jin, (unknown), Qin Tang, Xingmin Chen, Wei Fan, Yanzhuo Liu, Haisong Jiang, Yang Xiang, (unknown), (unknown), Weidong Le, Mingyue Zheng, Lu Yang	0
3	HSF-1 Regulates Autophagy to Govern Motor Function and Facilitate Toxic Protein Clearance in a C. elegans Model of Amyotrophic Lateral Sclerosis 2025 ·Neuroscience Bulletin ·Hui Xu, Yaping Shao, Jun Zhang, (unknown), Guowang Xu, (unknown), Yi Liang, Weidong Le	0
4	Single‐Molecule Insight Into α‐Synuclein Fibril Structure and Mechanics Modulated by Chemical Compounds 2025 ·Advanced Science ·(unknown), (unknown), Shenqing Zhang, (unknown), Wencheng Xia, Youqi Tao, (unknown), Yanan Li, Weidong Le, Wenyan Kang, Dan Li, Bo Sun, Cong Liu	1
5	In situ amplification of α-synuclein amyloid fibril reveals a distinct polymorph related to Parkinson’s disease and dementia with Lewy body 2025 ·Cell Reports ·(unknown), Qinyue Zhao, (unknown), (unknown), Youqi Tao, (unknown), Feng Gao, Yong Shen, (unknown), (unknown), Cong Liu, Weidong Le, Dan Li	0
6	Microglia in the crosstalk between peripheral and central nervous systems in Parkinson’s disease 2025 ·Translational Neurodegeneration ·Tianbai Li, (unknown), (unknown), Huaibin Cai, Weidong Le	0
7	Fecal microbiota from patients with Parkinson's disease intensifies inflammation and neurodegeneration in A53T mice 2024 ·CNS Neuroscience & Therapeutics ·(unknown), Yaping Shao, (unknown), (unknown), Panpan Wang, Lulu Tian, (unknown), Song Li, Murad Al‐Nusaif, Cong Liu, Weidong Le	9
8	NLRP3 Inflammasome-Mediated Neuroinflammation and Related Mitochondrial Impairment in Parkinson’s Disease 2023 ·Neuroscience Bulletin ·Qiu-Qin Han, Weidong Le	54
9	A metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting 2023 ·Signal Transduction and Targeted Therapy ·Yaping Shao, Zhenfa Fu, Yanfeng Wang, Zhaofei Yang, (unknown), Song Li, Cheng Cheng, Min Wei, Zheyi Liu, Guowang Xu, Weidong Le	10
10	Pyrylium-Based Derivatization for Rapid Labeling and Enhanced Detection of Cholesterol in Mass Spectrometry Imaging 2022 ·Journal of the American Society for Mass Spectrometry ·Shuai Huang, Xinxin Liu, Dan Liu, Xiaozhe Zhang, Lihua Zhang, Weidong Le, Yukui Zhang	2
11	Altered Biological Rhythm and Alzheimer's Disease: A Bidirectional Relationship 2021 ·Current Alzheimer Research ·Manli Wang, Hang Yu, Song Li, Yang Xiang, Weidong Le	3
12	Exercise and Parkinson's disease 2019 ·International review of neurobiology ·Xiaojiao Xu, Zhenfa Fu, Weidong Le	105
13	Potential biomarkers of Parkinson's disease revealed by plasma metabolic profiling 2018 ·Journal of Chromatography B ·(unknown), Cui Wang, Nan Zhao, Wenxue Li, Zhaofei Yang, Xinxin Liu, Weidong Le, Xiaozhe Zhang	81
14	Autophagy dysregulation in amyotrophic lateral sclerosis 2015 ·Journal of the Neurological Sciences ·(unknown), Weidong Le, Xingcai Zhang	2
15	Early diagnosis and therapy of Parkinson’s disease: can disease progression be curbed? 2012 ·Journal of Neural Transmission ·(unknown), (unknown), Sheng Chen, Joseph Jankovic, Weidong Le	17
16	Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson’s Disease 2011 ·Neurosignals ·Yun‐Cheng Wu, Xinqun Li, Julie Zhu, Wenjie Xie, Weidong Le, Zhen Fan, Joseph Jankovic, Tianhong Pan	405
17	Interferon-α-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression 2005 ·Journal of Hepatology ·Wei Cai, Vladimir I. Khaoustov, Qing Xie, Tianhong Pan, Weidong Le, Boris Yoffe	75
18	The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease 2005 ·Progress in Neurobiology ·Joseph Jankovic, Sheng Chen, Weidong Le	269
19	Activated Microglia Initiate Motor Neuron Injury by a Nitric Oxide and Glutamate-Mediated Mechanism 2004 ·Journal of Neuropathology & Experimental Neurology ·Weihua Zhao, Wenjie Xie, Weidong Le, David R. Beers, Yi He, Jenny S. Henkel, Ericka P. Simpson, Albert Yen, Qin Xiao, Stanley H. Appel	136
20	Selective Agenesis of Mesencephalic Dopaminergic Neurons in Nurr1-Deficient Mice 1999 ·Experimental Neurology ·Weidong Le, Orla M. Conneely, Linglong Zou, Yi He, Odila Saucedo‐Cárdenas, Joseph Jankovic, Dennis R. Mosier, Stanley H. Appel	121

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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