Andrew Pike

2.8k citations

26 papers · 1.8k indexed · 1 hit paper · h-index 19

Impact in

Organic Chemistry top 2%
- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Synthesis and biological activity
- Synthesis and Catalytic Reactions
- Synthesis and Biological Evaluation
Nephrology top 5%
- Gout, Hyperuricemia, Uric Acid

Papers in

Biological Psychiatry 2
Cellular and Molecular Neuroscience 11
- Neuroscience and Neuropharmacology Research 11

Co-authors: Yun Zhang Serge I. Gorelsky Shathaverdhan Potavathri Brenton DeBoef Charles D. Jones Keith A. Wafford Caroline Benn Vivek Dua
Journals: Journal of Medicinal Chemistry (10 papers)Bioorganic & Medicinal Chemistry Letters (8 papers)Journal of Pharmacology and Experimental Therapeutics (1 paper)Biopharmaceutics & Drug Disposition (1 paper)Journal of the American Chemical Society (1 paper)
Partner nations: United Kingdom United States Denmark

In The Last Decade

Andrew Pike

26 papers receiving 1.8k citations

Hit Papers

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Physiology of Hyperuricemia and Urate-Lowering Treatments 2018 · 222 citations

Peers

Countries citing papers authored by Andrew Pike

Since Specialization

Citations

This map shows the geographic impact of Andrew Pike's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew Pike with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew Pike more than expected).

Fields of papers citing papers by Andrew Pike

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew Pike. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew Pike. The network helps show where Andrew Pike may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Andrew Pike, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Andrew Pike Line = papers co-authored together Andrew Pike links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pyridones in drug discovery: Recent advances Bioorganic & Medicinal Chemistry Letters ·Yun Zhang, Andrew Pike	2021	97
2	Physiology of Hyperuricemia and Urate-Lowering Treatments Frontiers in Medicine ·Caroline Benn, Vivek Dua, Rachel Gurrell, Peter T. Loudon, Andrew Pike, Richard Storer, Ciara Vangjeli Hit paper breakdown →	2018	222
3	Regioselective Oxidative Arylation of Indoles Bearing N-Alkyl Protecting Groups: Dual C−H Functionalization via a Concerted Metalation−Deprotonation Mechanism Journal of the American Chemical Society ·Shathaverdhan Potavathri, Eloisa Morales, Serge I. Gorelsky, Andrew Pike, R. J. Lee, Brenton DeBoef	2010	251
4	Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1 ACS Medicinal Chemistry Letters ·Wesley Blackaby, Richard T. Lewis, И.П. Ли, Charlotte Johannsen, Simon Goodacre, Leslie J. Street, Angus M. MacLeod, Andrew Pike, Maria Isabel Fernandes Torquato de Sá, Steve Thomas, Terry Brown, Alison J. Smith, Gopalan V. Pillai, Sarah Almond, Martin R. Guscott, H. Donald Burns, Waisi Eng, Christine Ryan, Jacquelynn J. Cook, Terence G. Hamill	2010	14
5	Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors Bioorganic & Medicinal Chemistry Letters ·И.П. Ли, Wesley Blackaby, Charlotte Johannsen, Simon Goodacre, Andrew Pike, Steve Thomas, Terry Brown, Alison J. Smith, Gopalan V. Pillai, Leslie J. Street, Richard T. Lewis	2009	7
6	The discovery of fused pyrrole carboxylic acids as novel, potent d-amino acid oxidase (DAO) inhibitors Bioorganic & Medicinal Chemistry Letters ·Tim Sparey, Pravien Abeywickrema, Sarah Almond, Nicholas J. Brandon, Noel Byrne, Damian Smedley, Pete H. Hutson, Marlene A. Jacobson, Brian V. Jones, Sanjeev Munshi, Danette Pascarella, Andrew Pike, G. Sridhar Prasad, Nancy A. Sachs, Jean Claude Lavanchy, Vinod Sardana, Shankar Venkatraman, Mary Beth Young	2008	63
7	Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands Biopharmaceutics & Drug Disposition ·Andrew Pike, Susan M. Cook, Alan P. Watt, Paul Scott‐Stevens, Thomas W. Rosahl, Ruth M. McKernan, Ehapo CS, Y. Nacoshi, Christopher R. Moyes, Bindi Sohal, John Atack	2007	2
8	The role of GABA_Aβ2 subunit‐containing receptors in mediating the anticonvulsant and sedative effects of loreclezole European Journal of Neuroscience ·Daniel Arya Deva, Martin R. Guscott, David J. Hallett, Thomas W. Rosahl, Andrew Pike, Zhenglong Duan, Keith A. Wafford, David S. Reynolds	2006	24
9	A Pyridazine Series of α2/α3 Subtype Selective GABA_A Agonists for the Treatment of Anxiety Journal of Medicinal Chemistry ·Richard T. Lewis, Wesley Blackaby, Timothy J. Blackburn, Charlotte Johannsen, Andrew Pike, Kelly Dever, David J. Hallett, Susan M. Cook, O. Yu. Panckuk, George Marshall, David S. Reynolds, Nafis Tanzeem Hossain, Alison J. Smith, Bindi Sohal, Joanna L. Stanley, Spencer J. Tye, Keith A. Wafford, John Atack	2006	25
10	Imidazo[1,2-a]pyrimidines as functionally selective GABAA ligands Bioorganic & Medicinal Chemistry Letters ·Wesley Blackaby, John Atack, Frances A. Bromidge, José L. Castro, Simon Goodacre, David J. Hallett, Richard T. Lewis, George Marshall, Andrew Pike, Alison J. Smith, Leslie J. Street, Lakshika Kollure, Keith A. Wafford	2006	36
11	TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2 H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates Journal of Pharmacology and Experimental Therapeutics ·John Atack, Keith A. Wafford, Spencer J. Tye, Susan M. Cook, Bindi Sohal, Andrew Pike, Cyrille Sur, David G. Melillo, Linda J. Bristow, Sujan Dahal, Ian Ragan, Julie Kerby, Yuta Nishibe, Robert W. Carling, José L. Castro, Paul J. Whiting, Gerard R. Dawson, Ruth M. McKernan	2005	156
12	Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as α2/α3 subtype selective GABAA agonists for the treatment of anxiety Bioorganic & Medicinal Chemistry Letters ·Simon Goodacre, David J. Hallett, Robert W. Carling, José L. Castro, David S. Reynolds, Andrew Pike, Keith A. Wafford, Robert Newman, John Atack, Leslie J. Street	2005	19
13	Tricyclic pyridones as functionally selective human GABAAα2/3 receptor-ion channel ligands Bioorganic & Medicinal Chemistry Letters ·James Crawforth, John Atack, Susan M. Cook, Karl R. Gibson, Alan Nadin, Andrew P. Owens, Andrew Pike, Michael Rowley, Alison J. Smith, Bindi Sohal, Francine Sternfeld, Keith A. Wafford, Leslie J. Street	2004	11
14	Synthesis and Biological Evaluation of 3-Heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and Analogues as Subtype-Selective Inverse Agonists for the GABA_Aα5 Benzodiazepine Binding Site Journal of Medicinal Chemistry ·Leslie J. Street, Francine Sternfeld, Richard A. Jelley, Austin J. Reeve, Robert W. Carling, Kevin W. Moore, Ruth M. McKernan, Bindi Sohal, Susan M. Cook, Andrew Pike, Gerard R. Dawson, Frances A. Bromidge, Keith A. Wafford, Guy R. Seabrook, Sally A. Thompson, George Marshall, G. Jörgensen, José L. Castro, John Atack, Angus M. MacLeod	2004	61
15	1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D₄Receptor with Excellent Selectivity over Ion Channels Journal of Medicinal Chemistry ·Robert W. Carling, Kevin W. Moore, Christopher R. Moyes, Elizabeth A. Jones, 鈴木邦和, Frances Emms, R. Marwood, Shil Patel, Smita S. Patel, Alan E. Fletcher, Margaret S. Beer, Bindi Sohal, Andrew Pike, Paul D. Leeson	1999	50
16	Discovery and structure-activity relationship of a series of 1-carba-1-dethiacephems exhibiting activity against methicillin-resistant Staphylococcus aureus Journal of Medicinal Chemistry ·Robert J. Ternansky, Susan E. Draheim, Andrew Pike, A. Laketich, Sarah J. West, Christopher L. Jordan, Changbu Wu, David A. Preston, William E. Alborn	1993	27
17	Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase Journal of Medicinal Chemistry ·Charles D. Jones, James E. Audia, 芸儿, Loretta A. McQuaid, Blake Lee Neubauer, Andrew Pike, Khalid W. Al-Quliti, Nancy B. Stamm, Richard E. Toomey, Kenneth S. Hirsch	1993	77
18	Structure-activity relationship within a series of pyrazolidinone antibacterial agents. 2. Effect of side-chain modification on in vitro activity and pharmacokinetic parameters Journal of Medicinal Chemistry ·Robert J. Ternansky, Susan E. Draheim, Andrew Pike, F. T. COUNTER, A. A. Benedett-Pichler, J S Kasher	1993	61
19	Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines Journal of Medicinal Chemistry ·Per Sauerberg, Preben H. Olesen, M. Hamalengwa, Svend Treppendahl, Malcolm J. Sheardown, Tage Honoré, Charles H. Mitch, John S. Ward, Andrew Pike	1992	131
20	Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride (LY 156758), a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity Journal of Medicinal Chemistry ·Charles D. Jones, حسینعلی پاکروان, Andrew Pike, 鄢家明, Larry J. Black, Allen R. Thompson, Julie F. Falcone, James A. Clemens	1984	240

About Andrew Pike

Andrew Pike is a scholar working on Biological Psychiatry, Cellular and Molecular Neuroscience, Biochemistry, Organic Chemistry and Molecular Biology, having authored 26 papers that have together received 1.8k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (11 papers), Phenothiazines and Benzothiazines Synthesis and Activities (7 papers), Pharmacological Receptor Mechanisms and Effects (6 papers), Synthesis and biological activity (4 papers), Amino Acid Enzymes and Metabolism (3 papers), Receptor Mechanisms and Signaling (3 papers), Synthesis of Indole Derivatives (2 papers) and Molecular Sensors and Ion Detection (2 papers). The work is most often cited by research in Organic Chemistry (917 citations), Nephrology (167 citations), Cellular and Molecular Neuroscience (370 citations), Biological Psychiatry (43 citations) and Biochemistry (73 citations). Andrew Pike has collaborated with scholars based in United Kingdom, United States and Denmark. Frequent co-authors include Yun Zhang, Serge I. Gorelsky, Shathaverdhan Potavathri, Brenton DeBoef, Charles D. Jones, Keith A. Wafford, Caroline Benn, Vivek Dua, John Atack and Peter T. Loudon. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Pharmacology and Experimental Therapeutics, Biopharmaceutics & Drug Disposition and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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