Robert Hertzberg

9.1k total citations · 2 hit papers
40 papers, 7.3k citations indexed

About

Robert Hertzberg is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Robert Hertzberg has authored 40 papers receiving a total of 7.3k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 9 papers in Organic Chemistry and 7 papers in Oncology. Recurrent topics in Robert Hertzberg's work include Cancer therapeutics and mechanisms (12 papers), DNA and Nucleic Acid Chemistry (8 papers) and Computational Drug Discovery Methods (6 papers). Robert Hertzberg is often cited by papers focused on Cancer therapeutics and mechanisms (12 papers), DNA and Nucleic Acid Chemistry (8 papers) and Computational Drug Discovery Methods (6 papers). Robert Hertzberg collaborates with scholars based in United States, United Kingdom and Netherlands. Robert Hertzberg's co-authors include Sidney M. Hecht, Peter B. Dervan, Leroy F. Liu, Y H Hsiang, Mary Jo Caranfa, Andrew J. Pope, Ricardo Macarrón, Kenneth G. Holden, Michael W. Van Dyke and Randall K. Johnson and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Robert Hertzberg

40 papers receiving 7.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

1985 2.0k citations Y H Hsiang, Robert Hertzberg et al. Journal of Biological Chemistry profile →
Impact of high-throughput screening in biomedical research

2011 920 citations Ricardo Macarrón, Martyn Banks et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert Hertzberg United States	24	5.5k	2.4k	1.2k	1.0k	606	40	7.3k
William G. Bornmann United States	66	7.7k 1.4×	3.6k 1.5×	2.9k 2.4×	966 0.9×	647 1.1×	167	14.7k
Lance Stewart United States	39	5.6k 1.0×	1.4k 0.6×	1.1k 0.9×	1.2k 1.2×	639 1.1×	92	6.7k
Melinda G. Hollingshead United States	45	3.9k 0.7×	1.9k 0.8×	1.1k 0.9×	277 0.3×	385 0.6×	167	6.9k
Bruce C. Baguley New Zealand	64	9.1k 1.6×	4.3k 1.8×	3.8k 3.1×	1.1k 1.0×	803 1.3×	384	15.0k
Takao Yamori Japan	57	7.7k 1.4×	2.4k 1.0×	1.9k 1.6×	286 0.3×	1.0k 1.7×	241	11.7k
Randall K. Johnson United States	48	4.7k 0.9×	3.2k 1.3×	2.1k 1.7×	546 0.5×	693 1.1×	142	8.2k
Mary Ann Jordan United States	56	8.6k 1.6×	6.0k 2.5×	2.7k 2.2×	403 0.4×	1.1k 1.8×	115	15.3k
Michael C. Alley United States	28	2.6k 0.5×	1.3k 0.5×	1.3k 1.1×	307 0.3×	643 1.1×	48	5.2k
Nouri Neamati United States	61	6.0k 1.1×	1.4k 0.6×	3.5k 2.8×	214 0.2×	447 0.7×	241	12.1k
Alan Eastman United States	61	9.0k 1.6×	5.2k 2.2×	1.4k 1.1×	269 0.3×	297 0.5×	185	12.5k

Countries citing papers authored by Robert Hertzberg

Since Specialization

Citations

This map shows the geographic impact of Robert Hertzberg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert Hertzberg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert Hertzberg more than expected).

Fields of papers citing papers by Robert Hertzberg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert Hertzberg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert Hertzberg. The network helps show where Robert Hertzberg may publish in the future.

Co-authorship network of co-authors of Robert Hertzberg

This figure shows the co-authorship network connecting the top 25 collaborators of Robert Hertzberg. A scholar is included among the top collaborators of Robert Hertzberg based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert Hertzberg. Robert Hertzberg is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hertzberg, Robert, et al.. (2016). Design and Implementation of High-Throughput Screening Assays. Methods in molecular biology. 1–32. 6 indexed citations

Macarrón, Ricardo, Martyn Banks, Dejan Bojanic, et al.. (2011). Impact of high-throughput screening in biomedical research. Nature Reviews Drug Discovery. 10(3). 188–195. 920 indexed citations breakdown →

Macarrón, Ricardo & Robert Hertzberg. (2010). Design and Implementation of High Throughput Screening Assays. Molecular Biotechnology. 47(3). 270–285. 67 indexed citations

Macarrón, Ricardo & Robert Hertzberg. (2009). Design and Implementation of High-Throughput Screening Assays. Methods in molecular biology. 1439. 1–32. 47 indexed citations

Macarrón, Ricardo & Robert Hertzberg. (2003). Design and Implementation of High Throughput Screening Assays. Humana Press eBooks. 190. 1–29. 11 indexed citations

Ashman, Stephen, Brian Bond, Fernando Ramón, et al.. (2002). A Standard Operating Procedure for Assessing Liquid Handler Performance in High-Throughput Screening. SLAS DISCOVERY. 7(6). 554–569. 41 indexed citations

Taylor, Paul B., et al.. (2000). Automated Assay Optimization with Integrated Statistics and Smart Robotics. SLAS DISCOVERY. 5(4). 213–225. 24 indexed citations

Hertzberg, Robert & Andrew J. Pope. (2000). High-throughput screening: new technology for the 21st century. Current Opinion in Chemical Biology. 4(4). 445–451. 388 indexed citations

White, John R., Judithann M. Lee, Peter R. Young, et al.. (1998). Identification of a Potent, Selective Non-peptide CXCR2 Antagonist That Inhibits Interleukin-8-induced Neutrophil Migration. Journal of Biological Chemistry. 273(17). 10095–10098. 341 indexed citations

10.

Ames, Robert S., Yi Li, Henry M. Sarau, et al.. (1996). Molecular Cloning and Characterization of the Human Anaphylatoxin C3a Receptor. Journal of Biological Chemistry. 271(34). 20231–20234. 207 indexed citations

11.

Bennett, Donald B., Thomas A. Morton, Ann Breen, et al.. (1995). Kinetic characterization of the interaction of biotinylated human interleukin 5 with an Fc chimera of its receptor α subunit and development of an ELISA screening assay using real‐time interaction biosensor analysis. Journal of Molecular Recognition. 8(1-2). 52–58. 9 indexed citations

12.

Culp, J S, Christine Debouck, R K Johnson, et al.. (1994). Kinetic and mutational analysis of human immunodeficiency virus type 1 reverse transcriptase inhibition by inophyllums, a novel class of non-nucleoside inhibitors.. Journal of Biological Chemistry. 269(9). 6325–6331. 46 indexed citations

13.

Eng, Wai-Kwong, F L McCabe, K. B. Tan, et al.. (1990). Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content.. Molecular Pharmacology. 38(4). 471–480. 106 indexed citations

14.

Hertzberg, Robert, Mary Jo Caranfa, & Sidney M. Hecht. (1989). On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry. 28(11). 4629–4638. 482 indexed citations

15.

Hertzberg, Robert, Mary Jo Caranfa, Kenneth G. Holden, et al.. (1989). Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity. Journal of Medicinal Chemistry. 32(3). 715–720. 366 indexed citations

16.

Hurley, Laurence H., David E. Thurston, David R. Langley, et al.. (1988). Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds. Chemical Research in Toxicology. 1(5). 258–268. 117 indexed citations

17.

Tan, K. B., et al.. (1987). Elevated topoisomerase II activity and altered chromatin in nitrogen mustard-resistant human cells.. PubMed. 95–8. 19 indexed citations

18.

Hsiang, Y H, Robert Hertzberg, Sidney M. Hecht, & Leroy F. Liu. (1985). Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.. Journal of Biological Chemistry. 260(27). 14873–14878. 2018 indexed citations breakdown →

19.

Hertzberg, Robert & Peter B. Dervan. (1982). Cleavage of double helical DNA by methidium-propyl-EDTA-iron(II). Journal of the American Chemical Society. 104(1). 313–315. 368 indexed citations

20.

Kundu, Nitya G., et al.. (1980). A new synthesis of n-blocked dihydrouracil and dihydroorotic acid derivatives using lithium tri-sec-butyl borohydride as reducing agent. Tetrahedron Letters. 21(12). 1105–1108. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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