Shiro Soga

1.5k citations

26 papers · 1.2k indexed · h-index 16

Impact in

Molecular Biology top 10%
- Heat shock proteins research
- ATP Synthase and ATPases Research
- Protein Structure and Dynamics
Physical and Theoretical Chemistry top 5%
- thermodynamics and calorimetric analyses

Papers in

Molecular Biology 24
- Heat shock proteins research 15
- Chemical Synthesis and Analysis 2
- Genomics, phytochemicals, and oxidative stress 2
Pharmacology 5
- Microbial Natural Products and Biosynthesis 4

Co-authors: Shiro Akinaga Yukimasa Shiotsu Leonard Μ. Neckers Theodor W. Schulte David O. Toft W. Patrick Sullivan Bridget Stensgard Sreenath V. Sharma
Journals: The Journal of Antibiotics (3 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Current Pharmaceutical Design (2 papers)Cancer Research (2 papers)Blood (2 papers)
Partner nations: Japan United States Indonesia

In The Last Decade

Shiro Soga

25 papers receiving 1.2k citations

Peers

Countries citing papers authored by Shiro Soga

Since Specialization

Citations

This map shows the geographic impact of Shiro Soga's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shiro Soga with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shiro Soga more than expected).

Fields of papers citing papers by Shiro Soga

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shiro Soga. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shiro Soga. The network helps show where Shiro Soga may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Shiro Soga, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Shiro Soga Line = papers co-authored together Shiro Soga links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Downregulation of collagen and elastin genes in murine skin following cisplatin and vincristine treatment Toxicology and Applied Pharmacology ·Филатова-Сафронова Маргарита Александровна, Yuichi Someya, Hiroyasu Sakai, J Green, Masayuki Ueda, Yuichi Chigusa, 亜理子戸田, Shiro Soga, Hinako Nanri, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, Fumiaki Sato, Kumiko Ogawa	2025	0
2	Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin Biological and Pharmaceutical Bulletin ·Luís Cadillon Costa, Филатова-Сафронова Маргарита Александровна, Shiro Soga, Hinako Nanri, Takayuki Ogiwara, 亜理子戸田, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, Hiroyasu Sakai	2024	1
3	The synthesis and evaluation of the antiproliferative activity of deacidified GEX1A analogues The Journal of Antibiotics ·Fernando Saras, Hiroshi Nakagawa, Pasi Mikkola, Yasuo Watanabe, Shiro Soga, Fukushima Kazuhiko, Hideyuki Onodera	2017	6
4	Hsp90 Inhibitors as Anti-Cancer Agents, from Basic Discoveries to Clinical Development Current Pharmaceutical Design ·Shiro Soga, Shiro Akinaga, Yukimasa Shiotsu	2012	61
5	Anti-tumor activity against multiple myeloma by combination of KW-2478, an Hsp90 inhibitor, with bortezomib Blood Cancer Journal ·Toshihiko Ishii, Galina Vladimirovna Drobyshevsky, Takayuki Nakashima, Simone Jüliger, T. T. Chen, Shiro Soga, Shiro Akinaga, Jamie Cavenagh, Γεωργία Γιαννακοπούλου, Yukimasa Shiotsu	2012	43
6	New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells Clinical Cancer Research ·Takayuki Nakashima, Toshihiko Ishii, Nawarat Ekkarntrong, Toshihiro Seike, Hiroshi Nakagawa, Yutaka Kanda, Shiro Akinaga, Shiro Soga, Yukimasa Shiotsu	2010	69
7	Conformational significance of EH21A1–A4, phenolic derivatives of geldanamycin, for Hsp90 inhibitory activity Bioorganic & Medicinal Chemistry Letters ·Hideyuki Onodera, Masami Kaneko, Yuichi Takahashi, Jiang Huang, Jun Funahashi, Takayuki Nakashima, Shiro Soga, Makoto Suzuki, Shun‐ichi Ikeda, Yoshinori Yamashita, Endang Sutriswati Rahayu, Yutaka Kanda, Michio Ichimura	2008	17
8	Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone Proceedings of the National Academy of Sciences ·Akihiro Yano, Shinji Tsutsumi, Shiro Soga, Min-Jung Lee, Jane B. Trepel, Hiroyuki Osada, Len Neckers	2008	70
9	Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition British Journal of Cancer ·Weiguo Xu, Shiro Soga, Kristen Beebe, Ming‐Jen Lee, Young S. Kim, Jane B. Trepel, Len Neckers	2007	33
10	Development of Radicicol Analogues Current Cancer Drug Targets ·Shiro Soga, Yukimasa Shiotsu, Shiro Akinaga, Sreenath V. Sharma	2003	100
11	Improvement of biological activity and proteolytic stability of peptides by coupling with a cyclic peptide Bioorganic & Medicinal Chemistry Letters ·Kenji Shibata, Toshiyuki Suzawa, Shiro Soga, Tamio Mizukami, Koji Yamada, Nobuo Hanai, Motoo Yamasaki	2003	19
12	Heat Shock Protein 90-antagonist Destabilizes Bcr-Abl/HSP90 Chaperone Complex Leukemia & lymphoma ·Yukimasa Shiotsu, Shiro Soga, Shiro Akinaga	2002	20
13	A Radicicol Derivative, KF58333, Inhibits Expression of Hypoxia‐inducible Factor‐1α and Vascular Endothelial Growth Factor, Angiogenesis and Growth of Human Breast Cancer Xenografts Japanese Journal of Cancer Research ·Junichi Kurebayashi, 哲雄山口, Masafumi Kurosumi, Shiro Soga, Shiro Akinaga, Hiroshi Sonoo	2001	48
14	Stereospecific antitumor activity of radicicol oxime derivatives Cancer Chemotherapy and Pharmacology ·Shiro Soga, Sreenath V. Sharma, Yukimasa Shiotsu, Makiko Shimizu, Harunobu Tahara, Kazuo Yamaguchi, Miranda Wilhelm, Chikara Murakata, Tatsuya Tamaoki, Junichi Kurebayashi, Theodor W. Schulte, Leonard Μ. Neckers, Shiro Akinaga	2001	50
15	UCF116, New Inhibitors of Farnesyltransferase Produced by Streptomyces. The Journal of Antibiotics ·Mitsunobu Hara, Shiro Soga, 哲安藤, MohammadAmiri Mikal, Robert McEnany, Tamio Mizukami	2000	15
16	ChemInform Abstract: UCF116, New Inhibitors of Farnesyltransferase Produced by Streptomyces ChemInform ·Mitsunobu Hara, Shiro Soga, 哲安藤, MohammadAmiri Mikal, Robert McEnany, Tamio Mizukami	2000	1
17	Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G1 phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex Blood ·Yukimasa Shiotsu, Leonard Μ. Neckers, Ivo Wortman, Won Gun An, Theodor W. Schulte, Shiro Soga, Chikara Murakata, Tatsuya Tamaoki, Shiro Akinaga	2000	5
18	Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin Cell Stress and Chaperones ·Theodor W. Schulte, Shiro Akinaga, Shiro Soga, W. Patrick Sullivan, Bridget Stensgard, David O. Toft, Leonard Μ. Neckers	1998	329
19	Radicicol Leads to Selective Depletion of Raf Kinase and Disrupts K-Ras-activated Aberrant Signaling Pathway Journal of Biological Chemistry ·Shiro Soga, 敏一戸, WILLAM K. ROLPH, Shiro Akinaga, Kenji Irie, Kunihiro Matsumoto, Sreenath V. Sharma, Hirofumi Nakano, Tamio Mizukami, Mitsunobu Hara	1998	85
20	Cloning, nucleotide sequence, and expression in escherichia coli of DNA polymerase gene (polA) from thermus thermophilus HB8 Journal of Fermentation and Bioengineering ·K H BAUER, H. Komatsubara, Shiro Soga, Tetsuya Yomo, Masanori Oka, K Weyer, Itaru Urabe	1993	17

About Shiro Soga

Shiro Soga is a scholar working on Molecular Biology, Pharmacology, Computational Theory and Mathematics, Immunology and Cell Biology, having authored 26 papers that have together received 1.2k indexed citations. Recurring topics across this work include Heat shock proteins research (15 papers), Toxin Mechanisms and Immunotoxins (5 papers), Microbial Natural Products and Biosynthesis (4 papers), Computational Drug Discovery Methods (4 papers), Click Chemistry and Applications (3 papers), Chemical Synthesis and Analysis (2 papers), Genomics, phytochemicals, and oxidative stress (2 papers) and Cancer, Hypoxia, and Metabolism (2 papers). The work is most often cited by research in Molecular Biology (1.0k citations), Physical and Theoretical Chemistry (102 citations), Toxicology (35 citations), Immunology (202 citations) and Computational Theory and Mathematics (144 citations). Shiro Soga has collaborated with scholars based in Japan, United States and Indonesia. Frequent co-authors include Shiro Akinaga, Yukimasa Shiotsu, Leonard Μ. Neckers, Theodor W. Schulte, David O. Toft, W. Patrick Sullivan, Bridget Stensgard, Sreenath V. Sharma, Chikara Murakata and Tamio Mizukami. Their work appears in journals such as The Journal of Antibiotics, Bioorganic & Medicinal Chemistry Letters, Current Pharmaceutical Design, Cancer Research and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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