David O. Toft

17.5k total citations · 4 hit papers
124 papers, 14.4k citations indexed

About

David O. Toft is a scholar working on Molecular Biology, Genetics and Immunology. According to data from OpenAlex, David O. Toft has authored 124 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Molecular Biology, 30 papers in Genetics and 17 papers in Immunology. Recurrent topics in David O. Toft's work include Heat shock proteins research (67 papers), Estrogen and related hormone effects (30 papers) and Toxin Mechanisms and Immunotoxins (16 papers). David O. Toft is often cited by papers focused on Heat shock proteins research (67 papers), Estrogen and related hormone effects (30 papers) and Toxin Mechanisms and Immunotoxins (16 papers). David O. Toft collaborates with scholars based in United States, France and Canada. David O. Toft's co-authors include William B. Pratt, W. Patrick Sullivan, Bert W. O’Malley, Sara J. Felts, Bridget Stensgard, Hideo Nishigori, Brian Freeman, David F. Smith, Brian Johnson and Barbara Owen and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

David O. Toft

124 papers receiving 13.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

1997 1.4k citations David O. Toft et al. profile →
Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery

2003 1.2k citations David O. Toft et al. profile →
HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

2005 936 citations David O. Toft et al. profile →
Hormone Receptors: Studies on the Interaction of Estrogen with the Uterus

1968 413 citations David O. Toft et al. profile →

Peers

Countries citing papers authored by David O. Toft

Since Specialization

Citations

This map shows the geographic impact of David O. Toft's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David O. Toft with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David O. Toft more than expected).

Fields of papers citing papers by David O. Toft

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David O. Toft. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David O. Toft. The network helps show where David O. Toft may publish in the future.

Co-authorship network of co-authors of David O. Toft

This figure shows the co-authorship network connecting the top 25 collaborators of David O. Toft. A scholar is included among the top collaborators of David O. Toft based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David O. Toft. David O. Toft is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells 2010 ·Molecular and Cellular Biology ·Ni Li, Chunsong Yang, Daniel Gioeli, Henry F. Frierson, David O. Toft, Bryce M. Paschal	129
2	Characterization of plant p23-like proteins for their co-chaperone activities 2010 ·Cell Stress and Chaperones ·Zhongming Zhang, W. Patrick Sullivan, Sara J. Felts, Bishun Deo Prasad, David O. Toft, Priti Krishna	21
3	P-Glycoprotein–Mediated Resistance to Hsp90-Directed Therapy Is Eclipsed by the Heat Shock Response 2008 ·Cancer Research ·Andrea K. McCollum, Cynthia J. TenEyck, Bridget Stensgard, Bruce W. Morlan, Karla V. Ballman, Robert B. Jenkins, David O. Toft, Charles Erlichman	57
4	GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity 2008 ·Journal of Biological Chemistry ·Ahmed Chadli, Sara J. Felts, David O. Toft	38
5	Functioning of the Hsp90 machine in chaperoning checkpoint kinase 1 (Chk1) and the progesterone receptor (PR) 2007 ·Cell Stress and Chaperones ·Sara J. Felts, Larry M. Karnitz, David O. Toft	21
6	Defining the Requirements for Hsp40 and Hsp70 in the Hsp90 Chaperone Pathway 2006 ·Journal of Biological Chemistry ·(unknown), David O. Toft	57
7	Chaperoning Checkpoint Kinase 1 (Chk1), an Hsp90 Client, with Purified Chaperones 2005 ·Journal of Biological Chemistry ·Sonnet J.H. Arlander, Sara J. Felts, Jill M. Wagner, Bridget Stensgard, David O. Toft, Larry M. Karnitz	70
8	Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70 2004 ·Cell Stress and Chaperones ·Amerigo Carrello, (unknown), (unknown), Barbara Owen, D. Mok, Bryan K. Ward, Rodney F. Minchin, David O. Toft, Thomas Ratajczak	48
9	Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress 2003 ·Journal of Biological Chemistry ·Sonnet J.H. Arlander, Alex Eapen, Benjamin T. Vroman, Robert J. McDonald, David O. Toft, Larry M. Karnitz	136
10	Effect of geldanamycin on androgen receptor function and stability 2002 ·Cell Stress and Chaperones ·Donkena Krishna Vanaja, (unknown), David O. Toft, Charles Y.F. Young	109
11	HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor 2002 ·Journal of Biological Chemistry ·(unknown), Ahmed Chadli, David O. Toft	112
12	The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties 2000 ·Journal of Biological Chemistry ·Sara J. Felts, Barbara Owen, Phuongmai Nguyen, Jane B. Trepel, David B. Donner, David O. Toft	290
13	The Importance of ATP Binding and Hydrolysis by Hsp90 in Formation and Function of Protein Heterocomplexes 1999 ·Journal of Biological Chemistry ·James P. Grenert, Brian Johnson, David O. Toft	188
14	The Assembly of Progesterone Receptor-hsp90 Complexes Using Purified Proteins 1998 ·Journal of Biological Chemistry ·Hiroshi Kosano, Bridget Stensgard, M. Cristine Charlesworth, (unknown), David O. Toft	202
15	Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya 1998 ·Cell Stress and Chaperones ·(unknown), Gary H. Perdew, David O. Toft, Julie C. Silver	8
16	Identification of a Complex between Centrin and Heat Shock Proteins in CSF-Arrested Xenopus Oocytes and Dissociation of the Complex Following Oocyte Activation 1995 ·Developmental Biology ·(unknown), Jayleen Grams, Benjamin J. Madden, David O. Toft, Jeffrey L. Salisbury	46
17	Immunocytochemical localization of estrogen-induced progestin receptors in guinea pig brain 1988 ·Brain Research ·Jeffrey D. Blaustein, Joan C. King, David O. Toft, Joanne C. Turcotte	126
18	Hormone‐dependent processing of the avian progesterone receptor 1988 ·Journal of Cellular Biochemistry ·W. Patrick Sullivan, David F. Smith, Thomas G. Beito, Christopher J. Krco, David O. Toft	62
19	The Production of Antibodies Against the Conserved Cysteine Region of Steroid Receptors and Their Use in Characterizing the Avian Progesterone Receptor* 1988 ·Endocrinology ·David F. Smith, Dennis B. Lubahn, Daniel McCormick, Elizabeth M. Wilson, David O. Toft	41
20	Structure-Function Properties of the Chicken Progesterone Receptor A Synthesized from Complementary Deoxyribonucleic Acid 1987 ·Molecular Endocrinology ·(unknown), Ming‐Jer Tsai, Orla M. Conneely, Beth Lynn Maxwell, James H. Clark, Alan D. W. Dobson, Alex Elbrecht, David O. Toft, William T. Schrader, Bert W. O’Malley	46

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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