Hiroyuki Osada

25.5k total citations · 1 hit paper
663 papers, 19.5k citations indexed

About

Hiroyuki Osada is a scholar working on Molecular Biology, Pharmacology and Organic Chemistry. According to data from OpenAlex, Hiroyuki Osada has authored 663 papers receiving a total of 19.5k indexed citations (citations by other indexed papers that have themselves been cited), including 423 papers in Molecular Biology, 196 papers in Pharmacology and 126 papers in Organic Chemistry. Recurrent topics in Hiroyuki Osada's work include Microbial Natural Products and Biosynthesis (171 papers), Cancer therapeutics and mechanisms (41 papers) and Fungal Biology and Applications (40 papers). Hiroyuki Osada is often cited by papers focused on Microbial Natural Products and Biosynthesis (171 papers), Cancer therapeutics and mechanisms (41 papers) and Fungal Biology and Applications (40 papers). Hiroyuki Osada collaborates with scholars based in Japan, United States and Belarus. Hiroyuki Osada's co-authors include Hideaki Kakeya, Cheng‐Bin Cui, Siro Simizu, Takeo Usui, Takashi Takahashi, Makoto Muroi, Makoto Kawatani, T Sudo, Nobumoto Watanabe and Tamio Saito and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Hiroyuki Osada

648 papers receiving 19.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 739 citations Hiroyuki Osada et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Hiroyuki Osada

Since Specialization

Citations

This map shows the geographic impact of Hiroyuki Osada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroyuki Osada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroyuki Osada more than expected).

Fields of papers citing papers by Hiroyuki Osada

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroyuki Osada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroyuki Osada. The network helps show where Hiroyuki Osada may publish in the future.

Co-authorship network of co-authors of Hiroyuki Osada

This figure shows the co-authorship network connecting the top 25 collaborators of Hiroyuki Osada. A scholar is included among the top collaborators of Hiroyuki Osada based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hiroyuki Osada. Hiroyuki Osada is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	GENI as an AMPK Activator Binds α and γ Subunits and Improves the Memory Dysfunction of Alzheimer’s Disease Mouse Models via Autophagy and Neuroprotection 2025 ·Antioxidants ·Ying Wang, (unknown), Danni Chen, (unknown), (unknown), Hiroyuki Osada, Minoru Yoshida, Lan Xiang, Jianhua Qi	1
2	Amiodarone inhibits the Toll-like receptor 3-mediated nuclear factor κB signaling pathway by blocking organelle acidification 2024 ·Biochemical and Biophysical Research Communications ·(unknown), Keiko Takaki, (unknown), (unknown), Hiroyuki Hirano, Hiroyuki Osada, Takao Kataoka	1
3	Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis 2023 ·Biochemical Pharmacology ·(unknown), (unknown), (unknown), (unknown), Yuta Matsuura, (unknown), (unknown), Ryosuke Fukuda, (unknown), (unknown), (unknown), (unknown), Shunsuke Aoki, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Hiroyuki Kumeta, Tomohide Saio, Tsukasa Okiyoneda	11
4	cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo 2023 ·PLoS ONE ·Naoki Kato, (unknown), Toshihiko Nogawa, Yushi Futamura, (unknown), (unknown), Harumi Aono, Yuuta Fujikawa, Hideshi Inoue, Kazuhiko Matsuda, Hiroyuki Osada, Ryusuke Niwa, Shunji Takahashi	2
5	Targeting Epigenetic and Posttranscriptional Gene Regulation by PSF Impairs Hormone Therapy–Refractory Cancer Growth 2021 ·Cancer Research ·Ken‐ichi Takayama, Teruki Honma, Takashi Suzuki, Yasumitsu Kondoh, Hiroyuki Osada, Yutaka Suzuki, Minoru Yoshida, Satoshi Inoue	15
6	The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells 2021 ·Biomedicines ·Lihong Cheng, Hiroyuki Osada, (unknown), Minoru Yoshida, Lan Xiang, Jianhua Qi	9
7	Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons** 2021 ·Angewandte Chemie International Edition ·(unknown), Naoki Kato, Suyong Re, (unknown), Kohei Watanabe, Ryo Takita, Toshihiko Nogawa, Tomoya Hino, Hiroyuki Osada, Yuji Sugita, Shunji Takahashi, Shingo Nagano	20
8	Aromatic butenolides produced by a soil ascomycete Auxarthron sp. KCB15F070 derived from a volcanic island 2019 ·Tetrahedron Letters ·(unknown), Sangkeun Son, (unknown), (unknown), (unknown), Atsuya Muranaka, Masanobu Uchiyama, Jung‐Sook Lee, Mina Jang, Sung‐Kyun Ko, Shunji Takahashi, Hiroyuki Osada, Jae‐Hyuk Jang, Jong Seog Ahn	5
9	An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s 2019 ·Scientific Reports ·Naoki Kanoh, (unknown), (unknown), Yusuke Takahashi, Takeshi Miyazawa, Takemichi Nakamura, Takashi J. Moriya, Hiroyuki Hirano, Hiroyuki Osada, Yoshiharu Iwabuchi, Shunji Takahashi	5
10	Anti-Angiogenesis Effects Induced by Octaminomycins A and B against HUVECs 2018 ·Journal of Microbiology and Biotechnology ·Jun‐Pil Jang, Jang Mi Han, Hye Jin Jung, Hiroyuki Osada, Jae‐Hyuk Jang, Jong Seog Ahn	5
11	MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action 2017 ·Bioinformatics ·Justin Nelson, Scott W. Simpkins, (unknown), Sheena C. Li, Jeff S. Piotrowski, Hiroyuki Hirano, Yoko Yashiroda, Hiroyuki Osada, Minoru Yoshida, Charles Boone, Chad L. Myers	9
12	Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein 2017 ·Pesticide Biochemistry and Physiology ·Kazuyuki Maeda, Yuichi Nakajima, Takayuki Motoyama, Yasumitsu Kondoh, Tatsuro Kawamura, Kyoko Kanamaru, Shuichi Ohsato, Takumi Nishiuchi, Minoru Yoshida, Hiroyuki Osada, Tetsuo Kobayashi, Makoto Kimura	8
13	Controversies in ASSAY and Drug Development Technologies : A Focus on Assessing Irreproducibility 2014 ·Assay and Drug Development Technologies ·J. Fraser Glickman, Thomas Lundbäck, Andrew D. Napper, (unknown), Anton Simeonov, C. David Weaver, Hongwei Yin, Guido J.R. Zaman, Hiroyuki Osada	1
14	Target identification of small molecules based on chemical biology approaches 2013 ·Molecular BioSystems ·Yushi Futamura, Makoto Muroi, Hiroyuki Osada	57
15	Involvement of Disulfide Bond Formation in the Activation of Heparanase 2007 ·Cancer Research ·Siro Simizu, Takehiro Suzuki, Makoto Muroi, Ngit Shin Lai, Satoshi Takagi, Naoshi Dohmae, Hiroyuki Osada	43
16	Reveromycin A Inhibits Osteolytic Bone Metastasis of Small-Cell Lung Cancer Cells, SBC-5, through an Antiosteoclastic Activity 2005 ·Clinical Cancer Research ·Hiroaki Muguruma, Seiji Yano, Soji Kakiuchi, Hisanori Uehara, Makoto Kawatani, Hiroyuki Osada, Saburo Sone	39
17	RECK-Mediated Suppression of Tumor Cell Invasion Is Regulated by Glycosylation in Human Tumor Cell Lines 2005 ·Cancer Research ·Siro Simizu, Satoshi Takagi, Yuki Tamura, Hiroyuki Osada	53
18	M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF ^β-TrCP 2004 ·Proceedings of the National Academy of Sciences ·Nobumoto Watanabe, (unknown), (unknown), Makoto Taniguchi, Naoko Watanabe, Tony Hunter, Hiroyuki Osada	385
19	Molecular analysis of the FHIT gene at 3p14.2 in lung cancer cell lines. 1996 ·PubMed ·K Yanagisawa, (unknown), Hiroyuki Osada, Ken Uchida, Kiyoshi Takagi, A. Masuda, Takashi Takahashi	46
20	Structure and biological activity of ascamycin, a new nucleoside antibiotic. 1984 ·PubMed ·K. ISONO, Masakazu Uramoto, Hiroyuki Osada, Makoto Ubukata, Hiroo Kusakabe, (unknown), (unknown), Satinder K. Sethi, James A. McCloskey	2

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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