Sheila Seal

36.3k citations

30 papers · 4.9k indexed · 3 hit papers · h-index 25

Co-authors: Michael R. Stratton Nazneen Rahman Douglas F. Easton Rita Barfoot Anthony Renwick D. Gareth Evans Patrick Kelly Diana Eccles
Topics: BRCA gene mutations in cancer (20 papers)DNA Repair Mechanisms (11 papers)Cancer Genomics and Diagnostics (8 papers)
Cited by: Genetics Cancer Research Reproductive Medicine
Journals: Nature Communications Nature Genetics Journal of Clinical Oncology
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Sheila Seal

30 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

2006 689 citations Nazneen Rahman, Sheila Seal et al. Nature Genetics profile →
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

2006 513 citations Sheila Seal, Deborah J. Thompson et al. Nature Genetics profile →
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles

2006 511 citations Anthony Renwick, Deborah J. Thompson et al. Nature Genetics profile →

Peers

Countries citing papers authored by Sheila Seal

Since Specialization

Citations

This map shows the geographic impact of Sheila Seal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sheila Seal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sheila Seal more than expected).

Fields of papers citing papers by Sheila Seal

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sheila Seal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sheila Seal. The network helps show where Sheila Seal may publish in the future.

Co-authorship network of co-authors of Sheila Seal

This figure shows the co-authorship network connecting the top 25 collaborators of Sheila Seal. A scholar is included among the top collaborators of Sheila Seal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sheila Seal. Sheila Seal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability 2017 ·The American Journal of Human Genetics ·Katrina Tatton‐Brown,Chey Loveday,Shawn Yost,Matthew Clarke,Emma Ramsay,Anna Zachariou,Anna Elliott,Harriet Wylie,Anna Ardissone,Olaf Rittinger,Fiona Stewart,I. Karen Temple,Trevor Cole,Shazia Mahamdallie,Sheila Seal,Elise Ruark,Nazneen Rahman	128
2	Implementing rapid, robust, cost-effective, patient-centred, routine genetic testing in ovarian cancer patients 2016 ·Scientific Reports ·Angela George,(unknown),Sheila Seal,Sabrina Talukdar,Shazia Mahamdallie,Elise Ruark,(unknown),Ingrid Slade,Zoe Kemp,Martin Gore,Ann Strydom,Susana Banerjee,Helen Hanson,Nazneen Rahman	157
3	CSN and CAVA: variant annotation tools for rapid, robust next-generation sequencing analysis in the clinical setting 2015 ·Genome Medicine ·Márton Münz,Elise Ruark,Anthony Renwick,Emma Ramsay,Matthew Clarke,Shazia Mahamdallie,(unknown),Sheila Seal,Ann Strydom,Gerton Lunter,Nazneen Rahman	29
4	Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour 2014 ·Nature Communications ·Sandra Hanks,Elizabeth R Perdeaux,Sheila Seal,Elise Ruark,Shazia Mahamdallie,Anne R. Murray,Emma Ramsay,(unknown),Anna Zachariou,(unknown),Margaret Warren-Perry,Anna Elliott,Alan Davidson,Helen P. Price,Charles Stiller,Kathy Pritchard‐Jones,Nazneen Rahman	64
5	Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14 2013 ·Nature Genetics ·Elise Ruark,Sheila Seal,Heather McDonald,Feng Zhang,(unknown),(unknown),Elizabeth R Perdeaux,Elizabeth Rapley,Rosalind A. Eeles,Julian Peto,Zsofia Kote‐Jarai,Kenneth Muir,Jérémie Nsengimana,Janet Shipley,D. Timothy Bishop,Michael R. Stratton,Douglas F. Easton,Robert Huddart,Nazneen Rahman,Clare Turnbull	115
6	Predisposition gene identification in common cancers by exome sequencing: insights from familial breast cancer 2012 ·Breast Cancer Research and Treatment ·Katie Snape,Elise Ruark,Patrick Tarpey,Anthony Renwick,Clare Turnbull,Sheila Seal,Anne R. Murray,Sandra Hanks,Jenny Douglas,Michael R. Stratton,Nazneen Rahman	36
7	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer 2010 ·Nature Genetics ·Clare Turnbull,Elizabeth Rapley,Sheila Seal,David Pernet,Anthony Renwick,Deborah Hughes,Michelle Ricketts,Rachel Linger,Jérémie Nsengimana,Panos Deloukas,Robert Huddart,D. Timothy Bishop,Douglas F. Easton,Michael R. Stratton,Nazneen Rahman	235
8	Mutation and association analysis of GEN1 in breast cancer susceptibility 2010 ·Breast Cancer Research and Treatment ·Clare Turnbull,Sarah Hines,Anthony Renwick,Deborah Hughes,David Pernet,Anna Elliott,Sheila Seal,Margaret Warren-Perry,D. Gareth Evans,Diana Eccles,Michael R. Stratton,Nazneen Rahman	14
9	A genome-wide association study of testicular germ cell tumor 2009 ·Nature Genetics ·Elizabeth Rapley,Clare Turnbull,Ali Amin Al Olama,Emmanouil T. Dermitzakis,Rachel Linger,Robert Huddart,Anthony Renwick,Deborah Hughes,Sarah Hines,Sheila Seal,Jonathan J. Morrison,Jérémie Nsengimana,Panos Deloukas,Nazneen Rahman,D. Timothy Bishop,Douglas F. Easton,Michael R. Stratton	233
10	Biallelic mutations in PALB2 cause Fanconi anemia and predispose to childhood cancer 2007 ·Cancer Research ·Sarah Reid,Detlev Schindler,Helmut Hanenberg,Marc Tischkowitz,Sandra Hanks,Karen Barker,Patrick Kelly,Sheila Seal,Sat Dev Batish,Francis P. Lach,Reinhard Kalb,Kornelia Neveling,Christopher G. Mathew,Arleen D. Auerbach,Nazneen Rahman	1
11	PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility genebreakdown → 2006 ·Nature Genetics ·Nazneen Rahman,Sheila Seal,Deborah J. Thompson,Patrick Kelly,Anthony Renwick,Anna Elliott,Sarah Reid,(unknown),Rita Barfoot,Tasnim Chagtai,Hiran Jayatilake,Lesley McGuffog,Sandra Hanks,D. Gareth Evans,Diana Eccles,Douglas F. Easton,Michael R. Stratton	689
12	ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility allelesbreakdown → 2006 ·Nature Genetics ·Anthony Renwick,Deborah J. Thompson,Sheila Seal,Patrick Kelly,Tasnim Chagtai,Munaza Ahmed,Bernard V. North,Hiran Jayatilake,Rita Barfoot,(unknown),Lesley McGuffog,D. Gareth Evans,Diana Eccles,Douglas F. Easton,Michael R. Stratton,Nazneen Rahman	511
13	Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility allelesbreakdown → 2006 ·Nature Genetics ·Sheila Seal,Deborah J. Thompson,Anthony Renwick,Anna Elliott,Patrick Kelly,Rita Barfoot,Tasnim Chagtai,Hiran Jayatilake,Munaza Ahmed,(unknown),Bernard V. North,Lesley McGuffog,D. Gareth Evans,Diana Eccles,Douglas F. Easton,Michael R. Stratton,Nazneen Rahman	513
14	BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives 2006 ·European Journal of Cancer ·Fiona Lalloo,Jennifer M. Varley,Anthony Moran,David Ellis,(unknown),Paul D.P. Pharoah,Antonis C. Antoniou,(unknown),A Shenton,Sheila Seal,Barbara Bulman,Anthony Howell,D. Gareth Evans	119
15	Variants in CHEK2 Other than 1100delC Do Not Make a Major Contribution to Breast Cancer Susceptibility 2003 ·The American Journal of Human Genetics ·Mieke Schutte,Sheila Seal,Rita Barfoot,Hanne Meijers‐Heijboer,Marijke Wasielewski,D. Gareth Evans,Diana Eccles,Carel Meijers,Frans P. Lohman,Jan G.M. Klijn,Ans van den Ouweland,P. Andrew Futreal,Katherine L. Nathanson,Barbara L. Weber,Douglas F. Easton,Michael R. Stratton,Nazneen Rahman	97
16	Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22 2000 ·Oncogene ·Nazneen Rahman,M. Dawn Teare,Sheila Seal,Hélène Renard,Jon Mangion,(unknown),Deborah J. Thompson,Yin Yao Shugart,Diana Eccles,Peter Devilee,(unknown),Katherine L. Nathanson,Susan L. Neuhausen,Barbara Weber,Jenny C. Chang,Douglas F. Easton,David E. Goldgar,Michael R. Stratton	33
17	Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene 1997 ·Nature Genetics ·Simon A. Gayther,(unknown),Paul A. Russell,Sheila Seal,Rita Barfoot,Bruce A.J. Ponder,Michael R. Stratton,Douglas F. Easton	317
18	BRCA2 mutations in primary breast and ovarian cancers 1996 ·Nature Genetics ·Johnathan M. Lancaster,Richard Wooster,(unknown),Catherine M. Phelan,Charles Cochran,Curtis Gumbs,Sheila Seal,Rita Barfoot,Nadine Collins,Graham R. Bignell,Sandeep Patel,Rifat Hamoudi,Catharina Larsson,Roger W. Wiseman,Andrew Berchuck,J. Dirk Iglehart,Jeffrey R. Marks,Alan Ashworth,Michael R. Stratton,P. Andrew Futreal	280
19	Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation 1995 ·Nature Genetics ·Simon A. Gayther,William Warren,Sylvie Mazoyer,Paul A. Russell,Patricia Harrington,Mathias Chiano,Sheila Seal,Rifat Hamoudi,Elizabeth J. van Rensburg,Alison M. Dunning,Richard R. Love,D. Gareth Evans,Doug Easton,David Clayton,Michael R. Stratton,Bruce A.J. Ponder	376
20	Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q 1994 ·Nature Genetics ·Michael R. Stratton,Deborah Ford,(unknown),Sheila Seal,Richard Wooster,Lori S. Friedman,Mary‐Claire King,(unknown),Peter Devilee,Ross McManus,Peter A. Daly,Elizabeth Smyth,Bruce A.J. Ponder,Julian Peto,Lisa Cannon‐Albright,Douglas F. Easton,David E. Goldgar	107

About Sheila Seal

Sheila Seal is a scholar working on Genetics, Reproductive Medicine and Cancer Research, having authored 30 papers that have together received 4.9k indexed citations. Recurring topics across this work include BRCA gene mutations in cancer (20 papers), DNA Repair Mechanisms (11 papers) and Cancer Genomics and Diagnostics (8 papers). The work is most often cited by research in Genetics (3.3k citations), Cancer Research (1.3k citations) and Reproductive Medicine (534 citations). Sheila Seal has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Michael R. Stratton, Nazneen Rahman, Douglas F. Easton, Rita Barfoot, Anthony Renwick, D. Gareth Evans, Patrick Kelly, Diana Eccles, Hiran Jayatilake and Deborah J. Thompson. Their work appears in journals such as Nature Communications, Nature Genetics and Journal of Clinical Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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