Shahin Rafii

59.0k total citations · 21 hit papers
304 papers, 39.1k citations indexed

About

Shahin Rafii is a scholar working on Molecular Biology, Hematology and Oncology. According to data from OpenAlex, Shahin Rafii has authored 304 papers receiving a total of 39.1k indexed citations (citations by other indexed papers that have themselves been cited), including 199 papers in Molecular Biology, 83 papers in Hematology and 74 papers in Oncology. Recurrent topics in Shahin Rafii's work include Angiogenesis and VEGF in Cancer (99 papers), Hematopoietic Stem Cell Transplantation (48 papers) and Platelet Disorders and Treatments (36 papers). Shahin Rafii is often cited by papers focused on Angiogenesis and VEGF in Cancer (99 papers), Hematopoietic Stem Cell Transplantation (48 papers) and Platelet Disorders and Treatments (36 papers). Shahin Rafii collaborates with scholars based in United States, Qatar and Germany. Shahin Rafii's co-authors include David Lyden, Malcolm A.S. Moore, Beate Heissig, Koichi Hattori, Jason M. Butler, Sérgio Dias, Bi‐Sen Ding, Ronald G. Crystal, Larry Witte and Daniel J. Hicklin and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Shahin Rafii

298 papers receiving 38.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors

2000 1.8k citations Malcolm A.S. Moore, Shahin Rafii et al. Blood profile →
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 1.5k citations David Lyden, Neil R. Hackett et al. profile →
Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

2002 1.4k citations Matthias Friedrich, Neil R. Hackett et al. profile →
Evidence for Circulating Bone Marrow-Derived Endothelial Cells

1998 1.3k citations Shahin Rafii et al. Blood profile →
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration

2003 1.3k citations Shahin Rafii, David Lyden profile →
Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis

2003 1.2k citations Mónica Garcı́a-Barros, François Paris et al. Science profile →
CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors

2008 731 citations Jason M. Butler, Andrea T. Hooper et al. Journal of Clinical Investigation profile →
Angiocrine functions of organ-specific endothelial cells

2016 660 citations Shahin Rafii, Jason M. Butler et al. profile →
Vascular Trauma Induces Rapid but Transient Mobilization of VEGFR2 ⁺ AC133 ⁺ Endothelial Precursor Cells

2001 651 citations Shahin Rafii et al. profile →
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

2010 613 citations Daniel J. Nolan, Jason M. Butler et al. profile →
Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets

1997 596 citations Malcolm A.S. Moore, Shahin Rafii et al. Proceedings of the National Academy of Sciences profile →
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

2003 582 citations Scott T. Avecilla, Koji Shido et al. profile →
The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

1998 536 citations Shahin Rafii, Malcolm A.S. Moore et al. Blood profile →
Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells

2001 530 citations Neil R. Hackett, David Lyden et al. profile →
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?

2002 522 citations Shahin Rafii, David Lyden et al. profile →
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

2010 488 citations Jason M. Butler, Daniel J. Nolan et al. Cell stem cell profile →
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

2013 482 citations Raphaël Lis, Daniel J. Nolan et al. profile →
Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells

2009 467 citations Andrea T. Hooper, Jason M. Butler et al. Cell stem cell profile →
Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

2013 460 citations Daniel J. Nolan, Michael Ginsberg et al. profile →
Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

2001 434 citations Jae-Hung Shieh, Neil R. Hackett et al. Blood profile →
Endothelial-Derived Angiocrine Signals Induce and Sustain Regenerative Lung Alveolarization

2011 382 citations Daniel J. Nolan, Zev Rosenwaks et al. profile →

Peers

Countries citing papers authored by Shahin Rafii

Since Specialization

Citations

This map shows the geographic impact of Shahin Rafii's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shahin Rafii with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shahin Rafii more than expected).

Fields of papers citing papers by Shahin Rafii

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shahin Rafii. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shahin Rafii. The network helps show where Shahin Rafii may publish in the future.

Co-authorship network of co-authors of Shahin Rafii

This figure shows the co-authorship network connecting the top 25 collaborators of Shahin Rafii. A scholar is included among the top collaborators of Shahin Rafii based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shahin Rafii. Shahin Rafii is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A non-canonical aryl hydrocarbon receptor pathway authorizes and safeguards clinical-scale expansion of functional human endothelial cells 2025 ·Nature Cardiovascular Research ·Yang Lin, Fuqiang Geng, Jae-Hung Shieh, Lisa K. Torres, (unknown), Meng Gao, Matthew Wingo, (unknown), (unknown), Raúl Chávez, Renat Shaykhiev, Aleksandra Kopacz, (unknown), David Redmond, Ryan Schreiner, Shahin Rafii	0
2	SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline 2023 ·Biology of Reproduction ·(unknown), Makiko Yamada, Thierry N’Tumba-Byn, (unknown), Meng Gao, Yang Hu, Pauline Marangoni, Ying Liu, Todd Evans, Shahin Rafii, Ophir D. Klein, Henning U. Voss, Anna‐Katerina Hadjantonakis, Olivier Elemento, L. A. Martin, Marco Seandel	3
3	Cooperative ETS transcription factors enforce adult endothelial cell fate and cardiovascular homeostasis 2022 ·Nature Cardiovascular Research ·Jesús M. Gómez-Salinero, Tomer Itkin, Sean Houghton, Chaitanya R. Badwe, Yang Lin, Viktoria Kalna, Neil Dufton, Claire Peghaire, Masataka Yokoyama, Matthew Wingo, Tyler M. Lu, Ge Li, Jenny Xiang, Yen‐Michael S. Hsu, David Redmond, Ryan Schreiner, Graeme M. Birdsey, Anna M. Randi, Shahin Rafii	14
4	Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction 2022 ·Cell stem cell ·Jesús M. Gómez-Salinero, Franco Izzo, Yang Lin, Sean Houghton, Tomer Itkin, Fuqiang Geng, Yaron Bram, (unknown), Tyler M. Lu, Giorgio Inghirami, Jenny Xiang, Raphaël Lis, David Redmond, Ryan Schreiner, Sina Y. Rabbany, Dan A. Landau, Robert E. Schwartz, Shahin Rafii	39
5	Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics 2022 ·Nature Communications ·Brandon Hadland, Barbara Varnum‐Finney, (unknown), (unknown), (unknown), Adam Heck, (unknown), Dana L. Jackson, Tomer Itkin, Jason M. Butler, Shahin Rafii, Cole Trapnell, Irwin D. Bernstein	28
6	Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate 2021 ·Proceedings of the National Academy of Sciences ·Tyler M. Lu, Sean Houghton, Tarig Magdeldin, José Gabriel Barcia Durán, Andrew P. Minotti, Amanda M. Snead, Andrew A. Sproul, Duc-Huy T. Nguyen, Jenny Xiang, Howard A. Fine, Zev Rosenwaks, Lorenz Studer, Shahin Rafii, Dritan Agalliu, David Redmond, Raphaël Lis	146
7	Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice 2021 ·Communications Biology ·José Gabriel Barcia Durán, Tyler M. Lu, Sean Houghton, Fuqiang Geng, Ryan Schreiner, Jenny Xiang, Shahin Rafii, David Redmond, Raphaël Lis	10
8	Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes 2021 ·Genes & Development ·Elizabeth D. Howell, Amanda D. Yzaguirre, Peng Gao, Raphaël Lis, Bing He, Melike Lakadamyali, Shahin Rafii, Kai Tan, Nancy A. Speck	15
9	Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors 2020 ·Blood ·Silvana Di Giandomenico, Pouneh Kermani, (unknown), (unknown), Ghaith Abu‐Zeinah, Thomas W. Stephens, (unknown), Ryan Schreiner, Fabienne Brenet, Shahin Rafii, Joseph M. Scandura	11
10	Molecular determinants of nephron vascular specialization in the kidney 2019 ·Nature Communications ·David M. Barry, Elizabeth A. McMillan, Balvir Kunar, Raphaël Lis, Tuo Zhang, Tyler M. Lu, Edward Daniel, Masataka Yokoyama, Jesús M. Gómez-Salinero, Angara Sureshbabu, Ondine Cleaver, Annarita Di Lorenzo, Mary E. Choi, Jenny Xiang, David Redmond, Sina Y. Rabbany, Thangamani Muthukumar, Shahin Rafii	80
11	Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells 2015 ·Journal of Clinical Investigation ·Jennifer L. Gori, Jason M. Butler, (unknown), (unknown), Michael G. Poulos, Michael Ginsberg, Daniel J. Nolan, Olivier Elemento, Brent L. Wood, Jennifer E. Adair, Shahin Rafii, (unknown)	89
12	Akt-Activated Endothelium Constitutes the Niche for Residual Disease and Resistance to Bevacizumab in Ovarian Cancer 2014 ·Molecular Cancer Therapeutics ·Bella S. Guerrouahen, Jennifer Pasquier, (unknown), Mahtab Maleki, (unknown), Amber Yasmeen, Pegah Ghiabi, Raphaël Lis, Fabien Vidal, Ayman Saleh, Walter H. Gotlieb, Shahin Rafii, Arash Rafii	30
13	Retinal angiogenesis suppression through small molecule activation of p53 2013 ·Journal of Clinical Investigation ·Sai H. Chavala, Younghee Kim, Laura Tudisco, Valeria Cicatiello, Till Milde, Nagaraj Kerur, (unknown), Susan E. Yanni, Victor H. Guaiquil, William W. Hauswirth, John S. Penn, Shahin Rafii, Sandro De Falco, Thomas C. M. Lee, Jayakrishna Ambati	24
14	Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition 2012 ·Cancer Research ·Dingcheng Gao, Natasha Joshi, Hyejin Choi, Seongho Ryu, Mary Hahn, Raúl Catena, Helen Sadik, Pedram Argani, Patrick Wagner, Linda T. Vahdat, Jeffrey L. Port, Brendon M. Stiles, Saraswati Sukumar, Nasser K. Altorki, Shahin Rafii, Vivek Mittal	234
15	Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization 2006 ·Journal of Clinical Investigation ·Hans‐Georg Kopp, Andrea T. Hooper, M. Johan Broekman, Scott T. Avecilla, Isabelle Petit, Min Luo, Till Milde, Carlos A. Ramos, Fan Zhang, (unknown), Paul Börnstein, David Jin, Aaron J. Marcus, Shahin Rafii	80
16	Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors 2005 ·Journal of Clinical Investigation ·Pouneh Kermani, (unknown), David Jin, (unknown), Wendy Schaffer, Anne Chiang, Loı̈c Vincent, Matthias Friedrich, Koji Shido, Neil R. Hackett, Ronald G. Crystal, Shahin Rafii, Barbara L. Hempstead	74
17	Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors 2005 ·Journal of Clinical Investigation ·Pouneh Kermani, (unknown), David Jin, (unknown), Wendy Schaffer, Anne Chiang, Loı̈c Vincent, Matthias Friedrich, Koji Shido, Neil R. Hackett, Ronald G. Crystal, Shahin Rafii, Barbara L. Hempstead	200
18	Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis breakdown → 2003 ·Science ·Mónica Garcı́a-Barros, François Paris, Carlos Cordon‐Cardo, David Lyden, Shahin Rafii, Adriana Haimovitz‐Friedman, Zvi Fuks, Richard Kolesnick	1232
19	Ex vivo Expansion of Stem and Progenitor Cells in Co-culture of Mobilized Peripheral Blood CD34 ⁺ Cells on Human Endothelium Transfected with Adenovectors Expressing Thrombopoietin, c-kit Ligand, and Flt-3 Ligand 2002 ·Journal of Hematotherapy & Stem Cell Research ·Pierre Feugier, Deog Yeon Jo, (unknown), Karen L. MacKenzie, Shahin Rafii, Ronald G. Crystal, Malcolm A.S. Moore	21
20	The Effects of Flk-2/flt3 Ligand as Compared with c-kit Ligand on Short-Term and Long-Term Proliferation of CD34+ Hematopoietic Progenitors Elicited from Human Fetal Liver, Umbilical Cord Blood, Bone Marrow, and Mobilized Peripheral Blood 1996 ·Journal of Hematotherapy ·F.L. Shapiro, Bronislaw Pytowski, Shahin Rafii, Luc de Witte, Dan Hicklin, Tzy‐Jyun Yao, M A Moore	17

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