Ophir D. Klein

15.7k total citations · 3 hit papers
210 papers, 10.1k citations indexed

About

Ophir D. Klein is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Ophir D. Klein has authored 210 papers receiving a total of 10.1k indexed citations (citations by other indexed papers that have themselves been cited), including 139 papers in Molecular Biology, 56 papers in Genetics and 38 papers in Oncology. Recurrent topics in Ophir D. Klein's work include dental development and anomalies (74 papers), Cancer Cells and Metastasis (34 papers) and Oral and Maxillofacial Pathology (27 papers). Ophir D. Klein is often cited by papers focused on dental development and anomalies (74 papers), Cancer Cells and Metastasis (34 papers) and Oral and Maxillofacial Pathology (27 papers). Ophir D. Klein collaborates with scholars based in United States, Canada and China. Ophir D. Klein's co-authors include Frédéric J. de Sauvage, Gail R. Martin, Brian Biehs, Kerstin Seidel, Hua Tian, Mark A. Krasnow, Ross J. Metzger, Søren Warming, Linda Rangell and Kevin G. Leong and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ophir D. Klein

200 papers receiving 10.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

2011 904 citations Ophir D. Klein, Frédéric J. de Sauvage et al. Nature profile →
In vitro generation of human pluripotent stem cell derived lung organoids

2015 612 citations Ophir D. Klein et al. profile →
The branching programme of mouse lung development

2008 578 citations Ophir D. Klein et al. Nature profile →

Peers

Countries citing papers authored by Ophir D. Klein

Since Specialization

Citations

This map shows the geographic impact of Ophir D. Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ophir D. Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ophir D. Klein more than expected).

Fields of papers citing papers by Ophir D. Klein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ophir D. Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ophir D. Klein. The network helps show where Ophir D. Klein may publish in the future.

Co-authorship network of co-authors of Ophir D. Klein

This figure shows the co-authorship network connecting the top 25 collaborators of Ophir D. Klein. A scholar is included among the top collaborators of Ophir D. Klein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ophir D. Klein. Ophir D. Klein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Decoding epithelial regeneration in the cornea: multi-omic analysis reveals cellular plasticity as central mechanism 2025 ·Cellular & Molecular Biology Letters ·(unknown), (unknown), (unknown), Pauline Marangoni, (unknown), Sílvia Llorens, (unknown), (unknown), Eric Jacquet, Jérôme Vialaret, Vincent Daïen, Alexandre David, Christophe Hirtz, Karine Loulier, Ophir D. Klein, Frédéric Michon	0
2	Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair 2025 ·Science Translational Medicine ·Michelle Griffin, (unknown), (unknown), Dario Boffelli, (unknown), (unknown), Nicholas Guardino, Jason Guo, Jennifer Parker, Michael Januszyk, C. Alexander Valencia, (unknown), John Lu, Rachel K. Zwick, Derrick C. Wan, Ophir D. Klein, Michael T. Longaker	0
3	A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder 2024 ·IEEE Access ·(unknown), (unknown), Harold Matthews, (unknown), (unknown), Meng Yuan, Giorgos Bouritsas, Gareth Baynam, Peter Hammond, Richard A. Spritz, Ophir D. Klein, Michael M. Bronstein, Benedikt Hallgrímsson, Hilde Peeters, Peter Claes	0
4	Harnessing synthetic biology to engineer organoids and tissues 2023 ·Cell stem cell ·Coralie Trentesaux, Toshimichi Yamada, Ophir D. Klein, Wendell A. Lim	36
5	SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline 2023 ·Biology of Reproduction ·(unknown), Makiko Yamada, Thierry N’Tumba-Byn, (unknown), Meng Gao, Yang Hu, Pauline Marangoni, Ying Liu, Todd Evans, Shahin Rafii, Ophir D. Klein, Henning U. Voss, Anna‐Katerina Hadjantonakis, Olivier Elemento, L. A. Martin, Marco Seandel	3
6	Intracellular pH dynamics regulates intestinal stem cell lineage specification 2023 ·Nature Communications ·(unknown), (unknown), David Castillo‐Azofeifa, Ophir D. Klein, Todd Nystul, Diane L. Barber	13
7	Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral 2023 ·International Journal of Oral Science ·Hyun‐Yi Kim, (unknown), Eun‐Jung Kim, (unknown), Jong‐Min Lee, (unknown), Wenjun Liu, Ophir D. Klein, Derk Joester, Han‐Sung Jung	11
8	Programming multicellular assembly with synthetic cell adhesion molecules 2022 ·Nature ·Adam J. Stevens, Andrew R. Harris, (unknown), Ki H. Kim, Coralie Trentesaux, (unknown), Wesley L. McKeithan, Faranak Fattahi, Ophir D. Klein, Daniel A. Fletcher, Wendell A. Lim	96
9	A Deep Invertible 3-D Facial Shape Model for Interpretable Genetic Syndrome Diagnosis 2022 ·IEEE Journal of Biomedical and Health Informatics ·Jordan J. Bannister, Matthias Wilms, J. David Aponte, David C. Katz, Ophir D. Klein, François P. Bernier, Richard A. Spritz, Benedikt Hallgrímsson, Nils D. Forkert	11
10	Application of full-genome analysis to diagnose rare monogenic disorders 2021 ·npj Genomic Medicine ·Joseph T.C. Shieh, (unknown), K. Wong, Michal Levy‐Sakin, Michelle Verghese, Anne Slavotinek, Renata C. Gallagher, Bryce A. Mendelsohn, (unknown), Daniah Beleford, Hazel Perry, (unknown), Andrew G. Sharo, Steven E. Brenner, Zhongxia Qi, Jingwei Yu, Ophir D. Klein, David I. K. Martin, Pui–Yan Kwok, Dario Boffelli	29
11	Inflation-collapse dynamics drive patterning and morphogenesis in intestinal organoids 2021 ·Cell stem cell ·Naren Tallapragada, (unknown), Tomáš Wald, (unknown), (unknown), Ophir D. Klein, Allon M. Klein	55
12	Fully Automatic Landmarking of Syndromic 3D Facial Surface Scans Using 2D Images 2020 ·Sensors ·Jordan J. Bannister, (unknown), J. David Aponte, David C. Katz, Matthias Wilms, Ophir D. Klein, François P. Bernier, Richard A. Spritz, Benedikt Hallgrímsson, Nils D. Forkert	19
13	Engineering synthetic morphogen systems that can program multicellular patterning 2020 ·Science ·Satoshi Toda, Wesley L. McKeithan, Teemu J. Häkkinen, Maria del Pilar Lopez Pazmino, Ophir D. Klein, Wendell A. Lim	89
14	KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice 2020 ·JCI Insight ·Jasmine C. Wong, Pedro A. Pérez–Mancera, (unknown), (unknown), Joaquím Grego‐Bessa, (unknown), Scott C. Kogan, Amnon Sharir, (unknown), (unknown), Denny Schanze, Pau Castel, K. Hirose, Guo N. Huang, Martin Zenker, Dean Sheppard, Ophir D. Klein, David A. Tuveson, Benjamin S. Braun, Kevin Shannon	8
15	Lgr5+ telocytes are a signaling source at the intestinal villus tip 2020 ·Nature Communications ·Keren Bahar Halpern, Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo‐Azofeifa, Milena Rozenberg, Lydia Farack, Adi Egozi, (unknown), Inna Averbukh, Yotam Harnik, Noa Weinberg-Corem, Frédéric J. de Sauvage, Ido Amit, Ophir D. Klein, Michal Shoshkes-Carmel, Shalev Itzkovitz	100
16	YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate 2020 ·Journal of Dental Research ·Alice F. Goodwin, (unknown), Nguyen T. K. Vo, Jeffrey O. Bush, Ophir D. Klein	18
17	SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis 2018 ·Development ·David Castillo‐Azofeifa, Kerstin Seidel, (unknown), Erin Golden, (unknown), Ophir D. Klein, Linda A. Barlow	21
18	Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor 2017 ·Development ·(unknown), Kerstin Seidel, Zhao Sun, (unknown), Brad A. Amendt, Ophir D. Klein, Frédéric Michon	25
19	The WNT10A gene in ectodermal dysplasias and selective tooth agenesis 2014 ·American Journal of Medical Genetics Part A ·Gabriele Mues, (unknown), (unknown), Alexandre R. Vieira, Figen Seymen, Ophir D. Klein, Rena N. D’Souza	38
20	Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation 2013 ·Human Molecular Genetics ·Alice F. Goodwin, William E. Tidyman, Andrew H. Jheon, Amnon Sharir, Xu Zheng, Cyril Charles, James A. Fagin, Martin McMahon, Thomas G.H. Diekwisch, Bernhard Ganss, Katherine A. Rauen, Ophir D. Klein	30

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact