Karen L. MacKenzie

4.7k citations

68 papers · 2.4k indexed · h-index 29

Hematology top 2%
- Acute Myeloid Leukemia Research 15
- Chronic Myeloid Leukemia Treatments 7
- Hematopoietic Stem Cell Transplantation 5
Genetics top 5%
- Virus-based gene therapy research 6
Aging top 10%
Oncology top 5%
- Cancer-related Molecular Pathways 7
Molecular Biology top 5%
- RNA Interference and Gene Delivery 4
Physiology
- Telomeres, Telomerase, and Senescence 17
Public Health, Environmental and Occupational Health
- Acute Lymphoblastic Leukemia research 8

Co-authors: Malcolm A.S. Moore Richard B. Lock Greg M. Arndt Kacper Jankowski Michel Sadelain Murray D. Norris George A. Wolff Michelle Haber
Cited by: Hematology Genetics Aging
Partner nations: Australia United States United Kingdom

In The Last Decade

Karen L. MacKenzie

68 papers receiving 2.4k citations

Peers

Countries citing papers authored by Karen L. MacKenzie

Since Specialization

Citations

This map shows the geographic impact of Karen L. MacKenzie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen L. MacKenzie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen L. MacKenzie more than expected).

Fields of papers citing papers by Karen L. MacKenzie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen L. MacKenzie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen L. MacKenzie. The network helps show where Karen L. MacKenzie may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Karen L. MacKenzie, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karen L. MacKenzie Line = papers co-authored together Karen L. MacKenzie links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma Ashleigh M. Fordham,Jinhan Xie,Andrew J. Gifford,Carol Wadham,Lisa T. Morgan,Emily Mould,Mitali Fadia,Lei Zhai,Hassina Massudi,Zara Ali,Glenn M. Marshall,Robyn Lukeis,Jamie I. Fletcher,Karen L. MacKenzie,Toby N. Trahair	2020	21
2	DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts Laura Richards,Ashu Kumari,Kathy Knezevic,Julie A.I. Thoms,Georg von Jonquières,Christine E. Napier,Zara Ali,Rosemary O’Brien,Jonathon Marks-Bluth,Michelle F. Maritz,Hilda A. Pickett,Jonathan Morris,John E. Pimanda,Karen L. MacKenzie	2019	22
3	Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols Susan Corley,Karen L. MacKenzie,Annemiek Beverdam,Louise F. Roddam,Marc R. Wilkins	2017	27
4	MYC -Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin Rosemary O’Brien,Sieu L. Tran,Michelle F. Maritz,Bing Liu,Cheng Kong,Stefania Purgato,Chen Yang,Jayne Murray,Amanda J. Russell,Claudia L. Flemming,Georg von Jonquières,Hilda A. Pickett,Wendy B. London,Michelle Haber,Preethi H. Gunaratne,Murray D. Norris,Giovanni Perini,Jamie I. Fletcher,Karen L. MacKenzie	2016	36
5	A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of anERG-driven transcriptional network Ashwin Unnikrishnan,Yi Fang Guan,Yizhou Huang,Dominik Beck,Julie A.I. Thoms,Sofie Peirs,Kathy Knezevic,Shiyong Ma,Inge Van de Walle,Ineke de Jong,Zara Ali,Ling Zhong,Mark J. Raftery,Tom Taghon,Jonas Larsson,Karen L. MacKenzie,Pieter Van Vlierberghe,Jason W.H. Wong,John E. Pimanda	2016	16
6	Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study Eddy Pasquier,Nicolás André,Janine Street,Anuradha Chougule,Bharat Rekhi,Jaya Ghosh,Deepa Susan Joy Philip,Marie Meurer,Karen L. MacKenzie,Maria Kavallaris,Shripad Banavali	2016	86
7	Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias Melinda L. Tursky,Dominik Beck,Julie A.I. Thoms,Yizhou Huang,Anupriya Kumari,Ashwin Unnikrishnan,Kathy Knezevic,Kathryn Evans,(unknown),Eunhee Lee,Jonathan Morris,Lior Goldberg,Shai Izraeli,Jason W.H. Wong,Jake Olivier,Richard B. Lock,Karen L. MacKenzie,John E. Pimanda	2014	17
8	Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells Eddy Pasquier,Maria‐Pia Tuset,Janine Street,Snega Sinnappan,Karen L. MacKenzie,Diane Braguer,Nicolás André,Maria Kavallaris	2012	47
9	Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16INK4a during immortalization C-Y Kan,Victoria W. Wen,Eddy Pasquier,Kacper Jankowski,Melissa H. Chang,(unknown),Maria Kavallaris,Karen L. MacKenzie	2012	11
10	Induction of Vascular Endothelial Growth Factor Secretion by Childhood Acute Lymphoblastic Leukemia Cells via the FLT-3 Signaling Pathway Ana Marković,Karen L. MacKenzie,Richard B. Lock	2011	12
11	Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells Christine E. Napier,Laura A. Veas,Chin-Yi Kan,Lisa Taylor,Jun Yuan,Victoria W. Wen,Alexander C. James,Tracey O’Brien,Richard B. Lock,Karen L. MacKenzie	2010	16
12	Inactivation of Myocardin and p16 during Malignant Transformation Contributes to a Differentiation Defect Michael Milyavsky,Igor Shats,Alina Cholostoy,Ran Brosh,Yosef Buganim,Lilach Weisz,Ira Kogan,Merav Cohen,Maria Shatz,Shalom Madar,Eyal Kalo,Naomi Goldfinger,Jun Yuan,Shulamit Ron,Karen L. MacKenzie,Amir Eden,Varda Rotter	2007	61
13	Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo Lara Perryman,Julie M. Blair,Elizabeth A. Kingsley,Bożena Szymańska,Kim Ow,Victoria W. Wen,Karen L. MacKenzie,Peter Vermeulen,P. Jackson,Pamela J. Russell	2006	12
14	Osteopetrotic Mouse Stroma with Thrombopoietin, c-kit Ligand, and flk-2 Ligand Supports Long-Term Mobilized CD34 ⁺ Hematopoiesis In Vitro Pierre Feugier,Na Li,Deog‐Yeon Jo,Jae Hung Shieh,Karen L. MacKenzie,Jean‐François Lesesve,Véronique Latger‐Cannard,Danièle Bensoussan,Ronald G. Crystal,Shahin Rafii,J F Stoltz,Malcolm A.S. Moore	2005	20
15	FLT-3: a new focus in the understanding of acute leukemia Ana Marković,Karen L. MacKenzie,Richard B. Lock	2005	51
16	Mutant N-ras preferentially drives human CD34+ hematopoietic progenitor cells into myeloid differentiation and proliferation both in vitro and in the NOD/SCID mouse Sylvie Shen,Alla Dolnikov,Toby Passioura,Michelle Millington,Simon Wotherspoon,Alison Rice,Karen L. MacKenzie,Geoff Symonds	2004	23
17	Ex vivo Expansion of Stem and Progenitor Cells in Co-culture of Mobilized Peripheral Blood CD34 ⁺ Cells on Human Endothelium Transfected with Adenovectors Expressing Thrombopoietin, c-kit Ligand, and Flt-3 Ligand Pierre Feugier,Deog Yeon Jo,Jae Hung Shieh,Karen L. MacKenzie,Shahin Rafii,Ronald G. Crystal,Malcolm A.S. Moore	2002	21
18	Methotrexate selection of long-term culture initiating cells following transduction of CD34+ cells with a retrovirus containing a mutated human dihydrofolate reductase gene Naoko Takebe,Licheng Xu,Karen L. MacKenzie,Joseph R. Bertino,Malcolm A.S. Moore	2002	9
19	Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras Karen L. MacKenzie,Sonia Franco,Afzal J. Naiyer,Chad May,Michel Sadelain,Shahin Rafii,Malcolm A.S. Moore	2002	56
20	Optimizing Conditions for Gene Transfer into Human Hematopoietic Cells Malcolm A.S. Moore,Karen L. MacKenzie	1999	5

About Karen L. MacKenzie

Karen L. MacKenzie is a scholar working on Aging, Hematology and Oncology, having authored 68 papers that have together received 2.4k indexed citations. Recurring topics across this work include Telomeres, Telomerase, and Senescence (17 papers), Acute Myeloid Leukemia Research (15 papers), Acute Lymphoblastic Leukemia research (8 papers), Cancer-related Molecular Pathways (7 papers), Chronic Myeloid Leukemia Treatments (7 papers), Virus-based gene therapy research (6 papers), Hematopoietic Stem Cell Transplantation (5 papers) and RNA Interference and Gene Delivery (4 papers). The work is most often cited by research in Hematology (528 citations), Genetics (231 citations) and Aging (37 citations). Karen L. MacKenzie has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Malcolm A.S. Moore, Richard B. Lock, Greg M. Arndt, Kacper Jankowski, Michel Sadelain, Murray D. Norris, George A. Wolff, Michelle Haber, Chad May and Jörg Cammenga.

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