Scott I. Klein

607 citations

19 papers · 507 indexed · h-index 14

Molecular Biology
Organic Chemistry top 10%
Hematology top 10%
Computational Theory and Mathematics top 10%
Cardiology and Cardiovascular Medicine

Co-authors: I. Danishefsky Alfred P. Spada Valeria Chu Henry W. Pauls J.P. Guilloteau Robert J. Leadley S. Maignan Uttam Pati
Topics: Blood Coagulation and Thrombosis Mechanisms (8 papers)Coagulation, Bradykinin, Polyphosphates, and Angioedema (4 papers)Antiplatelet Therapy and Cardiovascular Diseases (3 papers)
Cited by: Hematology Internal Medicine Organic Chemistry
Journals: Journal of the American Chemical Society Journal of Medicinal Chemistry The Journal of Organic Chemistry
Partner nations: United States Switzerland

In The Last Decade

Scott I. Klein

19 papers receiving 475 citations

Peers

Countries citing papers authored by Scott I. Klein

Since Specialization

Citations

This map shows the geographic impact of Scott I. Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Scott I. Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Scott I. Klein more than expected).

Fields of papers citing papers by Scott I. Klein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Scott I. Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Scott I. Klein. The network helps show where Scott I. Klein may publish in the future.

Co-authorship network of co-authors of Scott I. Klein

This figure shows the co-authorship network connecting the top 25 collaborators of Scott I. Klein. A scholar is included among the top collaborators of Scott I. Klein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Scott I. Klein. Scott I. Klein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	A novel series of potent and selective small molecule inhibitors of the complement component C1s 2004 ·Bioorganic & Medicinal Chemistry Letters ·Nalin L. Subasinghe,(unknown),Carl R. Illig,Matthias Rudolph,Scott I. Klein,Ehab M. Khalil,Richard Söll,Roger Bone,John Spurlino,Renée L. DesJarlais,Carl Crysler,Maxwell D. Cummings,Philip E. Morris,John Michael Kilpatrick,Y. Sudhakara Babu	18
2	Optimization of the β-Aminoester class of factor Xa inhibitors. part 1: P4 and side-Chain modifications for improved In vitro potency 2002 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Scott I. Klein,Kevin R. Guertin,(unknown),Allison L. Zulli,Henry W. Pauls,Alfred P. Spada,Daniel L. Cheney,Karen Brown,Dennis Colussi,Valeria Chu,Robert J. Leadley,Christopher T. Dunwiddie	14
3	Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity 2002 ·Bioorganic & Medicinal Chemistry Letters ·Kevin R. Guertin,(unknown),Scott I. Klein,Allison L. Zulli,(unknown),Yong Gong,Alfred P. Spada,Daniel L. Cheney,(unknown),J.P. Guilloteau,Karen Brown,Dennis Colussi,Valeria Chu,Christopher L. Heran,(unknown),Ross Bentley,Christopher T. Dunwiddie,Robert J. Leadley,Henry W. Pauls	45
4	Superiority of Enoxaparin Over Heparin in Combination With a GPIIb/IIIa Receptor Antagonist During Coronary Thrombolysis in Dogs 2001 ·Thrombosis Research ·Sam Rebello,Charles Kasiewski,Ross Bentley,(unknown),Valeria Chu,Jeffrey S. Bostwick,Scott I. Klein,Mark H. Perrone,Robert J. Leadley	13
5	Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis 2000 ·European Journal of Pharmacology ·Christopher L. Heran,(unknown),Charles Kasiewski,Jeffrey S. Bostwick,Ross Bentley,Scott I. Klein,Valeria Chu,Karen Brown,Dennis Colussi,(unknown),Mark H. Perrone,Robert J. Leadley	23
6	Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors 2000 ·Journal of Medicinal Chemistry ·S. Maignan,J.P. Guilloteau,Stéphanie Pouzieux,Yong Mi Choi-Sledeski,Michael R. Becker,Scott I. Klein,William R. Ewing,Henry W. Pauls,Alfred P. Spada,Vincent Mikol	116
7	Design of a New Class of Orally Active Fibrinogen Receptor Antagonists 1998 ·Journal of Medicinal Chemistry ·Scott I. Klein,Bruce F. Molino,(unknown),(unknown),Valeria Chu,Karen Brown,Ralph D. Sabatino,Jeffrey S. Bostwick,Charles Kasiewski,Ross Bentley,(unknown),Mark H. Perrone,Christopher T. Dunwiddie,Robert J. Leadley	15
8	Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa 1998 ·Journal of Medicinal Chemistry ·Scott I. Klein,(unknown),(unknown),Kevin R. Guertin,Daniel L. Cheney,Alfred P. Spada,(unknown),Karen Brown,Dennis Colussi,Christopher L. Heran,(unknown),Robert J. Leadley,Christopher T. Dunwiddie,Mark H. Perrone,Valeria Chu	35
9	Constrained β-alanine based GpIIb/IIIa antagonists 1997 ·Bioorganic & Medicinal Chemistry Letters ·Scott I. Klein,(unknown),Bruce F. Molino,Valeria Chu	18
10	Non-peptide fibrinogen receptor antagonists based upon a 4-substituted piperidine scaffold 1996 ·Bioorganic & Medicinal Chemistry Letters ·Scott I. Klein,Bruce F. Molino,(unknown),(unknown),Robert J. Leadley,Ralph D. Sabatino,Christopher T. Dunwiddie,Valeria Chu	3
11	Anti-thrombotic activity of RG13965, a novel platelet fibrinogen receptor antagonist 1996 ·Thrombosis Research ·Jeffrey S. Bostwick,Charles Kasiewski,Valeria Chu,Scott I. Klein,Ralph D. Sabatino,Mark H. Perrone,Christopher T. Dunwiddie,Jacquelynn J. Cook,Robert J. Leadley	8
12	O-benzyl hydroxyproline as a bioisostere for Phe-Pro: Novel dipeptide thrombin inhibitors 1996 ·Bioorganic & Medicinal Chemistry Letters ·Scott I. Klein,Jeffrey M. Dener,Bruce F. Molino,(unknown),(unknown),Christopher T. Dunwiddie,Charles Kasiewski,Robert J. Leadley	10
13	Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides 1992 ·Journal of Medicinal Chemistry ·Raymond D. Youssefyeh,(unknown),(unknown),Scott I. Klein,(unknown),(unknown),Richard M. Woodward,(unknown),(unknown)	20
14	Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides 1992 ·Journal of Medicinal Chemistry ·Raymond D. Youssefyeh,(unknown),Scott I. Klein,(unknown),(unknown),(unknown),(unknown),Kent Neuenschwander,Leo R. Fitzpatrick	20
15	5051405 Anti-thrombotic peptides and pseudopeptides 1992 ·Transfusion Science ·Scott I. Klein,Bruce F. Molino,(unknown),(unknown)	1
16	Practical routes to two functionalized decalones for the synthesis of quassinoids 1986 ·The Journal of Organic Chemistry ·Frederick E. Ziegler,(unknown),John F. Kadow,Scott I. Klein,Uttam Pati,(unknown)	20
17	Acyclic diastereoselection as a synthetic route to quassinoids: a Claisen rearrangement based strategy for bruceantin 1985 ·Journal of the American Chemical Society ·Frederick E. Ziegler,Scott I. Klein,Uttam Pati,(unknown)	35
18	Effect of heparin modification on its activity in enhancing the inhibition of thrombin by antithrombin III 1977 ·Biochimica et Biophysica Acta (BBA) - General Subjects ·I. Danishefsky,(unknown),Scott I. Klein	39
19	Synthesis of heparin-sepharoses and their binding with thrombin and antithrombin-heparin cofactor 1976 ·Thrombosis Research ·I. Danishefsky,(unknown),(unknown),Scott I. Klein	54

About Scott I. Klein

Scott I. Klein is a scholar working on Hematology, Internal Medicine and Immunology and Allergy, having authored 19 papers that have together received 507 indexed citations. Recurring topics across this work include Blood Coagulation and Thrombosis Mechanisms (8 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (4 papers) and Antiplatelet Therapy and Cardiovascular Diseases (3 papers). The work is most often cited by research in Hematology (122 citations), Internal Medicine (25 citations) and Organic Chemistry (161 citations). Scott I. Klein has collaborated with scholars based in United States and Switzerland. Frequent co-authors include I. Danishefsky, Alfred P. Spada, Valeria Chu, Henry W. Pauls, J.P. Guilloteau, Robert J. Leadley, S. Maignan, Uttam Pati, Michael R. Becker and Yong Mi Choi-Sledeski. Their work appears in journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

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