Scott A. Oakes

11.6k total citations · 8 hit papers
47 papers, 8.7k citations indexed

About

Scott A. Oakes is a scholar working on Molecular Biology, Cell Biology and Epidemiology. According to data from OpenAlex, Scott A. Oakes has authored 47 papers receiving a total of 8.7k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Molecular Biology, 22 papers in Cell Biology and 20 papers in Epidemiology. Recurrent topics in Scott A. Oakes's work include Endoplasmic Reticulum Stress and Disease (21 papers), Autophagy in Disease and Therapy (17 papers) and Cell death mechanisms and regulation (9 papers). Scott A. Oakes is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (21 papers), Autophagy in Disease and Therapy (17 papers) and Cell death mechanisms and regulation (9 papers). Scott A. Oakes collaborates with scholars based in United States, Italy and Australia. Scott A. Oakes's co-authors include Feroz R. Papa, Stanley J. Korsmeyer, Luca Scorrano, Tullio Pozzan, Joseph T. Opferman, Claudio Hetz, Éric Chevet, Emily H. Cheng, John-Paul Upton and Dan Han and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Scott A. Oakes

46 papers receiving 8.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Role of Endoplasmic Reticulum Stress in Human Pathology

2014 1.2k citations Scott A. Oakes, Feroz R. Papa profile →
BAX and BAK Regulation of Endoplasmic Reticulum Ca ²⁺ : A Control Point for Apoptosis

2003 1.2k citations Luca Scorrano, Scott A. Oakes et al. Science profile →
A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

2002 890 citations Luca Scorrano, Scott A. Oakes et al. Developmental Cell profile →
IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

2012 696 citations Alana G. Lerner, Paurush Praveen et al. Cell Metabolism profile →
IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

2009 654 citations Dan Han, Alana G. Lerner et al. Cell profile →
Proteostasis control by the unfolded protein response

2015 563 citations Scott A. Oakes et al. Nature Cell Biology profile →
IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

2012 532 citations John-Paul Upton, Likun Wang et al. Science profile →
Endoplasmic Reticulum Stress Signaling in Cancer Cells

2020 266 citations Scott A. Oakes profile →

Peers

Countries citing papers authored by Scott A. Oakes

Since Specialization

Citations

This map shows the geographic impact of Scott A. Oakes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Scott A. Oakes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Scott A. Oakes more than expected).

Fields of papers citing papers by Scott A. Oakes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Scott A. Oakes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Scott A. Oakes. The network helps show where Scott A. Oakes may publish in the future.

Co-authorship network of co-authors of Scott A. Oakes

This figure shows the co-authorship network connecting the top 25 collaborators of Scott A. Oakes. A scholar is included among the top collaborators of Scott A. Oakes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Scott A. Oakes. Scott A. Oakes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Dissecting tumor transcriptional heterogeneity from single-cell RNA-seq data by generalized binary covariance decomposition 2025 ·Nature Genetics ·(unknown), Peter Carbonetto, (unknown), Scott A. Oakes, Kay F. Macleod, Matthew Stephens	3
2	Unfolding emergency calls stress granules to the ER 2024 ·Nature Cell Biology ·David Pincus, Scott A. Oakes	1
3	The Integrated Stress Response in Pancreatic Development, Tissue Homeostasis, and Cancer 2024 ·Gastroenterology ·Greg Malnassy, (unknown), Kay F. Macleod, Scott A. Oakes	4
4	Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration 2023 ·Investigative Ophthalmology & Visual Science ·Dawiyat Massoudi, Sean P. Gorman, Yien–Ming Kuo, Takao Iwawaki, Scott A. Oakes, Feroz R. Papa, Douglas B. Gould	6
5	Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival 2019 ·Cancer Research ·(unknown), (unknown), Maike Thamsen, Rajarshi Ghosh, Justin Peng, Micah J. Gliedt, Rosa Meza-Acevedo, (unknown), Annie Hiniker, Grace Kim, Dustin J. Maly, Bradley J. Backes, Feroz R. Papa, Scott A. Oakes	25
6	Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation 2015 ·Current Biology ·(unknown), (unknown), Collin Melton, Noelle E. Huskey, Olga Momčilović, Andrei Goga, Robert Blelloch, Scott A. Oakes	16
7	Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients 2014 ·Proceedings of the National Academy of Sciences ·Courtney A. Crane, Kathryn Austgen, Kristen Haberthur, (unknown), Kara White Moyes, Lia Avanesyan, Lawrence Fong, Michael J. Campbell, Stewart Cooper, Scott A. Oakes, Andrew T. Parsa, Lewis L. Lanier	144
8	Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons 2014 ·Acta Neuropathologica Communications ·(unknown), Marijn Kuijpers, Elize D. Haasdijk, Eva Teuling, Scott A. Oakes, Casper C. Hoogenraad, Dick Jaarsma	48
9	IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2 breakdown → 2012 ·Science ·John-Paul Upton, Likun Wang, Dan Han, (unknown), Noelle E. Huskey, Lionel Lim, Morgan Truitt, Michael T. McManus, Davide Ruggero, Andrei Goga, Feroz R. Papa, Scott A. Oakes	532
10	IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress breakdown → 2012 ·Cell Metabolism ·Alana G. Lerner, (unknown), Paurush Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, (unknown), Vinh Nguyen, Bradley J. Backes, Myriam Heiman, Nathaniel Heintz, Paul Greengard, Simon T. Hui, Qizhi Tang, Ala Trusina, Scott A. Oakes, Feroz R. Papa	696
11	The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress 2011 ·Nature Cell Biology ·Kathryn Austgen, (unknown), Tae‐Ju Park, Tom Curran, Scott A. Oakes	25
12	Signaling cell death from the endoplasmic reticulum stress response 2010 ·Current Opinion in Cell Biology ·Gordon C. Shore, Feroz R. Papa, Scott A. Oakes	326
13	IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates breakdown → 2009 ·Cell ·Dan Han, Alana G. Lerner, Lieselotte Vande Walle, John-Paul Upton, Weihong Xu, Andrew Hagen, Bradley J. Backes, Scott A. Oakes, Feroz R. Papa	654
14	A kinase inhibitor activates the IRE1α RNase to confer cytoprotection against ER stress 2007 ·Biochemical and Biophysical Research Communications ·Dan Han, John-Paul Upton, Andrew Hagen, (unknown), Scott A. Oakes, Feroz R. Papa	43
15	The Control of Endoplasmic Reticulum-Initiated Apoptosis by the BCL-2 Family of Proteins 2006 ·Current Molecular Medicine ·Scott A. Oakes, Stephen Lin, Michael C. Bassik	83
16	Untangling the Web 2004 ·Developmental Cell ·Scott A. Oakes, Stanley J. Korsmeyer	18
17	Regulation of endoplasmic reticulum Ca2+ dynamics by proapoptotic BCL-2 family members 2003 ·Biochemical Pharmacology ·Scott A. Oakes, Joseph T. Opferman, Tullio Pozzan, Stanley J. Korsmeyer, Luca Scorrano	97
18	KNEE EXERCISE CLASSES ARE SUPERIOR TO HOME EXERCISES IN REDUCING PAIN AND INCREASING FUNCTION IN PATIENTS WITH KNEE OSTEOARTHRITIS: RESULTS FROM A RANDOMISED CLINICAL TRIAL 2002 ·Lara D. Veeken ·Nicola Goodson, Dorothy J Pattison, Mark Lunt, Robert Luben, Scott A. Oakes, (unknown), Angela Welch, (unknown), A J Silman, (unknown)	3
19	Interleukin-4 Signaling in B Lymphocytes from Patients with X-linked Severe Combined Immunodeficiency 1997 ·Journal of Biological Chemistry ·Naomi Taylor, Fabio Candotti, Susan M. Smith, Scott A. Oakes, Thomas Jähn, (unknown), Jennifer M. Puck, John J. O'Shea, Kenneth I. Weinberg, (unknown)	24
20	Interleukins 2, 4, 7, and 15 Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrates 1 and 2 in T Cells POTENTIAL ROLE OF JAK KINASES 1995 ·Journal of Biological Chemistry ·James A. Johnston, Ling-Mei Wang, Eric P. Hanson, Xiao‐Jian Sun, Morris F. White, Scott A. Oakes, Jacalyn H. Pierce, John J. O’Shea	120

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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