Joseph T. Opferman

12.7k total citations · 3 hit papers
95 papers, 9.5k citations indexed

About

Joseph T. Opferman is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Joseph T. Opferman has authored 95 papers receiving a total of 9.5k indexed citations (citations by other indexed papers that have themselves been cited), including 69 papers in Molecular Biology, 30 papers in Immunology and 19 papers in Oncology. Recurrent topics in Joseph T. Opferman's work include Cell death mechanisms and regulation (48 papers), RNA Interference and Gene Delivery (13 papers) and Immune Cell Function and Interaction (12 papers). Joseph T. Opferman is often cited by papers focused on Cell death mechanisms and regulation (48 papers), RNA Interference and Gene Delivery (13 papers) and Immune Cell Function and Interaction (12 papers). Joseph T. Opferman collaborates with scholars based in United States, Germany and Canada. Joseph T. Opferman's co-authors include Stanley J. Korsmeyer, Tullio Pozzan, Luca Scorrano, Scott A. Oakes, Emily H. Cheng, Christy C. Ong, Philip G. Ashton‐Rickardt, Anthony Letai, Anisha Kothari and Bertram T. Ober and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Joseph T. Opferman

91 papers receiving 9.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

BAX and BAK Regulation of Endoplasmic Reticulum Ca ²⁺ : A Control Point for Apoptosis

2003 1.2k citations Joseph T. Opferman, Emily H. Cheng et al. Science profile →
NIX is required for programmed mitochondrial clearance during reticulocyte maturation

2007 735 citations Joseph T. Opferman, Paul A. Ney et al. profile →
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1

2003 658 citations Joseph T. Opferman, Christy C. Ong et al. Nature profile →

Peers

Countries citing papers authored by Joseph T. Opferman

Since Specialization

Citations

This map shows the geographic impact of Joseph T. Opferman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph T. Opferman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph T. Opferman more than expected).

Fields of papers citing papers by Joseph T. Opferman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph T. Opferman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph T. Opferman. The network helps show where Joseph T. Opferman may publish in the future.

Co-authorship network of co-authors of Joseph T. Opferman

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph T. Opferman. A scholar is included among the top collaborators of Joseph T. Opferman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph T. Opferman. Joseph T. Opferman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The BCL-2 protein family: from discovery to drug development 2025 ·Cell Death and Differentiation ·Carlo M. Croce, David L. Vaux, Andreas Strasser, Joseph T. Opferman, Peter E. Czabotar, Stephen W. Fesik	5
2	Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1 2024 ·Molecular Cell ·(unknown), Meghan E. Turnis, Christy R. Grace, Xiao Li, (unknown), Yong‐Dong Wang, Haiyan Xu, (unknown), Leslie K. Climer, (unknown), Chi‐Lun Chang, Tudor Moldoveanu, Joseph T. Opferman	23
3	Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction 2023 ·Cell Reports ·Utsarga Adhikary, João A. Paulo, Marina Godes, Shrabasti Roychoudhury, Michelle S. Prew, Yael Ben‐Nun, (unknown), Amit Budhraja, Joseph T. Opferman, Dipanjan Chowdhury, Steven P. Gygi, Loren D. Walensky	9
4	ALL-594 Preclinical Assessment of Dual FLT3 and BCL-2 Inhibition in Lineage Ambiguous Leukemia 2023 ·Clinical Lymphoma Myeloma & Leukemia ·Lindsey E. Montefiori, Ilaria Iacobucci, Amit Budhraja, (unknown), (unknown), (unknown), (unknown), Melissa Johnson, Divyabharathi Chepyala, (unknown), Paul S. Mead, Joseph T. Opferman, Charles G. Mullighan	1
5	Combination of MCL-1 and BCL-2 inhibitors is a promising approach for a host-directed therapy for tuberculosis 2023 ·Biomedicine & Pharmacotherapy ·Eusondia Arnett, Susanta Pahari, Chrissy M. Leopold Wager, (unknown), (unknown), (unknown), (unknown), María Montoya, Joseph T. Opferman, Larry S. Schlesinger	10
6	Requirement for antiapoptotic MCL-1 during early erythropoiesis 2021 ·Blood ·Meghan E. Turnis, (unknown), (unknown), (unknown), Peter Vogel, (unknown), Richard A. Ashmun, Paul A. Ney, Joseph T. Opferman	14
7	The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics 2020 ·Molecular Cancer Research ·(unknown), Amit Budhraja, J.A. Lynch, Kathryn G. Roberts, John C. Panetta, Jon P. Connelly, Meghan E. Turnis, Shondra M. Pruett‐Miller, John D. Schuetz, Charles G. Mullighan, Joseph T. Opferman	12
8	LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance 2018 ·Cell ·Larissa D. Cunha, Mao Yang, Robert Carter, Clifford S. Guy, (unknown), Jeremy Chase Crawford, Giovanni Quarato, Emilio Boada-Romero, Halime Kalkavan, Michael D. L. Johnson, Sivaraman Natarajan, Meghan E. Turnis, David Finkelstein, Joseph T. Opferman, Charles Gawad, Douglas R. Green	242
9	Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia 2017 ·Clinical Cancer Research ·Amit Budhraja, Meghan E. Turnis, Michelle L. Churchman, Anisha Kothari, Xue Yang, Haiyan Xu, (unknown), John C. Panetta, David Finkelstein, Charles G. Mullighan, Joseph T. Opferman	25
10	Male sterility in Mcl-1-flox mice is not due to enhanced Mcl1 protein stability 2016 ·Cell Death and Disease ·Casey Ah-Cann, Maximilien Tailler, Andrew J. Kueh, Marco J. Herold, Joseph T. Opferman, Marie-Liesse Asselin-Labat, Philippe Bouillet	3
11	Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling 2015 ·PLoS Genetics ·Suresh Marada, Gemma Navarro, (unknown), Daniel P. Stewart, Angela M. Arensdorf, Sigrid Nachtergaele, Edgar Angelats, Joseph T. Opferman, Rajat Rohatgi, Peter J. McCormick, Stacey K. Ogden	39
12	Ubiquitin-Independent Degradation of Antiapoptotic MCL-1 2010 ·Molecular and Cellular Biology ·Daniel P. Stewart, Brian Koss, Madhavi Bathina, (unknown), Kristen Bisanz, Joseph T. Opferman	106
13	Hepatocyte‐specific deletion of the antiapoptotic protein myeloid cell leukemia‐1 triggers proliferation and hepatocarcinogenesis in mice† 2009 ·Hepatology ·Achim Weber, Regina Boger, Binje Vick, Toni Urbanik, Johannes Haybaeck, Stefan Zoller, Andreas Teufel, Peter H. Krammer, Joseph T. Opferman, Peter R. Galle, Marcus Schuchmann, Mathias Heikenwälder, Henning Schulze‐Bergkamen	95
14	GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis 2009 ·Molecular Cell ·Renata Sano, Ida Annunziata, Annette Patterson, Simon Moshiach, Elida Gomero, Joseph T. Opferman, Michael Forte, Alessandra d’Azzo	236
15	Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes # 2008 ·Hepatology ·Binje Vick, Achim Weber, Toni Urbanik, T Maass, Andreas Teufel, Peter H. Krammer, Joseph T. Opferman, Marcus Schuchmann, Peter R. Galle, Henning Schulze‐Bergkamen	125
16	Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons 2008 ·Nature ·Jyh-Rong Chao, Evan Parganas, Kelli L. Boyd, Cheol Yi Hong, Joseph T. Opferman, James N. Ihle	200
17	Multiple signaling pathways promote B lymphocyte stimulator–dependent B-cell growth and survival 2007 ·Blood ·Robert T. Woodland, Casey Fox, Madelyn R. Schmidt, Peter S. Hammerman, Joseph T. Opferman, Stanley J. Korsmeyer, David M. Hilbert, Craig B. Thompson	152
18	Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance 2006 ·Cancer Cell ·Guo Wei, David Twomey, Justin Lamb, Krysta Schlis, Jyoti Agarwal, Ronald W. Stam, Joseph T. Opferman, Stephen E. Sallan, Monique L. den Boer, Rob Pieters, Todd R. Golub, Scott A. Armstrong	385
19	Obligate Role of Anti-Apoptotic MCL-1 in the Survival of Hematopoietic Stem Cells 2005 ·Science ·Joseph T. Opferman, Hiromi Iwasaki, Christy C. Ong, Heikyung Suh, Shin-ichi Mizuno, Koichi Akashi, Stanley J. Korsmeyer	446
20	Proapoptotic BAX and BAK control multiple initiator caspases 2005 ·EMBO Reports ·Antonio Ruiz‐Vela, Joseph T. Opferman, Emily H. Cheng, Stanley J. Korsmeyer	99

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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