Simon T. Hui

4.3k total citations · 2 hit papers
31 papers, 2.5k citations indexed

About

Simon T. Hui is a scholar working on Molecular Biology, Epidemiology and Physiology. According to data from OpenAlex, Simon T. Hui has authored 31 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 13 papers in Epidemiology and 9 papers in Physiology. Recurrent topics in Simon T. Hui's work include Liver Disease Diagnosis and Treatment (12 papers), Adipose Tissue and Metabolism (7 papers) and Redox biology and oxidative stress (7 papers). Simon T. Hui is often cited by papers focused on Liver Disease Diagnosis and Treatment (12 papers), Adipose Tissue and Metabolism (7 papers) and Redox biology and oxidative stress (7 papers). Simon T. Hui collaborates with scholars based in United States, Norway and Hong Kong. Simon T. Hui's co-authors include Aldons J. Lusis, Roger J. Davis, Nathaniel Heintz, Simin Lu, Mariko Hara, Bryan O’Sullivan-Murphy, Emiko Hayashi, Rita Bortell, Vinh Nguyen and Paul Greengard and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Hepatology.

In The Last Decade

Simon T. Hui

31 papers receiving 2.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

2012 696 citations Alana G. Lerner, Paurush Praveen et al. Cell Metabolism profile →
Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

2012 576 citations Christine M. Oslowski, Takashi Hara et al. Cell Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Simon T. Hui United States	18	1.3k	831	690	534	444	31	2.5k
Eric Vaillancourt Canada	10	1.2k 0.9×	1.3k 1.6×	1.1k 1.6×	714 1.3×	713 1.6×	12	3.1k
Mhairi C. Towler United Kingdom	17	2.0k 1.5×	646 0.8×	401 0.6×	588 1.1×	574 1.3×	19	2.8k
Eric D. Werner United States	12	1.5k 1.1×	629 0.8×	480 0.7×	234 0.4×	448 1.0×	15	2.3k
Ross Smith Sweden	7	805 0.6×	1.3k 1.5×	821 1.2×	643 1.2×	511 1.2×	11	2.3k
Ebru Erbay United States	19	1.4k 1.0×	492 0.6×	869 1.3×	407 0.8×	529 1.2×	27	2.8k
Dave Bridges United States	24	1.4k 1.1×	462 0.6×	361 0.5×	256 0.5×	385 0.9×	68	2.3k
Yup Kang South Korea	30	1.3k 1.0×	392 0.5×	962 1.4×	827 1.5×	537 1.2×	99	3.5k
Christine M. Oslowski United States	10	966 0.7×	1.1k 1.3×	480 0.7×	523 1.0×	172 0.4×	13	2.0k
Mireille Cormont France	33	2.3k 1.7×	963 1.2×	783 1.1×	732 1.4×	1.0k 2.3×	74	3.9k

Countries citing papers authored by Simon T. Hui

Since Specialization

Citations

This map shows the geographic impact of Simon T. Hui's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon T. Hui with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon T. Hui more than expected).

Fields of papers citing papers by Simon T. Hui

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon T. Hui. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon T. Hui. The network helps show where Simon T. Hui may publish in the future.

Co-authorship network of co-authors of Simon T. Hui

This figure shows the co-authorship network connecting the top 25 collaborators of Simon T. Hui. A scholar is included among the top collaborators of Simon T. Hui based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Simon T. Hui. Simon T. Hui is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Wang, Feng, Simon T. Hui, Frank Stappenbeck, et al.. (2025). Oxy210 Inhibits Hepatic Expression of Senescence-Associated, Pro-Fibrotic, and Pro-Inflammatory Genes in Mice During Development of MASH and in Hepatocytes In Vitro. Cells. 14(15). 1191–1191. 1 indexed citations

Stappenbeck, Frank, Satyesh K. Sinha, Simon T. Hui, et al.. (2024). Anti-Inflammatory Oxysterol, Oxy210, Inhibits Atherosclerosis in Hyperlipidemic Mice and Inflammatory Responses of Vascular Cells. Cells. 13(19). 1632–1632. 6 indexed citations

Hui, Simon T., Lili Gong, Montgomery Blencowe, et al.. (2023). Role of Matrix Gla Protein in Transforming Growth Factor-β Signaling and Nonalcoholic Steatohepatitis in Mice. Cellular and Molecular Gastroenterology and Hepatology. 16(6). 943–960. 6 indexed citations

Stappenbeck, Frank, Liu-Ya Tang, Ying E. Zhang, et al.. (2022). Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization. International Journal of Molecular Sciences. 23(10). 5478–5478. 14 indexed citations

Moore, Timothy M., Alexander R. Strumwasser, Amanda Lin, et al.. (2021). Effect of voluntary exercise upon the metabolic syndrome and gut microbiome composition in mice. Physiological Reports. 9(21). e15068–e15068. 8 indexed citations

Norheim, Frode, Yehudit Hasin-Brumshtein, Laurent Vergnes, et al.. (2019). Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. Cell Metabolism. 29(4). 932–949.e4. 79 indexed citations

Krishnan, Karthickeyan Chella, Zeyneb Kurt, Aditi Das, et al.. (2018). Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. Cell Systems. 6(1). 103–115.e7. 106 indexed citations

Lin, Liang‐Yu, Simon T. Hui, Marcus Seldin, et al.. (2018). Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans. G3 Genes Genomes Genetics. 8(11). 3499–3506. 11 indexed citations

Kurt, Zeyneb, Margarete Mehrabian, Calvin Pan, et al.. (2018). Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. Biology of Sex Differences. 9(1). 46–46. 61 indexed citations

10.

McLachlan, Stela, Kathryn Page, Seung-Min Lee, et al.. (2017). Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice. American Journal of Physiology-Gastrointestinal and Liver Physiology. 313(5). G511–G523. 7 indexed citations

11.

Norheim, Frode, Simon T. Hui, Margarete Mehrabian, et al.. (2016). Genetic and hormonal control of hepatic steatosis in female and male mice. Journal of Lipid Research. 58(1). 178–187. 47 indexed citations

12.

Lusis, Aldons J., Marcus Seldin, Hooman Allayee, et al.. (2016). The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. Journal of Lipid Research. 57(6). 925–942. 102 indexed citations

13.

Byon, Chang Hyun, Tie-Yan Han, Judy Wu, & Simon T. Hui. (2015). Txnip ablation reduces vascular smooth muscle cell inflammation and ameliorates atherosclerosis in apolipoprotein E knockout mice. Atherosclerosis. 241(2). 313–321. 55 indexed citations

14.

Mikhael, Marc, et al.. (2015). Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors. Experimental Hematology. 43(5). 393–403.e2. 5 indexed citations

15.

DeBalsi, Karen L., Kari E. Wong, Timothy R. Koves, et al.. (2014). Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle. Journal of Biological Chemistry. 289(12). 8106–8120. 48 indexed citations

16.

Oslowski, Christine M., Takashi Hara, Bryan O’Sullivan-Murphy, et al.. (2012). Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome. Cell Metabolism. 16(2). 265–273. 576 indexed citations breakdown →

17.

Lerner, Alana G., Paurush Praveen, Rajarshi Ghosh, et al.. (2012). IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress. Cell Metabolism. 16(2). 250–264. 696 indexed citations breakdown →

18.

Andres, Allen M., Eric P. Ratliff, Sowbarnika Sachithanantham, & Simon T. Hui. (2011). Diminished AMPK signaling response to fasting in thioredoxin-interacting protein knockout mice. FEBS Letters. 585(8). 1223–1230. 19 indexed citations

19.

Chen, Junqin, Simon T. Hui, Imran N. Mungrue, et al.. (2008). Thioredoxin‐interacting protein deficiency induces Akt/Bcl‐xL signaling and pancreatic beta‐cell mass and protects against diabetes. The FASEB Journal. 22(10). 3581–3594. 190 indexed citations

20.

Ng, T.B., Christopher H.K. Cheng, & Simon T. Hui. (1993). Peripheral administration of taurine antagonizes morphine-induced analgesia in mice. General Pharmacology The Vascular System. 24(2). 311–314. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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