Samir Softic

5.5k total citations · 2 hit papers
52 papers, 3.9k citations indexed

About

Samir Softic is a scholar working on Physiology, Epidemiology and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Samir Softic has authored 52 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Physiology, 26 papers in Epidemiology and 20 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Samir Softic's work include Liver Disease Diagnosis and Treatment (23 papers), Diet, Metabolism, and Disease (20 papers) and Diet and metabolism studies (16 papers). Samir Softic is often cited by papers focused on Liver Disease Diagnosis and Treatment (23 papers), Diet, Metabolism, and Disease (20 papers) and Diet and metabolism studies (16 papers). Samir Softic collaborates with scholars based in United States, Germany and Japan. Samir Softic's co-authors include David E. Cohen, C. Ronald Kahn, C. Ronald Kahn, Shiho Fujisaka, Rohit Kohli, Senad Divanovic, Lynn Bry, Siegfried Ussar, Jérémie Boucher and Christopher B. Newgard and has published in prestigious journals such as Journal of Clinical Investigation, Nature Communications and The EMBO Journal.

In The Last Decade

Samir Softic

52 papers receiving 3.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

2016 505 citations Samir Softic, David E. Cohen et al. profile →
Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

2015 420 citations Olivier Bézy, Shiho Fujisaka et al. Cell Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Samir Softic United States	28	1.8k	1.4k	1.4k	1.2k	419	52	3.9k
Isao Usui Japan	35	1.7k 0.9×	1.6k 1.1×	2.0k 1.5×	921 0.7×	653 1.6×	103	4.8k
Joel T. Haas United States	30	1.6k 0.9×	1.1k 0.8×	2.0k 1.4×	853 0.7×	1.0k 2.4×	48	4.8k
Motoyuki Kohjima Japan	29	1.5k 0.8×	744 0.5×	1.2k 0.8×	665 0.5×	589 1.4×	104	3.4k
Debby P.Y. Koonen Netherlands	31	1.2k 0.7×	1.2k 0.9×	2.0k 1.4×	617 0.5×	633 1.5×	53	3.9k
Terry D. Hinds United States	39	1.1k 0.6×	661 0.5×	2.3k 1.6×	771 0.6×	310 0.7×	94	3.9k
Ronit Shiri‐Sverdlov Netherlands	37	2.2k 1.2×	581 0.4×	1.5k 1.1×	861 0.7×	884 2.1×	108	4.4k
Rachel M. Fisher Sweden	41	1.6k 0.9×	1.5k 1.1×	1.4k 1.0×	1.5k 1.2×	804 1.9×	86	4.8k
Theo H. van Dijk Netherlands	32	1.4k 0.7×	1.7k 1.2×	2.5k 1.8×	801 0.6×	1.4k 3.3×	79	5.1k
Chengfu Xu China	38	2.5k 1.4×	480 0.3×	1.1k 0.8×	1.0k 0.8×	913 2.2×	183	4.9k
Takashi Goto Japan	22	967 0.5×	619 0.4×	1.4k 1.0×	533 0.4×	342 0.8×	92	3.0k

Countries citing papers authored by Samir Softic

Since Specialization

Citations

This map shows the geographic impact of Samir Softic's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Samir Softic with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Samir Softic more than expected).

Fields of papers citing papers by Samir Softic

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Samir Softic. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Samir Softic. The network helps show where Samir Softic may publish in the future.

Co-authorship network of co-authors of Samir Softic

This figure shows the co-authorship network connecting the top 25 collaborators of Samir Softic. A scholar is included among the top collaborators of Samir Softic based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Samir Softic. Samir Softic is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Park, Sehyung, Heba Ali, Yasir Alsiraj, et al.. (2024). Fructose-Induced Metabolic Dysfunction Is Dependent on the Baseline Diet, the Length of the Dietary Exposure, and Sex of the Mice. Nutrients. 17(1). 124–124. 1 indexed citations

Park, Sehyung, Lindsey R. Conroy, Harrison A. Clarke, et al.. (2024). Knockdown of ketohexokinase versus inhibition of its kinase activity exert divergent effects on fructose metabolism. JCI Insight. 9(23). 5 indexed citations

Gyawali, C. Prakash, Passisd Laoveeravat, Jordan D. Miller, et al.. (2023). Direct cost variance analysis of peroral endoscopic myotomy vs heller myotomy for management of achalasia: A tertiary referral center experience. World Journal of Gastrointestinal Endoscopy. 15(10). 593–601. 1 indexed citations

Sawada, Keisuke, Hak‐Jae Chung, Samir Softic, Maria E. Moreno‐Fernandez, & Senad Divanovic. (2023). The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease. Cell Metabolism. 35(11). 1852–1871. 58 indexed citations

Park, Sehyung, et al.. (2022). Fructose impairs fat oxidation: Implications for the mechanism of western diet-induced NAFLD. The Journal of Nutritional Biochemistry. 114. 109224–109224. 34 indexed citations

Moreau, F., Xiangyu Liu, Frédéric Tremblay, et al.. (2022). Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis. Journal of Lipid Research. 64(2). 100324–100324. 16 indexed citations

Damen, Michelle S. M. A., Traci E. Stankiewicz, Sehyung Park, et al.. (2021). Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae. International Journal of Obesity. 45(11). 2377–2387. 4 indexed citations

Homan, Erica P., Bruna B. Brandão, Samir Softic, et al.. (2021). Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue. Journal of Clinical Investigation. 131(19). 33 indexed citations

Cai, Weikang, Xuemei Zhang, Thiago M. Batista, et al.. (2021). Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens. Diabetes. 70(8). 1857–1873. 28 indexed citations

10.

Park, Sehyung, Robert N. Helsley, Leila Noetzli, et al.. (2021). A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes. STAR Protocols. 2(3). 100731–100731. 5 indexed citations

11.

Wang, Guoxiao, Yingying Yu, Weikang Cai, et al.. (2020). Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance. Diabetes. 69(11). 2294–2309. 9 indexed citations

12.

Helsley, Robert N., et al.. (2020). Tissue-Specific Fructose Metabolism in Obesity and Diabetes. Current Diabetes Reports. 20(11). 64–64. 48 indexed citations

13.

Helsley, Robert N. & Samir Softic. (2020). Fructose metabolism by the guts cuts liver fat. Journal of Molecular Medicine. 98(5). 733–734. 2 indexed citations

14.

Kwanten, Wilhelmus J., Jessica A. Carr, Ivy X. Chen, et al.. (2020). Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin. Nature Biomedical Engineering. 4(8). 801–813. 51 indexed citations

15.

Kwanten, Wilhelmus J., Jessica A. Carr, Ivy X. Chen, et al.. (2020). Author Correction: Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin. Nature Biomedical Engineering. 4(12). 1222–1222. 2 indexed citations

16.

Softic, Samir, Jesse G. Meyer, Manoj Gupta, et al.. (2019). Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. Cell Metabolism. 30(4). 735–753.e4. 160 indexed citations

17.

Rao, Tata Nageswara, Manoj Gupta, Samir Softic, et al.. (2018). Attenuation of PKC δ enhances metabolic activity and promotes expansion of blood progenitors. The EMBO Journal. 37(24). 5 indexed citations

18.

Meyer, Jesse G., Samir Softic, Nathan Basisty, et al.. (2018). Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose. PLoS ONE. 13(12). e0208973–e0208973. 38 indexed citations

19.

Softic, Samir, Manoj K. Gupta, Shiho Fujisaka, et al.. (2017). Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. Journal of Clinical Investigation. 127(11). 4059–4074. 261 indexed citations

20.

Softic, Samir, Michelle Kirby, Nicholas G. Berger, et al.. (2012). Insulin Concentration Modulates Hepatic Lipid Accumulation in Mice in Part via Transcriptional Regulation of Fatty Acid Transport Proteins. PLoS ONE. 7(6). e38952–e38952. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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