Isao Usui

6.5k citations

103 papers · 4.8k indexed · 2 hit papers · h-index 35

Impact in

Geriatrics and Gerontology top 1%
Physiology top 1%
- Adipose Tissue and Metabolism

Papers in

Geriatrics and Gerontology 8
- Sirtuins and Resveratrol in Medicine 8
Endocrinology, Diabetes and Metabolism 22
- Diabetes Treatment and Management 10

Co-authors: Masashi Kobayashi Kazuyuki Tobe Jerrold M. Olefsky Takeshi Imamura Shiho Fujisaka Hiroaki Satoh Tetsuro Haruta Masaharu Urakaze
Journals: Endocrinology (8 papers)Biochemical and Biophysical Research Communications (8 papers)Diabetes (7 papers)Journal of Biological Chemistry (6 papers)Scientific Reports (4 papers)
Partner nations: Japan United States Hungary

In The Last Decade

Isao Usui

99 papers receiving 4.7k citations

Hit Papers

align trajectories log scale

Evaluation of the effects of dapagliflozin, a sodium‐glucose co‐transporter‐2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non‐alcoholic fatty liver disease 2018 · 286 citations

Peers

Countries citing papers authored by Isao Usui

Since Specialization

Citations

This map shows the geographic impact of Isao Usui's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isao Usui with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isao Usui more than expected).

Fields of papers citing papers by Isao Usui

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isao Usui. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isao Usui. The network helps show where Isao Usui may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Isao Usui, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Isao Usui Line = papers co-authored together Isao Usui links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	High serum levels of CCL11/Eotaxin-1 are associated with diabetic sensorimotor polyneuropathy and peripheral nerve function but not with cardiac autonomic neuropathy in people with type 2 diabetes Postgraduate Medicine ·Yoshimasa Aso, Toshie Iijima, Teruo Jojima, Masahiro Saito, Louise Södervall, Matías Maximiliano Malleret, Shintaro Sakurai, Takuya Tomaru, Isao Usui	2024	3
2	Inhibition of IL-33 signaling ameliorate hepatic fibrosis with decreasing MCP-1 in a mouse model of diabetes and non-alcoholic steatohepatitis; comparison for luseogliflozin, an SGLT2 inhibitor Journal of Diabetes and its Complications ·Nick Smeets, Teruo Jojima, Masaaki Hashiguchi, M GIRI, Guadalupe Bravo, Shintaro Sakurai, Toshie Iijima, Takahiko Kogai, Takuya Tomaru, Isao Usui, Yoshimasa Aso	2023	9
3	Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet–Fed Mice International Journal of Molecular Sciences ·M GIRI, Isao Usui, Teruo Jojima, Shiho Fujisaka, Nick Smeets, Анастасия Михайловна Ежокина, Guadalupe Bravo, Shintaro Sakurai, Toshie Iijima, Takuya Tomaru, Kazuyuki Tobe, Yoshimasa Aso	2022	2
4	Transcription of cytochrome P450 46A1 in NIH3T3 cells is negatively regulated by FBS Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·潘潮, Hiromi Ando, Masamitsu Maekawa, 박형우, Yasuhiro Horibata, Motoyasu Satou, 氾桜田, Isao Usui, Yoshimasa Aso, Hiroyuki Sugimoto	2022	1
5	Acute effect of add‐on therapy with tofogliflozin, a sodium glucose co‐transporter 2 inhibitor, on 24‐hours glucose profile and glycaemic variability evaluated by continuous glucose monitoring in patients with type 2 diabetes receiving dipeptidyl peptidase‐4 inhibitors International Journal of Clinical Practice ·Toshie Iijima, 政茂石坂, James A. Benbrook, Danelly Castro, Shintaro Sakurai, Takuya Tomaru, Teruo Jojima, Isao Usui, Yoshimasa Aso	2021	2
6	Empagliflozin increases plasma levels of campesterol, a marker of cholesterol absorption, in patients with type 2 diabetes: Association with a slight increase in high-density lipoprotein cholesterol International Journal of Cardiology ·Teruo Jojima, Shintaro Sakurai, Nick Smeets, Toshie Iijima, Masahiro Saito, Takuya Tomaru, Takahiko Kogai, Isao Usui, Yoshimasa Aso	2021	19
7	A case of hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome with a novel frameshift variant in GATA3, p.W10Cfs40, lacks kidney malformation SHILAP Revista de lepidopterología ·M GIRI, Teruo Jojima, Takahiko Kogai, Toshie Iijima, Luc Nailis, Louise Södervall, 洋佑船戸, Kanako Kato, Mario Ocampo-Pineda, Kazumi Akimoto, Marija Mašonkina, Akira Hishinuma, Takuya Tomaru, Noriko Makita, Isao Usui, Yoshimasa Aso	2020	3
8	CD‐1^db/db mice: A novel type 2 diabetic mouse model with progressive kidney fibrosis Journal of Diabetes Investigation ·Abdel Halem Shawkat, Keizo Kanasaki, Kyoko Nitta, Yuka Nakamura, Yasuhito Ishigaki, Yuta Takagaki, Munehiro Kitada, Shaolan Li, Haijie Liu, Jinpeng Li, Isao Usui, Yoshimasa Aso, Daisuke Koya	2020	8
9	Bullous pemphigoid associated with dipeptidyl peptidase‐4 inhibitor showing unfavorable outcomes despite immediate discontinuation of medication SHILAP Revista de lepidopterología ·潘潮, Toshie Iijima, Shintaro Sakurai, Teruo Jojima, Luc Nailis, Shujiro Hayashi, Isao Usui, Ken Igawa, Yoshimasa Aso	2020	3
10	Ratio of low molecular weight serum adiponectin to the total adiponectin value is associated with type 2 diabetes through its relation to increasing insulin resistance PLoS ONE ·Minoru Iwata, Kazuo Hara, Stefania Onesti, 梦乡, Shiho Fujisaka, Manabu Ishiki, Isao Usui, Kunimasa Yagi, Yasuo Fukushima, Atsuko Takano, Hiromi Kato, Shihou Murakami, Kiyohiro Higuchi, Chikaaki Kobashi, Kazuhito Fukuda, Fernando C. Vasconcellos, Kazuyuki Tobe	2018	23
11	Adipose tissue-resident macrophages and obesity Allah Nawaz, Tomonobu Kado, Yoshiko Igarashi, 浩吉沢, Isao Usui, Shiho Fujisaka, Kazuyuki Tobe	2017	2
12	M2 macrophages in metabolism Diabetology International ·Shiho Fujisaka, Isao Usui, Allah Nawaz, Akiko Takikawa, Tomonobu Kado, Yoshiko Igarashi, Kazuyuki Tobe	2016	25
13	Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice Diabetologia ·Shiho Fujisaka, Isao Usui, Masashi Ikutani, Aminuddin Aminuddin, Akiko Takikawa, Koichi Tsuneyama, Amjad Mahmood, Nobuhito Goda, Yoshinori Nagai, Kiyoshi Takatsu, Kazuyuki Tobe	2013	186
14	Adenovirus-mediated chronic “hyper-resistinemia” leads to in vivo insulin resistance in normal rats Journal of Clinical Investigation ·Hiroaki Satoh, Matthew Nguyen, Philip D.G. Miles, Takeshi Imamura, Isao Usui, Jerrold M. Olefsky	2004	214
15	GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation The EMBO Journal ·Isao Usui, Takeshi Imamura, Hiroaki Satoh, Jie Huang, Jennie L. Babendure, Christopher J. Hupfeld, Jerrold M. Olefsky	2004	75
16	Potential Role of Gab1 and Phospholipase C-γ in Osmotic Shock-Induced Glucose Uptake in 3T3-L1 Adipocytes Hormone and Metabolic Research ·Eiichi Ueno, Tetsuro Haruta, Tatsuhito Uno, Isao Usui, Minoru Iwata, Atsuko Takano, Junko Kawahara, Toshiyasu Sasaoka, Osamu Ishibashi, Makoto Kobayashi	2001	7
17	Retinoblastoma Protein Phosphorylation via PI 3-Kinase and mTOR Pathway Regulates Adipocyte Differentiation Biochemical and Biophysical Research Communications ·Isao Usui, Tetsuro Haruta, Minoru Iwata, Atsuko Takano, Tatsuhito Uno, Junko Kawahara, Eiichi Ueno, Toshiyasu Sasaoka, Masashi Kobayashi	2000	23
18	Relative Involvement of Shc Tyrosine 239/240 and Tyrosine 317 on Insulin Induced Mitogenic Signaling in Rat1 Fibroblasts Expressing Insulin Receptors Biochemical and Biophysical Research Communications ·Hajime Ishihara, Toshiyasu Sasaoka, Tsutomu Wada, Manabu Ishiki, Tetsuro Haruta, Isao Usui, Minoru Iwata, Atsuko Takano, Tatsuhito Uno, Eiichi Ueno, Masashi Kobayashi	1998	19
19	Effect of glimepiride (HOE 490) on insulin receptors of skeletal muscles from genetically diabetic KK-Ay mouse European Journal of Pharmacology ·Yoshihisa Takada, Yasumitsu Takata, Masanori Iwanishi, Takeshi Imamura, Ann F. Schwartz, 卓司甲本, Hajime Ishihara, Manabu Ishiki, Isao Usui, R. Temaru, Masaharu Urakaze, Yusuke Satoh, Juancho Remulla, Shuji Tsuda, Atoosa Asadzadeh	1996	15
20	The dominant negative effect of a kinase-defective insulin receptor on insulin-like growth factor-I-stimulated signaling in Rat-1 fibroblasts Metabolism ·Yasumitsu Takata, Relita Resa, Tetsuro Haruta, Toshiyasu Sasaoka, 卓司甲本, Hajime Ishihara, Ann F. Schwartz, Isao Usui, Manabu Ishiki, Atoosa Asadzadeh	1996	6

About Isao Usui

Isao Usui is a scholar working on Geriatrics and Gerontology, Endocrinology, Diabetes and Metabolism, Physiology, Epidemiology and Endocrine and Autonomic Systems, having authored 103 papers that have together received 4.8k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (26 papers), Adipokines, Inflammation, and Metabolic Diseases (24 papers), Metabolism, Diabetes, and Cancer (24 papers), Pancreatic function and diabetes (14 papers), Protein Kinase Regulation and GTPase Signaling (13 papers), Diabetes Treatment and Management (10 papers), Liver Disease Diagnosis and Treatment (9 papers) and Sirtuins and Resveratrol in Medicine (8 papers). The work is most often cited by research in Geriatrics and Gerontology (301 citations), Physiology (1.6k citations), Endocrinology, Diabetes and Metabolism (921 citations), Epidemiology (1.7k citations) and Endocrine and Autonomic Systems (299 citations). Isao Usui has collaborated with scholars based in Japan, United States and Hungary. Frequent co-authors include Masashi Kobayashi, Kazuyuki Tobe, Jerrold M. Olefsky, Takeshi Imamura, Shiho Fujisaka, Hiroaki Satoh, Tetsuro Haruta, Masaharu Urakaze, Minoru Iwata and Toshiyasu Sasaoka. Their work appears in journals such as Endocrinology, Biochemical and Biophysical Research Communications, Diabetes, Journal of Biological Chemistry and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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