David W. Speicher

28.7k total citations · 7 hit papers
278 papers, 19.3k citations indexed

About

David W. Speicher is a scholar working on Molecular Biology, Physiology and Spectroscopy. According to data from OpenAlex, David W. Speicher has authored 278 papers receiving a total of 19.3k indexed citations (citations by other indexed papers that have themselves been cited), including 187 papers in Molecular Biology, 69 papers in Physiology and 60 papers in Spectroscopy. Recurrent topics in David W. Speicher's work include Erythrocyte Function and Pathophysiology (62 papers), Advanced Proteomics Techniques and Applications (56 papers) and Mass Spectrometry Techniques and Applications (39 papers). David W. Speicher is often cited by papers focused on Erythrocyte Function and Pathophysiology (62 papers), Advanced Proteomics Techniques and Applications (56 papers) and Mass Spectrometry Techniques and Applications (39 papers). David W. Speicher collaborates with scholars based in United States, Germany and Russia. David W. Speicher's co-authors include Hsin‐Yao Tang, Robert E. Handschumacher, Matthew W. Harding, Dennis E. Discher, Sandra L. Harper, Jeffrey S. Rice, Rhett J Drugge, Vincent T. Marchesi, V. Marchesi and Frank J. Rauscher and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

David W. Speicher

275 papers receiving 18.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

2013 1.5k citations Joe Swift, Irena L. Ivanovska et al. Science profile →
Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

1984 1.4k citations David W. Speicher et al. Science profile →
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

2008 667 citations Hsin‐Yao Tang, David W. Speicher et al. profile →
KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

1996 558 citations David W. Speicher et al. profile →
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

2015 492 citations Benjamin G. Bitler, Katherine M. Aird et al. profile →
Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

2013 487 citations David W. Speicher, Phyllis A. Gimotty et al. profile →
NAD+ metabolism governs the proinflammatory senescence-associated secretome

2019 282 citations Timothy Nacarelli, Takeshi Fukumoto et al. profile →

Peers

Countries citing papers authored by David W. Speicher

Since Specialization

Citations

This map shows the geographic impact of David W. Speicher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. Speicher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. Speicher more than expected).

Fields of papers citing papers by David W. Speicher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. Speicher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. Speicher. The network helps show where David W. Speicher may publish in the future.

Co-authorship network of co-authors of David W. Speicher

This figure shows the co-authorship network connecting the top 25 collaborators of David W. Speicher. A scholar is included among the top collaborators of David W. Speicher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David W. Speicher. David W. Speicher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation 2024 ·Nature Aging ·Hao Xue, Bo Zhao, (unknown), (unknown), (unknown), Xin Xu, (unknown), Hongzhuang Peng, Hsin‐Yao Tang, Aaron Havas, Andrew V. Kossenkov, Shelley L. Berger, Peter D. Adams, David W. Speicher, D. Schultz, Ronen Marmorstein, Kenneth S. Zaret, Rugang Zhang	17
2	Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy 2023 ·Clinical Proteomics ·Lynn A. Beer, Xiangfan Yin, (unknown), Suneeta Senapati, Mary D. Sammel, Kurt T. Barnhart, Qin Liu, David W. Speicher, Aaron R. Goldman	1
3	Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression 2023 ·Journal of Biological Chemistry ·(unknown), Irene Bertolini, Ekta Agarwal, Jagadish C. Ghosh, Hsin‐Yao Tang, David W. Speicher, Frederick Keeney, Khalid Sossey‐Alaoui, Elżbieta Pluskota, Katarzyna Białkowska, Edward F. Plow, Lucia R. Languino, Emmanuel Skordalakes, M. Cecilia Caino, Dario C. Altieri	3
4	Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition 2022 ·Cancer Discovery ·Vaibhav Jain, Sandra L. Harper, (unknown), Dylan Fingerman, (unknown), Monika Bhardwaj, Mary Ann S. Crissey, Aaron R. Goldman, Gordon Ruthel, Qin Liu, Aleksandra Živković, (unknown), Meenhard Herlyn, Phyllis A. Gimotty, David W. Speicher, Ravi K. Amaravadi	18
5	A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism 2021 ·PLoS Pathogens ·Jason Lamontagne, Samantha S. Soldan, Chenhe Su, Andreas Wiedmer, Kyoung‐Jae Won, Fang Lü, Aaron R. Goldman, Jayamanna Wickramasinghe, Hsin‐Yao Tang, David W. Speicher, Louise C. Showe, Andrew V. Kossenkov, Paul M. Lieberman	28
6	The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells 2020 ·Science Signaling ·Jie Li, Ekta Agarwal, Irene Bertolini, Jae Ho Seo, M. Cecilia Caino, Jagadish C. Ghosh, Andrew V. Kossenkov, Qin Liu, Hsin‐Yao Tang, Aaron R. Goldman, Lucia R. Languino, David W. Speicher, Dario C. Altieri	57
7	Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence 2020 ·Nature Communications ·Bo Zhao, Pingyu Liu, Takeshi Fukumoto, Timothy Nacarelli, Nail Fatkhutdinov, Shuai Wu, Jianhuang Lin, Katherine M. Aird, Hsin‐Yao Tang, Qin Liu, David W. Speicher, Rugang Zhang	51
8	Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth 2019 ·Journal of Biological Chemistry ·Ekta Agarwal, Brian J. Altman, Jae Ho Seo, Jagadish C. Ghosh, Andrew V. Kossenkov, Hsin‐Yao Tang, Shiv Ram Krishn, Lucia R. Languino, Dmitry I. Gabrilovich, David W. Speicher, Chi V. Dang, Dario C. Altieri	24
9	ARID1A spatially partitions interphase chromosomes 2019 ·Science Advances ·Shuai Wu, Nail Fatkhutdinov, Leah F. Rosin, Jennifer M. Luppino, Osamu Iwasaki, Hideki Tanizawa, Hsin‐Yao Tang, Andrew V. Kossenkov, Alessandro Gardini, Ken-ichi Noma, David W. Speicher, Eric F. Joyce, Rugang Zhang	25
10	Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements 2018 ·Cancer Research ·Jae Ho Seo, Ekta Agarwal, Kelly G. Bryant, M. Cecilia Caino, Eui Tae Kim, Andrew V. Kossenkov, Hsin‐Yao Tang, Lucia R. Languino, Dmitry I. Gabrilovich, Andrew R. Cohen, David W. Speicher, Dario C. Altieri	42
11	CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer 2018 ·Scientific Reports ·(unknown), Sandra L. Harper, Aaron R. Goldman, Benjamin G. Bitler, Katherine M. Aird, Mark E. Borowsky, Mark G. Cadungog, Qin Liu, Rugang Zhang, Stéphanie Jean, Ronny Drapkin, David W. Speicher	33
12	BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer 2016 ·Cancer Research ·Yuhki Yokoyama, Hengrui Zhu, Jeong Heon Lee, Andrew V. Kossenkov, Sherry Y. Wu, Jayamanna Wickramasinghe, Xiangfan Yin, Katherine C. Palozola, Alessandro Gardini, Louise C. Showe, Kenneth S. Zaret, Qin Liu, David W. Speicher, José R. Conejo-García, James E. Bradner, Zhiguo Zhang, Anil K. Sood, Tamás Ördög, Benjamin G. Bitler, Rugang Zhang	116
13	The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis 2016 ·PLoS Biology ·Jae Ho Seo, Dayana B. Rivadeneira, M. Cecilia Caino, Young Chan Chae, David W. Speicher, Hsin‐Yao Tang, Valentina Vaira, Silvano Bòsari, A. Palleschi, Paolo Rampini, Andrew V. Kossenkov, Lucia R. Languino, Dario C. Altieri	142
14	Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry 2014 ·Proceedings of the National Academy of Sciences ·Sira Sriswasdi, Sandra L. Harper, Hsin‐Yao Tang, Patrick G. Gallagher, David W. Speicher	15
15	Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation breakdown → 2013 ·Science ·Joe Swift, Irena L. Ivanovska, Amnon Buxboim, Takamasa Harada, P.C. Dave P. Dingal, (unknown), J. David Pajerowski, Kyle Spinler, Jae‐Won Shin, Manorama Tewari, Florian Rehfeldt, David W. Speicher, Dennis E. Discher	1498
16	SP11 Reducing Sample Complexity for Proteomics 2007 ·Journal of Biomolecular Techniques JBT ·David W. Speicher	1
17	Forced unfolding modulated by disulfide bonds in the immunoglobulin domains of a cell adhesion molecule 2001 ·APS March Meeting Abstracts ·Dennis E. Discher, Philippe Carl, Gavin A. Manderson, David W. Speicher	1
18	High-Sensitivity Gas Phase Sequence Analysis of Proteins and Peptides on PVDF Membranes Using Short Cycle Times 1993 ·Analytical Biochemistry ·(unknown), David W. Speicher	5
19	High yield electroblotting onto polyvinylidene difluoride membranes from polyacrylamide gels 1992 ·Electrophoresis ·Jacek Mozdzanowski, Peter Hembach, David W. Speicher	44
20	Mutant forms of spectrin alpha-subunits in hereditary elliptocytosis. 1987 ·Journal of Clinical Investigation ·Sally L. Marchesi, (unknown), David W. Speicher, V. Marchesi, Peter Agre, (unknown), Gunsagar S. Gulati	58

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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