Paul A. Brough

2.4k total citations
19 papers, 803 citations indexed

About

Paul A. Brough is a scholar working on Molecular Biology, Computational Theory and Mathematics and Organic Chemistry. According to data from OpenAlex, Paul A. Brough has authored 19 papers receiving a total of 803 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 8 papers in Computational Theory and Mathematics and 3 papers in Organic Chemistry. Recurrent topics in Paul A. Brough's work include Heat shock proteins research (9 papers), Computational Drug Discovery Methods (8 papers) and ATP Synthase and ATPases Research (4 papers). Paul A. Brough is often cited by papers focused on Heat shock proteins research (9 papers), Computational Drug Discovery Methods (8 papers) and ATP Synthase and ATPases Research (4 papers). Paul A. Brough collaborates with scholars based in United Kingdom, Canada and Switzerland. Paul A. Brough's co-authors include Martin J. Drysdale, Paul Workman, Edward McDonald, Andrew J. Massey, Lisa Wright, Stephen D. Roughley, Xavier Barril, A.E. Surgenor, Roderick E. Hubbard and Keith Jones and has published in prestigious journals such as Journal of Medicinal Chemistry, Tetrahedron Letters and The Analyst.

In The Last Decade

Paul A. Brough

19 papers receiving 777 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Paul A. Brough United Kingdom 13 553 213 200 90 60 19 803
Brian S. Lucas United States 13 667 1.2× 177 0.8× 282 1.4× 99 1.1× 126 2.1× 16 891
Isabelle Morize France 10 534 1.0× 200 0.9× 226 1.1× 14 0.2× 33 0.6× 19 760
Werngard Czechtizky Germany 18 394 0.7× 134 0.6× 362 1.8× 16 0.2× 36 0.6× 49 871
Robert Downham United Kingdom 11 289 0.5× 137 0.6× 322 1.6× 19 0.2× 15 0.3× 12 582
Srinivas Rao Kasibhatla United States 15 689 1.2× 123 0.6× 393 2.0× 54 0.6× 81 1.4× 25 1.1k
Pathik S. Brahmkshatriya India 13 326 0.6× 132 0.6× 449 2.2× 26 0.3× 17 0.3× 28 844
Laura Maccari Italy 16 337 0.6× 117 0.5× 225 1.1× 11 0.1× 26 0.4× 24 662
Helen Browne United Kingdom 6 351 0.6× 49 0.2× 349 1.7× 34 0.4× 44 0.7× 8 742
Thomas E. Barta United States 15 319 0.6× 49 0.2× 253 1.3× 27 0.3× 48 0.8× 25 649
Stéphane De Cesco Canada 11 316 0.6× 150 0.7× 200 1.0× 27 0.3× 17 0.3× 12 487

Countries citing papers authored by Paul A. Brough

Since Specialization
Citations

This map shows the geographic impact of Paul A. Brough's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul A. Brough with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul A. Brough more than expected).

Fields of papers citing papers by Paul A. Brough

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul A. Brough. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul A. Brough. The network helps show where Paul A. Brough may publish in the future.

Co-authorship network of co-authors of Paul A. Brough

This figure shows the co-authorship network connecting the top 25 collaborators of Paul A. Brough. A scholar is included among the top collaborators of Paul A. Brough based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul A. Brough. Paul A. Brough is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

19 of 19 papers shown
1.
Luchinat, Enrico, et al.. (2024). Ligand-Based Competition Binding by Real-Time 19F NMR in Human Cells. Journal of Medicinal Chemistry. 67(2). 1115–1126. 10 indexed citations
2.
Moore, Jonathan D., Anna D. Staniszewska, Ben Davis, et al.. (2014). VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Oncotarget. 5(24). 12862–12876. 51 indexed citations
3.
Murray, James B., Stephen D. Roughley, Natalia Matassova, & Paul A. Brough. (2014). Off-Rate Screening (ORS) By Surface Plasmon Resonance. An Efficient Method to Kinetically Sample Hit to Lead Chemical Space from Unpurified Reaction Products. Journal of Medicinal Chemistry. 57(7). 2845–2850. 46 indexed citations
4.
Roughley, Stephen D., Lisa Wright, Paul A. Brough, Andrew J. Massey, & Roderick E. Hubbard. (2011). Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening. Topics in current chemistry. 317. 61–82. 21 indexed citations
5.
Massey, Andrew J., Joseph Schoepfer, Paul A. Brough, et al.. (2010). Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800. Molecular Cancer Therapeutics. 9(4). 906–919. 50 indexed citations
6.
Drysdale, Martin J. & Paul A. Brough. (2008). Medicinal Chemistry of Hsp90 Inhibitors. Current Topics in Medicinal Chemistry. 8(10). 859–868. 29 indexed citations
7.
Brough, Paul A., Andrew J. Massey, Martin J. Drysdale, et al.. (2007). NVP-AUY922 / VER-52296: A novel 3,4 diarylisoxazole Hsp90 chaperone inhibitor discovered via structure-based drug design. Molecular Cancer Therapeutics. 6. 1 indexed citations
8.
McDonald, Edward, Keith Jones, Paul A. Brough, Martin J. Drysdale, & Paul Workman. (2006). Discovery and Development of Pyrazole-Scaffold Hsp90 Inhibitors. Current Topics in Medicinal Chemistry. 6(11). 1193–1203. 122 indexed citations
9.
Drysdale, Martin J., Paul A. Brough, Andrew E. Massey, Michael Rugaard Jensen, & Joseph Schoepfer. (2006). Targeting Hsp90 for the treatment of cancer.. PubMed. 9(4). 483–95. 85 indexed citations
10.
Brough, Paul A., Xavier Barril, Mandy Beswick, et al.. (2005). 3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone. Bioorganic & Medicinal Chemistry Letters. 15(23). 5197–5201. 66 indexed citations
11.
Barril, Xavier, Paul A. Brough, Martin J. Drysdale, et al.. (2005). Structure-based discovery of a new class of Hsp90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 15(23). 5187–5191. 58 indexed citations
12.
Dymock, Brian, Xavier Barril, Paul A. Brough, et al.. (2005). Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design. Journal of Medicinal Chemistry. 48(13). 4212–4215. 177 indexed citations
13.
Brough, Paul A., et al.. (1998). Synthesis of 2-iodo- and 2-phenyl-[11C]melatonin: potential PET tracers for melatonin binding sites. Applied Radiation and Isotopes. 49(12). 1573–1579. 6 indexed citations
14.
15.
Wonnacott, Susan, et al.. (1995). Anatoxin-a is a potent agonist of the nicotinic acetylcholine receptor of bovine adrenal chromaffin cells. European Journal of Pharmacology Molecular Pharmacology. 289(3). 447–453. 28 indexed citations
16.
Haugen, John‐Erik, Olav M. Skulberg, Roger A. Andersen, et al.. (1995). Rapid analysis of cyanophyte neurotoxins: An improved method for quantitative analysis of anatoxin-α and homoanatoxin-α in the sub-ppb to ppb range. Algological Studies/Archiv für Hydrobiologie Supplement Volumes. 75. 111–121. 7 indexed citations
17.
Brough, Paul A., et al.. (1994). Alkyl‐modified side chain variants of anatoxin‐a: A series of potent nicotinic agonists. Drug Development Research. 31(2). 147–156. 10 indexed citations
18.
Zotou, Anastasia, T.M. Jefferies, Paul A. Brough, & Timothy Gallagher. (1993). Determination of anatoxin-a and homoanatoxin in blue—green algal extracts by high-performance liquid chromatography and gas chromatography—mass spectrometry. The Analyst. 118(7). 753–758. 16 indexed citations
19.
Brough, Paul A., et al.. (1992). Synthesis and X-ray crystal structure of 2-acetyl-9-azabicyclo[4.2.1]nonan-3-one. A conformationally locked s-cis analogue of anatoxin-a. Journal of the Chemical Society Chemical Communications. 1087–1087. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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