A.E. Surgenor

4.3k citations

21 papers · 1.7k indexed · h-index 18

Molecular Biology top 10%
Organic Chemistry top 5%
Computational Theory and Mathematics top 1%
Oncology
Pharmacology top 5%

Co-authors: Rob Howes Alan Robertson Nicolas Foloppe Andrew Potter Martin J. Drysdale Xavier Barril Andrew J. Massey Lisa Wright
Topics: Computational Drug Discovery Methods (9 papers)Heat shock proteins research (9 papers)Enzyme Structure and Function (5 papers)
Cited by: Computational Theory and Mathematics Organic Chemistry Physical and Theoretical Chemistry
Journals: Analytical Biochemistry Biochemical and Biophysical Research Communications Journal of Medicinal Chemistry
Partner nations: United Kingdom France Denmark

In The Last Decade

A.E. Surgenor

21 papers receiving 1.7k citations

Peers

Countries citing papers authored by A.E. Surgenor

Since Specialization

Citations

This map shows the geographic impact of A.E. Surgenor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A.E. Surgenor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A.E. Surgenor more than expected).

Fields of papers citing papers by A.E. Surgenor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A.E. Surgenor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A.E. Surgenor. The network helps show where A.E. Surgenor may publish in the future.

Co-authorship network of co-authors of A.E. Surgenor

This figure shows the co-authorship network connecting the top 25 collaborators of A.E. Surgenor. A scholar is included among the top collaborators of A.E. Surgenor based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A.E. Surgenor. A.E. Surgenor is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design and Synthesis of Pyrrolo[2,3-d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate 2021 ·Journal of Medicinal Chemistry ·D.S. Williamson,Garrick P. Smith,(unknown),(unknown),(unknown),Lassina Badolo,(unknown),(unknown),I‐Jen Chen,P. Dokurno,Morten Hentzer,(unknown),Stuart Ray,T. Shaw,A.E. Surgenor,(unknown),Yikang Wang,Kenneth Vielsted Christensen	23
2	Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B 2021 ·Journal of Medicinal Chemistry ·Lee Walmsley,James B. Murray,P. Dokurno,Andrew J. Massey,Karen Benwell,(unknown),Nicolas Foloppe,Stuart Ray,(unknown),A.E. Surgenor,(unknown),(unknown),Mike F. Burbridge,Francisco Cruzalegui,András Kotschy,Roderick E. Hubbard	31
3	Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures 2020 ·Communications Chemistry ·Lisa Baker,A. Aimon,James B. Murray,A.E. Surgenor,Natalia Matassova,Stephen D. Roughley,P.M. Collins,T. Krojer,F. von Delft,Roderick E. Hubbard	12
4	Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity 2011 ·Journal of Medicinal Chemistry ·Alba T. Macias,D.S. Williamson,Nicola J. Allen,Jenifer Borgognoni,(unknown),Zoe Daniels,P. Dokurno,Martin J. Drysdale,Geraint L. Francis,Christopher J Graham,Rob Howes,Natalia Matassova,James B. Murray,Rachel Parsons,T. Shaw,A.E. Surgenor,(unknown),Yikang Wang,Mike Wood,Andrew J. Massey	88
5	Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution 2010 ·Bioorganic & Medicinal Chemistry Letters ·Andrew Potter,(unknown),(unknown),Christophe Fromont,Stuart Ray,Christopher J. Northfield,Chris Bryant,Simon Scrace,David A. Robinson,(unknown),Lisa Baker,P. Dokurno,A.E. Surgenor,Ben Davis,Christine M. Richardson,James B. Murray,Jonathan D. Moore	69
6	Structure-guided design of α-amino acid-derived Pin1 inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·Andrew Potter,Stuart Ray,(unknown),(unknown),Chris Bryant,Simon Scrace,Natalia Matassova,Lisa Baker,P. Dokurno,David A. Robinson,A.E. Surgenor,Ben Davis,James B. Murray,Christine M. Richardson,Jonathan D. Moore	73
7	Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design 2009 ·Journal of Medicinal Chemistry ·D.S. Williamson,Jenifer Borgognoni,(unknown),Zoe Daniels,P. Dokurno,Martin J. Drysdale,Nicolas Foloppe,Geraint L. Francis,Christopher J Graham,Rob Howes,Alba T. Macias,James B. Murray,Rachel Parsons,T. Shaw,A.E. Surgenor,(unknown),Yikang Wang,Mike Wood,Andrew J. Massey	175
8	Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping 2007 ·Bioorganic & Medicinal Chemistry Letters ·Christine M. Richardson,(unknown),D.S. Williamson,Martin J. Parratt,P. Dokurno,Rob Howes,Jenifer Borgognoni,Martin J. Drysdale,Harry Finch,Roderick E. Hubbard,Philip S. Jackson,(unknown),Georg Lentzen,Jonathan D. Moore,James B. Murray,Heather Simmonite,A.E. Surgenor,C Torrance	38
9	4-Amino derivatives of the Hsp90 inhibitor CCT018159 2006 ·Bioorganic & Medicinal Chemistry Letters ·Xavier Barril,Mandy Beswick,Adam J. Collier,Martin J. Drysdale,Brian Dymock,Alexandra Fink,(unknown),Robert I. Howes,Allan M. Jordan,Andrew J. Massey,A.E. Surgenor,(unknown),Paul Workman,Lisa Wright	67
10	A fluorescence polarization assay for inhibitors of Hsp90 2006 ·Analytical Biochemistry ·R. Howes,Xavier Barril,Brian Dymock,(unknown),Christopher J. Northfield,Alan Robertson,A.E. Surgenor,(unknown),(unknown),Karen James,Thomas P. Matthews,(unknown),Edward McDonald,Paul Workman,Martin J. Drysdale	61
11	Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening 2006 ·Bioorganic & Medicinal Chemistry ·Nicolas Foloppe,(unknown),Rob Howes,Andrew Potter,Alan Robertson,A.E. Surgenor	317
12	Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SAR 2005 ·Bioorganic & Medicinal Chemistry Letters ·Christine M. Richardson,D.S. Williamson,Martin J. Parratt,Jenifer Borgognoni,Andrew D. Cansfield,P. Dokurno,Geraint L. Francis,Rob Howes,Jonathan D. Moore,James B. Murray,Alan Robertson,A.E. Surgenor,C Torrance	56
13	3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone 2005 ·Bioorganic & Medicinal Chemistry Letters ·Paul A. Brough,Xavier Barril,Mandy Beswick,Brian Dymock,Martin J. Drysdale,Lisa Wright,(unknown),Andrew J. Massey,A.E. Surgenor,Paul Workman	66
14	Structure-based discovery of a new class of Hsp90 inhibitors 2005 ·Bioorganic & Medicinal Chemistry Letters ·Xavier Barril,Paul A. Brough,Martin J. Drysdale,Roderick E. Hubbard,Andrew J. Massey,A.E. Surgenor,Lisa Wright	58
15	Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2 2005 ·Bioorganic & Medicinal Chemistry Letters ·D.S. Williamson,Martin J. Parratt,Justin Bower,Jonathan D. Moore,Christine M. Richardson,P. Dokurno,Andrew D. Cansfield,Geraint L. Francis,(unknown),Rob Howes,Philip S. Jackson,(unknown),James B. Murray,(unknown),(unknown),Alan Robertson,A.E. Surgenor,C Torrance	60
16	Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design 2005 ·Journal of Medicinal Chemistry ·Brian Dymock,Xavier Barril,Paul A. Brough,Julie E. Cansfield,Andrew J. Massey,Edward McDonald,Roderick E. Hubbard,A.E. Surgenor,Stephen D. Roughley,Paul Webb,Paul Workman,Lisa Wright,Martin J. Drysdale	177
17	Structure-Based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein−Ligand Affinity 2005 ·Journal of Medicinal Chemistry ·Nicolas Foloppe,(unknown),Rob Howes,(unknown),Andrew Potter,Alan Robertson,A.E. Surgenor	82
18	Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms 2004 ·Chemistry & Biology ·Lisa Wright,Xavier Barril,Brian Dymock,(unknown),A.E. Surgenor,Mandy Beswick,Martin J. Drysdale,Adam J. Collier,Andy Massey,Nicholas G. Davies,(unknown),Christophe Fromont,Wynne Aherne,Kathy Boxall,Swee Y. Sharp,Paul Workman,Roderick E. Hubbard	210
19	Adenine derived inhibitors of the molecular chaperone HSP90—SAR explained through multiple X-ray structures 2003 ·Bioorganic & Medicinal Chemistry Letters ·Brian Dymock,Xavier Barril,Mandy Beswick,Adam J. Collier,Nicholas G. Davies,Martin J. Drysdale,Alexandra Fink,Christophe Fromont,Roderick E. Hubbard,Andrew J. Massey,A.E. Surgenor,Lisa Wright	52
20	Comparison of peptide aldehydes with α1-antitrypsin as elastase inhibitors for use in emphysema 1986 ·Biochemical and Biophysical Research Communications ·N. A. Roberts,A.E. Surgenor	5

About A.E. Surgenor

A.E. Surgenor is a scholar working on Computational Theory and Mathematics, Physical and Theoretical Chemistry and Molecular Biology, having authored 21 papers that have together received 1.7k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (9 papers), Heat shock proteins research (9 papers) and Enzyme Structure and Function (5 papers). The work is most often cited by research in Computational Theory and Mathematics (463 citations), Organic Chemistry (563 citations) and Physical and Theoretical Chemistry (147 citations). A.E. Surgenor has collaborated with scholars based in United Kingdom, France and Denmark. Frequent co-authors include Rob Howes, Alan Robertson, Nicolas Foloppe, Andrew Potter, Martin J. Drysdale, Xavier Barril, Andrew J. Massey, Lisa Wright, Brian Dymock and Roderick E. Hubbard. Their work appears in journals such as Analytical Biochemistry, Biochemical and Biophysical Research Communications and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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