Robert P. Mecham

24.8k total citations · 4 hit papers
317 papers, 18.9k citations indexed

About

Robert P. Mecham is a scholar working on Genetics, Molecular Biology and Cancer Research. According to data from OpenAlex, Robert P. Mecham has authored 317 papers receiving a total of 18.9k indexed citations (citations by other indexed papers that have themselves been cited), including 191 papers in Genetics, 99 papers in Molecular Biology and 82 papers in Cancer Research. Recurrent topics in Robert P. Mecham's work include Connective tissue disorders research (188 papers), Protease and Inhibitor Mechanisms (77 papers) and Cell Adhesion Molecules Research (49 papers). Robert P. Mecham is often cited by papers focused on Connective tissue disorders research (188 papers), Protease and Inhibitor Mechanisms (77 papers) and Cell Adhesion Molecules Research (49 papers). Robert P. Mecham collaborates with scholars based in United States, Canada and Italy. Robert P. Mecham's co-authors include Jessica E. Wagenseil, Thomas J. Broekelmann, Robert M. Senior, Gail L. Griffin, William C. Parks, Joel Rosenbloom, Elaine C. Davis, Kurt R. Stenmark, Russell H. Knutsen and David S. Wrenn and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Robert P. Mecham

316 papers receiving 18.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Vascular Extracellular Matrix and Arterial Mechanics

2009 716 citations Jessica E. Wagenseil, Robert P. Mecham profile →
Elastin is an essential determinant of arterial morphogenesis

1998 579 citations Robert P. Mecham, Mark T. Keating et al. profile →
Extracellular matrix 4: The elastic fiber

1993 479 citations Robert P. Mecham et al. profile →
Chemotactic activity of elastin-derived peptides.

1980 413 citations Robert P. Mecham et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert P. Mecham United States	71	7.7k	5.8k	4.9k	3.9k	2.6k	317	18.9k
Daniel B. Rifkin United States	92	5.4k 0.7×	17.5k 3.0×	4.4k 0.9×	6.7k 1.7×	3.2k 1.2×	230	32.7k
William C. Parks United States	74	2.1k 0.3×	6.3k 1.1×	4.4k 0.9×	6.4k 1.6×	3.1k 1.2×	231	22.3k
Steffen Gay Switzerland	103	2.6k 0.3×	13.8k 2.4×	2.6k 0.5×	6.0k 1.6×	3.6k 1.4×	523	36.4k
Sergio A. Jiménez United States	78	2.3k 0.3×	6.0k 1.0×	3.0k 0.6×	1.8k 0.5×	2.8k 1.1×	390	20.9k
Thomas N. Wight United States	88	2.5k 0.3×	10.5k 1.8×	2.4k 0.5×	4.7k 1.2×	4.5k 1.7×	328	25.1k
Harry C. Dietz United States	83	15.2k 2.0×	8.0k 1.4×	12.1k 2.5×	2.8k 0.7×	4.3k 1.6×	251	28.2k
Paul Börnstein United States	93	3.6k 0.5×	13.8k 2.4×	1.5k 0.3×	5.4k 1.4×	2.3k 0.9×	277	27.2k
Robert M. Senior United States	76	1.8k 0.2×	5.3k 0.9×	6.1k 1.3×	6.1k 1.6×	2.5k 0.9×	192	21.0k
Steven Μ. Albelda United States	96	4.1k 0.5×	10.6k 1.8×	5.2k 1.1×	2.8k 0.7×	2.0k 0.8×	315	35.5k
Andrew H. Baker United Kingdom	73	4.3k 0.6×	10.3k 1.8×	1.8k 0.4×	6.2k 1.6×	2.0k 0.8×	316	18.1k

Countries citing papers authored by Robert P. Mecham

Since Specialization

Citations

This map shows the geographic impact of Robert P. Mecham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert P. Mecham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert P. Mecham more than expected).

Fields of papers citing papers by Robert P. Mecham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert P. Mecham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert P. Mecham. The network helps show where Robert P. Mecham may publish in the future.

Co-authorship network of co-authors of Robert P. Mecham

This figure shows the co-authorship network connecting the top 25 collaborators of Robert P. Mecham. A scholar is included among the top collaborators of Robert P. Mecham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert P. Mecham. Robert P. Mecham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Chen, Yen‐Lin, Bruce A. Corliss, Chien‐Jung Lin, et al.. (2023). Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1. JCI Insight. 8(9). 4 indexed citations

2.

Cocciolone, Austin J., et al.. (2023). Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts. Journal of Biomechanical Engineering. 146(6). 4 indexed citations

3.

Kobbe, Birgit, Bert Callewaert, Gerhard Sengle, et al.. (2022). LTBP1 promotes fibrillin incorporation into the extracellular matrix. Matrix Biology. 110. 60–75. 15 indexed citations

4.

Kim, Jungsil, Austin J. Cocciolone, Marius C. Staiculescu, Robert P. Mecham, & Jessica E. Wagenseil. (2021). Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin. Journal of the mechanical behavior of biomedical materials. 126. 105021–105021. 6 indexed citations

5.

Jung, In‐Hyuk, Arturo Alisio, Erica P. Young, et al.. (2021). SVEP1 is a human coronary artery disease locus that promotes atherosclerosis. Science Translational Medicine. 13(586). 34 indexed citations

6.

Kim, Jungsil, Austin J. Cocciolone, Marius C. Staiculescu, Robert P. Mecham, & Jessica E. Wagenseil. (2019). Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice. Biomechanics and Modeling in Mechanobiology. 19(1). 99–112. 8 indexed citations

7.

Lee, Vivian S., Carmen M. Halabi, Thomas J. Broekelmann, et al.. (2019). Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress. JCI Insight. 4(15). 14 indexed citations

8.

Mecham, Robert P. & Francesco Ramirez. (2018). Extracellular Determinants of Arterial Morphogenesis, Growth, and Homeostasis. Current topics in developmental biology. 130. 193–216. 6 indexed citations

9.

Kabir, Ashraf Ul, Tae‐Jin Lee, Hua Pan, et al.. (2018). Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis. JCI Insight. 3(8). 18 indexed citations

10.

Stoilov, Ivan, Barry Starcher, Robert P. Mecham, & Thomas J. Broekelmann. (2017). Measurement of elastin, collagen, and total protein levels in tissues. Methods in cell biology. 143. 133–146. 65 indexed citations

11.

Jarad, George, Russell H. Knutsen, Robert P. Mecham, & Jeffrey H. Miner. (2016). Albumin contributes to kidney disease progression in Alport syndrome. American Journal of Physiology-Renal Physiology. 311(1). F120–F130. 37 indexed citations

12.

Zhang, Pei, Angela Huang, Jacopo Ferruzzi, et al.. (2011). Inhibition of MicroRNA-29 Enhances Elastin Levels in Cells Haploinsufficient for Elastin and in Bioengineered Vessels—Brief Report. Arteriosclerosis Thrombosis and Vascular Biology. 32(3). 756–759. 84 indexed citations

13.

Wagenseil, Jessica E., et al.. (2009). Reduced Vessel Elasticity Alters Cardiovascular Structure and Function in Newborn Mice. Circulation Research. 104(10). 1217–1224. 85 indexed citations

14.

Cheng, Alan, Loretha Myers, Francisco Martínez-Murillo, et al.. (2004). TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. Journal of Clinical Investigation. 114(11). 1586–1592. 360 indexed citations

15.

Cheng, Alan, Loretha Myers, Francisco Martínez-Murillo, et al.. (2004). TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. Journal of Clinical Investigation. 114(11). 1586–1592. 403 indexed citations

16.

Faury, Gilles, Dan Taylor, Elise Davis, et al.. (1998). Novel arterial pathology in mice and humans hemizygous for elastin.. Journal of Clinical Investigation. 102(10). 1783–1787. 262 indexed citations

17.

Hinek, Aleksander, Robert P. Mecham, Fred W. Keeley, & Marlene Rabinovitch. (1991). Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfate.. Journal of Clinical Investigation. 88(6). 2083–2094. 110 indexed citations

18.

Mecham, Robert P.. (1987). [12] Modulation of elastin synthesis: In vitro models. Methods in enzymology on CD-ROM/Methods in enzymology. 144. 232–246. 30 indexed citations

19.

Mecham, Robert P., et al.. (1986). Structural characteristics and intermolecular organization of human pulmonary-surfactant-associated proteins. Biochemical Journal. 240(1). 107–114. 17 indexed citations

20.

Parks, William C., David S. Wrenn, & Robert P. Mecham. (1986). Multiple forms of tropoelastin produced by RNA from bovine ligament. Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact