Geert Jan Sterk

1.2k citations

41 papers · 806 indexed · h-index 16

Organic Chemistry top 10%
- Synthesis and Biological Evaluation 10
- Synthesis and Catalytic Reactions 4
Parasitology top 10%
Molecular Biology
- Phosphodiesterase function and regulation 12
- Receptor Mechanisms and Signaling 7
- Chemical Synthesis and Analysis 5
Immunology
Sensory Systems
Epidemiology
- Trypanosoma species research and implications 14
Public Health, Environmental and Occupational Health
- Research on Leishmaniasis Studies 10
Pharmacology
- Cholinesterase and Neurodegenerative Diseases 4

Co-authors: H. Timmerman Harro W. Wong Fong Sang Ruud Kraayenhof H. van der Goot Armin Hatzelmann Thomas Seebeck Richard M. Epand Hengming Ke
Cited by: Organic Chemistry Parasitology Molecular Biology
Journals: Biochemistry (1 paper)Journal of Medicinal Chemistry (8 papers)The Journal of Infectious Diseases (1 paper)
Partner nations: Netherlands Belgium United Kingdom

In The Last Decade

Geert Jan Sterk

40 papers receiving 789 citations

Peers

Countries citing papers authored by Geert Jan Sterk

Since Specialization

Citations

This map shows the geographic impact of Geert Jan Sterk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Geert Jan Sterk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Geert Jan Sterk more than expected).

Fields of papers citing papers by Geert Jan Sterk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Geert Jan Sterk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Geert Jan Sterk. The network helps show where Geert Jan Sterk may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Geert Jan Sterk, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Geert Jan Sterk Line = papers co-authored together Geert Jan Sterk links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study Bioorganic & Medicinal Chemistry ·Nace Zidar,Andrej Emanuel Cotman,Wessel Sinnige,Ondřej Benek,Michaela Barančoková,Anamarija Zega,Lucíja Peterlin Mašič,Tihomir Tomašič,Janez Ilaš,Sara R. Henderson,Julia E. A. Mundy,Anthony Maxwell,Clare E. M. Stevenson,David M. Lawson,Geert Jan Sterk,Rodrigo D. Tosso,Lucas Gutiérrez,Ricardo D. Enriz,D. Kikelj	2024	2
2	Lead Optimization of the 5-Phenylpyrazolopyrimidinone NPD-2975 toward Compounds with Improved Antitrypanosomal Efficacy Journal of Medicinal Chemistry ·Yang Zheng,Magali Van den Kerkhof,Mohamed Ibrahim,Iwan J. P. de Esch,Louis Maes,Geert Jan Sterk,Guy Caljon,Rob Leurs	2024	0
3	3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity International Journal for Parasitology Drugs and Drug Resistance ·Yang Zheng,Joachim Müller,Stefan Kunz,Marco Siderius,Louis Maes,Guy Caljon,Norbert Müller,Andrew Hemphill,Geert Jan Sterk,Rob Leurs	2022	9
4	Structure Activity Relationship of N-Substituted Phenyldihydropyrazolones Against Trypanosoma cruzi Amastigotes Frontiers in Chemistry ·Maarten Sijm,Louis Maes,Iwan J. P. de Esch,Guy Caljon,Geert Jan Sterk,Rob Leurs	2021	1
5	Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening Frontiers in Chemistry ·Erik de Heuvel,Albert J. Kooistra,Ewald Edink,Sjors van Klaveren,Jeffrey Stuijt,Tiffany van der Meer,Payman Sadek,Dorien Mabille,Guy Caljon,Louis Maes,Marco Siderius,Iwan J. P. de Esch,Geert Jan Sterk,Rob Leurs	2021	4
6	Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages PLoS neglected tropical diseases ·Jane C. Munday,Stefan Kunz,Titilola D. Kalejaiye,Marco Siderius,Susanne Schroeder,Daniel Paape,Ali H. Alghamdi,Zainab Abbasi,Sheng Xiang Huang,Anne-Marie Donachie,Samia William,Abdel Nasser A. Sabra,Geert Jan Sterk,Sanaa S. Botros,D. Brown,Charles S. Hoffman,Rob Leurs,Harry P. de Koning	2020	7
7	Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2) Bioorganic & Medicinal Chemistry ·Erik de Heuvel,Abhimanyu K. Singh,Pierre Boronat,Albert J. Kooistra,Tiffany van der Meer,Payman Sadek,Antoni R. Blaazer,Nathan C. Shaner,Daphne S. Bindels,Guy Caljon,Louis Maes,Geert Jan Sterk,Marco Siderius,Michael Oberholzer,Iwan J. P. de Esch,D. Brown,Rob Leurs	2019	15
8	The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target PLoS neglected tropical diseases ·Stefan Kunz,Vreni Balmer,Geert Jan Sterk,Michael P. Pollastri,Rob Leurs,Norbert Müller,Andrew Hemphill,Cornelia Spycher	2017	17
9	Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals Bioorganic & Medicinal Chemistry ·Johan J. N. Veerman,Toine van den Bergh,Kristina M. Orrling,Chimed Jansen,Paul Cos,Louis Maes,Eric Chatelain,Jean‐Robert Ioset,Ewald Edink,Hermann Tenor,Thomas Seebeck,Iwan J. P. de Esch,Rob Leurs,Geert Jan Sterk	2016	30
10	Conformationally restricted κ-opioid receptor agonists: Synthesis and pharmacological evaluation of diastereoisomeric and enantiomeric decahydroquinoxalines Bioorganic & Medicinal Chemistry Letters ·Peter Molenveld,Renaud Bouzanne des Mazery,Geert Jan Sterk,Roy P. M. Storcken,Reshma Autar,Bram van Oss,Richard N. S. van der Haas,Roland Fröhlich,Dirk Schepmann,Bernhard Wünsch,Michael Soeberdt	2015	9
11	Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits SLAS DISCOVERY ·Antoni R. Blaazer,Kristina M. Orrling,Anitha Shanmugham,Chimed Jansen,Louis Maes,Ewald Edink,Geert Jan Sterk,Marco Siderius,P. England,David Bailey,Iwan J. P. de Esch,Rob Leurs	2014	21
12	Phosphodiesterase Inhibitors as a New Generation of Antiprotozoan Drugs: Exploiting the Benefit of Enzymes that are Highly Conserved Between Host and Parasite Future Medicinal Chemistry ·Thomas Seebeck,Geert Jan Sterk,Hengming Ke	2011	49
13	Novel Selective PDE4 Inhibitors. 3. In Vivo Antiinflammatory Activity of a New Series of N-Substituted cis-Tetra- and cis-Hexahydrophthalazinones Journal of Medicinal Chemistry ·Margaretha Van der Mey,Hildegard Boss,Armin Hatzelmann,Ivonne J. Van der Laan,Geert Jan Sterk,H. Timmerman	2002	13
14	Fluorescent probes of membrane surface properties Biochimica et Biophysica Acta (BBA) - Biomembranes ·Richard M. Epand,Ruud Kraayenhof,Geert Jan Sterk,Harro W. Wong Fong Sang	1996	29
15	Monovalent cations differentially affect membrane surface properties and membrane curvature, as revealed by fluorescent probes and dynamic light scattering Biochimica et Biophysica Acta (BBA) - Biomembranes ·Ruud Kraayenhof,Geert Jan Sterk,Harro W. Wong Fong Sang,Klaas Krab,Richard M. Epand	1996	44
16	Synthesis and pharmacology of a series of new organic nitrate esters Pharmacy World & Science ·Jan Bron,Geert Jan Sterk,Jan F. van der Werf,H. Timmerman	1995	3
17	Probing biomembrane interfacial potential and pH profiles with a new type of float-like fluorophores positioned at varying distance from the membrane surface Biochemistry ·Ruud Kraayenhof,Geert Jan Sterk,Harro W. Wong Fong Sang	1993	67
18	Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles Journal of Medicinal Chemistry ·J. Ch. Eriks,H. van der Goot,Geert Jan Sterk,H. Timmerman	1992	78
19	4- or 5-(ω-Aminoalkyl)Thiazoles and Derivatives; New Selective H2-Receptor Agonists Birkhäuser Basel eBooks ·J. Ch. Eriks,Geert Jan Sterk,Ellen M. van der Aar,Suzanne Acker,H. van der Goot,H. Timmerman	1991	8
20	Studies on histaminergic compounds part v 1. vuf 8405 a potent and relatively easy accessible analogue of the h 2 agonist impromidine Geert Jan Sterk,H. Van-Der-Goot,H. Timmerman	1986	11

About Geert Jan Sterk

Geert Jan Sterk is a scholar working on Organic Chemistry, Small Animals and Biophysics, having authored 41 papers that have together received 806 indexed citations. Recurring topics across this work include Trypanosoma species research and implications (14 papers), Phosphodiesterase function and regulation (12 papers), Research on Leishmaniasis Studies (10 papers), Synthesis and Biological Evaluation (10 papers), Receptor Mechanisms and Signaling (7 papers), Chemical Synthesis and Analysis (5 papers), Synthesis and Catalytic Reactions (4 papers) and Cholinesterase and Neurodegenerative Diseases (4 papers). The work is most often cited by research in Organic Chemistry (314 citations), Parasitology (59 citations) and Molecular Biology (454 citations). Geert Jan Sterk has collaborated with scholars based in Netherlands, Belgium and United Kingdom. Frequent co-authors include H. Timmerman, Harro W. Wong Fong Sang, Ruud Kraayenhof, H. van der Goot, Armin Hatzelmann, Thomas Seebeck, Richard M. Epand, Hengming Ke, Hildegard Boss and Stefan Kunz. Their work appears in journals such as Biochemistry, Journal of Medicinal Chemistry and The Journal of Infectious Diseases.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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