Tadeusz Karcz

1.3k citations

63 papers · 959 indexed · h-index 20

Physiology top 2%
- Adenosine and Purinergic Signaling 20
Organic Chemistry top 5%
- Synthesis and Biological Evaluation 9
Biological Psychiatry
Cellular and Molecular Neuroscience top 10%
- Neuroscience and Neuropharmacology Research 9
Pharmacology top 10%
Immunology
- Mast cells and histamine 21
Molecular Biology
- Receptor Mechanisms and Signaling 18
- Phenothiazines and Benzothiazines Synthesis and Activities 13
- Pharmacological Receptor Mechanisms and Effects 11
- Chemical Synthesis and Analysis 7

Co-authors: Katarzyna Kieć‐Kononowicz Christa E. Müller Gniewomir Latacz Kamil Kuder Holger Stark Agata Siwek Agnieszka Olejarz‐Maciej Dorota Łażewska
Cited by: Physiology Organic Chemistry Biological Psychiatry
Journals: Journal of Clinical Investigation (1 paper)The Journal of Immunology (3 papers)Scientific Reports (1 paper)
Partner nations: Poland Germany United States

In The Last Decade

Tadeusz Karcz

59 papers receiving 949 citations

Peers

Countries citing papers authored by Tadeusz Karcz

Since Specialization

Citations

This map shows the geographic impact of Tadeusz Karcz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tadeusz Karcz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tadeusz Karcz more than expected).

Fields of papers citing papers by Tadeusz Karcz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tadeusz Karcz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tadeusz Karcz. The network helps show where Tadeusz Karcz may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Tadeusz Karcz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tadeusz Karcz Line = papers co-authored together Tadeusz Karcz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mitigating effects of H3 receptor antagonism on cerebellar autophagic pathways and behavioral phenotypes in BTBR T+ tf/J mouse model of autism spectrum disorder European Journal of Pharmacology ·Nermin Eissa,Petrilla Jayaprakash,Shouq Aljneibi,Aamal Ghazi Mahdi Al-Saadi,Shaikha Alzaabi,Dorota Łażewska,Tadeusz Karcz,Katarzyna Kieć‐Kononowicz,Bassem Sadek	2025	1
2	Synthesis, Experimental and Computational Evaluation of SERAAK1 as a 5-HT2A Receptor Ligand Molecules ·Agata Zięba,Ewa Kędzierska,Michał K. Jastrzębski,Tadeusz Karcz,Agnieszka Olejarz‐Maciej,Agata Sumara,Tuomo Laitinen,Tomasz M. Wróbel,Emilia Fornal,Marián Castro,Agnieszka A. Kaczor	2025	0
3	Targeting GABAergic Hypofunction Associated with Schizophrenia: Identification of α1β2γ2GABA-A Receptor Ligands with Neuroprotective and Antipsychotic Properties ACS Chemical Neuroscience ·Barbara Mordyl,Katarzyna Szafrańska,Joanna Śniecikowska,Jakub Jończyk,Bartłomiej Bieńko,Maria Mateos-Jimenez,Bartosz Wojdyła,Beata Gryzło,Monika Głuch‐Lutwin,Agata Siwek,Tadeusz Karcz,Karolina Słoczyńska,Elżbieta Pękala,Alicja Zakrzewska,Paweł Mierzejewski,Marcin Kołaczkowski,Monika Marcinkowska	2025	0
4	4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H₃ Receptors and Cholinesterases ACS Chemical Neuroscience ·Beata Michalska,Marek Dzięgielewski,Justyna Godyń,Tobias Werner,Marek Bajda,Tadeusz Karcz,Katarzyna Szczepańska,Holger Stark,Anna Więckowska,Krzysztof Walczyński,Marek Staszewski	2024	5
5	Guanidine Derivative ADS1017, a Potent Histamine H₃ Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile ACS Chemical Neuroscience ·Tadeusz Karcz,Katarzyna Szczepańska,Szczepan Mogilski,Aleksandra Moroz,Agnieszka Olejarz‐Maciej,Laura J. Humphrys,Steffen Pockes,Agata Siwek,Krzysztof Dubiel,Marek Staszewski,Thierry Calmels,Krzysztof Waczyński,Katarzyna Kieć‐Kononowicz	2024	1
6	AR71, Histamine H3 Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action) International Journal of Molecular Sciences ·Anna Stasiak,Ewelina Honkisz-Orzechowska,Z Gajda,W. C. Wagner,Katarzyna Popiołek-Barczyk,Kamil Kuder,Gniewomir Latacz,Michał Juszczak,Katarzyna Woźniak,Tadeusz Karcz,Katarzyna Szczepańska,Marta Jóźwiak-Bębenista,Katarzyna Kieć‐Kononowicz,Dorota Łażewska	2024	2
7	Dual 5-HT6/SERT ligands for mitigating neuropsychiatric symptoms of dementia exerting neuroprotection against amyloid-β toxicity, memory preservation, and antidepressant-like properties European Journal of Medicinal Chemistry ·Agata Siwek,Monika Marcinkowska,Monika Głuch‐Lutwin,Barbara Mordyl,Małgorzata Wolak,Magdalena Jastrzębska‐Więsek,Natalia Wilczyńska-Zawal,Elżbieta Wyska,Katarzyna Szafrańska,Tadeusz Karcz,Olga Ostrowska,Adam Bucki,Marcin Kołaczkowski	2024	2
8	Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo Molecules ·Agnieszka Olejarz‐Maciej,Szczepan Mogilski,Tadeusz Karcz,Tobias Werner,Katarzyna Kamińska,Jarosław Kupczyk,Ewelina Honkisz-Orzechowska,Gniewomir Latacz,Holger Stark,Katarzyna Kieć‐Kononowicz,Dorota Łażewska	2023	2
9	Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases Biomolecules ·Michał Załuski,Tadeusz Karcz,Anna Drabczyńska,Christin Vielmuth,Agnieszka Olejarz‐Maciej,Monika Głuch‐Lutwin,Barbara Mordyl,Agata Siwek,Grzegorz Satała,Christa E. Müller,Katarzyna Kieć‐Kononowicz	2023	7
10	Structure−Activity Relationship and Solubility Studies of N1‐Substituted Quinoxaline‐2,3‐diones as Kainate Receptor Antagonists ChemMedChem ·Paulina Chałupnik,Alina Vialko,Darryl S. Pickering,Birgitte Nielsen,Yasmin Bay,Anders S. Kristensen,Markus Hinkkanen,Katarzyna Szczepańska,Tadeusz Karcz,Gniewomir Latacz,Tommy N. Johansen,Ewa Szymańska	2023	3
11	Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y₁₄R Antagonist Journal of Medicinal Chemistry ·Zhiwei Wen,Veronica Salmaso,Kwan‐Young Jung,Ngan B. Phung,Varun Gopinatth,Qasim Shah,Alexandra T. Patterson,John C.R. Randle,Zhoumou Chen,Daniela Salvemini,David I. Lieberman,Gregory S. Whitehead,Tadeusz Karcz,Donald N. Cook,Kenneth A. Jacobson	2022	14
12	Hybrid molecules combining GABA-A and serotonin 5-HT6 receptors activity designed to tackle neuroinflammation associated with depression European Journal of Medicinal Chemistry ·Monika Marcinkowska,Barbara Mordyl,Nikola Fajkis-Zajączkowska,Agata Siwek,Tadeusz Karcz,Alicja Gawalska,Adam Bucki,Paweł Żmudzki,Anna Partyka,Magdalena Jastrzębska‐Więsek,Bartosz Pomierny,Maria Walczak,Magdalena Smolik,Karolina Pytka,Kamil Mika,Magdalena Kotańska,Marcin Kołaczkowski	2022	10
13	Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors International Journal of Molecular Sciences ·Dorota Łażewska,Agnieszka Olejarz‐Maciej,David Reiner‐Link,Maria Kaleta,Gniewomir Latacz,Małgorzata Zygmunt,Agata Doroż-Płonka,Tadeusz Karcz,Annika Frank,Holger Stark,Katarzyna Kieć‐Kononowicz	2020	16
14	Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent European Journal of Medicinal Chemistry ·Katarzyna Szczepańska,Steffen Pockes,Sabina Podlewska,Carina Höring,Kamil Mika,Gniewomir Latacz,Marek Bednarski,Agata Siwek,Tadeusz Karcz,Martin Nagl,Merlin Bresinsky,Denise Mönnich,Ulla Seibel,Kamil Kuder,Magdalena Kotańska,Holger Stark,Sigurd Elz,Katarzyna Kieć‐Kononowicz	2020	13
15	Design, synthesis, andin vitroandin vivocharacterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H₃receptor antagonists MedChemComm ·Marek Staszewski,Anna Stasiak,Tadeusz Karcz,Daniel A. McNaught-Flores,W. A. Fogel,Katarzyna Kieć‐Kononowicz,Rob Leurs,Krzysztof Walczyński	2019	5
16	Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies Bioorganic & Medicinal Chemistry ·Michał Załuski,Jakub Schabikowski,Miriam Schlenk,Agnieszka Olejarz‐Maciej,Bartłomiej Kubas,Tadeusz Karcz,Kamil Kuder,Gniewomir Latacz,Małgorzata Zygmunt,David Synak,Sonja Hinz,Christa E. Müller,Katarzyna Kieć‐Kononowicz	2019	22
17	Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates Bioorganic Chemistry ·Barbara Kaproń,Jarogniew J. Łuszczki,Agata Siwek,Tadeusz Karcz,Gabriel Nowak,Mirosław Zagaja,Marta Andres‐Mach,Anna Stasiłowicz-Krzemień,Judyta Cielecka‐Piontek,Janusz Kocki,Tomasz Plech	2019	29
18	Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands European Journal of Medicinal Chemistry ·Katarzyna Szczepańska,Tadeusz Karcz,Szczepan Mogilski,Agata Siwek,Kamil Kuder,Gniewomir Latacz,Monika Kubacka,Stefanie Hagenow,Annamaria Lubelska,Agnieszka Olejarz‐Maciej,Magdalena Kotańska,Bassem Sadek,Holger Stark,Katarzyna Kieć‐Kononowicz	2018	26
19	Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate International Journal of Medical Sciences ·Barbara Kaproń,Jarogniew J. Łuszczki,Agata Paneth,Monika Wujec,Agata Siwek,Tadeusz Karcz,Barbara Mordyl,Monika Głuch‐Lutwin,Anna Gryboś,Gabriel Nowak,Karolina Pająk,Krzysztof Jóźwiak,Adam Tomczykowski,Tomasz Plech	2017	18
20	Design, synthesis, and biological evaluation of fluorinated imidazo[1,2- a ]pyridine derivatives with potential antipsychotic activity European Journal of Medicinal Chemistry ·Monika Marcinkowska,Marcin Kołaczkowski,Krzysztof Kamiński,Adam Bucki,Maciej Pawłowski,Agata Siwek,Tadeusz Karcz,Barbara Mordyl,Gabriela Starowicz,Paulina Kubowicz,Elżbieta Pękala,Anna Wesołowska,Jerzy Samochowiec,Paweł Mierzejewski,Przemysław Bieńkowski	2016	30

About Tadeusz Karcz

Tadeusz Karcz is a scholar working on Physiology, Biological Psychiatry and Immunology, having authored 63 papers that have together received 959 indexed citations. Recurring topics across this work include Mast cells and histamine (21 papers), Adenosine and Purinergic Signaling (20 papers), Receptor Mechanisms and Signaling (18 papers), Phenothiazines and Benzothiazines Synthesis and Activities (13 papers), Pharmacological Receptor Mechanisms and Effects (11 papers), Synthesis and Biological Evaluation (9 papers), Neuroscience and Neuropharmacology Research (9 papers) and Chemical Synthesis and Analysis (7 papers). The work is most often cited by research in Physiology (169 citations), Organic Chemistry (339 citations) and Biological Psychiatry (27 citations). Tadeusz Karcz has collaborated with scholars based in Poland, Germany and United States. Frequent co-authors include Katarzyna Kieć‐Kononowicz, Christa E. Müller, Gniewomir Latacz, Kamil Kuder, Holger Stark, Agata Siwek, Agnieszka Olejarz‐Maciej, Dorota Łażewska, Sonja Hinz and J. Karolak‐Wojciechowska. Their work appears in journals such as Journal of Clinical Investigation, The Journal of Immunology and Scientific Reports.

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