Rena G. Lapidus

6.4k total citations · 2 hit papers
99 papers, 4.9k citations indexed

About

Rena G. Lapidus is a scholar working on Molecular Biology, Oncology and Hematology. According to data from OpenAlex, Rena G. Lapidus has authored 99 papers receiving a total of 4.9k indexed citations (citations by other indexed papers that have themselves been cited), including 68 papers in Molecular Biology, 34 papers in Oncology and 22 papers in Hematology. Recurrent topics in Rena G. Lapidus's work include Acute Myeloid Leukemia Research (21 papers), Cancer therapeutics and mechanisms (10 papers) and Epigenetics and DNA Methylation (9 papers). Rena G. Lapidus is often cited by papers focused on Acute Myeloid Leukemia Research (21 papers), Cancer therapeutics and mechanisms (10 papers) and Epigenetics and DNA Methylation (9 papers). Rena G. Lapidus collaborates with scholars based in United States, Japan and Italy. Rena G. Lapidus's co-authors include Nancy E. Davidson, Stephen B. Baylin, James G. Herman, Jean‐Pierre J. Issa, Adrian Merlo, Li Mao, David Sidransky, Patricia M. Sokolove, Anne Ferguson and Sharyl J. Nass and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Rena G. Lapidus

97 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

1995 1.2k citations Rena G. Lapidus, Jean‐Pierre J. Issa et al. PubMed profile →
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.

1995 668 citations Rena G. Lapidus, Nancy E. Davidson et al. PubMed profile →

Peers

Rena G. Lapidus

ONCOL

GENET

PRM

Donald Ogilvie United Kingdom

Zhongmei Zhou China

Junichi Kurebayashi Japan

T.R. Jeffry Evans United Kingdom

Sarki A. Abdulkadir United States

Carlo Leonetti Italy

Hans Christian Reinhardt Germany

Hans Neubauer Germany

Debabrata Banerjee United States

David O. Azorsa United States

Donald Ogilvie United Kingdom

Rena G. Lapidus

2.6k ×0.8

1.3k ×0.8

ONCOL

501 ×0.7

859 ×1.4

GENET

625 ×1.1

PRM

Citations per year, relative to Rena G. Lapidus Rena G. Lapidus (= 1×) peers Donald Ogilvie

Countries citing papers authored by Rena G. Lapidus

Since Specialization

Citations

This map shows the geographic impact of Rena G. Lapidus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rena G. Lapidus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rena G. Lapidus more than expected).

Fields of papers citing papers by Rena G. Lapidus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rena G. Lapidus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rena G. Lapidus. The network helps show where Rena G. Lapidus may publish in the future.

Co-authorship network of co-authors of Rena G. Lapidus

This figure shows the co-authorship network connecting the top 25 collaborators of Rena G. Lapidus. A scholar is included among the top collaborators of Rena G. Lapidus based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rena G. Lapidus. Rena G. Lapidus is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bollino, Dominique, et al.. (2024). Dual targeting of glutamine and serine metabolism in acute myeloid leukemia. Frontiers in Oncology. 14. 1326754–1326754. 3 indexed citations

Duru, Nadire, Nisha R. Pawar, Erik W. Martin, et al.. (2022). Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases. Proceedings of the National Academy of Sciences. 119(28). e2201423119–e2201423119. 8 indexed citations

Yang, Zejia, Jipei Liao, Lisa M. Schumaker, et al.. (2022). Simultaneously targeting ErbB family kinases and PI3K in HPV-positive head and neck squamous cell carcinoma. Oral Oncology. 131. 105939–105939. 8 indexed citations

Kapadia, Bandish, Amol C. Shetty, Dominique Bollino, et al.. (2022). Translatome changes in acute myeloid leukemia cells post exposure to pegcrisantaspase and venetoclax. Experimental Hematology. 108. 55–63. 6 indexed citations

Bailey, Christopher M., Rena G. Lapidus, Sandrine Niyongere, et al.. (2021). PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition–Dependent GSK-3β–Mediated c-Myc and Pim-1 Proteasomal Degradation. Molecular Cancer Therapeutics. 20(4). 676–690. 17 indexed citations

Atanackovic, Djordje, Forat Lutfi, Diego de Miguel‐Pérez, et al.. (2021). Deep dissection of the antiviral immune profile of patients with COVID-19. Communications Biology. 4(1). 1389–1389. 6 indexed citations

Hankey, Kim G., Tim Luetkens, John C. McLenithan, et al.. (2021). Eight-Day Point of Care CAR T-Cell Manufacturing on Clinimacs Prodigy from Healthy Donors As a Proof-of-Concept Study. Blood. 138(Supplement 1). 2851–2851. 1 indexed citations

Emadi, Ashkan, Bandish Kapadia, Dominique Bollino, et al.. (2020). Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia. Leukemia. 35(7). 1907–1924. 23 indexed citations

Li, Zhipeng, Jipei Liao, Zejia Yang, et al.. (2018). Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer. British Journal of Cancer. 120(3). 306–316. 13 indexed citations

10.

Natarajan, Karthika, Rena G. Lapidus, Rossana Trotta, et al.. (2017). Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation. Clinical Cancer Research. 24(1). 234–247. 36 indexed citations

11.

Zhang, Yanting, Rena G. Lapidus, Peiyan Liu, et al.. (2016). Targeting IκB Kinase β/NF-κB Signaling in Human Prostate Cancer by a Novel IκB Kinase β Inhibitor CmpdA. Molecular Cancer Therapeutics. 15(7). 1504–1514. 32 indexed citations

12.

Xie, Min, Rena G. Lapidus, Mariola Sadowska, Martin J. Edelman, & Ramachandra S. Hosmane. (2016). Synthesis, anticancer activity, and SAR analyses of compounds containing the 5:7-fused 4,6,8-triaminoimidazo[4,5-e][1,3]diazepine ring system. Bioorganic & Medicinal Chemistry. 24(12). 2595–2602. 16 indexed citations

13.

Gojo, Ivana, Ming Tan, Hong‐Bin Fang, et al.. (2013). Translational Phase I Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytarabine and Etoposide in Patients with Relapsed, Refractory, or High-Risk Acute Myeloid Leukemia. Clinical Cancer Research. 19(7). 1838–1851. 40 indexed citations

14.

Wozniak, Krystyna M., K. Nomoto, Rena G. Lapidus, et al.. (2011). Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice. Cancer Research. 71(11). 3952–3962. 75 indexed citations

15.

Carozzi, Valentina, A Chiorazzi, A Canta, et al.. (2009). Glutamate Carboxypeptidase Inhibition Reduces the Severity of Chemotherapy-Induced Peripheral Neurotoxicity in Rat. Neurotoxicity Research. 17(4). 380–391. 57 indexed citations

16.

Lapidus, Rena G., Carol W. Tiffany, John T. Isaacs, & Barbara S. Slusher. (2000). Prostate-specific membrane antigen (PSMA) enzyme activity is elevated in prostate cancer cells. The Prostate. 45(4). 350–354. 107 indexed citations

17.

Tiffany, Carol W., et al.. (1999). Characterization of the enzymatic activity of PSM: Comparison with brain NAALADase. The Prostate. 39(1). 28–35. 75 indexed citations

18.

Ferguson, Anne, Rena G. Lapidus, & Nancy E. Davidson. (1998). The regulation of estrogen receptor expression and function in human breast cancer. Cancer treatment and research. 94. 255–278. 9 indexed citations

19.

Lapidus, Rena G., Anne Ferguson, Yvonne Ottaviano, et al.. (1996). Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.. PubMed. 2(5). 805–10. 203 indexed citations

20.

Lapidus, Rena G., et al.. (1993). Use of Carboxyatractylate and Tight-Binding Inhibitor Theory to Determine the Concentration of Functional Mitochondrial Adenine Nucleotide Translocators in a Reconstituted System. Analytical Biochemistry. 210(1). 69–76. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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