Han C. Dan

3.7k total citations · 1 hit paper
25 papers, 2.2k citations indexed

About

Han C. Dan is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Han C. Dan has authored 25 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 11 papers in Cancer Research and 7 papers in Oncology. Recurrent topics in Han C. Dan's work include PI3K/AKT/mTOR signaling in cancer (9 papers), NF-κB Signaling Pathways (6 papers) and Cell death mechanisms and regulation (5 papers). Han C. Dan is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (9 papers), NF-κB Signaling Pathways (6 papers) and Cell death mechanisms and regulation (5 papers). Han C. Dan collaborates with scholars based in United States, China and Canada. Han C. Dan's co-authors include Albert S. Baldwin, Jin Q. Cheng, Patricia C. Cogswell, Jenny P.‐Y. Ting, Joseph A. Duncan, Mei Sun, Michael Fraser, Benjamin K. Tsang, Santo V. Nicosia and Saı̈d M. Sebti and has published in prestigious journals such as Journal of Biological Chemistry, Genes & Development and The Journal of Immunology.

In The Last Decade

Han C. Dan

25 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK

2008 508 citations Han C. Dan, Patricia C. Cogswell et al. Genes & Development profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Han C. Dan United States	22	1.5k	551	528	345	226	25	2.2k
Wenxiu Zhao China	28	1.4k 1.0×	596 1.1×	577 1.1×	462 1.3×	186 0.8×	67	2.4k
Juan‐José Ventura United States	22	1.8k 1.2×	521 0.9×	650 1.2×	472 1.4×	178 0.8×	34	2.6k
Lucia Magnelli Italy	27	1.4k 0.9×	647 1.2×	612 1.2×	337 1.0×	221 1.0×	83	2.7k
Susan E. Nozell United States	30	1.5k 1.0×	562 1.0×	791 1.5×	539 1.6×	141 0.6×	44	2.7k
J G Shelton United States	11	1.6k 1.1×	368 0.7×	593 1.1×	278 0.8×	156 0.7×	11	2.4k
Ju-Ming Wang Taiwan	28	1.3k 0.9×	499 0.9×	414 0.8×	455 1.3×	163 0.7×	44	2.1k
Qinghua Zeng China	23	1.5k 1.0×	468 0.8×	541 1.0×	260 0.8×	127 0.6×	63	2.4k
Can G. Pham United States	16	1.4k 1.0×	710 1.3×	369 0.7×	438 1.3×	241 1.1×	19	2.4k
Shaohui Cai China	26	1.3k 0.9×	472 0.9×	969 1.8×	688 2.0×	207 0.9×	65	2.5k
Qiang Zhou China	26	1.2k 0.8×	732 1.3×	524 1.0×	624 1.8×	409 1.8×	96	2.5k

Countries citing papers authored by Han C. Dan

Since Specialization

Citations

This map shows the geographic impact of Han C. Dan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Han C. Dan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Han C. Dan more than expected).

Fields of papers citing papers by Han C. Dan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Han C. Dan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Han C. Dan. The network helps show where Han C. Dan may publish in the future.

Co-authorship network of co-authors of Han C. Dan

This figure shows the co-authorship network connecting the top 25 collaborators of Han C. Dan. A scholar is included among the top collaborators of Han C. Dan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Han C. Dan. Han C. Dan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Liang, Chen, Lushun Yuan, Kaiyu Qian, et al.. (2018). Identification of Biomarkers Associated With Pathological Stage and Prognosis of Clear Cell Renal Cell Carcinoma by Co-expression Network Analysis. Frontiers in Physiology. 9. 399–399. 60 indexed citations

Yuan, Lushun, Guofeng Qian, Liang Chen, et al.. (2018). Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma. Frontiers in Genetics. 9. 328–328. 40 indexed citations

Chen, Liang, Yongwen Luo, Gang Wang, et al.. (2018). Prognostic value of a gene signature in clear cell renal cell carcinoma. Journal of Cellular Physiology. 234(7). 10324–10335. 23 indexed citations

Cao, Rui, Gang Wang, Kaiyu Qian, et al.. (2017). Silencing of HJURP induces dysregulation of cell cycle and ROS metabolism in bladder cancer cells via PPARγ-SIRT1 feedback loop. Journal of Cancer. 8(12). 2282–2295. 31 indexed citations

Cao, Rui, Gang Wang, Kaiyu Qian, et al.. (2017). TM4SF1 regulates apoptosis, cell cycle and ROS metabolism via the PPARγ-SIRT1 feedback loop in human bladder cancer cells. Cancer Letters. 414. 278–293. 69 indexed citations

Zhang, Yanting, Rena G. Lapidus, Peiyan Liu, et al.. (2016). Targeting IκB Kinase β/NF-κB Signaling in Human Prostate Cancer by a Novel IκB Kinase β Inhibitor CmpdA. Molecular Cancer Therapeutics. 15(7). 1504–1514. 32 indexed citations

Wang, Gang, Rui Cao, Yongzhi Wang, et al.. (2016). Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway. Scientific Reports. 6(1). 35783–35783. 103 indexed citations

Gao, Yu, Ronald B. Gartenhaus, Rena G. Lapidus, et al.. (2015). Differential IKK/NF-κB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells. Molecular Cancer Research. 13(12). 1602–1614. 21 indexed citations

Dan, Han C., Aaron Ebbs, Manolis Pasparakis, et al.. (2014). Akt-dependent Activation of mTORC1 Complex Involves Phosphorylation of mTOR (Mammalian Target of Rapamycin) by IκB Kinase α (IKKα). Journal of Biological Chemistry. 289(36). 25227–25240. 124 indexed citations

10.

Dan, Han C.. (2012). CT characteristics of primary mediastinal seminoma. 1 indexed citations

11.

Zhao, Yan, Yunqi Wang, Zengli Guo, et al.. (2012). Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway. The Journal of Immunology. 189(9). 4417–4425. 97 indexed citations

12.

Dan, Han C. & Albert S. Baldwin. (2008). Differential Involvement of IκB Kinases α and β in Cytokine- and Insulin-Induced Mammalian Target of Rapamycin Activation Determined by Akt. The Journal of Immunology. 180(11). 7582–7589. 63 indexed citations

13.

Dan, Han C., et al.. (2008). Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK. Genes & Development. 22(11). 1490–1500. 508 indexed citations breakdown →

14.

Dan, Han C., Mazhar Adli, & Albert S. Baldwin. (2007). Regulation of Mammalian Target of Rapamycin Activity in PTEN-Inactive Prostate Cancer Cells by IκB Kinase α. Cancer Research. 67(13). 6263–6269. 60 indexed citations

15.

Lee, Hansoo, Donghwa Kim, Han C. Dan, et al.. (2007). Identification and Characterization of Putative Tumor Suppressor NGB, a GTP-Binding Protein That Interacts with the Neurofibromatosis 2 Protein. Molecular and Cellular Biology. 27(6). 2103–2119. 23 indexed citations

16.

Yang, Lin, Han C. Dan, Mei Sun, et al.. (2004). Akt/Protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt. Cancer Research. 64(13). 4394–4399. 360 indexed citations

17.

Johnson, Nicole C, Han C. Dan, Jin Q. Cheng, & Patricia A. Kruk. (2004). BRCA1 185delAG mutation inhibits Akt-dependent, IAP-mediated caspase 3 inactivation in human ovarian surface epithelial cells. Experimental Cell Research. 298(1). 9–16. 24 indexed citations

18.

Dan, Han C., Kun Jiang, Domenico Coppola, et al.. (2004). Phosphatidylinositol-3-OH kinase/AKT and survivin pathways as critical targets for geranylgeranyltransferase I inhibitor-induced apoptosis. Oncogene. 23(3). 706–715. 79 indexed citations

19.

Fraser, Michael, Brendan M. Leung, Xiaojuan Yan, et al.. (2003). p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells.. PubMed. 63(21). 7081–8. 161 indexed citations

20.

Cheng, Jin Q., Xiuxian Jiang, Michael Fraser, et al.. (2002). Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway. Drug Resistance Updates. 5(3-4). 131–146. 124 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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