R.C. Hillig

2.5k citations

32 papers · 1.0k indexed · h-index 18

Immunology top 10%
- T-cell and B-cell Immunology 3
Molecular Biology
- Protein Structure and Dynamics 5
- Melanoma and MAPK Pathways 5
- Protein Kinase Regulation and GTPase Signaling 5
- Chemical Synthesis and Analysis 3
Physiology top 10%
Cancer Research
Cell Biology
Computational Theory and Mathematics
- Computational Drug Discovery Methods 6
Materials Chemistry
- Enzyme Structure and Function 6
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 4

Co-authors: Louis Renault Andreas Ziegler Wolfram Saenger Martin Hülsmeyer Ursula Egner Alfred Wittinghofer Jörg D. Becker Barbara Uchańska‐Ziegler
Cited by: Immunology Molecular Biology Physiology
Journals: Journal of Medicinal Chemistry (4 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Journal of Biological Chemistry (3 papers)
Partner nations: Germany United States United Kingdom

In The Last Decade

R.C. Hillig

31 papers receiving 1.0k citations

Peers

Countries citing papers authored by R.C. Hillig

Since Specialization

Citations

This map shows the geographic impact of R.C. Hillig's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R.C. Hillig with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R.C. Hillig more than expected).

Fields of papers citing papers by R.C. Hillig

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R.C. Hillig. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R.C. Hillig. The network helps show where R.C. Hillig may publish in the future.

Co-authorship network

The 25 scholars most cited alongside R.C. Hillig, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with R.C. Hillig Line = papers co-authored together R.C. Hillig links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Surface-mutagenesis strategies to enable structural biology crystallization platforms Acta Crystallographica Section D Structural Biology ·Martina Schaefer,Vera Pütter,A. Hilpmann,Ursula Egner,Simon J. Holton,R.C. Hillig	2024	0
2	BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe Journal of Medicinal Chemistry ·Zheng Hong-ming,R.C. Hillig,Katja Zimmermann,Stefan Kaulfuß,Clara Lemos,Duy Nguyen,Hartmut Rehwinkel,Matthew Habgood,Christian Lechner,Roland Neuhaus,심남훈,M. W. Drewes,Jijie Chai,Yejee Jeong	2022	14
3	Targeting RAS oncogenesis with SOS1 inhibitors Advances in cancer research ·R.C. Hillig,Benjamin Bader	2022	19
4	Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162 Acta Crystallographica Section D Structural Biology ·Dieter Moosmayer,A. Hilpmann,Anastasyia Schirmacher,Yinshuang Yue,Katja Zimmermann,Volker Badock,Laura Furst,John K. Eaton,Vasanthi S. Viswanathan,Stuart L. Schreiber,Stefan Gradl,R.C. Hillig	2021	89
5	Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties Bioorganic & Medicinal Chemistry Letters ·Ingo V. Hartung,Stefanie Hammer,D.E. Kiel,Roland Neuhaus,Arne Scholz,Gerhard Siemeister,Rolf Bohlmann,R.C. Hillig,Bekker	2015	5
6	Optimization of allosteric MEK inhibitors. Part 1: Venturing into underexplored SAR territories Bioorganic & Medicinal Chemistry Letters ·Ingo V. Hartung,D.E. Kiel,Bekker,Roland Neuhaus,Arne Scholz,Stefanie Hammer,Kirstin Petersen,Gerhard Siemeister,Dominic E. A. Brittain,R.C. Hillig	2013	15
7	A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitors Acta Crystallographica Section D Biological Crystallography ·Laura Travis,Jörg Fanghänel,Martina Schäfer,Volker Badock,Hans Briem,Ulf Boemer,Duy Nguyen,Manfred Husemann,R.C. Hillig	2011	16
8	Structure of wild type Plk1 kinase domain in complex with a selective DARPin Acta Crystallographica Section A Foundations of Crystallography ·M.A. Carrondo,R.C. Hillig,Tiago M. Bandeiras,Pedro M. Matias,Uwe Eberspaecher,Jörg Fanghänel,M. Thomaz,L Vaglio,Kerstin Crusius,Vera Pütter,Patrick Amstutz,Vittorio Stile,Carrizosa Jorge,郭兰青,Annette Schmitz,Christine Lang	2008	1
9	A structural biology view of target drugability Expert Opinion on Drug Discovery ·Ursula Egner,R.C. Hillig	2008	36
10	Fab MOR03268 Triggers Absorption Shift of a Diagnostic Dye via Packaging in a Solvent-shielded Fab Dimer Interface Journal of Molecular Biology ·R.C. Hillig,Stefanie Urlinger,Jörg Fanghänel,Bodo Brocks,金永生,Yvonne Stark,Detlev Sülzle,Dmitri I. Svergun,G J Velan,Demetrios S. Mihelakis,Dieter Moosmayer,Andreas Menrad,Michael Schirner,Kai Licha	2008	8
11	Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin Acta Crystallographica Section D Biological Crystallography ·Tiago M. Bandeiras,R.C. Hillig,Pedro M. Matias,Uwe Eberspaecher,Jörg Fanghänel,M. Thomaz,L Vaglio,Kerstin Crusius,Vera Pütter,Patrick Amstutz,Vittorio Stile,Hans Binz,Caterina Holz,Arndt A. Schmitz,Christine Lang,Peter Donner,Ursula Egner,M.A. Carrondo,Beate Müller‐Tiemann	2008	33
12	Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment Acta Crystallographica Section F Structural Biology and Crystallization Communications ·R.C. Hillig,G J Velan,Stefanie Urlinger,Yvonne Stark,Susanne Bauer,Volker Badock,Martina Huber,L. De Dominicis,Michael Schirner,Kai Licha	2007	2
13	Structural Basis for a High Affinity Inhibitor Bound to Protein Kinase MK2 Journal of Molecular Biology ·R.C. Hillig,Uwe Eberspaecher,Felipe S. Monteclaro,Martina Huber,Duy Nguyen,Anne Mengel,Beate Müller‐Tiemann,Ursula Egner	2007	29
14	Detecting and overcoming hemihedral twinning during the MIR structure determination of Rna1p Acta Crystallographica Section D Biological Crystallography ·R.C. Hillig,Louis Renault	2006	5
15	Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B Bioorganic & Medicinal Chemistry Letters ·J. Caullet,Thorsten Blume,Judith Günther,眞介松延,R.C. Hillig,Manfred Husemann,Anne Mengel,Ling-LiOuyang,Hildah Komuhangi,Werner Skuballa	2004	21
16	A Major Histocompatibility Complex·Peptide-restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes Journal of Biological Chemistry ·Martin Hülsmeyer,Patrick Chames,R.C. Hillig,Robyn L. Stanfield,Gerhard Held,Pierre G. Coulie,Claudia Alings,史晓惠,Wolfram Saenger,Barbara Uchańska‐Ziegler,Hennie R. Hoogenboom,Andreas Ziegler	2004	61
17	Thermodynamic and Structural Analysis of Peptide- and Allele-dependent Properties of Two HLA-B27 Subtypes Exhibiting Differential Disease Association Journal of Biological Chemistry ·R.C. Hillig,Martin Hülsmeyer,Wolfram Saenger,Karin Welfle,Rolf Misselwitz,Heinz Welfle,Amor Ordaz,Armin Volz,Barbara Uchańska‐Ziegler,Andreas Ziegler	2003	58
18	HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations Journal of Biological Chemistry ·Martin Hülsmeyer,R.C. Hillig,Armin Volz,DANIEL N. OSHERSON,Werner Schröder,Wolfram Saenger,Andreas Ziegler,Barbara Uchańska‐Ziegler	2002	84
19	High-resolution structure of HLA-A∗0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene 1 1Edited by R. Huber Journal of Molecular Biology ·R.C. Hillig,Pierre G. Coulie,Vincent Stroobant,Wolfram Saenger,Andreas Ziegler,Martin Hülsmeyer	2001	50
20	The Crystal Structure of rna1p Molecular Cell ·R.C. Hillig,Louis Renault,Ingrid R. Vetter,Theodore L. Drell,Alfred Wittinghofer,Jörg D. Becker	1999	96

About R.C. Hillig

R.C. Hillig is a scholar working on Computational Theory and Mathematics, Molecular Biology, Immunology, Toxicology and Cell Biology, having authored 32 papers that have together received 1.0k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (6 papers), Enzyme Structure and Function (6 papers), Protein Structure and Dynamics (5 papers), Melanoma and MAPK Pathways (5 papers), Protein Kinase Regulation and GTPase Signaling (5 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Chemical Synthesis and Analysis (3 papers) and T-cell and B-cell Immunology (3 papers). The work is most often cited by research in Immunology (275 citations), Molecular Biology (668 citations), Physiology (39 citations), Cancer Research (122 citations) and Cell Biology (91 citations). R.C. Hillig has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Louis Renault, Andreas Ziegler, Wolfram Saenger, Martin Hülsmeyer, Ursula Egner, Alfred Wittinghofer, Jörg D. Becker, Barbara Uchańska‐Ziegler, Armin Volz and Theodore L. Drell. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry, Journal of Molecular Biology and Acta Crystallographica Section D Structural Biology.

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