David A. Hildeman

13.4k citations

126 papers · 9.3k indexed · 2 hit papers · h-index 47

Impact in

Immunology top 0.2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
- Immune cells in cancer
Hematology top 1%
- Autoimmune and Inflammatory Disorders Research

Papers in

Immunology 102
- Immune Cell Function and Interaction 78
- T-cell and B-cell Immunology 50
- Immunotherapy and Immune Responses 28
- Immune Response and Inflammation 23
Transplantation 10
- Renal Transplantation Outcomes and Treatments 10

Co-authors: Philippa Marrack John W. Kappler Thomas C. Mitchell Michael B. Jordan Tom Mitchell Yanan Zhu Brian C. Schaefer T. Kent Teague
Journals: The Journal of Immunology (17 papers)Proceedings of the National Academy of Sciences (6 papers)Frontiers in Immunology (5 papers)American Journal of Transplantation (5 papers)Immunity (5 papers)
Partner nations: United States Australia Germany

In The Last Decade

David A. Hildeman

123 papers receiving 9.2k citations

Hit Papers

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Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling 2013 · 986 citations

Peers

Countries citing papers authored by David A. Hildeman

Since Specialization

Citations

This map shows the geographic impact of David A. Hildeman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Hildeman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Hildeman more than expected).

Fields of papers citing papers by David A. Hildeman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Hildeman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Hildeman. The network helps show where David A. Hildeman may publish in the future.

Co-authors

The 25 scholars most cited alongside David A. Hildeman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. Hildeman Line = papers co-authored together David A. Hildeman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Daytime SHP2 inhibitor dosing, when immune cell numbers are elevated, shrinks neurofibromas Life Science Alliance ·Niousha Ahmari, Kwangmin Choi, Jianqiang Wu, Tilat A. Rizvi, Ganesh Raj, Whony Rofianto, Mi‐Ok Kim, Xiyuan Zhang, Eva Dombi, Jack F. Shern, David A. Hildeman, Nancy Ratner	2025	0
2	Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance Science Advances ·Jay Pundavela, Anny Paola Meléndez Rizo, SHATAKSHI SRIVASTAVA, Tian-Fu Zhang, Liang Hu, Tilat A. Rizvi, Kwangmin Choi, David A. Hildeman, Nancy Ratner	2024	4
3	Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner Nutrition and Diabetes ·Maria E. Moreno‐Fernandez, L. Ya. Melkumova, Traci E. Stankiewicz, Jarren R. Oates, Abdulbaki Kınsün, Michelle S. M. A. Damen, Maha Almanan, Claire Chougnet, David A. Hildeman, Senad Divanovic	2021	13
4	IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression PMC ·Maha Almanan, Jana Raynor, 朱伟淑, Ryan Lobo, Shibabrata Mukherjee, Tian-Fu Zhang, Jennifer T Ingram, Ankur Singh Saini, Markus M. Xie, Theresa Alenghat, Sing Sing Way, George S. Deepe, Senad Divanovic, Harinder Singh, Emily R. Miraldi, Allan Zajac, Alexander L. Dent, Christoph Hölscher, Claire Chougnet, David A. Hildeman	2020	1
5	Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology Nature Communications ·Andrew R. Patterson, Mehari Endale, Kristin Lampe, Halil‐Ibrahim Aksoylar, Aron Flagg, James R. Woodgett, David A. Hildeman, Michael B. Jordan, Harinder Singh, Zeynep Yesim Kucuk, Jack Bleesing, Kasper Hoebe	2018	29
6	Tissue-specific control of latent CMV reactivation by regulatory T cells PLoS Pathogens ·Maha Almanan, Jana Raynor, Allyson Sholl, Karen Shebuski, Claire Chougnet, Rhonda D. Cardin, David A. Hildeman	2017	40
7	NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma PLoS ONE ·한경동, Suzanne C. Morris, Charles Perkins, Zhenqi Zhu, David A. Hildeman, Albert Bendelac, Fred D. Finkelman	2017	17
8	Temporal Expression of Bim Limits the Development of Agonist-Selected Thymocytes and Skews Their TCRβ Repertoire The Journal of Immunology ·J.Tomás Nogales Flores, Anke Fähnrich, C. Breeden, Carla M. Cuda, H. Leighton Grimes, Harris Perlman, Kathrin Kalies, David A. Hildeman	2016	15
9	VEGF Blockade Enables Oncolytic Cancer Virotherapy in Part by Modulating Intratumoral Myeloid Cells Molecular Therapy ·Mark A. Currier, Насонова Дарья Станиславовна, Allyson Sholl, سیدنصراله سجادی, Kelly Crawford, Senad Divanovic, Louis Boon, William F. Goins, Jason S. Frischer, Margaret H. Collins, Jennifer L. Leddon, William H. Baird, Amy Haseley, Keri A. Streby, Eni Kardi Wiyati, Folke große Deters, Rolf A. Brekken, Balveen Kaur, David A. Hildeman, Timothy P. Cripe	2013	34
10	BCL-2 allows effector and memory CD8+ T cells to tolerate higher expression of BIM (104.19) The Journal of Immunology ·Sema Kurtuluş, Pulak Tripathi, Maria E. Moreno‐Fernandez, Allyson Sholl, Jonathan D. Katz, Lyudmila N. Fedorchenko, David A. Hildeman	2011	2
11	IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis The Journal of Immunology ·Jacqueline Unsinger, 学谷本, Kevin R. Kasten, Шишкану Анастасия Николаевна, Eizo Watanabe, Jared T. Muenzer, Jacquelyn S. McDonough, 赖蓉, Thomas A. Ferguson, Jonathan E. McDunn, Michel Morre, David A. Hildeman, Charles C. Caldwell, Richard S. Hotchkiss	2010	240
12	Loss of T Cell and B Cell Quiescence Precedes the Onset of Microbial Flora-Dependent Wasting Disease and Intestinal Inflammation in Gimap5-Deficient Mice The Journal of Immunology ·Michael J. Barnes, Halil‐Ibrahim Aksoylar, Philippe Krebs, Tristan Bourdeau, Carrie Arnold, Yu Xia, Assajie Bandara, Isaac Engel, Sosathya Sovath, Kristin Lampe, Antonio López Gómez, Amy Saunders, Geoffrey W. Butcher, Mitchell Kronenberg, Kris A. Steinbrecher, David A. Hildeman, H. Leighton Grimes, Bruce Beutler, Kasper Hoebe	2010	50
13	Endogenously Produced IL-4 Nonredundantly Stimulates CD8+ T Cell Proliferation The Journal of Immunology ·Suzanne C. Morris, H. S. Gress, De’Broski R. Herbert, Charles Perkins, David A. Hildeman, Marat Khodoun, Fred D. Finkelman	2009	46
14	Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation The Journal of Immunology ·Celine S. Lages, Isabelle Suffia, Paula A. Velilla, Bin Huang, Gregg Warshaw, David A. Hildeman, Yasmine Belkaid, Claire Chougnet	2008	306
15	Bax does not have to adopt its final form to drive T cell death The Journal of Experimental Medicine ·Yanan Zhu, Xinqi Liu, David A. Hildeman, Fred W. Peyerl, Janice White, E Kushnir, John W. Kappler, Philippa Marrack	2006	14
16	Cutting Edge: Emergence of CD127high Functionally Competent Memory T Cells Is Compromised by High Viral Loads and Inadequate T Cell Help The Journal of Immunology ·Michael J. Fuller, David A. Hildeman, Steffanie Sabbaj, Dalia E. Gaddis, Anne E. Tebo, Shangdong Liang, Paul A. Goepfert, Allan Zajac	2005	118
17	Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells Proceedings of the National Academy of Sciences ·Yanan Zhu, Bradley Jay Swanson, Michael Wang, David A. Hildeman, Brian C. Schaefer, Xinqi Liu, Hiroyuki Suzuki, Katsuyoshi Mihara, John W. Kappler, Philippa Marrack	2004	104
18	CD40 Ligand Dysregulation in HIV Infection: HIV Glycoprotein 120 Inhibits Signaling Cascades Upstream of CD40 Ligand Transcription The Journal of Immunology ·Rui Zhang, Carl J. Fichtenbaum, David A. Hildeman, Jeffrey D. Lifson, Claire Chougnet	2004	39
19	T cell apoptosis and reactive oxygen species Journal of Clinical Investigation ·David A. Hildeman, Thomas C. Mitchell, John W. Kappler, Philippa Marrack	2003	127
20	Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis Immunity ·David A. Hildeman, Tom Mitchell, T. Kent Teague, Peter M. Henson, Brian J. Day, John W. Kappler, Philippa Marrack	1999	416

About David A. Hildeman

David A. Hildeman is a scholar working on Immunology, Transplantation, Neurology, Oncology and Hematology, having authored 126 papers that have together received 9.3k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (78 papers), T-cell and B-cell Immunology (50 papers), Immunotherapy and Immune Responses (28 papers), Immune Response and Inflammation (23 papers), Renal Transplantation Outcomes and Treatments (10 papers), Cell death mechanisms and regulation (10 papers), CAR-T cell therapy research (9 papers) and Neuroinflammation and Neurodegeneration Mechanisms (8 papers). The work is most often cited by research in Immunology (6.1k citations), Hematology (827 citations), Transplantation (147 citations), Oncology (1.4k citations) and Neurology (400 citations). David A. Hildeman has collaborated with scholars based in United States, Australia and Germany. Frequent co-authors include Philippa Marrack, John W. Kappler, Thomas C. Mitchell, Michael B. Jordan, Tom Mitchell, Yanan Zhu, Brian C. Schaefer, T. Kent Teague, Claire Chougnet and Pulak Tripathi. Their work appears in journals such as The Journal of Immunology, Proceedings of the National Academy of Sciences, Frontiers in Immunology, American Journal of Transplantation and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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