Philip J. Merta

1.2k citations

23 papers · 839 indexed · h-index 15

Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods 3
Molecular Biology
- Cancer therapeutics and mechanisms 7
- DNA Repair Mechanisms 6
- Biochemical and Molecular Research 2
Organic Chemistry top 10%
Oncology
- Cancer-related Molecular Pathways 9
- Cytokine Signaling Pathways and Interactions 3
Genetics
Cell Biology
- Microtubule and mitosis dynamics 4
Hematology
- Acute Myeloid Leukemia Research 2

Co-authors: Philip J. Hajduk Eric F. Johnson Niru B. Soni Lemma Kifle James T. Metz Zehan Chen Peter Kovar Lisa Hasvold
Cited by: Computational Theory and Mathematics Molecular Biology Organic Chemistry
Journals: Journal of Biological Chemistry (1 paper)PLoS ONE (1 paper)Cancer Research (1 paper)
Partner nations: United States United Kingdom Sweden

In The Last Decade

Philip J. Merta

23 papers receiving 807 citations

Peers

Countries citing papers authored by Philip J. Merta

Since Specialization

Citations

This map shows the geographic impact of Philip J. Merta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip J. Merta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip J. Merta more than expected).

Fields of papers citing papers by Philip J. Merta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip J. Merta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip J. Merta. The network helps show where Philip J. Merta may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Philip J. Merta, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Philip J. Merta Line = papers co-authored together Philip J. Merta links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol Journal of Biological Chemistry ·Eric R. Goedken,M.A. Argiriadi,David Banach,Bryan A. Fiamengo,Sage E. Foley,Kristine E. Frank,Jonathan S. George,Christopher M. Harris,Adrian D. Hobson,David C. Ihle,D.J. Marcotte,Philip J. Merta,Mark Michalak,Sara Murdock,Medha J. Tomlinson,Jeffrey Voss	2015	73
2	JAK2V617F Drives Mcl-1 Expression and Sensitizes Hematologic Cell Lines to Dual Inhibition of JAK2 and Bcl-xL PLoS ONE ·Jun Guo,Lisa Roberts,Zhui Chen,Philip J. Merta,Keith B. Glaser,O. Jameel Shah	2015	27
3	Pyrimidine-Based Tricyclic Molecules as Potent and Orally Efficacious Inhibitors of Wee1 Kinase ACS Medicinal Chemistry Letters ·Yunsong Tong,Maricel Torrent,Alan S. Florjancic,Kenneth D. Bromberg,Fritz G. Buchanan,Debra C. Ferguson,Eric F. Johnson,Loren Lasko,David Maag,Philip J. Merta,Amanda M. Olson,Donald J. Osterling,Nirupama B. Soni,Alexander R. Shoemaker,T.M. Penning	2014	18
4	Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195 ACS Medicinal Chemistry Letters ·Yunsong Tong,Kent D. Stewart,Alan S. Florjancic,John E. Harlan,Philip J. Merta,Magdalena Przytulinska,Nirupama B. Soni,Kerren K. Swinger,Haizhong Zhu,Eric F. Johnson,Alexander R. Shoemaker,Thomas D. Penning	2013	26
5	Design and synthesis of tricyclic cores for kinase inhibition Bioorganic & Medicinal Chemistry Letters ·Stacy Van Epps,Bryan A. Fiamengo,Jeremy J. Edmunds,Anna Ericsson,Kristine E. Frank,Michael Friedman,Dawn M. George,Jonathan S. George,Eric R. Goedken,Brian Kotecki,Gloria Martı́nez,Philip J. Merta,Michael Morytko,Shashank Shekhar,Barbara S. Skinner,Kent D. Stewart,Jeffrey Voss,Grier A. Wallace,Lu Wang,Lu Wang,Neil Wishart	2012	18
6	Therapeutic Implications for the Induced Levels of Chk1 in Myc-Expressing Cancer Cells Clinical Cancer Research ·Andreas Höglund,Lisa M. Nilsson,Somsundar Veppil Muralidharan,Lisa Hasvold,Philip J. Merta,Martina Rudelius,Viktoriya D. Nikolova,Ulrich Keller,Jonas A. Nilsson	2011	110
7	Navigating the kinome Nature Chemical Biology ·James T. Metz,Eric F. Johnson,Niru B. Soni,Philip J. Merta,Lemma Kifle,Philip J. Hajduk	2011	233
8	Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α Bioorganic & Medicinal Chemistry Letters ·Steven L. Swann,Philip J. Merta,Lemma Kifle,Duncan R. Groebe,Kathy Sarris,Philip J. Hajduk,Chaohong Sun	2010	12
9	Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Lisa Hasvold,Le Wang,Magdalena Przytulinska,Zhan Xiao,Zehan Chen,Wen‐Zhen Gu,Philip J. Merta,John Xue,Peter Kovar,Haiying Zhang,Chang Park,Thomas J. Sowin,Saul H. Rosenberg,Nan‐Horng Lin	2008	10
10	Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability Bioorganic & Medicinal Chemistry Letters ·Yunsong Tong,Magdalena Przytulinska,Zhi‐Fu Tao,Jennifer J. Bouska,Kent D. Stewart,Chang Park,Gaoquan Li,Akiyo Claiborne,Peter Kovar,Zehan Chen,Philip J. Merta,Mai-Ha Bui,Amanda M. Olson,Donald J. Osterling,Haiying Zhang,Hing L. Sham,Saul H. Rosenberg,Thomas J. Sowin,Nan‐Horng Lin	2007	5
11	Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Gaoquan Li,Zhi‐Fu Tao,Yunsong Tong,Magdalena Przytulinska,Peter Kovar,Philip J. Merta,Zehan Chen,Haiying Zhang,Thomas J. Sowin,Saul H. Rosenberg,Nan‐Horng Lin	2007	9
12	Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Zhi‐Fu Tao,Gaoquan Li,Yunsong Tong,Zehan Chen,Philip J. Merta,Peter Kovar,Haiying Zhang,Saul H. Rosenberg,Hing L. Sham,Thomas J. Sowin,Nan‐Horng Lin	2007	22
13	Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors Bioorganic & Medicinal Chemistry Letters ·Zhi‐Fu Tao,Gaoquan Li,Yunsong Tong,Kent D. Stewart,Zehan Chen,Mai-Ha Bui,Philip J. Merta,Chang Park,Peter Kovar,Haiying Zhang,Hing L. Sham,Saul H. Rosenberg,Thomas J. Sowin,Nan‐Horng Lin	2007	25
14	Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors Journal of Medicinal Chemistry ·Zhi‐Fu Tao,Le Wang,Kent D. Stewart,Zehan Chen,Wendy Gu,Mai-Ha Bui,Philip J. Merta,Haiying Zhang,Peter Kovar,Eric F. Johnson,Chang Park,Russell A. Judge,Saul H. Rosenberg,Thomas J. Sowin,Nan‐Horng Lin	2007	69
15	Novel Approach to Mapping of Resistance Mutations in Whole Genomes by Using Restriction Enzyme Modulation of Transformation Efficiency Antimicrobial Agents and Chemotherapy ·Claude G. Lerner,Stephan J. Kakavas,Christian Wagner,Richard T. Chang,Philip J. Merta,Xiaoan Ruan,Randy E. Metzger,Bruce A. Beutel	2005	8
16	A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth Molecular Cancer Therapeutics ·Zehan Chen,Philip J. Merta,Nan-Hong Lin,Stephen K. Tahir,Peter Kovar,Hing L. Sham,Haiying Zhang	2005	34
17	A Strategy for Discovery of Novel Broad-Spectrum Antibacterials Using a High-Throughput Streptococcus pneumoniae Transcription/Translation Screen SLAS DISCOVERY ·Steven Pratt,Caroline A. David,Candace Black‐Schaefer,Peter J. Dandliker,Xiaoling Xuei,Usha Warrior,David J. Burns,Ping Zhong,Zhensheng Cao,Anne Y. Saiki,Claude G. Lerner,Linda E. Chovan,Niru B. Soni,Angela M. Nilius,Frank L. Wagenaar,Philip J. Merta,Linda Traphagen,Bruce A. Beutel	2004	22
18	Synthesis and SAR evaluation of oxadiazolopyrazines as selective Haemophilus influenzae antibacterial agents Bioorganic & Medicinal Chemistry Letters ·Xenia Beebe,Angela M. Nilius,Philip J. Merta,Niru B. Soni,Mai H. Bui,Rolf Wagner,Bruce A. Beutel	2003	21
19	Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids Cancer Chemotherapy and Pharmacology ·Bonnie S. Glisson,Ann M. Killary,Philip J. Merta,Warren E. Ross,Jeanette Siciliano,Michael J. Siciliano	1992	5
20	Characterization of water in unfertilized and fertilized sea urchin eggs Journal of Cellular Physiology ·Philip J. Merta,Gary D. Fullerton,Ivan L. Cameron	1986	17

About Philip J. Merta

Philip J. Merta is a scholar working on Oncology, Molecular Medicine and Molecular Biology, having authored 23 papers that have together received 839 indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (9 papers), Cancer therapeutics and mechanisms (7 papers), DNA Repair Mechanisms (6 papers), Microtubule and mitosis dynamics (4 papers), Computational Drug Discovery Methods (3 papers), Cytokine Signaling Pathways and Interactions (3 papers), Acute Myeloid Leukemia Research (2 papers) and Biochemical and Molecular Research (2 papers). The work is most often cited by research in Computational Theory and Mathematics (294 citations), Molecular Biology (567 citations) and Organic Chemistry (207 citations). Philip J. Merta has collaborated with scholars based in United States, United Kingdom and Sweden. Frequent co-authors include Philip J. Hajduk, Eric F. Johnson, Niru B. Soni, Lemma Kifle, James T. Metz, Zehan Chen, Peter Kovar, Lisa Hasvold, Lisa M. Nilsson and Martina Rudelius. Their work appears in journals such as Journal of Biological Chemistry, PLoS ONE and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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