Ulrich Grädler

1.7k total citations
28 papers, 987 citations indexed

About

Ulrich Grädler is a scholar working on Molecular Biology, Organic Chemistry and Computational Theory and Mathematics. According to data from OpenAlex, Ulrich Grädler has authored 28 papers receiving a total of 987 indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 4 papers in Organic Chemistry and 4 papers in Computational Theory and Mathematics. Recurrent topics in Ulrich Grädler's work include Computational Drug Discovery Methods (4 papers), Heat shock proteins research (4 papers) and Click Chemistry and Applications (3 papers). Ulrich Grädler is often cited by papers focused on Computational Drug Discovery Methods (4 papers), Heat shock proteins research (4 papers) and Click Chemistry and Applications (3 papers). Ulrich Grädler collaborates with scholars based in Germany, United States and Portugal. Ulrich Grädler's co-authors include Djordje Müsil, Matthias Frech, Andree Blaukat, Dieter Dorsch, Hartmut E. Greiner, Hans‐Peter Buchstaller, Ulrich Pehl, Marta Amaral, G. Klebe and Timo Heinrich and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Molecular Biology and Cancer Research.

In The Last Decade

Ulrich Grädler

28 papers receiving 972 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Ulrich Grädler Germany 17 616 227 180 125 99 28 987
Albert Stewart United States 11 979 1.6× 93 0.4× 76 0.4× 383 3.1× 100 1.0× 16 1.3k
Richard M. Keenan United States 23 576 0.9× 72 0.3× 394 2.2× 175 1.4× 34 0.3× 39 1.4k
Kevin Kish United States 20 930 1.5× 209 0.9× 381 2.1× 265 2.1× 46 0.5× 38 2.0k
Kenji Morikami United States 14 768 1.2× 126 0.6× 366 2.0× 183 1.5× 103 1.0× 29 1.2k
Cristina Lewis United States 16 935 1.5× 53 0.2× 219 1.2× 319 2.6× 115 1.2× 26 1.4k
John S. Tokarski United States 23 776 1.3× 450 2.0× 690 3.8× 438 3.5× 103 1.0× 43 2.0k
Richard Sedrani Switzerland 16 783 1.3× 149 0.7× 343 1.9× 237 1.9× 26 0.3× 23 1.6k
Susan Pav United States 12 960 1.6× 298 1.3× 344 1.9× 251 2.0× 116 1.2× 16 1.4k
Joseph Schoepfer Switzerland 24 1.5k 2.5× 209 0.9× 532 3.0× 470 3.8× 107 1.1× 43 2.0k
Alfred P. Spada United States 22 664 1.1× 137 0.6× 789 4.4× 172 1.4× 56 0.6× 44 1.8k

Countries citing papers authored by Ulrich Grädler

Since Specialization
Citations

This map shows the geographic impact of Ulrich Grädler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ulrich Grädler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ulrich Grädler more than expected).

Fields of papers citing papers by Ulrich Grädler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ulrich Grädler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ulrich Grädler. The network helps show where Ulrich Grädler may publish in the future.

Co-authorship network of co-authors of Ulrich Grädler

This figure shows the co-authorship network connecting the top 25 collaborators of Ulrich Grädler. A scholar is included among the top collaborators of Ulrich Grädler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ulrich Grädler. Ulrich Grädler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Esdar, Christina, Nina Linde, Andreas Blum, et al.. (2025). M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer. Molecular Cancer Therapeutics. 24(7). 1040–1053. 1 indexed citations
2.
Dedden, Dirk, Elisabeth V. Schneider, Maren Thomsen, et al.. (2024). Cryo-EM Structures of CRAF2/14-3-32 and CRAF2/14-3-32/MEK12 Complexes. Journal of Molecular Biology. 436(6). 168483–168483. 4 indexed citations
3.
Manival, Xavier, Timo Heinrich, Ansgar Wegener, et al.. (2023). Extract2Chip—Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance. Biosensors. 13(10). 913–913. 3 indexed citations
4.
Grädler, Ulrich, Dániel Schwarz, Ansgar Wegener, et al.. (2023). Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding. Journal of Biological Chemistry. 299(11). 105328–105328. 2 indexed citations
5.
Lammens, Katja, J.D. Bartho, Ulrich Grädler, et al.. (2021). Molecular basis of human ATM kinase inhibition. Nature Structural & Molecular Biology. 28(10). 789–798. 41 indexed citations
6.
Grädler, Ulrich, Michael Busch, Birgitta Leuthner, et al.. (2020). Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorganic & Medicinal Chemistry Letters. 30(22). 127551–127551. 9 indexed citations
7.
Grädler, Ulrich, Dániel Schwarz, M. Blaesse, et al.. (2019). Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies. Bioorganic & Medicinal Chemistry Letters. 29(23). 126717–126717. 33 indexed citations
8.
Schuetz, Doris A., Lars Richter, Marta Amaral, et al.. (2018). Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors. Journal of Medicinal Chemistry. 61(10). 4397–4411. 42 indexed citations
9.
Kokh, Daria B., Marta Amaral, Joerg Bomke, et al.. (2018). Estimation of Drug-Target Residence Times by τ-Random Acceleration Molecular Dynamics Simulations. Journal of Chemical Theory and Computation. 14(7). 3859–3869. 183 indexed citations
10.
Merkul, Eugen, Thomas J. J. Müller, Christina Esdar, et al.. (2016). Discovery of novel 7-azaindoles as PDK1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 26(13). 3073–3080. 16 indexed citations
11.
Dorsch, Dieter, Oliver Schadt, Frank Stieber, et al.. (2015). Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 25(7). 1597–1602. 68 indexed citations
12.
Grädler, Ulrich, Paul Czodrowski, Markus Klein, et al.. (2014). Structure-based optimization of non-peptidic Cathepsin D inhibitors. Bioorganic & Medicinal Chemistry Letters. 24(17). 4141–4150. 21 indexed citations
13.
Bladt, Friedhelm, Manja Friese‐Hamim, Christine Knuehl, et al.. (2013). EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors. Clinical Cancer Research. 19(11). 2941–2951. 114 indexed citations
14.
Grädler, Ulrich, Jörg Bomke, Djordje Müsil, et al.. (2013). Fragment-based discovery of focal adhesion kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23(19). 5401–5409. 26 indexed citations
15.
Grädler, Ulrich, Dániel Schwarz, Djordje Müsil, et al.. (2012). Structural and Biophysical Characterization of the Syk Activation Switch. Journal of Molecular Biology. 425(2). 309–333. 64 indexed citations
16.
Buchstaller, Hans‐Peter, Hans‐Michael Eggenweiler, Christian Sirrenberg, et al.. (2012). Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90. Bioorganic & Medicinal Chemistry Letters. 22(13). 4396–4403. 14 indexed citations
17.
Merkul, Eugen, et al.. (2011). Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling–TMS-deprotection–CuAAC sequence. Organic & Biomolecular Chemistry. 9(14). 5129–5129. 33 indexed citations
18.
Grädler, Ulrich, Thomas Fuchß, Wolf‐Rüdiger Ulrich, et al.. (2011). Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. Bioorganic & Medicinal Chemistry Letters. 21(14). 4228–4232. 30 indexed citations
19.
Grädler, Ulrich, Hans‐Dieter Gerber, George A. Garcia, et al.. (2001). A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase11Edited by R. Huber. Journal of Molecular Biology. 306(3). 455–467. 54 indexed citations
20.
Grädler, Ulrich, Ralf Ficner, George A. Garcia, et al.. (1999). Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA‐guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity. FEBS Letters. 454(1-2). 142–146. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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