Brian S. J. Blagg

10.4k total citations · 1 hit paper
227 papers, 8.3k citations indexed

About

Brian S. J. Blagg is a scholar working on Molecular Biology, Computational Theory and Mathematics and Materials Chemistry. According to data from OpenAlex, Brian S. J. Blagg has authored 227 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 214 papers in Molecular Biology, 67 papers in Computational Theory and Mathematics and 29 papers in Materials Chemistry. Recurrent topics in Brian S. J. Blagg's work include Heat shock proteins research (175 papers), Computational Drug Discovery Methods (67 papers) and Protein Structure and Dynamics (39 papers). Brian S. J. Blagg is often cited by papers focused on Heat shock proteins research (175 papers), Computational Drug Discovery Methods (67 papers) and Protein Structure and Dynamics (39 papers). Brian S. J. Blagg collaborates with scholars based in United States, Italy and United Kingdom. Brian S. J. Blagg's co-authors include Huiping Zhao, Alison C. Donnelly, Laura B. Peterson, Joseph A. Burlison, Anuj Khandelwal, Robert L. Matts, Gary Brandt, George Vielhauer, M. Kyle Hadden and Rick T. Dobrowsky and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Brian S. J. Blagg

217 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors

2021 226 citations Rachel E. Davis, Brian S. J. Blagg et al. profile →

Peers

Brian S. J. Blagg

CTM

IMMUN

Asimul Islam India

Gerhard Wolber Germany

Jonathan B. Baell Australia

Edward G. Mimnaugh United States

Nadine Homeyer Germany

Andrew C. Wallace United States

Rituraj Purohit India

Chresten R. Søndergaard Ireland

Terrone L. Rosenberry United States

Christian Oefner Switzerland

Asimul Islam India

Brian S. J. Blagg

4.4k ×0.7

1.2k ×0.7

CTM

741 ×0.6

767 ×0.9

214 ×0.3

IMMUN

Citations per year, relative to Brian S. J. Blagg Brian S. J. Blagg (= 1×) peers Asimul Islam

Countries citing papers authored by Brian S. J. Blagg

Since Specialization

Citations

This map shows the geographic impact of Brian S. J. Blagg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian S. J. Blagg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian S. J. Blagg more than expected).

Fields of papers citing papers by Brian S. J. Blagg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian S. J. Blagg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian S. J. Blagg. The network helps show where Brian S. J. Blagg may publish in the future.

Co-authorship network of co-authors of Brian S. J. Blagg

This figure shows the co-authorship network connecting the top 25 collaborators of Brian S. J. Blagg. A scholar is included among the top collaborators of Brian S. J. Blagg based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian S. J. Blagg. Brian S. J. Blagg is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Blagg, Brian S. J., et al.. (2025). Engineered Age‐Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments. Advanced Healthcare Materials. 14(7). e2404461–e2404461. 4 indexed citations

Ali, Aktar, et al.. (2025). Integrative Multi-Omics Analyses Reveal Mechanisms of Resistance to Hsp90β-Selective Inhibition. Cancers. 17(21). 3488–3488.

Xu, Hao & Brian S. J. Blagg. (2025). Glucose-regulated protein 94 (Grp94/gp96) in viral pathogenesis: Insights into its role and therapeutic potentials. European Journal of Medicinal Chemistry. 292. 117713–117713. 2 indexed citations

Xu, Hao, et al.. (2024). Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorganic & Medicinal Chemistry Letters. 111. 129893–129893. 7 indexed citations

Subramanian, Chitra, et al.. (2024). The Investigation of Hsp90C‐Terminal Inhibitors Containing Amide Bioisosteres. ChemMedChem. 19(24). e202400418–e202400418.

Blagg, Brian S. J., et al.. (2024). The role of Aha1 in cancer and neurodegeneration. Frontiers in Molecular Neuroscience. 17. 1509280–1509280.

Ilnytska, Olga, et al.. (2024). Molecular determinants of phospholipid treatment to reduce intracellular cholesterol accumulation in NPC1 deficiency. Journal of Biological Chemistry. 300(11). 107889–107889.

Ashfeld, Brandon L., Paul Helquist, Olaf Wiest, et al.. (2024). Mutant induced neurons and humanized mice enable identification of Niemann-Pick type C1 proteostatic therapies. JCI Insight. 9(20).

Smith, Amanda, et al.. (2024). Anti-inflammatory activities of novel heat shock protein 90 isoform selective inhibitors in BV-2 microglial cells. Frontiers in Molecular Biosciences. 11. 1405339–1405339. 5 indexed citations

10.

Wu, Junmin, Mijoon Lee, Man Wang, et al.. (2024). Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer. Cancers. 16(15). 2714–2714. 2 indexed citations

11.

Tomašič, Tihomir, et al.. (2020). Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations. International Journal of Molecular Sciences. 21(18). 6898–6898. 29 indexed citations

12.

Lei, Wei, Natalie K. Barker, Sanket J. Mishra, et al.. (2020). Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway. Science Signaling. 13(630). 14 indexed citations

13.

Jayaraj, Abhilash, Vinay Kumar, Brian S. J. Blagg, et al.. (2019). Stimulation of heat shock protein 90 chaperone function through binding of a novobiocin analog KU-32. Journal of Biological Chemistry. 294(16). 6450–6467. 11 indexed citations

14.

Davis, Rachel E., et al.. (2018). Molecular insights into the interaction of Hsp90 with allosteric inhibitors targeting the C-terminal domain. MedChemComm. 9(8). 1323–1331. 16 indexed citations

15.

Forsberg, Leah K., et al.. (2018). Exploiting polarity and chirality to probe the Hsp90 C-terminus. Bioorganic & Medicinal Chemistry. 26(12). 3096–3110. 5 indexed citations

16.

Sheehan, Alice, Andrew E. Messer, Maria Papadaki, et al.. (2018). Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin. Frontiers in Physiology. 9. 243–243. 19 indexed citations

17.

Robinson, Paul, Xing Liu, Yinhua Zhang, et al.. (2016). Novel Potential Treatment of Familial Hypertrophic Cardiomyopathy with Analogues of the Green Tea Polyphenol Epigallocatechin-3-Gallate. Biophysical Journal. 110(3). 125a–125a. 4 indexed citations

18.

Brown, Douglas, Huiping Zhao, Bhaskar Reddy Kusuma, et al.. (2013). Development of a High-Throughput Screening Cancer Cell-Based Luciferase Refolding Assay for Identifying Hsp90 Inhibitors. Assay and Drug Development Technologies. 11(8). 478–488. 12 indexed citations

19.

Guarnieri, Michael T., Brian S. J. Blagg, & Rui Zhao. (2010). A High-Throughput TNP-ATP Displacement Assay for Screening Inhibitors of ATP-Binding in Bacterial Histidine Kinases. Assay and Drug Development Technologies. 9(2). 174–183. 22 indexed citations

20.

Blagg, Brian S. J., et al.. (2004). Design, Synthesis, and Evaluation of a Radicicol and Geldanamycin Chimera, Radamide. Organic Letters. 6(24). 4459–4462. 58 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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