Nobuo Shimma

3.7k total citations · 1 hit paper
56 papers, 3.0k citations indexed

About

Nobuo Shimma is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Nobuo Shimma has authored 56 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 20 papers in Organic Chemistry and 12 papers in Oncology. Recurrent topics in Nobuo Shimma's work include Cancer therapeutics and mechanisms (11 papers), Synthesis and Biological Evaluation (7 papers) and Antifungal resistance and susceptibility (7 papers). Nobuo Shimma is often cited by papers focused on Cancer therapeutics and mechanisms (11 papers), Synthesis and Biological Evaluation (7 papers) and Antifungal resistance and susceptibility (7 papers). Nobuo Shimma collaborates with scholars based in Japan, Switzerland and United States. Nobuo Shimma's co-authors include Hideo Ishitsuka, Isao UMEDA, Masanori Miwa, Masako Ura, Noriaki Sawada, M Nishida, T Ishikawa, Kazushige Mori, Yuko Aoki and Yasuhiko Shiratori and has published in prestigious journals such as Journal of Biological Chemistry, Cancer Research and Scientific Reports.

In The Last Decade

Nobuo Shimma

56 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

1998 1.0k citations Masanori Miwa, Masako Ura et al. profile →

Peers

Nobuo Shimma

ONCOL

EPIDE

PRM

László Őrfi Hungary

Naoyuki Kanzaki Japan

Marie Boyd United Kingdom

John K. Buolamwini United States

Curtis R. Chong United States

Jacqueline Plowman United States

Stefania Nobili Italy

Tanaji T. Talele United States

Howard Kendrick United Kingdom

Helmut Mett Switzerland

László Őrfi Hungary

Nobuo Shimma

1.0k ×1.0

ONCOL

1.6k ×1.6

539 ×0.7

230 ×0.7

EPIDE

254 ×0.8

PRM

Citations per year, relative to Nobuo Shimma Nobuo Shimma (= 1×) peers László Őrfi

Countries citing papers authored by Nobuo Shimma

Since Specialization

Citations

This map shows the geographic impact of Nobuo Shimma's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nobuo Shimma with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nobuo Shimma more than expected).

Fields of papers citing papers by Nobuo Shimma

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nobuo Shimma. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nobuo Shimma. The network helps show where Nobuo Shimma may publish in the future.

Co-authorship network of co-authors of Nobuo Shimma

This figure shows the co-authorship network connecting the top 25 collaborators of Nobuo Shimma. A scholar is included among the top collaborators of Nobuo Shimma based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nobuo Shimma. Nobuo Shimma is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ishii, Nobuya, Naoki Harada, Eric W. Joseph, et al.. (2013). Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity. Cancer Research. 73(13). 4050–4060. 128 indexed citations

Suda, Atsushi, Ken‐ichi Kawasaki, Susumu Komiyama, et al.. (2013). Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors. Bioorganic & Medicinal Chemistry. 22(2). 892–905. 36 indexed citations

Konishi, Hideyuki, Koichi Okamoto, Hitoshi Yoshino, et al.. (2012). An orally available, small-molecule interferon inhibits viral replication. Scientific Reports. 2(1). 259–259. 39 indexed citations

Suda, Atsushi, Hiroshi Koyano, Tadakatsu Hayase, et al.. (2011). Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(2). 1136–1141. 23 indexed citations

Hardegger, Leo A., Bernd Kuhn, Lilli Anselm, et al.. (2011). Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments. ChemMedChem. 6(11). 2048–2054. 105 indexed citations

Miura, Takaaki, Takaaki A. Fukami, Kiyoshi Hasegawa, et al.. (2011). Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design. Bioorganic & Medicinal Chemistry Letters. 21(19). 5778–5783. 28 indexed citations

Asoh, Kohsuke, Tatsuo Ohtsuka, Miyako Masubuchi, et al.. (2009). Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(6). 1753–1757. 39 indexed citations

Kohchi, Yasunori, Kazuo Hattori, Nobuhiro Oikawa, et al.. (2007). Design and synthesis of novel prodrugs of 2′-deoxy-2′-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues. Bioorganic & Medicinal Chemistry Letters. 17(8). 2241–2245. 5 indexed citations

Sogabe, Satoshi, Miyako Masubuchi, Kiyoaki Sakata, et al.. (2002). Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors. Chemistry & Biology. 9(10). 1119–1128. 107 indexed citations

10.

Ebiike, Hirosato, Miyako Masubuchi, Pingli Liu, et al.. (2002). Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2. Bioorganic & Medicinal Chemistry Letters. 12(4). 607–610. 66 indexed citations

11.

Murata, Takeshi, Masao Tsukazaki, Osamu Kondoh, et al.. (2001). Synthesis and Antifungal Activities of Novel 1,3-β-d-Glucan Synthase Inhibitors. Part 2. Bioorganic & Medicinal Chemistry Letters. 11(10). 1273–1276. 10 indexed citations

12.

Sudoh, Masayuki, Toshikazu Yamazaki, Mikio Taniguchi, et al.. (2000). Identification of a Novel Inhibitor Specific to the Fungal Chitin Synthase. Journal of Biological Chemistry. 275(42). 32901–32905. 42 indexed citations

13.

Taniguchi, Mikio, Isao UMEDA, Kazuo Hattori, et al.. (2000). Synthesis and structure–activity relationships of novel fungal chitin synthase inhibitors. Bioorganic & Medicinal Chemistry Letters. 10(13). 1459–1462. 35 indexed citations

14.

Ishitsuka, Hideo, Nobuo Shimma, & Ikuo Horii. (1999). Discovery and Development of Novel Anticancer Drug Capecitabine. YAKUGAKU ZASSHI. 119(12). 881–897. 19 indexed citations

15.

Tsukuda, Takuo, et al.. (1998). Synthesis of novel antifungal agents (2). Bioorganic & Medicinal Chemistry Letters. 8(14). 1825–1828. 2 indexed citations

16.

Kamiyama, Tsutomu, Nobuo Shimma, Tatsuo Ohtsuka, et al.. (1994). Cyclothialidine, a novel DNA gyrase inhibitor. II. Isolation, charactenzation and structure elucidation.. The Journal of Antibiotics. 47(1). 37–45. 18 indexed citations

17.

Ohtsuka, Tatsuo, et al.. (1993). Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. III. Structural elucidation.. The Journal of Antibiotics. 46(1). 18–24. 13 indexed citations

18.

Ohtsuka, Tatsuo, Noboru Nakayama, Yoshiko Itezono, et al.. (1993). Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. II. Isolation, characterization and biological activities.. The Journal of Antibiotics. 46(1). 11–17. 30 indexed citations

19.

Matsukuma, Shoko, Tatsuo Ohtsuka, Takashi Sano, et al.. (1992). A new series of natural antifungals that inhibit P450 lanosterol C-14 demethylase. I. Taxonomy, fermentation, isolation and structural elucidation.. The Journal of Antibiotics. 45(2). 151–159. 36 indexed citations

20.

Shimma, Nobuo, et al.. (1990). Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides. Antiviral Research. 13(2). 61–74. 49 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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