Hitoshi Iikura

1.3k citations

18 papers · 836 indexed · h-index 13

Co-authors: Eiichi Nakamura Masaya Sawamura Toshi Nagata Atsushi Hirai Seiji Mori Ulrich E. Hackler Yuko Aoki Nobuo Shimma
Topics: Fullerene Chemistry and Applications (6 papers)Melanoma and MAPK Pathways (5 papers)Protein Kinase Regulation and GTPase Signaling (3 papers)
Cited by: Organic Chemistry Materials Chemistry Inorganic Chemistry
Journals: Journal of the American Chemical Society Cancer Research Journal of Materials Chemistry
Partner nations: Japan United States South Korea

In The Last Decade

Hitoshi Iikura

18 papers receiving 817 citations

Peers

Countries citing papers authored by Hitoshi Iikura

Since Specialization

Citations

This map shows the geographic impact of Hitoshi Iikura's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hitoshi Iikura with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hitoshi Iikura more than expected).

Fields of papers citing papers by Hitoshi Iikura

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hitoshi Iikura. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hitoshi Iikura. The network helps show where Hitoshi Iikura may publish in the future.

Co-authorship network of co-authors of Hitoshi Iikura

This figure shows the co-authorship network connecting the top 25 collaborators of Hitoshi Iikura. A scholar is included among the top collaborators of Hitoshi Iikura based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hitoshi Iikura. Hitoshi Iikura is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

#	Work	Indexed citations
1	Abstract 1654: Anti-tumor activity of orally-available cyclic peptide LUNA18 through direct RAS inhibition in RAS-altered tumors 2024 ·Cancer Research ·Hitoshi Sase,(unknown),Yukako Tachibana,Masami Hasegawa,Toshihiko Fujii,(unknown),(unknown),Naoaki Murao,Shino Kuramoto,(unknown),Atsushi Ohta,(unknown),Takuya Shiraishi,Hitoshi Iikura,Takehisa Kitazawa,Hiroshi Tanaka	3
2	Abstract 1664: Combination of LUNA18, a novel RAS inhibitor, with KRAS G12C inhibitors augments anti-tumor activity via inhibition of MAPK pathway reactivation 2024 ·Cancer Research ·(unknown),Hitoshi Sase,Yukako Tachibana,Masami Hasegawa,Toshihiko Fujii,Shino Kuramoto,(unknown),Atsushi Ohta,(unknown),Takuya Shiraishi,Hitoshi Iikura,Takehisa Kitazawa,Hiroshi Tanaka	2
3	Broadly Applicable and Comprehensive Synthetic Method forN-Alkyl-Rich Drug-like Cyclic Peptides 2022 ·Journal of Medicinal Chemistry ·(unknown),Satoshi Hashimoto,(unknown),Minoru Tamiya,Tatsuya Kato,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Hitoshi Iikura	19
4	Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning 2014 ·ACS Medicinal Chemistry Letters ·Toshihiro Aoki,(unknown),Noriyuki Furuichi,(unknown),Fumio Watanabe,Masayuki Matsushita,Masahiro Sakaitani,Kenji Morikami,Kenji Takanashi,Naoki Harada,Yasushi Tomii,Koji Shiraki,Kentaro Furumoto,Mitsuyasu Tabo,(unknown),Kazutomo Ori,Yuko Aoki,Nobuo Shimma,Hitoshi Iikura	15
5	Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity 2013 ·Cancer Research ·Nobuya Ishii,Naoki Harada,Eric W. Joseph,Kazuhiro Ohara,Takaaki Miura,Hiroshi Sakamoto,Yutaka Matsuda,Yasushi Tomii,(unknown),Hitoshi Iikura,Toshihiro Aoki,Nobuo Shimma,Mikio Arisawa,Yoshihiro Sowa,Poulikos I. Poulikakos,Neal Rosen,Yuko Aoki,Toshiyuki Sakai	128
6	The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitors 2013 ·Bioorganic & Medicinal Chemistry Letters ·Toshihiro Aoki,(unknown),Noriyuki Furuichi,(unknown),Fumio Watanabe,Masayuki Matsushita,Masahiro Sakaitani,Kazutomo Ori,Kenji Takanashi,Naoki Harada,Yasushi Tomii,Mitsuyasu Tabo,(unknown),Yuko Aoki,Nobuo Shimma,Hitoshi Iikura	18
7	Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties 2013 ·ACS Medicinal Chemistry Letters ·(unknown),Noriyuki Furuichi,Toshihiro Aoki,Yoshiko Itezono,(unknown),(unknown),Fumio Watanabe,Masayuki Matsushita,Masahiro Sakaitani,Pil‐Su Ho,Kenji Takanashi,Naoki Harada,Yasushi Tomii,(unknown),Kazutomo Ori,Mitsuyasu Tabo,Yuko Aoki,Nobuo Shimma,Hitoshi Iikura	31
8	Abstract 2789: Discovery of a novel specific MEK and Raf inhibitor, CH5126766 (RO5126766), hit to lead study of a unique scaffold for kinase inhibitor to a clinical compound 2011 ·Cancer Research ·Hitoshi Iikura,Toshihiro Aoki,(unknown),Noriyuki Furuichi,Fumio Watanabe,(unknown),(unknown),Masayuki Matsushita,Nobuo Shimma,Naoki Harada,Yasushi Tomii,Yuko Aoki,Kenji Takanashi	1
9	Design and Synthesis of Peptidomimetic Factor VIIa Inhibitors 2010 ·Chemical and Pharmaceutical Bulletin ·Takuya Shiraishi,Shojiro Kadono,Masayuki Haramura,(unknown),Yoshiyuki Ono,Hitoshi Iikura,(unknown),(unknown),Kunihiro Hattori,Yoshiaki Watanabe,Akihisa Sakamoto,Kazutaka Yoshihashi,Takehisa Kitazawa,Keiko Esaki,Masateru Ohta,Haruhiko Sato,(unknown)	1
10	Structure-Based Drug Design of Peptide Mimetics Containing Large P3 Moieties as Inhibitors of Factor VIIa 2009 ·Letters in Drug Design & Discovery ·Takuya Shiraishi,Shojiro Kadono,Masayuki Haramura,(unknown),Yoshiyuki Ono,Hitoshi Iikura,(unknown),(unknown),Kunihiro Hattori,Yoshiaki Watanabe,Akihisa Sakamoto,Kazutaka Yoshihashi,Takehisa Kitazawa,Keiko Esaki,Masateru Ohta,Haruhiko Sato,(unknown)	2
11	Factor VIIa inhibitors: Target hopping in the serine protease family using X-ray structure determination 2008 ·Bioorganic & Medicinal Chemistry Letters ·Takuya Shiraishi,Shojiro Kadono,Masayuki Haramura,(unknown),Yoshiyuki Ono,Hitoshi Iikura,(unknown),(unknown),Kunihiro Hattori,Yoshiaki Watanabe,Akihisa Sakamoto,Kazutaka Yoshihashi,Takehisa Kitazawa,Keiko Esaki,Masateru Ohta,Haruhiko Sato,(unknown)	12
12	Cu(i)-mediated regioselective tri-addition of Grignard reagent to [70]fullerene. Synthesis of indenyl-type metal ligand embedded into graphitic structure 2002 ·Journal of Materials Chemistry ·Masaya Sawamura,Motoki Toganoh,Hitoshi Iikura,Yutaka Matsuo,Atsushi Hirai,Eiichi Nakamura	26
13	Single-step synthesis of pentaaryl-monohydro[60]fullerenes through fivefold addition of organocopper reagent to C60 2000 ·Journal of Organometallic Chemistry ·Masaya Sawamura,Hitoshi Iikura,(unknown),Ulrich E. Hackler,Eiichi Nakamura	58
14	Stepwise Synthesis of Fullerene Cyclopentadienide R₅C₆₀^- and Indenide R₃C₆₀^-. An Approach to Fully Unsymmetrically Substituted Derivatives 2000 ·Organic Letters ·Masaya Sawamura,Motoki Toganoh,Kazuhiro Suzuki,Atsushi Hirai,Hitoshi Iikura,Eiichi Nakamura	39
15	Structural Variation in Manganase Complexes: Synthesis and Characterization of Manganese Complexes from Carboxylate-containing Chelating Ligands 1998 ·Inorganic Chemistry ·Hitoshi Iikura,Toshi Nagata	94
16	Synthesis of π-Indenyl-type Fullerene Ligand and Its Metal Complexes via Quantitative Trisarylation of C₇₀ 1998 ·Journal of the American Chemical Society ·Masaya Sawamura,Hitoshi Iikura,Atsushi Hirai,Eiichi Nakamura	70
17	Endohedral Homoconjugation in Cyclopentadiene Embedded in C₆₀. Theoretical and Electrochemical Evidence 1997 ·The Journal of Organic Chemistry ·Hitoshi Iikura,Seiji Mori,Masaya Sawamura,Eiichi Nakamura	92
18	The First Pentahaptofullerene Metal Complexes 1996 ·Journal of the American Chemical Society ·Masaya Sawamura,Hitoshi Iikura,Eiichi Nakamura	225

About Hitoshi Iikura

Hitoshi Iikura is a scholar working on Organic Chemistry, Hematology and Genetics, having authored 18 papers that have together received 836 indexed citations. Recurring topics across this work include Fullerene Chemistry and Applications (6 papers), Melanoma and MAPK Pathways (5 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). The work is most often cited by research in Organic Chemistry (565 citations), Materials Chemistry (430 citations) and Inorganic Chemistry (98 citations). Hitoshi Iikura has collaborated with scholars based in Japan, United States and South Korea. Frequent co-authors include Eiichi Nakamura, Masaya Sawamura, Toshi Nagata, Atsushi Hirai, Seiji Mori, Ulrich E. Hackler, Yuko Aoki, Nobuo Shimma, Naoki Harada and Yasushi Tomii. Their work appears in journals such as Journal of the American Chemical Society, Cancer Research and Journal of Materials Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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