Takuo Tsukuda

1.6k citations

24 papers · 1.2k indexed · 1 hit paper · h-index 14

Molecular Biology top 10%
Pulmonary and Respiratory Medicine top 5%
Oncology top 5%
Organic Chemistry top 10%
Epidemiology

Co-authors: Hiroshi Sakamoto Yuko Aoki Toshiyuki Tsukaguchi Nobuhiro Oikawa Takamitsu Kobayashi Takaaki A. Fukami Nobuya Ishii Tatsushi Kodama
Topics: Cancer therapeutics and mechanisms (5 papers)Hepatitis C virus research (5 papers)Heat shock proteins research (5 papers)
Cited by: Oncology Pulmonary and Respiratory Medicine Hepatology
Journals: Gastroenterology Cancer Cell Scientific Reports
Partner nations: Japan United States United Kingdom

In The Last Decade

Takuo Tsukuda

24 papers receiving 1.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant

2011 508 citations Hiroshi Sakamoto, Toshiyuki Tsukaguchi et al. Cancer Cell profile →

Peers

Countries citing papers authored by Takuo Tsukuda

Since Specialization

Citations

This map shows the geographic impact of Takuo Tsukuda's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Takuo Tsukuda with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Takuo Tsukuda more than expected).

Fields of papers citing papers by Takuo Tsukuda

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Takuo Tsukuda. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Takuo Tsukuda. The network helps show where Takuo Tsukuda may publish in the future.

Co-authorship network of co-authors of Takuo Tsukuda

This figure shows the co-authorship network connecting the top 25 collaborators of Takuo Tsukuda. A scholar is included among the top collaborators of Takuo Tsukuda based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Takuo Tsukuda. Takuo Tsukuda is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents 2016 ·Bioorganic & Medicinal Chemistry ·Hatsuo Kawada,Hirosato Ebiike,Masao Tsukazaki,(unknown),(unknown),(unknown),Kenji Morikami,(unknown),Miyuki Yoshida,Kotaro Ogawa,Nobuo Shimma,Takuo Tsukuda,Jun Ohwada	6
2	Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability 2015 ·Bioorganic & Medicinal Chemistry ·Hatsuo Kawada,Hirosato Ebiike,Masao Tsukazaki,(unknown),(unknown),(unknown),Kenji Morikami,(unknown),Miyuki Yoshida,Kotaro Ogawa,(unknown),Takuo Tsukuda,Jun Ohwada	9
3	Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors 2013 ·Bioorganic & Medicinal Chemistry ·Atsushi Suda,Ken‐ichi Kawasaki,Susumu Komiyama,Yoshiaki Isshiki,(unknown),Sung‐Jin Kim,(unknown),Kiyoshi Hasegawa,Takaaki A. Fukami,Shigeo Sato,Takaaki Miura,Naomi Ono,Toshikazu Yamazaki,Ryoichi Saitoh,Nobuo Shimma,Yasuhiko Shiratori,Takuo Tsukuda	36
4	A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes 2013 ·Gastroenterology ·Asao Katsume,Yuko Tokunaga,Yuichi Hirata,Tsubasa Munakata,Makoto Saito,(unknown),Koichi Okamoto,(unknown),(unknown),Shin‐ichi Fujiwara,Takuo Tsukuda,Yuko Aoki,Klaus Klumpp,Kyoko Tsukiyama–Kohara,Ahmed Elgohary,Masayuki Sudoh,Michinori Kohara	32
5	Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non‐small‐cell lung cancer 2013 ·Cancer Science ·Naomi Ono,Toshikazu Yamazaki,Toshiyuki Tsukaguchi,Toshihiko Fujii,Kiyoaki Sakata,Atsushi Suda,Takuo Tsukuda,Toshiyuki Mio,Nobuya Ishii,Osamu Kondoh,Yuko Aoki	26
6	An orally available, small-molecule interferon inhibits viral replication 2012 ·Scientific Reports ·Hideyuki Konishi,Koichi Okamoto,(unknown),Hitoshi Yoshino,(unknown),(unknown),Yuichi Hirata,(unknown),Hiroshi Sakamoto,Natsuko Hada,Asao Katsume,Michinori Kohara,Kazumi Morikawa,Takuo Tsukuda,Nobuo Shimma,Graham R. Foster,William Alazawi,Yuko Aoki,Mikio Arisawa,Masayuki Sudoh	39
7	Enantioselective synthesis of derivatives and structure–activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent 2012 ·Bioorganic & Medicinal Chemistry Letters ·Ken‐ichi Kawasaki,Miyako Masubuchi,Tadakatsu Hayase,Susumu Komiyama,Fumio Watanabe,Hiroshi Fukuda,Takeshi Murata,(unknown),(unknown),Hidetoshi Shindoh,Hiroshi Sakamoto,(unknown),(unknown),Asao Katsume,Masahiro Aoki,Yuko Aoki,Nobuo Shimma,Masayuki Sudoh,Takuo Tsukuda	3
8	Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation 2012 ·Bioorganic & Medicinal Chemistry Letters ·Hatsuo Kawada,Hirosato Ebiike,Masao Tsukazaki,(unknown),Kenji Morikami,(unknown),Miyuki Yoshida,Kotaro Ogawa,Nobuo Shimma,Takuo Tsukuda,Jun Ohwada	13
9	Angiogenesis inhibitors identified by cell-based high-throughput screening: Synthesis, structure–activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation 2012 ·Bioorganic & Medicinal Chemistry ·(unknown),Atsushi Suda,Kohsuke Asoh,Takuo Tsukuda,Masami Hasegawa,Yasuko Sato,Kotaro Ogawa,Shino Kuramoto,Yuko Aoki,Nobuo Shimma,Tsutomu Ishikawa,Hiroshi Koyano	12
10	Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)‐overexpressing cancers 2011 ·Cancer Science ·Naomi Ono,Toshikazu Yamazaki,Yoshito Nakanishi,Toshihiko Fujii,Kiyoaki Sakata,Yukako Tachibana,Atsushi Suda,(unknown),Takaaki Miura,Shigeo Sato,Ryoichi Saitoh,(unknown),Takuo Tsukuda,Toshiyuki Mio,Nobuya Ishii,Osamu Kondoh,Yuko Aoki	21
11	Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors 2011 ·Bioorganic & Medicinal Chemistry Letters ·Atsushi Suda,Hiroshi Koyano,Tadakatsu Hayase,(unknown),Ken‐ichi Kawasaki,Susumu Komiyama,Kiyoshi Hasegawa,Takaaki A. Fukami,Shigeo Sato,Takaaki Miura,Naomi Ono,Toshikazu Yamazaki,Ryoichi Saitoh,Nobuo Shimma,Yasuhiko Shiratori,Takuo Tsukuda	23
12	CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutantbreakdown → 2011 ·Cancer Cell ·Hiroshi Sakamoto,Toshiyuki Tsukaguchi,(unknown),Tatsushi Kodama,Takamitsu Kobayashi,Takaaki A. Fukami,Nobuhiro Oikawa,Takuo Tsukuda,Nobuya Ishii,Yuko Aoki	508
13	Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Yoshiyuki Ono,Takashi Emura,Kohsuke Asoh,Noriyuki Furuichi,Toshiya Ito,Hatsuo Kawada,Shota Tanaka,Kenji Morikami,Toshiyuki Tsukaguchi,Hiroshi Sakamoto,Takuo Tsukuda,Nobuhiro Oikawa	27
14	Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design 2011 ·Bioorganic & Medicinal Chemistry Letters ·Takaaki Miura,Takaaki A. Fukami,Kiyoshi Hasegawa,Naomi Ono,Atsushi Suda,(unknown),(unknown),Sung‐Jin Kim,(unknown),Yuko Aoki,Nobuo Shimma,Takuo Tsukuda,Yasuhiko Shiratori	28
15	Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802) 2011 ·Bioorganic & Medicinal Chemistry ·(unknown),Kohsuke Asoh,Noriyuki Furuichi,Toshiya Ito,Hatsuo Kawada,(unknown),Jun Ohwada,(unknown),Takamitsu Kobayashi,Kenji Takanashi,Toshiyuki Tsukaguchi,Hiroshi Sakamoto,Takuo Tsukuda,Nobuhiro Oikawa	134
16	9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors 2011 ·Journal of Medicinal Chemistry ·(unknown),Takamitsu Kobayashi,Kohsuke Asoh,Noriyuki Furuichi,Toshiya Ito,Hatsuo Kawada,(unknown),Jun Ohwada,Kazuo Hattori,(unknown),(unknown),Min-Jeong Park,Kenji Takanashi,Toshiyuki Tsukaguchi,Hiroshi Sakamoto,Takuo Tsukuda,Nobuhiro Oikawa	61
17	Host sphingolipid biosynthesis as a target for hepatitis C virus therapy 2005 ·Nature Chemical Biology ·Hiroshi Sakamoto,Koichi Okamoto,Masahiro Aoki,Hideyuki Kato,Asao Katsume,(unknown),Takuo Tsukuda,Nobuo Shimma,Yuko Aoki,Mikio Arisawa,Michinori Kohara,Masayuki Sudoh	158
18	Synthesis of novel antifungal agents (2) 1998 ·Bioorganic & Medicinal Chemistry Letters ·Takuo Tsukuda,Masami Watanabe,(unknown),Kazuo Hattori,(unknown),Nobuo Shimma	2
19	Modeling, synthesis and biological activity of novel antifungal agents (1) 1998 ·Bioorganic & Medicinal Chemistry Letters ·Takuo Tsukuda,Yasuhiko Shiratori,(unknown),(unknown),Kazuo Hattori,(unknown),Nobuo Shimma	61
20	Synthesis of cyclohexyl analogs of restricticin 1994 ·Bioorganic & Medicinal Chemistry Letters ·Takuo Tsukuda,Masami Watanabe,(unknown),(unknown),Nobuo Shimma	5

About Takuo Tsukuda

Takuo Tsukuda is a scholar working on Hepatology, Biochemistry and Molecular Biology, having authored 24 papers that have together received 1.2k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (5 papers), Hepatitis C virus research (5 papers) and Heat shock proteins research (5 papers). The work is most often cited by research in Oncology (492 citations), Pulmonary and Respiratory Medicine (529 citations) and Hepatology (117 citations). Takuo Tsukuda has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Hiroshi Sakamoto, Yuko Aoki, Toshiyuki Tsukaguchi, Nobuhiro Oikawa, Takamitsu Kobayashi, Takaaki A. Fukami, Nobuya Ishii, Tatsushi Kodama, Nobuo Shimma and Masayuki Sudoh. Their work appears in journals such as Gastroenterology, Cancer Cell and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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