Takuo Tsukuda

1.6k total citations · 1 hit paper
24 papers, 1.2k citations indexed

About

Takuo Tsukuda is a scholar working on Molecular Biology, Hepatology and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Takuo Tsukuda has authored 24 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 5 papers in Hepatology and 4 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Takuo Tsukuda's work include Cancer therapeutics and mechanisms (5 papers), Hepatitis C virus research (5 papers) and Heat shock proteins research (5 papers). Takuo Tsukuda is often cited by papers focused on Cancer therapeutics and mechanisms (5 papers), Hepatitis C virus research (5 papers) and Heat shock proteins research (5 papers). Takuo Tsukuda collaborates with scholars based in Japan, United States and United Kingdom. Takuo Tsukuda's co-authors include Hiroshi Sakamoto, Yuko Aoki, Toshiyuki Tsukaguchi, Nobuhiro Oikawa, Takamitsu Kobayashi, Takaaki A. Fukami, Nobuya Ishii, Tatsushi Kodama, Nobuo Shimma and Masayuki Sudoh and has published in prestigious journals such as Gastroenterology, Cancer Cell and Scientific Reports.

In The Last Decade

Takuo Tsukuda

24 papers receiving 1.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant

2011 508 citations Hiroshi Sakamoto, Toshiyuki Tsukaguchi et al. Cancer Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Takuo Tsukuda Japan	14	705	529	492	252	119	24	1.2k
Gary Larson United States	21	404 0.6×	350 0.7×	220 0.4×	280 1.1×	145 1.2×	60	1.3k
Wolfgang Seghezzi United States	24	1.5k 2.1×	241 0.5×	830 1.7×	186 0.7×	90 0.8×	34	2.3k
Takaaki A. Fukami Japan	12	564 0.8×	379 0.7×	366 0.7×	223 0.9×	38 0.3×	21	956
Marie-Christine Bissery France	17	641 0.9×	209 0.4×	641 1.3×	180 0.7×	54 0.5×	41	1.4k
Yasuhide Hirota Japan	13	1.1k 1.5×	111 0.2×	766 1.6×	197 0.8×	84 0.7×	21	1.5k
Kimberly A. Lee United States	15	1.8k 2.5×	183 0.3×	403 0.8×	68 0.3×	74 0.6×	19	2.4k
Junli Feng United States	11	600 0.9×	208 0.4×	257 0.5×	156 0.6×	31 0.3×	15	1.1k
A. Kathleen McClendon United States	17	904 1.3×	607 1.1×	937 1.9×	175 0.7×	42 0.4×	20	1.6k
Lian‐Sheng Li United States	19	1.4k 1.9×	241 0.5×	557 1.1×	314 1.2×	61 0.5×	49	1.9k
Carol Waghorne Canada	16	1.3k 1.9×	268 0.5×	528 1.1×	284 1.1×	52 0.4×	29	2.1k

Countries citing papers authored by Takuo Tsukuda

Since Specialization

Citations

This map shows the geographic impact of Takuo Tsukuda's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Takuo Tsukuda with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Takuo Tsukuda more than expected).

Fields of papers citing papers by Takuo Tsukuda

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Takuo Tsukuda. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Takuo Tsukuda. The network helps show where Takuo Tsukuda may publish in the future.

Co-authorship network of co-authors of Takuo Tsukuda

This figure shows the co-authorship network connecting the top 25 collaborators of Takuo Tsukuda. A scholar is included among the top collaborators of Takuo Tsukuda based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Takuo Tsukuda. Takuo Tsukuda is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kawada, Hatsuo, Hirosato Ebiike, Masao Tsukazaki, et al.. (2016). Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents. Bioorganic & Medicinal Chemistry. 24(13). 2897–2906. 6 indexed citations

Kawada, Hatsuo, Hirosato Ebiike, Masao Tsukazaki, et al.. (2015). Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability. Bioorganic & Medicinal Chemistry. 23(24). 7650–7660. 9 indexed citations

Suda, Atsushi, Ken‐ichi Kawasaki, Susumu Komiyama, et al.. (2013). Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors. Bioorganic & Medicinal Chemistry. 22(2). 892–905. 36 indexed citations

Katsume, Asao, Yuko Tokunaga, Yuichi Hirata, et al.. (2013). A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes. Gastroenterology. 145(4). 865–873. 32 indexed citations

Ono, Naomi, Toshikazu Yamazaki, Toshiyuki Tsukaguchi, et al.. (2013). Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non‐small‐cell lung cancer. Cancer Science. 104(10). 1346–1352. 26 indexed citations

Konishi, Hideyuki, Koichi Okamoto, Hitoshi Yoshino, et al.. (2012). An orally available, small-molecule interferon inhibits viral replication. Scientific Reports. 2(1). 259–259. 39 indexed citations

Kawasaki, Ken‐ichi, Miyako Masubuchi, Tadakatsu Hayase, et al.. (2012). Enantioselective synthesis of derivatives and structure–activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent. Bioorganic & Medicinal Chemistry Letters. 23(1). 336–339. 3 indexed citations

Kawada, Hatsuo, Hirosato Ebiike, Masao Tsukazaki, et al.. (2012). Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation. Bioorganic & Medicinal Chemistry Letters. 23(3). 673–678. 13 indexed citations

Suda, Atsushi, Kohsuke Asoh, Takuo Tsukuda, et al.. (2012). Angiogenesis inhibitors identified by cell-based high-throughput screening: Synthesis, structure–activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation. Bioorganic & Medicinal Chemistry. 20(4). 1442–1460. 12 indexed citations

10.

Ono, Naomi, Toshikazu Yamazaki, Yoshito Nakanishi, et al.. (2011). Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)‐overexpressing cancers. Cancer Science. 103(2). 342–349. 21 indexed citations

11.

Sakamoto, Hiroshi, Toshiyuki Tsukaguchi, Tatsushi Kodama, et al.. (2011). CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant. Cancer Cell. 19(5). 679–690. 508 indexed citations breakdown →

12.

Ono, Yoshiyuki, Takashi Emura, Kohsuke Asoh, et al.. (2011). Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(12). 3788–3793. 27 indexed citations

13.

Miura, Takaaki, Takaaki A. Fukami, Kiyoshi Hasegawa, et al.. (2011). Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design. Bioorganic & Medicinal Chemistry Letters. 21(19). 5778–5783. 28 indexed citations

14.

Suda, Atsushi, Hiroshi Koyano, Tadakatsu Hayase, et al.. (2011). Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(2). 1136–1141. 23 indexed citations

15.

Asoh, Kohsuke, Noriyuki Furuichi, Toshiya Ito, et al.. (2011). Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802). Bioorganic & Medicinal Chemistry. 20(3). 1271–1280. 134 indexed citations

16.

Sudoh, Masayuki, et al.. (2009). 947 A NEWLY SYNTHESIZED SERINE PALMITOYLTRANS- FERASE INHIBITOR, NA 808, HAS THE STRONG EFFECT TO HEPATITIS C VIRUS IN VITRO AND IN VIVO. Journal of Hepatology. 50. S344–S344. 1 indexed citations

17.

Sakamoto, Hiroshi, Koichi Okamoto, Masahiro Aoki, et al.. (2005). Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. Nature Chemical Biology. 1(6). 333–337. 158 indexed citations

18.

Tsukuda, Takuo, et al.. (1998). Synthesis of novel antifungal agents (2). Bioorganic & Medicinal Chemistry Letters. 8(14). 1825–1828. 2 indexed citations

19.

Tsukuda, Takuo, et al.. (1998). Modeling, synthesis and biological activity of novel antifungal agents (1). Bioorganic & Medicinal Chemistry Letters. 8(14). 1819–1824. 61 indexed citations

20.

Tsukuda, Takuo, et al.. (1993). Synthesis of restrictinol and 9,10,11,12-tetrahydro-7-desmethylrestricticin.. Chemical and Pharmaceutical Bulletin. 41(6). 1191–1193. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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