Hirosato Ebiike

1.3k total citations
31 papers, 1.0k citations indexed

About

Hirosato Ebiike is a scholar working on Molecular Biology, Organic Chemistry and Infectious Diseases. According to data from OpenAlex, Hirosato Ebiike has authored 31 papers receiving a total of 1.0k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 19 papers in Organic Chemistry and 4 papers in Infectious Diseases. Recurrent topics in Hirosato Ebiike's work include Asymmetric Synthesis and Catalysis (6 papers), PI3K/AKT/mTOR signaling in cancer (5 papers) and Chemical synthesis and alkaloids (5 papers). Hirosato Ebiike is often cited by papers focused on Asymmetric Synthesis and Catalysis (6 papers), PI3K/AKT/mTOR signaling in cancer (5 papers) and Chemical synthesis and alkaloids (5 papers). Hirosato Ebiike collaborates with scholars based in Japan, United States and Switzerland. Hirosato Ebiike's co-authors include Yuko Aoki, Kazuo Achiwa, Kiyoaki Sakata, Nobuo Shimma, Kenji Morikami, Toshihiko Fujii, Tatsuo Ohtsuka, Yasuhiko Shiratori, Miyako Masubuchi and Ken‐ichi Kawasaki and has published in prestigious journals such as Cancer Research, Clinical Cancer Research and Journal of Medicinal Chemistry.

In The Last Decade

Hirosato Ebiike

31 papers receiving 976 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Hirosato Ebiike Japan 14 605 480 120 105 81 31 1.0k
Wendell Wierenga United States 20 519 0.9× 487 1.0× 98 0.8× 98 0.9× 58 0.7× 53 1.1k
Francesca Blasco Switzerland 14 426 0.7× 222 0.5× 145 1.2× 36 0.3× 86 1.1× 20 897
Estela M.F. Muri Brazil 15 287 0.5× 368 0.8× 127 1.1× 63 0.6× 46 0.6× 50 757
Gregory A. Reichard United States 19 542 0.9× 601 1.3× 298 2.5× 126 1.2× 38 0.5× 37 1.4k
Kiyoaki Sakata United States 14 476 0.8× 320 0.7× 166 1.4× 102 1.0× 83 1.0× 19 865
Bryan Lanning United States 4 745 1.2× 480 1.0× 216 1.8× 44 0.4× 26 0.3× 8 982
Aranapakam M. Venkatesan United States 22 785 1.3× 523 1.1× 158 1.3× 183 1.7× 34 0.4× 40 1.4k
Guisen Zhao China 18 537 0.9× 490 1.0× 123 1.0× 62 0.6× 66 0.8× 58 1.1k
Gool F. Patel United States 9 476 0.8× 215 0.4× 110 0.9× 56 0.5× 53 0.7× 11 877
Saeed R. Khan United States 13 408 0.7× 500 1.0× 179 1.5× 70 0.7× 121 1.5× 32 951

Countries citing papers authored by Hirosato Ebiike

Since Specialization
Citations

This map shows the geographic impact of Hirosato Ebiike's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hirosato Ebiike with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hirosato Ebiike more than expected).

Fields of papers citing papers by Hirosato Ebiike

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hirosato Ebiike. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hirosato Ebiike. The network helps show where Hirosato Ebiike may publish in the future.

Co-authorship network of co-authors of Hirosato Ebiike

This figure shows the co-authorship network connecting the top 25 collaborators of Hirosato Ebiike. A scholar is included among the top collaborators of Hirosato Ebiike based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hirosato Ebiike. Hirosato Ebiike is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kawada, Hatsuo, Hirosato Ebiike, Masao Tsukazaki, et al.. (2016). Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents. Bioorganic & Medicinal Chemistry. 24(13). 2897–2906. 6 indexed citations
2.
Nakanishi, Yoshito, Toshiyuki Tsukaguchi, Toshihiko Fujii, et al.. (2014). The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH5183284/Debio 1347, a Novel Selective FGFR Inhibitor. Molecular Cancer Therapeutics. 13(11). 2547–2558. 101 indexed citations
3.
Kawada, Hatsuo, Hirosato Ebiike, Masao Tsukazaki, et al.. (2012). Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation. Bioorganic & Medicinal Chemistry Letters. 23(3). 673–678. 13 indexed citations
4.
Tanaka, Hiroshi, Miyuki Yoshida, Hiromi Tanimura, et al.. (2011). The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic PIK3CA Mutations. Clinical Cancer Research. 17(10). 3272–3281. 79 indexed citations
5.
Ohwada, Jun, Hirosato Ebiike, Hatsuo Kawada, et al.. (2011). Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799. Bioorganic & Medicinal Chemistry Letters. 21(6). 1767–1772. 56 indexed citations
6.
Asoh, Kohsuke, Tatsuo Ohtsuka, Miyako Masubuchi, et al.. (2009). Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(6). 1753–1757. 39 indexed citations
7.
Kawasaki, Ken‐ichi, Miyako Masubuchi, Kenji Morikami, et al.. (2003). Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3. Bioorganic & Medicinal Chemistry Letters. 13(1). 87–91. 90 indexed citations
8.
Sogabe, Satoshi, Miyako Masubuchi, Kiyoaki Sakata, et al.. (2002). Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors. Chemistry & Biology. 9(10). 1119–1128. 107 indexed citations
9.
Ebiike, Hirosato, Miyako Masubuchi, Pingli Liu, et al.. (2002). Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2. Bioorganic & Medicinal Chemistry Letters. 12(4). 607–610. 66 indexed citations
10.
Masubuchi, Miyako, Ken‐ichi Kawasaki, Hirosato Ebiike, et al.. (2001). Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N -myristoyltransferase. Part 1. Bioorganic & Medicinal Chemistry Letters. 11(14). 1833–1837. 103 indexed citations
12.
Kato, Tatsuhisa, et al.. (1996). Asymmetric Synthesis of (S)-(+)- and (R)-(-)-NZ-105 through the Modified Michaelis-Arbuzov Rearrangement as a Key Step.. Chemical and Pharmaceutical Bulletin. 44(5). 1132–1134. 10 indexed citations
13.
Ebiike, Hirosato & Kazuo Achiwa. (1994). Lipase-catalyzed asymmetric hydrolysis and regioselective bromination of 1,4-dihydropyridine. Synthesis of (R)-(=)-nilvadipine. Tetrahedron Asymmetry. 5(8). 1447–1450. 5 indexed citations
14.
Ebiike, Hirosato, et al.. (1994). Determination of the Absolute Configuration of Biologically Active (S)-(-)-NB 818 and Its Structural Correlation with the Stereoselectivity of the Channel Blocking Action.. Chemical and Pharmaceutical Bulletin. 42(9). 1968–1970. 3 indexed citations
15.
Achiwa, Kazuo, et al.. (1993). Enzyme-catalyzed Synthesis of Biologically Active (S)-Nilvadipine. Heterocycles. 35(2). 603–603. 9 indexed citations
16.
Ebiike, Hirosato, et al.. (1992). Enzymatic synthesis of optically active 2-carbamoyl-oxymethyl-1,4-dihydropyridines, (R)-(+)- and (S)-(−)-NB 818. Tetrahedron Asymmetry. 3(9). 1153–1156. 12 indexed citations
17.
Ebiike, Hirosato, Kazuaki Maruyama, & Kazuo Achiwa. (1992). Lipase-catalyzed enantioselective hydrolysis of 4-alkyl-1,4-dihydropyridine derivatives: synthesis of (+)- and (-)-methyl 2-(phenylthio)ethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate(PCA 4248).. Chemical and Pharmaceutical Bulletin. 40(4). 1083–1085. 12 indexed citations
18.
Hirose, Yoshihiko, et al.. (1992). Drastic solvent effect on lipase-catalyzed enantioselective hydrolysis of prochiral 1,4-dihydropyridines. Tetrahedron Letters. 33(47). 7157–7160. 78 indexed citations
19.
Murata, Masakazu, Hirosato Ebiike, & Kazuo Achiwa. (1991). Design of Lipase-catalyzed Asymmetric Reactions in Organic Solvents and Their Application to the Syhthesis of Optically Active Medicines.. Journal of Synthetic Organic Chemistry Japan. 49(12). 1127–1141. 4 indexed citations
20.
Kato, Yukio, Hirosato Ebiike, Kazuo Achiwa, et al.. (1990). Synthesis and inhibitory activity of isoindolinone derivatives on thromboxane A2 analog (U-46619)-induced vasocontraction.. Chemical and Pharmaceutical Bulletin. 38(7). 2060–2062. 46 indexed citations

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