Nigel J. Cairns

27.9k total citations · 6 hit papers
118 papers, 10.1k citations indexed

About

Nigel J. Cairns is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Nigel J. Cairns has authored 118 papers receiving a total of 10.1k indexed citations (citations by other indexed papers that have themselves been cited), including 82 papers in Physiology, 43 papers in Molecular Biology and 34 papers in Neurology. Recurrent topics in Nigel J. Cairns's work include Alzheimer's disease research and treatments (80 papers), Dementia and Cognitive Impairment Research (29 papers) and Parkinson's Disease Mechanisms and Treatments (25 papers). Nigel J. Cairns is often cited by papers focused on Alzheimer's disease research and treatments (80 papers), Dementia and Cognitive Impairment Research (29 papers) and Parkinson's Disease Mechanisms and Treatments (25 papers). Nigel J. Cairns collaborates with scholars based in United States, United Kingdom and Austria. Nigel J. Cairns's co-authors include David M. Holtzman, John C. Morris, P. L. Lantos, Gert Lübec, Richard A. Armstrong, Robert H. Baloh, Iga Wegorzewska, Shaughn Bell, Jonathan Mill and Peter Jenner and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Nigel J. Cairns

118 papers receiving 10.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

2017 823 citations Nigel J. Cairns et al. profile →
The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

2013 698 citations Michael W. Weiner, Dallas P. Veitch et al. Alzheimer s & Dementia profile →
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

2009 546 citations Nigel J. Cairns et al. profile →
Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

2016 535 citations Nigel J. Cairns, John C. Morris et al. profile →
Proteopathic tau seeding predicts tauopathy in vivo

2014 456 citations Brandon B. Holmes, Jennifer L. Furman et al. profile →
Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

2018 324 citations Dallas P. Veitch, Michael W. Weiner et al. Alzheimer s & Dementia profile →

Peers

Countries citing papers authored by Nigel J. Cairns

Since Specialization

Citations

This map shows the geographic impact of Nigel J. Cairns's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel J. Cairns with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel J. Cairns more than expected).

Fields of papers citing papers by Nigel J. Cairns

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel J. Cairns. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel J. Cairns. The network helps show where Nigel J. Cairns may publish in the future.

Co-authorship network of co-authors of Nigel J. Cairns

This figure shows the co-authorship network connecting the top 25 collaborators of Nigel J. Cairns. A scholar is included among the top collaborators of Nigel J. Cairns based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nigel J. Cairns. Nigel J. Cairns is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	VCP regulates early tau seed amplification via specific cofactors 2025 ·Molecular Neurodegeneration ·(unknown), (unknown), Clarissa Valdez, (unknown), (unknown), Anthony R. Vega, Omar M. Kashmer, (unknown), Andrew Lemoff, Nigel J. Cairns, Charles L. White, Marc I. Diamond	5
2	Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background 2021 ·Neuroscience Letters ·(unknown), Xuezhu Cai, (unknown), Stephani A. Davis, (unknown), Craig F. Ferris, Nigel J. Cairns, Michael A. Gitcho	3
3	Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics 2018 ·Journal of Biological Chemistry ·Tritia R. Yamasaki, Brandon B. Holmes, Jennifer L. Furman, Dhruva D. Dhavale, (unknown), (unknown), Nigel J. Cairns, Paul T. Kotzbauer, Marc I. Diamond	145
4	Cortical degeneration in chronic traumatic encephalopathy and Alzheimer’s disease neuropathologic change 2018 ·Neurological Sciences ·Richard A. Armstrong, Ann C. McKee, Thor D. Stein, Victor E. Alvarez, Nigel J. Cairns	11
5	Synthesis of Thiophene‐Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease 2017 ·Chemistry - A European Journal ·Hamid Shirani, Hanna Appelqvist, Marcus Bäck, Therése Klingstedt, Nigel J. Cairns, K. Peter R. Nilsson	36
6	Pathology of the Superior Colliculus in Chronic Traumatic Encephalopathy 2016 ·Optometry and Vision Science ·Richard A. Armstrong, Ann C. McKee, Nigel J. Cairns	11
7	Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies 2014 ·Current Neurology and Neuroscience Reports ·(unknown), John M. Ringman, Alison Goate, Colin L. Masters, Nigel J. Cairns, Adrian Danek, Neill R. Graff‐Radford, Bernardino Ghetti, John C. Morris	68
8	The Structural Basis for Optimal Performance of Oligothiophene‐Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates 2013 ·Chemistry - A European Journal ·Therése Klingstedt, Hamid Shirani, (unknown), Nigel J. Cairns, Christina J. Sigurdson, Michel Goedert, K. Peter R. Nilsson	94
9	The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception 2011 ·Alzheimer s & Dementia ·Michael W. Weiner, Dallas P. Veitch, Paul Aisen, Laurel Beckett, Nigel J. Cairns, Robert C. Green, Danielle Harvey, Clifford R. Jack, William J. Jagust, Enchi Liu, John C. Morris, Ronald C. Petersen, Andrew J. Saykin, Mark E. Schmidt, Leslie M. Shaw, Judith A. Siuciak, Holly Soares, Arthur W. Toga, John Q. Trojanowski, (unknown)	367
10	Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy 2006 ·Parkinsonism & Related Disorders ·Richard A. Armstrong, P. L. Lantos, Nigel J. Cairns	8
11	Overlap between neurodegenerative disorders 2005 ·Neuropathology ·Richard A. Armstrong, P. L. Lantos, Nigel J. Cairns	103
12	Sequence variants of IDE are associated with the extent of β-amyloid deposition in the Alzheimer's disease brain 2004 ·Neurobiology of Aging ·(unknown), Katy Chalmers, Niels Andreasen, Nenad Bogdanović, Gordon Wilcock, Nigel J. Cairns, Lars Feuk, Anthony J. Brookes, Seth Love, Kaj Blennow, Patrick G. Kehoe, Jonathan A. Prince	41
13	β-Secretase (BACE) and GSK-3 mRNA levels in Alzheimer’s disease 2003 ·Molecular Brain Research ·(unknown), David Virley, (unknown), (unknown), Stephen J. Moss, Anne W. Mudge, Elena Jazin, Nigel J. Cairns	55
14	A positive association between 5HT re-uptake binding sites and depression in dementia with Lewy bodies 2002 ·Journal of Affective Disorders ·Clive Ballard, Mary Ann Johnson, Margaret A. Piggott, Robert Perry, John T. O’Brien, Elise Rowan, Elaine Perry, P. L. Lantos, Nigel J. Cairns, Clive Holmes	24
15	The reduction of NADH 2001 ·Life Sciences ·Seong Hwan Kim, Roman Vlkolinský, Nigel J. Cairns, Michael Fountoulakis, Gert Lübec	125
16	Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome 1999 ·Neuroscience Letters ·Rainer Seidl, Susanne Fang-Kircher, Bettina Bidmon, Nigel J. Cairns, Gert Lübec	67
17	A Presenilin-1 Truncating Mutation Is Present in Two Cases with Autopsy-Confirmed Early-Onset Alzheimer Disease 1998 ·The American Journal of Human Genetics ·Carolyn Tysoe, John C. Whittaker, John H. Xuereb, Nigel J. Cairns, Marc Cruts, Christine Van Broeckhoven, Gordon Wilcock, David C. Rubinsztein	60
18	Apolipoprotein E e4 allele frequency in patients with multiple system atrophy 1997 ·Neuroscience Letters ·Nigel J. Cairns, Penny F Atkinson, Tibor Kovács, (unknown), Susan E. Daniel, P. L. Lantos	24
19	Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease 1997 ·Neuroscience Letters ·Carolyn Tysoe, John C. Whittaker, Nigel J. Cairns, Penny F Atkinson, Charles R. Harrington, John H. Xuereb, Gordon Wilcock, David C. Rubinsztein	31
20	Upregulation of the Anti-apoptotic Protein Bcl-2 May Be an Early Event in Neurodegeneration: Studies on Parkinson's and Incidental Lewy Body Disease 1997 ·Biochemical and Biophysical Research Communications ·(unknown), Susan E. Daniel, Nigel J. Cairns, Peter Jenner, Barry Halliwell	68

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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