John T. O’Brien

90.5k citations

796 papers · 46.0k indexed · 12 hit papers · h-index 110

Impact in

Psychiatry and Mental health top 0.01%
- Dementia and Cognitive Impairment Research
Neurology top 0.01%
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disease Mechanisms and Treatments
- Neurological disorders and treatments

Papers in

Psychiatry and Mental health 370
- Dementia and Cognitive Impairment Research 338
Neurology 149
- Parkinson's Disease Mechanisms and Treatments 135
- Neurological Disease Mechanisms and Treatments 85
- Neurological disorders and treatments 42
- Neuroinflammation and Neurodegeneration Mechanisms 40

Co-authors: Ian G. McKeith Alan Thomas Clive Ballard Michael Firbank David J. Burn Philip Scheltens Sean J. Colloby John‐Paul Taylor
Journals: International Journal of Geriatric Psychiatry (69 papers)Neurology (32 papers)International Psychogeriatrics (31 papers)Journal of Neurology Neurosurgery & Psychiatry (30 papers)Alzheimer s & Dementia (29 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

John T. O’Brien

772 papers receiving 44.6k citations

Hit Papers

12 papers align trajectories log scale

A synergistic core for human brain evolution and cognition 2022 · 146 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Nature Neuroscience
2022 Journal of Neurology Neurosurgery & Psychiatry
2019 European Journal of Epidemiology
2019 Ageing Research Reviews
2015 The Lancet
2014 Alzheimer Disease & Associated Disorders
2014 International Journal of Stroke
2013 Psychological Medicine
2013 Neurology
2007 The Lancet Neurology
2003 The Lancet Neurology
1989 Critical Reviews in Food Science and Nutrition

Peers

Countries citing papers authored by John T. O’Brien

Since Specialization

Citations

This map shows the geographic impact of John T. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John T. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John T. O’Brien more than expected).

Fields of papers citing papers by John T. O’Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John T. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John T. O’Brien. The network helps show where John T. O’Brien may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John T. O’Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John T. O’Brien Line = papers co-authored together John T. O’Brien links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Association between choroidal microvasculature in the eye and Alzheimer's disease risk in cognitively healthy mid‐life adults: A pilot study Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring ·Isabel Schumacher, A Leonhardt, Audrey Low, 悦子山元, Jungyuem Kim, Graciela Muñiz‐Terrera, Craig Ritchie, B. Dhillon, John T. O’Brien, Ana Júlia Corrêa Ferreira, Ian J. C. MacCormick, Tom MacGillivray	2025	2
2	C3 and C3a as indicators of complement dysregulation in tauopathies and FTLD-associated disorders Immunobiology ·J.S. Fernández Ruiz, R.H.O., MURRAY S. HOFFMAN, Zenailza Andrade de Brito, Molly G. Bright, Музыка Александр Евгеньевич, Novia Pitriana, Shu Yao Leong, Nilesh Singh, John T. O’Brien, James B. Rowe, B. Paul Morgan, Maura Malpetti, Wioleta M. Zelek	2025	0
3	The role of plasma inflammatory markers in late-life depression and conversion to dementia: a 3-year follow-up study Molecular Psychiatry ·Mariia Bocharova, Tom Borza, Leiv Otto Watne, Knut Engedal, John T. O’Brien, Geir Selbæk, 幸一郎齋藤, John Hodsoll, Allan H. Young, Dag Aarsland	2025	5
4	Plasma metabolites distinguish dementia with Lewy bodies from Alzheimer’s disease: a cross-sectional metabolomic analysis Frontiers in Aging Neuroscience ·Xiaobei Pan, Paul C. Donaghy, Gemma Roberts, Leonidas Chouliaras, John T. O’Brien, Alan Thomas, Amanda Heslegrave, Henrik Zetterberg, Bernadette McGuinness, Anthony Peter Passmore, Brian D. Green, Joseph Kane	2024	3
5	Outcomes of Patients With Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease at 3 and 5 Years After Diagnosis Neurology ·Calum A. Hamilton, Paul C. Donaghy, Rory Durcan, Jeneé L. Jacobs, Kirsty Olsen, Gemma Roberts, Michael Firbank, Louise Allan, John‐Paul Taylor, John T. O’Brien, Alan Thomas	2024	6
6	Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer’s disease Alzheimer s Research & Therapy ·Qing Qi, Dariusz Kucharski, Muhammad Ikhbar Ihsan, Karen Ritchie, Graciela Muñiz‐Terrera, Ivan Koychev, Paresh Malhotra, Siobhán Hutchinson, David Robinson, John T. O’Brien, Brian Lawlor, Lorina Naçi	2024	0
7	Differential Synaptic Loss in β‐Amyloid Positive Versus β‐Amyloid Negative Corticobasal Syndrome Movement Disorders ·Negin Holland, George Savulich, P. Simon Jones, Wangqianwei Yong, Duncan Street, Peter Swann, 寛治栗原, Maura Malpetti, Young T. Hong, Tim D. Fryer, Timothy Rittman, Eoin Mulroy, Franklin I. Aigbirhio, Kailash P. Bhatia, John T. O’Brien, James B. Rowe	2024	2
8	Entorhinal‐based path integration selectively predicts midlife risk of Alzheimer's disease Alzheimer s & Dementia ·Marco Cavallo, Отабек Назиржанович Насиров, Catarina Rua, Richard N. Henson, Cedric E. Williams, Neil Burgess, Christopher T. Rodgers, Matthias Stangl, Maria‐Eleni Dounavi, Ifa Dimiyati Khasanah, Ivan Koychev, Paresh Malhotra, Thomas Wolbers, Karen Ritchie, Craig Ritchie, John T. O’Brien, Li Su, Dennis Chan	2024	12
9	Investigating the brain’s neurochemical profile at midlife in relation to dementia risk factors Brain Communications ·Maria‐Eleni Dounavi, Lili Zhang, Iin Nuraeni, Sarah Gregory, Graciela Muñiz‐Terrera, Bajram Biqkaj, Marius Mada, Guy Williams, Brian Lawlor, Lorina Naçi, Clare E. Mackay, Ivan Koychev, Paresh Malhotra, Karen Ritchie, Craig Ritchie, Li Su, Adam Waldman, John T. O’Brien	2024	2
10	Longitudinal associations between β-amyloid and cortical thickness in mild cognitive impairment Brain Communications ·Elijah Mak, Liwen Zhang, Chin Hong Tan, Sunitha K.B, 于文明, Vanda Indhiaura Putririnda, L. Seitl, Eddie Chong, Xin Xu, Mary C. Stephenson, Narayanaswamy Venketasubramanian, Juan Zhou, John T. O’Brien, Christopher Chen	2023	5
11	Differential association of cerebral blood flow and anisocytosis in APOE ε4 carriers at midlife Journal of Cerebral Blood Flow & Metabolism ·Maria‐Eleni Dounavi, Elijah Mak, Peter Swann, Audrey Low, Graciela Muñiz‐Terrera, 虞平, Отабек Назиржанович Насиров, Guy Williams, Katie Wells, Brian Lawlor, Lorina Naçi, Paresh Malhotra, Clare E. Mackay, Ivan Koychev, Karen Ritchie, Li Su, Craig Ritchie, John T. O’Brien	2023	7
12	Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson’s disease Brain ·Nicola J. Ray, Rachael Lawson, Sarah L. Martin, Hilmar P. Sigurdsson, Joanna Wilson, Brook Galna, Sue Lord, Lisa Alcock, Gordon W. Duncan, Tien K. Khoo, John T. O’Brien, David J. Burn, John‐Paul Taylor, 憲弘地代, Maurizio Bergamino, Lynn Rochester, Alison J. Yarnall	2022	23
13	Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults Brain Communications ·Maria‐Eleni Dounavi, Audrey Low, Graciela Muñiz‐Terrera, Karen Ritchie, Craig Ritchie, Li Su, Hugh S. Markus, John T. O’Brien	2022	5
14	Molecular pathology and synaptic loss in primary tauopathies: an 18F-AV-1451 and 11C-UCB-J PET study Brain ·Negin Holland, Maura Malpetti, Timothy Rittman, Elijah Mak, Luca Passamonti, Sanne S. Kaalund, Frank H. Hezemans, P Simon Jones, George Savulich, Young T. Hong, Tim D. Fryer, Franklin I. Aigbirhio, John T. O’Brien, James B. Rowe	2021	27
15	Impaired sensory evidence accumulation and network function in Lewy body dementia Brain Communications ·Claire O’Callaghan, Michael Firbank, Alessandro Tomassini, Julia Schumacher, John T. O’Brien, John‐Paul Taylor	2021	7
16	Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study Journal of Cerebral Blood Flow & Metabolism ·Maria‐Eleni Dounavi, Audrey Low, Lili Zhang, Elijah Mak, Graciela Muñiz‐Terrera, Karen Ritchie, Craig Ritchie, Li Su, John T. O’Brien	2021	23
17	Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum Brain ·W Richard Bevan‐Jones, Thomas Cope, P. Simon Jones, Sanne S. Kaalund, Luca Passamonti, Kieren Allinson, Katarzyna Samulska, Young T. Hong, Tim D. Fryer, Robert Arnold, Jonathan Coles, Franklin I. Aigbirhio, A. J. Larner, Karalyn Patterson, John T. O’Brien, James B. Rowe	2020	70
18	Rates, risks and routes to reduce vascular dementia (R4vad), a UK-wide multicentre prospective observational cohort study of cognition after stroke: Protocol European Stroke Journal ·Joanna M. Wardlaw, Fergus Doubal, Rosalind Brown, Ellen V. Backhouse, Lisa J Woodhouse, Philip M. Bath, Terence J. Quinn, Thompson Robinson, Hugh S. Markus, Richard J. McManus, John T. O’Brien, David J. Werring, Nikola Sprigg, Adrian Parry‐Jones, Rhian M. Touyz, Steven E. Williams, Yee‐Haur Mah, Hedley Emsley, (unknown)	2020	14
19	Global phase 2b efficacy and safety trial of florbetaben for beta-amyloid brain positron emission tomography in Alzheimer's disease UCL Discovery (University College London) ·Osama Sabri, (unknown), 冯婷 FENG Ting, Amane Tateno, Alexander Drzezga, Timo Grimmer, Michio Senda, Yasuhiko Yamamoto, Florian Hiemeyer, Ian G. McKeith, John T. O’Brien, Zuzana Walker, Cornelia Reininger, John Seibyl, Henryk Barthel	2011	1
20	How well do we manage families with genetic problems? BMJ ·John T. O’Brien, Raymond Levy, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	1992	1

About John T. O’Brien

John T. O’Brien is a scholar working on Psychiatry and Mental health, Neurology, Biological Psychiatry, Neurology and Physiology, having authored 796 papers that have together received 46.0k indexed citations. Recurring topics across this work include Dementia and Cognitive Impairment Research (338 papers), Alzheimer's disease research and treatments (212 papers), Parkinson's Disease Mechanisms and Treatments (135 papers), Functional Brain Connectivity Studies (122 papers), Advanced Neuroimaging Techniques and Applications (109 papers), Neurological Disease Mechanisms and Treatments (85 papers), Neurological disorders and treatments (42 papers) and Neuroinflammation and Neurodegeneration Mechanisms (40 papers). The work is most often cited by research in Psychiatry and Mental health (18.5k citations), Neurology (8.9k citations), Neurology (12.1k citations), Biological Psychiatry (1.7k citations) and Physiology (12.9k citations). John T. O’Brien has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Ian G. McKeith, Alan Thomas, Clive Ballard, Michael Firbank, David J. Burn, Philip Scheltens, Sean J. Colloby, John‐Paul Taylor, Emma J. Burton and Robert Barber. Their work appears in journals such as International Journal of Geriatric Psychiatry, Neurology, International Psychogeriatrics, Journal of Neurology Neurosurgery & Psychiatry and Alzheimer s & Dementia.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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