Ossama El‐Kabbani

4.4k citations

138 papers · 3.8k indexed · h-index 35

Cell Biology top 0.5%
- Aldose Reductase and Taurine 103
Biochemistry top 1%
Pediatrics, Perinatology and Child Health top 1%
- Prenatal Substance Exposure Effects 41
Molecular Biology top 5%
- Heme Oxygenase-1 and Carbon Monoxide 35
Pharmacology top 2%
- Cannabis and Cannabinoid Research 12
Physiology
- Biochemical effects in animals 26
Endocrinology, Diabetes and Metabolism
- Diet, Metabolism, and Disease 17
- Hormonal Regulation and Hypertension 14
Materials Chemistry
- Enzyme Structure and Function 11

Co-authors: Akira Hara Satoshi Endo Toshiyuki Matsunaga Connie Darmanin M. Schiffer James R. Norris C.-H. Chang Midori Soda
Cited by: Cell Biology Biochemistry Pediatrics, Perinatology and Child Health
Journals: Proceedings of the National Academy of Sciences (1 paper)Journal of Biological Chemistry (1 paper)Journal of Molecular Biology (3 papers)
Partner nations: Japan Australia United States

In The Last Decade

Ossama El‐Kabbani

138 papers receiving 3.7k citations

Peers

Countries citing papers authored by Ossama El‐Kabbani

Since Specialization

Citations

This map shows the geographic impact of Ossama El‐Kabbani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ossama El‐Kabbani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ossama El‐Kabbani more than expected).

Fields of papers citing papers by Ossama El‐Kabbani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ossama El‐Kabbani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ossama El‐Kabbani. The network helps show where Ossama El‐Kabbani may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ossama El‐Kabbani, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ossama El‐Kabbani Line = papers co-authored together Ossama El‐Kabbani links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structure–activity relationship of flavonoids as potent inhibitors of carbonyl reductase 1 (CBR1) Fitoterapia ·Yuki Arai,Satoshi Endo,Namiki Miyagi,Naohito Abe,Takeshi Miura,Toru Nishinaka,Tomoyuki Terada,Masayoshi Oyama,Hiroaki Goda,Ossama El‐Kabbani,Akira Hara,Toshiyuki Matsunaga,Akira Ikari	2014	30
2	Synthesis of non-prenyl analogues of baccharin as selective and potent inhibitors for aldo-keto reductase 1C3 Bioorganic & Medicinal Chemistry ·Satoshi Endo,Dawei Hu,Toshiyuki Matsunaga,Yoko Otsuji,Ossama El‐Kabbani,Mahmoud Kandeel,Akira Ikari,Akira Hara,Yukio Kitade,Naoki Toyooka	2014	23
3	Induction of aldo-keto reductases (AKR1C1 and AKR1C3) abolishes the efficacy of daunorubicin chemotherapy for leukemic U937 cells Anti-Cancer Drugs ·Toshiyuki Matsunaga,Ayano Yamaguchi,Yoshifumi Morikawa,Chihiro Kezuka,Hiroaki Takazawa,Satoshi Endo,Ossama El‐Kabbani,Kazuo Tajima,Akira Ikari,Akira Hara	2014	34
4	Nitric oxide confers cisplatin resistance in human lung cancer cells through upregulation of aldo-keto reductase 1B10 and proteasome Free Radical Research ·Toshiyuki Matsunaga,Yukiko Yamaji,Tatsuru TOMOKUNI,Hidetoshi Morita,Yuka Morikawa,Ayaka Suzuki,Ayano Yonezawa,Satoshi Endo,Akira Ikari,Kazuhiro Iguchi,Ossama El‐Kabbani,Keisuke Tajima,Akira Hara	2014	35
5	Synthesis and structure–activity relationship of 2-phenyliminochromene derivatives as inhibitors for aldo–keto reductase (AKR) 1B10 Bioorganic & Medicinal Chemistry ·Satoshi Endo,Dawei Hu,Miho Suyama,Toshiyuki Matsunaga,Kenji Sugimoto,Yûji Matsuya,Ossama El‐Kabbani,Kazuo Kuwata,Akira Hara,Yukio Kitade,Naoki Toyooka	2013	25
6	Characterization of rabbit aldose reductase-like protein with 3β-hydroxysteroid dehydrogenase activity Archives of Biochemistry and Biophysics ·Satoshi Endo,Toshiyuki Matsunaga,Sho Kumada,Airi Fujimoto,Satoshi Ohno,Ossama El‐Kabbani,Dawei Hu,Naoki Toyooka,Jun’ichi Mano,Kazuo Tajima,Akira Hara	2012	11
7	Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: Its involvement in redox cycling of 9,10-phenanthrenequinone Free Radical Research ·Toshiyuki Matsunaga,Yuhki Shinoda,Yukari Inoue,Yuki Shimizu,Mariko Haga,Satoshi Endo,Ossama El‐Kabbani,Akira Hara	2011	8
8	Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)α-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme Acta Crystallographica Section D Biological Crystallography ·Urmi Dhagat,Satoshi Endo,Hiroaki Mamiya,Akira Hara,Ossama El‐Kabbani	2010	3
9	Protective effect of rat aldo-keto reductase (AKR1C15) on endothelial cell damage elicited by 4-hydroxy-2-nonenal Chemico-Biological Interactions ·Toshiyuki Matsunaga,Yuhki Shinoda,Yukari Inoue,Satoshi Endo,Ossama El‐Kabbani,Akira Hara	2010	9
10	Structure of the G225P/G226P mutant of mouse 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate Acta Crystallographica Section D Biological Crystallography ·Urmi Dhagat,Satoshi Endo,Hiroaki Mamiya,Akira Hara,Ossama El‐Kabbani	2009	2
11	Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor European Journal of Medicinal Chemistry ·Vincenzo Carbone,Marco Giglio,Roland P.‐T. Chung,Trevor Huyton,Julian J. Adams,Rosanna Maccari,Rosaria Ottanà,Akira Hara,Ossama El‐Kabbani	2009	30
12	Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: Probing the active site of the enzyme with molecular modeling and site-directed mutagenesis Biochemical and Biophysical Research Communications ·Toshiyuki Matsunaga,Satoshi Endo,Midori Soda,Hai-Tao Zhao,Ossama El‐Kabbani,Kazuo Tajima,Akira Hara	2009	54
13	Rat NAD+-dependent 3α-hydroxysteroid dehydrogenase (AKR1C17): A member of the aldo-keto reductase family highly expressed in kidney cytosol Archives of Biochemistry and Biophysics ·Masaharu Sanai,Satoshi Endo,Toshiyuki Matsunaga,Shuhei Ishikura,Kazuo Tajima,Ossama El‐Kabbani,Akira Hara	2007	10
14	Molecular Cloning of a Novel Type of Rat Cytoplasmic 17β-Hydroxysteroid Dehydrogenase Distinct from the Type 5 Isozyme The Journal of Biochemistry ·Shuhei Ishikura,Kengo Matsumoto,Masaharu Sanai,Kenji Horie,Toshiyuki Matsunaga,Kazuo Tajima,Ossama El‐Kabbani,Akira Hara	2006	18
15	Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase Acta Crystallographica Section D Biological Crystallography ·Connie Darmanin,Takeshi Iwata,Deborah Carper,Lindsay G. Sparrow,Roland P.‐T. Chung,Ossama El‐Kabbani	2003	2
16	Crystallization and preliminary crystallographic analysis of human L-xylulose reductase Acta Crystallographica Section D Biological Crystallography ·Ossama El‐Kabbani,Roland P.‐T. Chung,Syuhei Ishikura,Noriyuki Usami,Junichi Nakagawa,Akira Hara	2002	6
17	Modelling studies on the binding of substrate and inhibitor to the active site of human sorbitol dehydrogenase Bioorganic & Medicinal Chemistry Letters ·Connie Darmanin,Ossama El‐Kabbani	2000	24
18	Structure of porcine aldehyde reductase holoenzyme Nature Structural Biology ·Ossama El‐Kabbani,K. Judge,Stephan L. Ginell,Dean A. A. Myles,Lawrence J. DeLucas,T. Geoffrey Flynn	1995	55
19	Crystallization and preliminary structure of porcine aldehyde reductase–NADPH binary complex Acta Crystallographica Section D Biological Crystallography ·Ossama El‐Kabbani,K. Judge,Stephan L. Ginell,L.J. DeLucas,T.G. Flynn	1995	1
20	Crystallization and preliminary X-ray investigation of factor D of human complement Journal of Molecular Biology ·Sthanam V.L. Narayana,J. Michael Kilpatrick,Ossama El‐Kabbani,Y.S. Babu,Charles E. Bugg,John E. Volanakis,Lawrence J. DeLucas	1991	4

About Ossama El‐Kabbani

Ossama El‐Kabbani is a scholar working on Cell Biology, Pediatrics, Perinatology and Child Health and Endocrinology, Diabetes and Metabolism, having authored 138 papers that have together received 3.8k indexed citations. Recurring topics across this work include Aldose Reductase and Taurine (103 papers), Prenatal Substance Exposure Effects (41 papers), Heme Oxygenase-1 and Carbon Monoxide (35 papers), Biochemical effects in animals (26 papers), Diet, Metabolism, and Disease (17 papers), Hormonal Regulation and Hypertension (14 papers), Cannabis and Cannabinoid Research (12 papers) and Enzyme Structure and Function (11 papers). The work is most often cited by research in Cell Biology (1.9k citations), Biochemistry (352 citations) and Pediatrics, Perinatology and Child Health (730 citations). Ossama El‐Kabbani has collaborated with scholars based in Japan, Australia and United States. Frequent co-authors include Akira Hara, Satoshi Endo, Toshiyuki Matsunaga, Connie Darmanin, M. Schiffer, James R. Norris, C.-H. Chang, Midori Soda, David M. Tiede and Kazuo Tajima. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Molecular Biology.

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