Michael A. Frohman

23.0k total citations · 4 hit papers
161 papers, 19.1k citations indexed

About

Michael A. Frohman is a scholar working on Molecular Biology, Cell Biology and Genetics. According to data from OpenAlex, Michael A. Frohman has authored 161 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 126 papers in Molecular Biology, 52 papers in Cell Biology and 23 papers in Genetics. Recurrent topics in Michael A. Frohman's work include Protein Kinase Regulation and GTPase Signaling (43 papers), Cellular transport and secretion (42 papers) and Mitochondrial Function and Pathology (21 papers). Michael A. Frohman is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (43 papers), Cellular transport and secretion (42 papers) and Mitochondrial Function and Pathology (21 papers). Michael A. Frohman collaborates with scholars based in United States, Japan and France. Michael A. Frohman's co-authors include Gail R. Martin, Michael Dush, Andrew J. Morris, Guangwei Du, Yelena M. Altshuller, Gary M. Jenkins, Yasunori Kanaho, JoAnne Engebrecht, Elizabeth Scotto–Lavino and Scott M. Hammond and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Michael A. Frohman

160 papers receiving 18.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 4.3k citations Michael A. Frohman et al. profile →
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

1995 903 citations Jayhong A. Chong, José Tapia-Ramı́rez et al. Cell profile →
Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 687 citations Takeaki Yokozeki, Masakazu Yamazaki et al. Cell profile →
Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family

1995 586 citations Yelena M. Altshuller, Michael A. Frohman et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael A. Frohman United States	70	13.5k	4.6k	2.0k	2.0k	1.8k	161	19.1k
Christopher G. Proud United Kingdom	85	17.6k 1.3×	3.7k 0.8×	1.5k 0.7×	2.4k 1.2×	1.8k 1.0×	346	22.9k
Terje Johansen Norway	76	16.1k 1.2×	6.8k 1.5×	1.1k 0.6×	2.8k 1.4×	2.6k 1.5×	169	30.2k
Akira Kikuchi Japan	88	20.4k 1.5×	6.2k 1.3×	2.3k 1.2×	1.3k 0.7×	1.8k 1.0×	463	26.8k
Katsuya Okawa Japan	52	10.3k 0.8×	3.9k 0.8×	1.8k 0.9×	1.1k 0.6×	1.9k 1.1×	118	15.9k
Ian G. Macara United States	83	17.5k 1.3×	7.2k 1.6×	1.5k 0.8×	1.4k 0.7×	1.4k 0.8×	208	23.2k
George Thomas Switzerland	83	18.4k 1.4×	2.9k 0.6×	1.4k 0.7×	3.3k 1.7×	1.9k 1.1×	162	24.4k
En Li United States	57	17.0k 1.3×	2.5k 0.5×	4.7k 2.4×	1.7k 0.9×	1.6k 0.9×	119	22.4k
Hiroshi Nojima Japan	62	10.6k 0.8×	3.5k 0.8×	1.4k 0.7×	1.2k 0.6×	981 0.5×	300	15.8k
Yukiko Gotoh Japan	75	19.2k 1.4×	3.9k 0.8×	2.7k 1.3×	1.8k 0.9×	2.5k 1.4×	153	25.8k
C. Peter Downes United Kingdom	77	19.3k 1.4×	5.5k 1.2×	1.3k 0.6×	2.9k 1.5×	2.5k 1.4×	196	26.5k

Countries citing papers authored by Michael A. Frohman

Since Specialization

Citations

This map shows the geographic impact of Michael A. Frohman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael A. Frohman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael A. Frohman more than expected).

Fields of papers citing papers by Michael A. Frohman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael A. Frohman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael A. Frohman. The network helps show where Michael A. Frohman may publish in the future.

Co-authorship network of co-authors of Michael A. Frohman

This figure shows the co-authorship network connecting the top 25 collaborators of Michael A. Frohman. A scholar is included among the top collaborators of Michael A. Frohman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael A. Frohman. Michael A. Frohman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Krga, Irèna, Fernando Villarreal, Joseph F. LaComb, et al.. (2024). Inhibition of phospholipase D1 reduces pancreatic carcinogenesis in mice partly through a FAK-dependent mechanism. Carcinogenesis. 46(1).

Roth, Eric D. & Michael A. Frohman. (2017). Proliferative and metastatic roles for Phospholipase D in mouse models of cancer. Advances in Biological Regulation. 67. 134–140. 21 indexed citations

Uzor, Philip F., et al.. (2016). Measuring Phospholipase D Enzymatic Activity Through Biochemical and Imaging Methods. Methods in enzymology on CD-ROM/Methods in enzymology. 583. 309–325. 7 indexed citations

Mallipattu, Sandeep K., Vivette D. D’Agati, Goutham Narla, et al.. (2015). Krüppel-like factor 6 regulates mitochondrial function in the kidney. Journal of Clinical Investigation. 125(3). 1347–1361. 65 indexed citations

Baba, Takashi, Nagisa Arimitsu, Kazuki Nakao, et al.. (2014). Phosphatidic Acid (PA)-preferring Phospholipase A1 Regulates Mitochondrial Dynamics. Journal of Biological Chemistry. 289(16). 11497–11511. 104 indexed citations

Choudhary, Vivek, Lawrence O. Olala, Haixia Qin, et al.. (2014). Aquaporin-3 Re-Expression Induces Differentiation in a Phospholipase D2-Dependent Manner in Aquaporin-3-Knockout Mouse Keratinocytes. Journal of Investigative Dermatology. 135(2). 499–507. 26 indexed citations

Frohman, Michael A.. (2014). Role of mitochondrial lipids in guiding fission and fusion. Journal of Molecular Medicine. 93(3). 263–269. 95 indexed citations

Huang, Huiyan & Michael A. Frohman. (2012). Visualizing Mitochondrial Lipids and Fusion Events in Mammalian Cells. Methods in cell biology. 108. 131–145. 8 indexed citations

Tsukahara, Tamotsu, Ryoko Tsukahara, Yuko Fujiwara, et al.. (2010). Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPARγ by Cyclic Phosphatidic Acid. Molecular Cell. 39(3). 421–432. 101 indexed citations

10.

Nishikimi, Akihiko, Hideo Fukuhara, Wenjuan Su, et al.. (2009). Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis. Science. 324(5925). 384–387. 223 indexed citations

11.

Scotto–Lavino, Elizabeth, Miguel Garcı́a-Dı́az, Guangwei Du, & Michael A. Frohman. (2009). Basis for the Isoform-specific Interaction of Myosin Phosphatase Subunits Protein Phosphatase 1c β and Myosin Phosphatase Targeting Subunit 1. Journal of Biological Chemistry. 285(9). 6419–6424. 32 indexed citations

12.

Pannequin, Julie, Nathalie Delaunay, Charbel Darido, et al.. (2007). Phosphatidylethanol Accumulation Promotes Intestinal Hyperplasia by Inducing ZONAB-Mediated Cell Density Increase in Response to Chronic Ethanol Exposure. Molecular Cancer Research. 5(11). 1147–1157. 34 indexed citations

13.

Huang, Ping, et al.. (2006). Synergism between phospholipase D2 and sorbitol accumulation in diabetic cataract formation through modulation of Na,K-ATPase activity and osmotic stress. Experimental Eye Research. 83(4). 939–948. 10 indexed citations

14.

Frohman, Michael A.. (2006). 3′-End cDNA Amplification Using Classic RACE. Cold Spring Harbor Protocols. 2006(1). pdb.prot4130–pdb.prot4130. 3 indexed citations

15.

Watanabe, Hiroshi, Takeaki Yokozeki, Masakazu Yamazaki, et al.. (2004). Essential Role for Phospholipase D2 Activation Downstream of ERK MAP Kinase in Nerve Growth Factor-stimulated Neurite Outgrowth from PC12 Cells. Journal of Biological Chemistry. 279(36). 37870–37877. 41 indexed citations

16.

Choi, Wahn Soo, Young Mi Kim, Christian A. Combs, Michael A. Frohman, & Michael A. Beaven. (2002). Phospholipases D1 and D2 Regulate Different Phases of Exocytosis in Mast Cells. The Journal of Immunology. 168(11). 5682–5689. 110 indexed citations

17.

Altshuller, Yelena M., Neal G. Copeland, Debra J. Gilbert, et al.. (1997). Cloning and expression analysis of murine phospholipase D1. Biochemical Journal. 326(3). 745–753. 107 indexed citations

18.

Altshuller, Yelena M., Neal G. Copeland, Debra J. Gilbert, Nancy A. Jenkins, & Michael A. Frohman. (1996). Gcm1, a mammalian homolog of Drosophila Glial Cells Missing. FEBS Letters. 393(2-3). 201–204. 58 indexed citations

19.

Chong, Jayhong A., José Tapia-Ramı́rez, Juan José Toledo‐Aral, et al.. (1995). REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell. 80(6). 949–957. 903 indexed citations breakdown →

20.

Frohman, Michael A.. (1994). On beyond classic RACE (rapid amplification of cDNA ends).. Genome Research. 4(1). S40–S58. 161 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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