Michael A. Frohman

23.0k citations

161 papers · 19.1k indexed · 4 hit papers · h-index 70

Molecular Biology top 0.2%
Cell Biology top 0.05%
Genetics top 0.5%
Physiology top 1%
Immunology top 1%

Co-authors: Gail R. Martin Michael Dush Andrew J. Morris Guangwei Du Yelena M. Altshuller Gary M. Jenkins JoAnne Engebrecht Yasunori Kanaho
Topics: Protein Kinase Regulation and GTPase Signaling (43 papers)Cellular transport and secretion (42 papers)Mitochondrial Function and Pathology (21 papers)
Cited by: Cell Biology Molecular Biology Biochemistry
Journals: Science Cell Proceedings of the National Academy of Sciences
Partner nations: United States Japan France

In The Last Decade

Michael A. Frohman

160 papers receiving 18.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 4.3k citations Michael A. Frohman et al. profile →
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

1995 903 citations Jayhong A. Chong, José Tapia-Ramı́rez et al. Cell profile →
Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 687 citations Michael A. Frohman, Yasunori Kanaho et al. Cell profile →
Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family

1995 586 citations Yelena M. Altshuller, Michael A. Frohman et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Michael A. Frohman

Since Specialization

Citations

This map shows the geographic impact of Michael A. Frohman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael A. Frohman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael A. Frohman more than expected).

Fields of papers citing papers by Michael A. Frohman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael A. Frohman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael A. Frohman. The network helps show where Michael A. Frohman may publish in the future.

Co-authorship network of co-authors of Michael A. Frohman

This figure shows the co-authorship network connecting the top 25 collaborators of Michael A. Frohman. A scholar is included among the top collaborators of Michael A. Frohman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael A. Frohman. Michael A. Frohman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Inhibition of phospholipase D1 reduces pancreatic carcinogenesis in mice partly through a FAK-dependent mechanism 2024 ·Carcinogenesis ·(unknown),Irèna Krga,Fernando Villarreal,Joseph F. LaComb,Michael A. Frohman,Karen Matsukuma,Gerardo G. Mackenzie	0
2	Prospects for PLD Inhibition in Cancer and Thrombotic Disease 2019 ·Handbook of experimental pharmacology ·(unknown),Michael A. Frohman	2
3	Proliferative and metastatic roles for Phospholipase D in mouse models of cancer 2017 ·Advances in Biological Regulation ·Eric D. Roth,Michael A. Frohman	21
4	Measuring Phospholipase D Enzymatic Activity Through Biochemical and Imaging Methods 2016 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Philip F. Uzor,(unknown),Markus A. Seeliger,Michael A. Frohman	7
5	Krüppel-like factor 6 regulates mitochondrial function in the kidney 2015 ·Journal of Clinical Investigation ·Sandeep K. Mallipattu,(unknown),Vivette D. D’Agati,Goutham Narla,Ruijie Liu,Michael A. Frohman,Kathleen G. Dickman,Edward Y. Chen,Avi Ma’ayan,Agnieszka B. Bialkowska,Amr M. Ghaleb,Mandayam O. Nandan,Mukesh K. Jain,Ilse S. Daehn,Peter Y. Chuang,Vincent W. Yang,John Cijiang He	65
6	Aquaporin-3 Re-Expression Induces Differentiation in a Phospholipase D2-Dependent Manner in Aquaporin-3-Knockout Mouse Keratinocytes 2014 ·Journal of Investigative Dermatology ·Vivek Choudhary,Lawrence O. Olala,Haixia Qin,Inas Helwa,(unknown),(unknown),Michael A. Frohman,Ismail Kaddour‐Djebbar,Wendy B. Bollag	26
7	Phosphatidic Acid (PA)-preferring Phospholipase A1 Regulates Mitochondrial Dynamics 2014 ·Journal of Biological Chemistry ·Takashi Baba,(unknown),Nagisa Arimitsu,(unknown),(unknown),(unknown),Kazuki Nakao,Hiroki Nakanishi,Makoto Kinoshita,Michael A. Frohman,Akitsugu Yamamoto,Katsuko Tani	104
8	Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization, Macrophage Phagocytosis, and Cytokine-Stimulated Neutrophil Recruitment 2013 ·PLoS ONE ·(unknown),Qin Chen,Kathleen E. DelGiorno,Wenjuan Su,Jason C. Hall,Tsunaki Hongu,Huasong Tian,Yasunori Kanaho,Gilbert Di Paolo,Howard C. Crawford,Michael A. Frohman	56
9	Visualizing Mitochondrial Lipids and Fusion Events in Mammalian Cells 2012 ·Methods in cell biology ·Huiyan Huang,Michael A. Frohman	8
10	Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPARγ by Cyclic Phosphatidic Acid 2010 ·Molecular Cell ·Tamotsu Tsukahara,Ryoko Tsukahara,Yuko Fujiwara,Junming Yue,Yunhui Cheng,Huazhang Guo,(unknown),Chunxiang Zhang,Louisa Balázs,Fabio Re,Guangwei Du,Michael A. Frohman,Daniel L. Baker,Abby L. Parrill,Ayako Uchiyama,Tetsuyuki Kobayashi,Kimiko Murakami‐Murofushi,Gábor Tigyi	101
11	Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis 2009 ·Science ·Akihiko Nishikimi,Hideo Fukuhara,Wenjuan Su,Tsunaki Hongu,Shunsuke Takasuga,Hisashi Mihara,Qinhong Cao,Fumiyuki Sanematsu,Motomu Kanai,Hiroshi Hasegawa,Yoshihiko Tanaka,Masakatsu Shibasaki,Yasunori Kanaho,Takehiko Sasaki,Michael A. Frohman,Yoshinori Fukui	223
12	Basis for the Isoform-specific Interaction of Myosin Phosphatase Subunits Protein Phosphatase 1c β and Myosin Phosphatase Targeting Subunit 1 2009 ·Journal of Biological Chemistry ·Elizabeth Scotto–Lavino,Miguel Garcı́a-Dı́az,Guangwei Du,Michael A. Frohman	32
13	Phosphatidylethanol Accumulation Promotes Intestinal Hyperplasia by Inducing ZONAB-Mediated Cell Density Increase in Response to Chronic Ethanol Exposure 2007 ·Molecular Cancer Research ·Julie Pannequin,Nathalie Delaunay,Charbel Darido,Tangui Maurice,(unknown),Michael A. Frohman,María S. Balda,Karl Matter,Dominique Joubert,(unknown),Jean-Pierre Balì,Frédéric Hollande	34
14	Synergism between phospholipase D2 and sorbitol accumulation in diabetic cataract formation through modulation of Na,K-ATPase activity and osmotic stress 2006 ·Experimental Eye Research ·Ping Huang,Zhirong Jiang,(unknown),(unknown),Michael A. Frohman,Sookja Kim Chung,Stephen S. Chung,(unknown),(unknown)	10
15	Cloning cDNA Ends Using RACE 2003 ·Humana Press eBooks ·Yue Zhang,Michael A. Frohman	4
16	Phospholipases D1 and D2 Regulate Different Phases of Exocytosis in Mast Cells 2002 ·The Journal of Immunology ·Wahn Soo Choi,Young Mi Kim,Christian A. Combs,Michael A. Frohman,Michael A. Beaven	110
17	Gcm1, a mammalian homolog of Drosophila Glial Cells Missing 1996 ·FEBS Letters ·Yelena M. Altshuller,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Michael A. Frohman	58
18	REST: A mammalian silencer protein that restricts sodium channel gene expression to neuronsbreakdown → 1995 ·Cell ·Jayhong A. Chong,José Tapia-Ramı́rez,(unknown),Juan José Toledo‐Aral,Yingcong Zheng,Michael Boutros,Yelena M. Altshuller,Michael A. Frohman,Susan D. Kraner,Gail Mandel	903
19	On beyond classic RACE (rapid amplification of cDNA ends). 1994 ·Genome Research ·Michael A. Frohman	161
20	[23] Radioimmunoassay of human adenosine deaminase 1981 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Peter E. Daddona,Michael A. Frohman,William N. Kelley	1

About Michael A. Frohman

Michael A. Frohman is a scholar working on Cell Biology, Physiology and Molecular Biology, having authored 161 papers that have together received 19.1k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (43 papers), Cellular transport and secretion (42 papers) and Mitochondrial Function and Pathology (21 papers). The work is most often cited by research in Cell Biology (4.6k citations), Molecular Biology (13.5k citations) and Biochemistry (1.1k citations). Michael A. Frohman has collaborated with scholars based in United States, Japan and France. Frequent co-authors include Gail R. Martin, Michael Dush, Andrew J. Morris, Guangwei Du, Yelena M. Altshuller, Gary M. Jenkins, JoAnne Engebrecht, Yasunori Kanaho, Elizabeth Scotto–Lavino and Scott M. Hammond. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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