Melvin I. Simon

44.6k citations

320 papers · 34.8k indexed · 6 hit papers · h-index 110

Impact in

Cellular and Molecular Neuroscience top 0.05%
- Photoreceptor and optogenetics research
- Neuroscience and Neuropharmacology Research
Molecular Biology top 0.05%
- Receptor Mechanisms and Signaling
- Protein Kinase Regulation and GTPase Signaling
- RNA and protein synthesis mechanisms
- Retinal Development and Disorders

Papers in

Molecular Biology 269
- RNA and protein synthesis mechanisms 56
- Receptor Mechanisms and Signaling 50
- Protein Kinase Regulation and GTPase Signaling 49
- Retinal Development and Disorders 32
- Protein Structure and Dynamics 23
Genetics 103
- Bacterial Genetics and Biotechnology 80

Co-authors: M. Silverman M Strathmann N. Gautam Stefan Offermanns Judith Hess Lisa A. Alex Valeria Mancino Robert B. Bourret
Journals: Proceedings of the National Academy of Sciences (59 papers)Journal of Biological Chemistry (39 papers)Journal of Bacteriology (38 papers)Science (18 papers)Nature (16 papers)
Partner nations: United States Germany Japan

In The Last Decade

Melvin I. Simon

319 papers receiving 33.4k citations

Hit Papers

6 papers align trajectories log scale

A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons 2001 · 546 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 Cell
2000 Proceedings of the National Academy of Sciences
1992 Proceedings of the National Academy of Sciences
1991 Science
1984 Science
1974 Nature

Peers

Countries citing papers authored by Melvin I. Simon

Since Specialization

Citations

This map shows the geographic impact of Melvin I. Simon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Melvin I. Simon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Melvin I. Simon more than expected).

Fields of papers citing papers by Melvin I. Simon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Melvin I. Simon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Melvin I. Simon. The network helps show where Melvin I. Simon may publish in the future.

Co-authors

The 25 scholars most cited alongside Melvin I. Simon, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Melvin I. Simon Line = papers co-authored together Melvin I. Simon links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier Proceedings of the National Academy of Sciences ·Ajit S. Divakaruni, Sandra E. Wiley, George W. Rogers, Alexander Y. Andreyev, Susanna Petrosyan, Muhetaibaier Hairoula, Estelle A. Wall, Nagendra Yadava, Alejandro P. Heuck, David A. Ferrick, Robert R. Henry, William Graham McDonald, Jerry R. Colca, Melvin I. Simon, Theodore P. Ciaraldi, Anne N. Murphy	2013	237
2	NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain Proceedings of the National Academy of Sciences ·Donghoon Kim, W. A. Braun, Eun‐Kyeong Jo, В.Б. Виноградов, Melvin I. Simon, Sung Joong Lee	2010	205
3	Molecular architecture of Gα _o and the structural basis for RGS16-mediated deactivation Proceedings of the National Academy of Sciences ·Kevin C. Slep, Michele A. Kercher, Thomas Wieland, Ching-Kang Chen, Melvin I. Simon, Paul B. Sigler	2008	51
4	A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression Proceedings of the National Academy of Sciences ·Kum-Joo Shin, Estelle A. Wall, 明石井, Leah A. Santat, Jamie Liu, Jong‐Ik Hwang, Robert A. Rebres, Tamara I. A. Roach, William E. Seaman, Melvin I. Simon, Iain D. C. Fraser	2006	264
5	Dual Ligand Stimulation of RAW 264.7 Cells Uncovers Feedback Mechanisms That Regulate TLR-Mediated Gene Expression The Journal of Immunology ·Xiaocui Zhu, Mi Sook Chang, Robert C. Hsueh, Y. Moreau, Kelly D. Smith, Melvin I. Simon, Sangdun Choi	2006	15
6	In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved Proceedings of the National Academy of Sciences ·Sang‐Youn Park, Daian Tatiana Flórez Q, Melvin I. Simon, A.M. Bilwes, Brian R. Crane	2004	51
7	Effects of Blue- and Green Light in Arrestin / Rhodopsinkinase Double Knock Out (Arr-/- / RK -/-) Mice Investigative Ophthalmology & Visual Science ·V.P. Sereda, Christian Grimm, Melvin I. Simon, Anna G. Wenzel	2003	1
8	Novel Form of Adaptation in Mouse Retinal Rods Speeds Recovery of Phototransduction The Journal of General Physiology ·Claudia M. Krispel, Ching-Kang Chen, Melvin I. Simon, Marie E. Burns	2003	43
9	Methacholine-induced airway hyperresponsiveness is dependent on Gα_qsignaling American Journal of Physiology-Lung Cellular and Molecular Physiology ·Michael T. Borchers, Travis L. Biechele, J. Paul Justice, Prashant More, Stephania A. Cormier, Valeria Mancino, E A Essock, Melvin I. Simon, K. Fathi, Fabiano Coluccia	2003	18
10	Interaction of Gα ₁₂ with Gα ₁₃ and Gα _q signaling pathways Proceedings of the National Academy of Sciences ·Jennifer Gu, Stefan Müller, Valeria Mancino, Stefan Offermanns, Melvin I. Simon	2002	103
11	Gq Signaling Is Required for Allergen-Induced Pulmonary Eosinophilia The Journal of Immunology ·Michael T. Borchers, A. R. Gower, Prashant More, Valeria Mancino, Michael P. McGarry, Jeffrey R. Crosby, Melvin I. Simon, Nancy A. Lee, James J. Lee	2002	18
12	Interaction of the Xanthine Nucleotide Binding Goα Mutant with G Protein-coupled Receptors Journal of Biological Chemistry ·Bo Yu, Melvin I. Simon	1998	20
13	PhLPs and PhLOPs in the phosducin family of gβy binding proteins Investigative Ophthalmology & Visual Science ·Cheryl M. Craft, Jun Xu, Vladlen Z. Slepak, B. M. Brown, 久夫遠藤, Melvin I. Simon, Richard N. Lolley	1997	1
14	Phosphorylation and regulation of G-protein beta-gamma-activated phospholipase C-beta-2 by cAMP-dependent protein kinase The FASEB Journal ·Genya Okada, Melvin I. Simon	1996	1
15	Phospholipase beta-4-knockout mouse exhibits retinal phenotype Investigative Ophthalmology & Visual Science ·Huiping Jiang, Arkady Lyubarsky, Noga Vardi, Randal Moseley, J. Chen, Jun‐Wei Xu, Melvin I. Simon, Di Wu	1996	1
16	Localized perturbations in CheY structure monitored by NMR identify a CheA binding interface Nature Structural Biology ·Ronald V. Swanson, David F. Lowry, Philip Matsumura, Megan M. McEvoy, Melvin I. Simon, Frederick W. Dahlquist	1995	34
17	The transforming activity of activated Gα12 FEBS Letters ·Huiping Jiang, Dianqing Wu, Melvin I. Simon	1993	92
18	Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice Neuron ·Janis Lem, Meredithe Applebury, Jeffrey Falk, John G. Flannery, Melvin I. Simon	1991	150
19	Recombinational Regulation of Gene Expression in Bacteria Cold Spring Harbor Monograph Archive ·Melvin I. Simon, M. Silverman	1983	14
20	The Mechanism of Phase Variation Cold Spring Harbor Monograph Archive ·Janine Zieg, M. Silverman, Marcia Hilmen, Melvin I. Simon	1980	10

About Melvin I. Simon

Melvin I. Simon is a scholar working on Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Immunology and Allergy and Aging, having authored 320 papers that have together received 34.8k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (80 papers), RNA and protein synthesis mechanisms (56 papers), Receptor Mechanisms and Signaling (50 papers), Protein Kinase Regulation and GTPase Signaling (49 papers), Bacteriophages and microbial interactions (37 papers), Retinal Development and Disorders (32 papers), Photoreceptor and optogenetics research (26 papers) and Protein Structure and Dynamics (23 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (7.4k citations), Molecular Biology (25.6k citations), Aging (614 citations), Genetics (7.7k citations) and Cell Biology (3.5k citations). Melvin I. Simon has collaborated with scholars based in United States, Germany and Japan. Frequent co-authors include M. Silverman, M Strathmann, N. Gautam, Stefan Offermanns, Judith Hess, Lisa A. Alex, Valeria Mancino, Robert B. Bourret, Arieh A. Katz and Katherine A. Borkovich. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Journal of Bacteriology, Science and Nature.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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