Marlene M. Rayner

1.8k citations

19 papers · 1.3k indexed · 1 hit paper · h-index 14

Impact in

Virology top 1%
- HIV Research and Treatment
Infectious Diseases top 2%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in

Virology 15
- HIV Research and Treatment 15
Infectious Diseases 16
- HIV/AIDS drug development and treatment 16
- HIV/AIDS Research and Interventions 4

Co-authors: Susan Erickson‐Viitanen Lee T. Bacheler Chong‐Hwan Chang David A. Jackson Patrick Y. S. Lam Michaël Otto Prabhakar K. Jadhav Charles J. Eyermann
Journals: Bioorganic & Medicinal Chemistry Letters (4 papers)Journal of Medicinal Chemistry (3 papers)Antimicrobial Agents and Chemotherapy (3 papers)AIDS Research and Human Retroviruses (2 papers)Antiviral chemistry & chemotherapy (1 paper)
Partner nations: United States

In The Last Decade

Marlene M. Rayner

19 papers receiving 1.3k citations

Hit Papers

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Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors 1994 · 680 citations

Peers

Countries citing papers authored by Marlene M. Rayner

Since Specialization

Citations

This map shows the geographic impact of Marlene M. Rayner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marlene M. Rayner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marlene M. Rayner more than expected).

Fields of papers citing papers by Marlene M. Rayner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marlene M. Rayner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marlene M. Rayner. The network helps show where Marlene M. Rayner may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Marlene M. Rayner, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Marlene M. Rayner Line = papers co-authored together Marlene M. Rayner links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	DPC 817: a Cytidine Nucleoside Analog with Activity against Zidovudine- and Lamivudine-Resistant Viral Variants Antimicrobial Agents and Chemotherapy ·Raymond F. Schinazi, John W. Mellors, Holly Bazmi, Sharon Diamond, Sena Garber, Karen Gallagher, Romas Geleziunas, Tae-Hwan Byun, Michael E. Pierce, Marlene M. Rayner, Jingtao Wu, Hangchun Zhang, Jennifer Hammond, Lee T. Bacheler, Douglas J. Manion, Michaël Otto, Lieven Stuyver, George L. Trainor, Dennis C. Liotta, Susan Erickson‐Viitanen	2002	39
2	Efavirenz Is a Potent Nonnucleoside Reverse Transcriptase Inhibitor of HIV Type 1 Replication in Microglia in Vitro AIDS Research and Human Retroviruses ·Andrew Albright, Susan Erickson‐Viitanen, Michael J. O’Connor, Ian Frank, Marlene M. Rayner, Francisco González‐Scarano	2000	11
3	The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: Modifications of the P1/P1′ residues Bioorganic & Medicinal Chemistry Letters ·Mona Patel, Lee T. Bacheler, Marlene M. Rayner, Beverly C. Cordova, Ronald M. Klabe, Susan Erickson‐Viitanen, Steven P. Seitz	1998	16
4	Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies Journal of Medicinal Chemistry ·Prabhakar K. Jadhav, Francis J. Woerner, Patrick Y. S. Lam, C. Nicholas Hodge, Charles J. Eyermann, Hon‐Wah Man, Patti Crimmins, Lee T. Bacheler, Marlene M. Rayner, James L. Meek, Susan Erickson‐Viitanen, David A. Jackson, Joseph C. Calabrese, M. Schadt, Chong‐Hwan Chang	1998	42
5	Population Dynamics Studies of Wild-Type and Drug-Resistant Mutant HIV in Mixed Infections Virology ·Marlene M. Rayner, Beverly C. Cordova, David A. Jackson	1997	20
6	Design, Synthesis, and Evaluation of Tetrahydropyrimidinones as an Example of a General Approach to Nonpeptide HIV Protease Inhibitors Journal of Medicinal Chemistry ·George V. De Lucca, Jing Liang, Paul E. Aldrich, J. C. CALABRESE, Beverly C. Cordova, Ronald M. Klabe, Marlene M. Rayner, Chong‐Hwan Chang	1997	40
7	Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Bioorganic & Medicinal Chemistry Letters ·Joanne M. Smallheer, Robert J. McHugh, Chong‐Hwan Chang, Robert F. Kaltenbach, Lluvia Gonzalez-Castro, Ronald M. Klabe, Lee T. Bacheler, Marlene M. Rayner, Susan Erickson‐Viitanen, Steven P. Seitz	1997	1
8	Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease Journal of Virology ·Á. Kiss, Steve C. Pettit, R.J. Tritch, Kallebo, Linnea, Ms., Marlene M. Rayner, Ronald Swanstrom, Susan Erickson‐Viitanen	1997	45
9	Selection conditions affect the evolution of specific mutations in the reverse transcriptase gene associated with resistance to DMP 266 AIDS ·Dean L. Winslow, Sena Garber, Carol Reid, Helen Scarnati, David Baker, Marlene M. Rayner, Elizabeth D. Anton	1996	44
10	Synthesis of (+)-biotin derivatives as HIV-1 protease inhibitors Bioorganic & Medicinal Chemistry Letters ·Qi Han, Jennifer Lafontaine, Lee T. Bacheler, Marlene M. Rayner, Ronald M. Klabe, Susan Erickson‐Viitanen, Patrick Y. S. Lam	1996	3
11	Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups Bioorganic & Medicinal Chemistry Letters ·James D. Rodgers, Barry L. Johnson, Haisheng Wang, Roger A. Greenberg, Susan Erickson‐Viitanen, Ronald M. Klabe, Beverly C. Cordova, Marlene M. Rayner, Gilbert N. Lam, Chong‐Hwan Chang	1996	96
12	Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450 Chemistry & Biology ·Pratik Kumar Kundu, Paul E. Aldrich, Lee T. Bacheler, Chong‐Hwan Chang, Charles J. Eyermann, Sena Garber, Mary F. Grubb, David A. Jackson, Igor Valerievich Shishkin, Bruce D. Korant, Patrick Y. S. Lam, Michael B. Maurin, James L. Meek, Michaël Otto, Marlene M. Rayner, Carol Reid, Thomas R. Sharpe, Linyee Shum, Dean L. Winslow, Susan Erickson‐Viitanen	1996	119
13	Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors Journal of Medicinal Chemistry ·David A. Nugiel, Hyunmoo Lee, Lluvia Gonzalez-Castro, Mona Patel, Robert F. Kaltenbach, Dayton T. Meyer, Prabhakar K. Jadhav, George V. De Lucca, D. A. TROPIN, Ronald M. Klabe, Lee T. Bacheler, Marlene M. Rayner, Steven P. Seitz	1996	94
14	ChemInform Abstract: Preparation and Structure‐Activity Relationship of Novel P1/P1′‐ Substituted Cyclic Urea‐Based Human Immunodeficiency Virus Type‐1 Protease Inhibitors. ChemInform ·David A. Nugiel, Hyunmoo Lee, Lluvia Gonzalez-Castro, M. PATEL, Robert F. Kaltenbach, Dayton T. Meyer, Richard Stalin Bautista Guzmán, George V. De Lucca, D. A. TROPIN, Ronald M. Klabe, Lee T. Bacheler, Marlene M. Rayner, Steven P. Seitz	1996	2
15	DMP 323, a nonpeptide cyclic urea inhibitor of human immunodeficiency virus (HIV) protease, specifically and persistently blocks intracellular processing of HIV gag polyprotein Antimicrobial Agents and Chemotherapy ·Marlene M. Rayner, Beverly C. Cordova, M. J. Gerard, Paul E. Aldrich, Richard Stalin Bautista Guzmán, Xiaoshu Gao, Patrick Y. S. Lam	1994	15
16	Studies on Orally Available Inhibitors of HIV Protease. Peptidyl Aldehydes and Trifluoromethyl Ketones Antiviral chemistry & chemotherapy ·C. Nicholas Hodge, Paul E. Aldrich, Cấnh Toàn Nguyễn, Eun Young Park, Marlene M. Rayner, Y. Nancy Wong, Susan Erickson‐Viitanen	1994	8
17	Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors Science ·Patrick Y. S. Lam, Prabhakar K. Jadhav, Charles J. Eyermann, C. Nicholas Hodge, Yu Ru, Lee T. Bacheler, James L. Meek, Michaël Otto, Marlene M. Rayner, Y. Nancy Wong, Chong‐Hwan Chang, Patricia C Weber, David A. Jackson, Thomas R. Sharpe, Susan Erickson‐Viitanen Hit paper breakdown →	1994	680
18	In vitro anti-human immunodeficiency virus (HIV) activity of XM323, a novel HIV protease inhibitor Antimicrobial Agents and Chemotherapy ·Michaël Otto, Carol Reid, Sena Garber, Patrick Y. S. Lam, Helen Scarnati, Lee T. Bacheler, Marlene M. Rayner, Dean L. Winslow	1993	30
19	HIV-1 Neutralizing Monoclonal Antibodies Induced by a Synthetic Peptide AIDS Research and Human Retroviruses ·Paul J. Durda, Lee T. Bacheler, Paul R. Clapham, Konrad Ludviksson, Barbara A. Leece, Thomas J. Matthews, Áine McKnight, Roger J. Pomerantz, Marlene M. Rayner, Kent J. Weinhold	1990	40

About Marlene M. Rayner

Marlene M. Rayner is a scholar working on Virology, Infectious Diseases, Emergency Medicine, Organic Chemistry and Hepatology, having authored 19 papers that have together received 1.3k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (16 papers), HIV Research and Treatment (15 papers), Biochemical and Molecular Research (5 papers), Click Chemistry and Applications (4 papers), HIV/AIDS Research and Interventions (4 papers), HIV-related health complications and treatments (2 papers), Biotin and Related Studies (2 papers) and T-cell and Retrovirus Studies (1 paper). The work is most often cited by research in Virology (533 citations), Infectious Diseases (597 citations), Organic Chemistry (527 citations), Process Chemistry and Technology (42 citations) and Computational Theory and Mathematics (214 citations). Marlene M. Rayner has collaborated with scholars based in United States. Frequent co-authors include Susan Erickson‐Viitanen, Lee T. Bacheler, Chong‐Hwan Chang, David A. Jackson, Patrick Y. S. Lam, Michaël Otto, Prabhakar K. Jadhav, Charles J. Eyermann, James L. Meek and Thomas R. Sharpe. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Antimicrobial Agents and Chemotherapy, AIDS Research and Human Retroviruses and Antiviral chemistry & chemotherapy.

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