George V. De Lucca

1.0k citations

19 papers · 608 indexed · h-index 13

Virology top 5%
- HIV Research and Treatment 8
Organic Chemistry top 5%
- Click Chemistry and Applications 6
- Carbohydrate Chemistry and Synthesis 4
Infectious Diseases top 10%
- HIV/AIDS drug development and treatment 15
Process Chemistry and Technology
Computational Theory and Mathematics top 10%
Molecular Biology
- Chemical Synthesis and Analysis 6
- Biochemical and Molecular Research 5
Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment 2
Oncology
- Chemokine receptors and signaling 2

Co-authors: Patrick Y. S. Lam Jing Liang William C. Ripka Richard S. Pottorf Jeffrey M. Blaney A. Bach Michaël Otto Susan Erickson‐Viitanen
Cited by: Virology Organic Chemistry Infectious Diseases
Journals: Journal of the American Chemical Society (1 paper)Journal of Medicinal Chemistry (5 papers)The Journal of Organic Chemistry (1 paper)
Partner nations: United States

In The Last Decade

George V. De Lucca

19 papers receiving 589 citations

Peers

Countries citing papers authored by George V. De Lucca

Since Specialization

Citations

This map shows the geographic impact of George V. De Lucca's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George V. De Lucca with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George V. De Lucca more than expected).

Fields of papers citing papers by George V. De Lucca

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George V. De Lucca. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George V. De Lucca. The network helps show where George V. De Lucca may publish in the future.

Co-authorship network

The 25 scholars most cited alongside George V. De Lucca, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with George V. De Lucca Line = papers co-authored together George V. De Lucca links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2) Bioorganic & Medicinal Chemistry Letters ·Michael G. Yang,Zili Xiao,Qing Shi,Robert J. Cherney,Andrew J. Tebben,George V. De Lucca,Joseph B. Santella,Ruowei Mo,Mary Ellen Cvijic,Qihong Zhao,Joel C. Barrish,Percy H. Carter	2011	2
2	De Novo Design and Discovery of Cyclic HIV Protease Inhibitors Capable of Displacing the Active-Site Structural Water Molecule Pharmaceutical biotechnology ·George V. De Lucca,Prabhakar K. Jadhav,Robert E. Waltermire,Bruce J. Aungst,Susan Erickson‐Viitanen,Patrick Y. S. Lam	2002	6
3	Discovery and Structure−Activity Relationship of N-(Ureidoalkyl)-Benzyl-Piperidines As Potent Small Molecule CC Chemokine Receptor-3 (CCR3) Antagonists Journal of Medicinal Chemistry ·George V. De Lucca,Ui T. Kim,Curt Johnson,Brian J. Vargo,Patricia K. Welch,Maryanne Covington,Paul Davies,Kimberly A. Solomon,Robert Newton,George L. Trainor,Carl P. Decicco,Soo S. Ko	2002	32
4	Does a diol cyclic urea inhibitor of HIV-1 protease bind tighter than its corresponding alcohol form? A study by free energy perturbation and continuum electrostatics calculations Journal of Computer-Aided Molecular Design ·Lu Wang,Yong Duan,Pieter F. W. Stouten,George V. De Lucca,Ronald M. Klabe,Peter A. Kollman	2001	10
5	ChemInform Abstract: Stereospecific Synthesis, Structure—Activity Relationship, and Oral Bioavailability of Tetrahydropyrimidin‐2‐one HIV Protease Inhibitors. ChemInform ·George V. De Lucca,Jing Liang,Indawati De Lucca	1999	2
6	De novo design, discovery and development of cyclic urea HIV protease inhibitors Drugs of the Future ·George V. De Lucca,Patrick Y. S. Lam	1998	35
7	Nonsymmetric P2/P2‘ Cyclic Urea HIV Protease Inhibitors. Structure−Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues Journal of Medicinal Chemistry ·George V. De Lucca,Ui T. Kim,Jing Liang,Beverly C. Cordova,Ronald M. Klabe,Sena Garber,Lee T. Bacheler,Gilbert N. Lam,Matthew Wright,Kelly Logue,Susan Erickson‐Viitanen,Soo S. Ko,George L. Trainor	1998	43
8	Stereospecific Synthesis, Structure−Activity Relationship, and Oral Bioavailability of Tetrahydropyrimidin-2-one HIV Protease Inhibitors Journal of Medicinal Chemistry ·George V. De Lucca,Jing Liang,Indawati De Lucca	1998	47
9	Stereospecific, Stereoselective Rearrangement of Hexahydro-1,3-diazepin-2-ones to Tetrahydropyrimidin-2-ones and Imidazolidin-2-ones, a Useful Route for the Synthesis of HIV Protease Inhibitors The Journal of Organic Chemistry ·George V. De Lucca	1998	17
10	Calculated and Experimental Low-Energy Conformations of Cyclic Urea HIV Protease Inhibitors Journal of the American Chemical Society ·C. Nicholas Hodge,Patrick Y. S. Lam,Charles J. Eyermann,Prabhakar K. Jadhav,Y. Ru,Christina H. Fernandez,George V. De Lucca,Chong‐Hwan Chang,Robert F. Kaltenbach,Edward R. Holler,Francis J. Woerner,Wayne F. Daneker,George Emmett,Joseph C. Calabrese,Paul E. Aldrich	1998	42
11	Design, Synthesis, and Evaluation of Tetrahydropyrimidinones as an Example of a General Approach to Nonpeptide HIV Protease Inhibitors Journal of Medicinal Chemistry ·George V. De Lucca,Jing Liang,Paul E. Aldrich,J. C. CALABRESE,Beverly C. Cordova,Ronald M. Klabe,Marlene M. Rayner,Chong‐Hwan Chang	1997	40
12	Synthesis and evaluation of imidazolidinones as nonpeptide HIV-protease inhibitors Bioorganic & Medicinal Chemistry Letters ·George V. De Lucca	1997	7
13	Synthesis and evaluation of delta lactams as nonpeptide HIV-protease inhibitors Bioorganic & Medicinal Chemistry Letters ·George V. De Lucca	1997	17
14	Cyclic HIV protease inhibitors capable of displacing the active site structural water molecule Drug Discovery Today ·George V. De Lucca,Susan Erickson‐Viitanen,Patrick Y. S. Lam	1997	49
15	Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors Journal of Medicinal Chemistry ·David A. Nugiel,Kim Jacobs,Tabitha V. Worley,Mona Patel,Robert F. Kaltenbach,Dayton T. Meyer,Prabhakar K. Jadhav,George V. De Lucca,Thomas E. Smyser,Ronald M. Klabe,Lee T. Bacheler,Marlene M. Rayner,Steven P. Seitz	1996	94
16	ChemInform Abstract: Preparation and Structure‐Activity Relationship of Novel P1/P1′‐ Substituted Cyclic Urea‐Based Human Immunodeficiency Virus Type‐1 Protease Inhibitors. ChemInform ·David A. Nugiel,Kim Jacobs,Tabitha V. Worley,M. PATEL,Robert F. Kaltenbach,Dayton T. Meyer,P. K. JADHAV,George V. De Lucca,Thomas E. Smyser,Ronald M. Klabe,Lee T. Bacheler,Marlene M. Rayner,Steven P. Seitz	1996	2
17	Protein β-turn mimetics II: Design, synthesis, and evaluation in the cyclic peptide gramicidin S Tetrahedron ·William C. Ripka,George V. De Lucca,A. Bach,Richard S. Pottorf,Jeffrey M. Blaney	1993	37
18	Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides. Tetrahedron ·William C. Ripka,George V. De Lucca,A. Bach,Richard S. Pottorf,Jeffrey M. Blaney	1993	81
19	Synthesis and anti-HIV activity of pyrrolo-[1,2-d]-(1,4)-benzodiazepin-6-ones Bioorganic & Medicinal Chemistry Letters ·George V. De Lucca,Michaël Otto	1992	45

About George V. De Lucca

George V. De Lucca is a scholar working on Virology, Infectious Diseases and Organic Chemistry, having authored 19 papers that have together received 608 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (15 papers), HIV Research and Treatment (8 papers), Click Chemistry and Applications (6 papers), Chemical Synthesis and Analysis (6 papers), Biochemical and Molecular Research (5 papers), Carbohydrate Chemistry and Synthesis (4 papers), Pneumocystis jirovecii pneumonia detection and treatment (2 papers) and Chemokine receptors and signaling (2 papers). The work is most often cited by research in Virology (109 citations), Organic Chemistry (375 citations) and Infectious Diseases (169 citations). George V. De Lucca has collaborated with scholars based in United States. Frequent co-authors include Patrick Y. S. Lam, Jing Liang, William C. Ripka, Richard S. Pottorf, Jeffrey M. Blaney, A. Bach, Michaël Otto, Susan Erickson‐Viitanen, Ronald M. Klabe and Marlene M. Rayner. Their work appears in journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

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