Barbara A. Leece

1.6k total citations
17 papers, 1.2k citations indexed

About

Barbara A. Leece is a scholar working on Radiology, Nuclear Medicine and Imaging, Oncology and Molecular Biology. According to data from OpenAlex, Barbara A. Leece has authored 17 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Radiology, Nuclear Medicine and Imaging, 9 papers in Oncology and 6 papers in Molecular Biology. Recurrent topics in Barbara A. Leece's work include Monoclonal and Polyclonal Antibodies Research (10 papers), HER2/EGFR in Cancer Research (9 papers) and Advanced Biosensing Techniques and Applications (2 papers). Barbara A. Leece is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (10 papers), HER2/EGFR in Cancer Research (9 papers) and Advanced Biosensing Techniques and Applications (2 papers). Barbara A. Leece collaborates with scholars based in United States, Japan and Canada. Barbara A. Leece's co-authors include Victor S. Goldmacher, Yelena Kovtun, Hongsheng Xie, Ravi Chari, Walter A. Blättler, Wayne C. Widdison, Charlene A. Audette, Sharon Wilhelm, Robert Y. Zhao and Thomas Chittenden and has published in prestigious journals such as Cancer Research, Journal of Medicinal Chemistry and Bioconjugate Chemistry.

In The Last Decade

Barbara A. Leece

17 papers receiving 1.1k citations

Peers

Barbara A. Leece

ONCOL

RNMI

IMMUN

Shang‐Fan Yu United States

Jay Sarup United States

Shenlan Mao United States

Django Sussman United States

Gary R. Braslawsky United States

Lisa Crocker United States

Kathryn L. Parsons United States

Jamie B. Miyamoto United States

Deborah A. Scollard Canada

Joshua H. Hunter United States

Shang‐Fan Yu United States

Barbara A. Leece

833 ×1.0

ONCOL

864 ×1.1

RNMI

929 ×2.4

101 ×0.6

280 ×2.3

IMMUN

Citations per year, relative to Barbara A. Leece Barbara A. Leece (= 1×) peers Shang‐Fan Yu

Countries citing papers authored by Barbara A. Leece

Since Specialization

Citations

This map shows the geographic impact of Barbara A. Leece's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barbara A. Leece with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barbara A. Leece more than expected).

Fields of papers citing papers by Barbara A. Leece

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barbara A. Leece. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barbara A. Leece. The network helps show where Barbara A. Leece may publish in the future.

Co-authorship network of co-authors of Barbara A. Leece

This figure shows the co-authorship network connecting the top 25 collaborators of Barbara A. Leece. A scholar is included among the top collaborators of Barbara A. Leece based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Barbara A. Leece. Barbara A. Leece is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Widdison, Wayne C., Sharon Wilhelm, Gregory E. Jones, et al.. (2015). Metabolites of Antibody–Maytansinoid Conjugates: Characteristics andin VitroPotencies. Molecular Pharmaceutics. 12(6). 1762–1773. 22 indexed citations

Zhao, Robert Y., Sharon Wilhelm, Charlene A. Audette, et al.. (2011). Synthesis and Evaluation of Hydrophilic Linkers for Antibody–Maytansinoid Conjugates. Journal of Medicinal Chemistry. 54(10). 3606–3623. 150 indexed citations

Sun, Xiuxia, Wayne C. Widdison, Michele Mayo, et al.. (2011). Design of Antibody−Maytansinoid Conjugates Allows for Efficient Detoxification via Liver Metabolism. Bioconjugate Chemistry. 22(4). 728–735. 64 indexed citations

Kellogg, Brenda, Lisa M. Garrett, Yelena Kovtun, et al.. (2011). Disulfide-Linked Antibody−Maytansinoid Conjugates: Optimization of In Vivo Activity by Varying the Steric Hindrance at Carbon Atoms Adjacent to the Disulfide Linkage. Bioconjugate Chemistry. 22(4). 717–727. 152 indexed citations

Zhao, Robert Y., Hans K. Erickson, Barbara A. Leece, et al.. (2011). Synthesis and Biological Evaluation of Antibody Conjugates of Phosphate Prodrugs of Cytotoxic DNA Alkylators for the Targeted Treatment of Cancer. Journal of Medicinal Chemistry. 55(2). 766–782. 47 indexed citations

Kovtun, Yelena, Gregory E. Jones, Charlene A. Audette, et al.. (2010). 235 Negatively-charged sulfonate group in linker improves potency of antibody–maytansinoid conjugates against multidrug-resistant cancer cells. European Journal of Cancer Supplements. 8(7). 76–77. 1 indexed citations

Miller, Michael L., Nathan Fishkin, Wěi Li, et al.. (2009). Abstract B126: Potent antigen-specific anti-tumor activity observed with antibody-drug conjugates (ADCs) made using a new class of DNA-crosslinking agents. Molecular Cancer Therapeutics. 8(12_Supplement). B126–B126. 5 indexed citations

Erickson, Hans K., Sharon Wilhelm, Wayne C. Widdison, et al.. (2008). Evaluation of the cytotoxic potencies of the major maytansinoid metabolites of antibody maytansinoid conjugates detected in vitro and in preclinical mouse models. Cancer Research. 68. 2150–2150. 4 indexed citations

Widdison, Wayne C., Sharon Wilhelm, Kathleen R. Whiteman, et al.. (2006). Semisynthetic Maytansine Analogues for the Targeted Treatment of Cancer. Journal of Medicinal Chemistry. 49(14). 4392–4408. 231 indexed citations

10.

Kovtun, Yelena, Charlene A. Audette, Yumei Ye, et al.. (2006). Antibody-Drug Conjugates Designed to Eradicate Tumors with Homogeneous and Heterogeneous Expression of the Target Antigen. Cancer Research. 66(6). 3214–3221. 342 indexed citations

11.

Dezube, Bruce J., John P. Doweiko, Brian Conway, et al.. (2004). Monoclonal antibody hNM01 in HIV-infected patients: a phase I study. Journal of Clinical Virology. 31. 45–47. 9 indexed citations

12.

Miller, Michael L., et al.. (2004). Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies. Bioorganic & Medicinal Chemistry Letters. 14(15). 4079–4082. 11 indexed citations

13.

Baloglu, Erkan, et al.. (2004). Synthesis and biological evaluation of novel taxoids designed for targeted delivery to tumors. Bioorganic & Medicinal Chemistry Letters. 14(23). 5885–5888. 15 indexed citations

14.

Miller, Michael L., Robert Y. Zhao, Barbara A. Leece, et al.. (2004). Synthesis of Taxoids with Improved Cytotoxicity and Solubility for Use in Tumor-Specific Delivery. Journal of Medicinal Chemistry. 47(20). 4802–4805. 19 indexed citations

15.

Ojima, Iwao, Xu Geng, X. Ben Wu, et al.. (2002). Tumor-Specific Novel Taxoid−Monoclonal Antibody Conjugates. Journal of Medicinal Chemistry. 45(26). 5620–5623. 88 indexed citations

16.

Durda, Paul J., Lee T. Bacheler, Paul R. Clapham, et al.. (1990). HIV-1 Neutralizing Monoclonal Antibodies Induced by a Synthetic Peptide. AIDS Research and Human Retroviruses. 6(9). 1115–1123. 40 indexed citations

17.

Durda, Paul J., et al.. (1988). Characterization of Murine Monoclonal Antibodies to HIV-1 Induced by Synthetic Peptides. AIDS Research and Human Retroviruses. 4(5). 331–342. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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