Paul R. Clapham

17.6k total citations · 5 hit papers
127 papers, 14.4k citations indexed

About

Paul R. Clapham is a scholar working on Virology, Immunology and Infectious Diseases. According to data from OpenAlex, Paul R. Clapham has authored 127 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 104 papers in Virology, 75 papers in Immunology and 47 papers in Infectious Diseases. Recurrent topics in Paul R. Clapham's work include HIV Research and Treatment (104 papers), Immune Cell Function and Interaction (51 papers) and HIV/AIDS drug development and treatment (36 papers). Paul R. Clapham is often cited by papers focused on HIV Research and Treatment (104 papers), Immune Cell Function and Interaction (51 papers) and HIV/AIDS drug development and treatment (36 papers). Paul R. Clapham collaborates with scholars based in United Kingdom, United States and Germany. Paul R. Clapham's co-authors include Angus Dalgleish, Robin A. Weiss, Robin A. Weiss, Peter C. L. Beverley, Dorothy H. Crawford, Melvyn F. Greaves, Áine McKnight, Graham Simmons, Paul J. Maddon and J. Steven McDougal and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Paul R. Clapham

126 papers receiving 13.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 2.9k citations Angus Dalgleish, Paul R. Clapham et al. profile →
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 1.7k citations Angus Dalgleish, Paul R. Clapham et al. profile →
CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

1996 598 citations Paul R. Clapham, Mark Marsh et al. profile →
Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

1997 508 citations Graham Simmons, Paul R. Clapham et al. profile →
Identification of the residues in human CD4 critical for the binding of HIV

1989 320 citations James Arthos, Quentin J. Sattentau et al. profile →

Peers

Countries citing papers authored by Paul R. Clapham

Since Specialization

Citations

This map shows the geographic impact of Paul R. Clapham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul R. Clapham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul R. Clapham more than expected).

Fields of papers citing papers by Paul R. Clapham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul R. Clapham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul R. Clapham. The network helps show where Paul R. Clapham may publish in the future.

Co-authorship network of co-authors of Paul R. Clapham

This figure shows the co-authorship network connecting the top 25 collaborators of Paul R. Clapham. A scholar is included among the top collaborators of Paul R. Clapham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul R. Clapham. Paul R. Clapham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Implications of the 375W mutation for HIV-1 tropism and vaccine development 2024 ·Journal of Virology ·(unknown), (unknown), (unknown), Paul R. Clapham, Maria José Duenas-Decamp	0
2	No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications 2018 ·Archives of Virology ·(unknown), Paul J. Peters, Matthew Koch, Katherine Luzuriaga, Cecilia Cheng‐Mayer, Paul R. Clapham, (unknown)	1
3	Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality 2017 ·PLoS Pathogens ·(unknown), Peter Rusert, Carsten Magnus, Claus Kadelka, Jacqueline Weber, Therese Uhr, Osvaldo Zagordi, (unknown), Maria José Duenas-Decamp, Paul R. Clapham, Karin J. Metzner, Huldrych F. Günthard, Alexandra Trkola	26
4	Two Closely Related Env Antigens from the Same Patient Elicited Different Spectra of Neutralizing Antibodies against Heterologous HIV-1 Isolates 2011 ·Journal of Virology ·Michael Vaine, Maria José Duenas-Decamp, Paul J. Peters, Qin Liu, James Arthos, Shixia Wang, Paul R. Clapham, Shan Lu	10
5	Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors 2008 ·Retrovirology ·Paul J. Peters, Maria José Duenas-Decamp, Wendy Sullivan, Richard J. P. Brown, (unknown), Katherine Luzuriaga, James E. Robinson, Dennis R. Burton, Jeanne E. Bell, Peter Simmonds, Jonathan K. Ball, Paul R. Clapham	73
6	Lack of alternative coreceptor use by pediatric HIV-1 R5 isolates for infection of primary cord or adult peripheral blood mononuclear cells 2007 ·Archives of Virology ·(unknown), Patrick Dorr, Manos Perros, (unknown), Jean Leif, Katherine Luzuriaga, Paul R. Clapham	3
7	Use of alternate coreceptors on primary cells by two HIV-1 isolates 2005 ·Virology ·Tonie Cilliers, (unknown), (unknown), (unknown), Pavel Pugach, Mia Coetzer, Maria A. Papathanasopoulos, John P. Moore, Alexandra Trkola, Paul R. Clapham, Lynn Morris	29
8	Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells 2001 ·AIDS ·Annapurna Vyakarnam, (unknown), Ian Teo, Mark Zuckerman, Kaboutar Babaahmady, Hanneke Schuitemaker, Sunil Shaunak, Timothy Rostron, Sarah Rowland‐Jones, Graham Simmons, Paul R. Clapham	10
9	Comparison of CD4-independent infection by HIV-1, HIV-2 and SIV strains, and relevance of receptors other than CCR5 and CXCR4 for infection of primary cell types 2000 ·Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) ·Jacqueline D. Reeves, Graham Simmons, Nathalie Dejucq‐Rainsford, Sam Hibbitts, Áine McKnight, (unknown), José Moniz‐Pereira, Paul R. Clapham	1
10	Differential Activation of CC Chemokine Receptors by AOP-RANTES 2000 ·Journal of Biological Chemistry ·Jörn Elsner, Matthias Mack, Hilke Brühl, (unknown), Daniela Kimmig, Graham Simmons, Paul R. Clapham, Detlef Schlöndorff, Alexander Kapp, Timothy N. C. Wells, Amanda E. I. Proudfoot	63
11	Co‐receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands 2000 ·Immunological Reviews ·Graham Simmons, Jacqueline D. Reeves, Sam Hibbitts, Johnny T. Stine, Patrick W. Gray, Amanda E. I. Proudfoot, Paul R. Clapham	103
12	A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3 2000 ·Journal of Biological Chemistry ·Ian Sabroe, Michael J. Peck, (unknown), Annelies Jorritsma, Graham Simmons, Paul R. Clapham, Timothy J. Williams, James E. Pease	161
13	The second extracellular loop of CXCR4 is involved in CD4-independent entry of human immunodeficiency virus type 2. 1998 ·Journal of General Virology ·Jacqueline D. Reeves, Anne Brelot, L Picard, Marc Alizon, Paul R. Clapham, (unknown)	25
14	Cell-to-Cell Fusion, but Not Virus Entry in Macrophages by T-Cell Line Tropic HIV-1 Strains: A V3 Loop-Determined Restriction 1995 ·Virology ·Graham Simmons, Áine McKnight, Yasuhiro Takeuchi, Hiroo Hoshino, Paul R. Clapham	36
15	Immune escape and tropism of HIV 1995 ·Trends in Microbiology ·Áine McKnight, Paul R. Clapham	27
16	Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection 1993 ·Philosophical Transactions of the Royal Society B Biological Sciences ·Paul R. Clapham, Áine McKnight, Graham Simmons, Robin A. Weiss	6
17	The V3 Loops of the HIV-1 and HTV-2 Surface Glycoproteins Contain Proteolytic Cleavage Sites: A Possible Function in Viral Fusion? 1991 ·AIDS Research and Human Retroviruses ·Gary Clements, Molly Price-Jones, Paul E. Stephens, Chris W. Sutton, Thomas F. Schulz, Paul R. Clapham, Jane A. McKeating, Myra O. McClure, (unknown), Mark Marsh, John Kay, Robin A. Weiss, John P. Moore	219
18	Enhancement of Soluble CD4-Mediated HIV Neutralization and gp120 Binding by CD4 Autoantibodies and Monoclonal Antibodies 1990 ·AIDS Research and Human Retroviruses ·John P. Moore, Quentin J. Sattentau, Paul R. Clapham	18
19	HIV-1 Neutralizing Monoclonal Antibodies Induced by a Synthetic Peptide 1990 ·AIDS Research and Human Retroviruses ·Paul J. Durda, Lee T. Bacheler, Paul R. Clapham, (unknown), Barbara A. Leece, Thomas J. Matthews, Áine McKnight, Roger J. Pomerantz, Marlene M. Rayner, Kent J. Weinhold	40
20	Neutralization of diverse HIV-1 strains by monoclonal antibodies raised against a gp41 synthetic peptide 1988 ·Virology ·Angus Dalgleish, Tran C. Chanh, Ronald C. Kennedy, Patrick Kanda, Paul R. Clapham, Robin A. Weiss	107

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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