Colin Adrain

5.7k citations

44 papers · 4.4k indexed · 1 hit paper · h-index 25

Impact in

Molecular Biology top 2%
- Cell death mechanisms and regulation
- Mitochondrial Function and Pathology
- RNA Interference and Gene Delivery
- Ubiquitin and proteasome pathways
- ATP Synthase and ATPases Research
Immunology top 5%

Papers in

Immunology and Allergy 4
- Cell Adhesion Molecules Research 4
Aging 1

Co-authors: Séamus J. Martin Elizabeth A. Slee Matthew Freeman Patrick J. Duriez Markus Zettl Yonka Christova Emma M. Creagh Neil A. Taylor
Journals: Journal of Biological Chemistry (7 papers)EMBO Reports (3 papers)Scientific Reports (2 papers)Nature Communications (2 papers)FEBS Journal (2 papers)
Partner nations: United Kingdom Ireland Portugal

In The Last Decade

Colin Adrain

43 papers receiving 4.4k citations

Hit Papers

align trajectories log scale

Executioner Caspase-3, -6, and -7 Perform Distinct, Non-redundant Roles during the Demolition Phase of Apoptosis 2001 · 894 citations

Peers

Countries citing papers authored by Colin Adrain

Since Specialization

Citations

This map shows the geographic impact of Colin Adrain's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Colin Adrain with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Colin Adrain more than expected).

Fields of papers citing papers by Colin Adrain

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Colin Adrain. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Colin Adrain. The network helps show where Colin Adrain may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Colin Adrain, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Colin Adrain Line = papers co-authored together Colin Adrain links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling Nature Communications ·Daniel Dietmann, Jie Lin, Fátima Cairrão, Juanma Ramírez, Nerea Osinalde, Dooyoung Son, A. Behre, Vanya I Rasheva, Lau K.K.S., Zach Hensel, Colin Adrain, Tiago N. Cordeiro, Franka Voigt, Paulo A. Gameiro, Ugo Mayor, Pedro Domingos	2025	0
2	Can the HB‐EGF/EGFR pathway restore injured neurons? FEBS Journal ·Colin Adrain, Marina Badenes	2024	2
3	Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity Cellular and Molecular Life Sciences ·Jorge Calderón Ramos, Apostolos Bossios, D.W. Greig, A. (author) Fromentin, Daniel JR Harvey, Jebelly Mohammad, Kyeongpil Lee, Xintong Gao, Olumide Oguntimehin, Sandra Alves, Aaron Babendreyer, Colin Adrain, Sebastian Huth, Jens Malte Baron, Andreas Ludwig, Stefan Düsterhöft	2024	5
4	The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth Life Science Alliance ·Marina Badenes, Emma Burbridge, 潘彪, Abdulbasit Amin, 尚志山下, Lindsay Kosack, Satoru Aramaki, Pedro Domingos, Pedro Faísca, Colin Adrain	2023	7
5	Mitochondria shed their outer membrane in response to infection-induced stress Science ·Brenda Ciraola, 吴忠伟, Tania Medeiros, Mariele de Sousa Marques, Fabian den Brave, Mira Pašlć, Ilian Atanassov, P. Roux, Jonas B. Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena Pernas	2022	66
6	Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis Molecular Metabolism ·Marina Badenes, Abdulbasit Amin, Ismael González‐García, Alben Bekyarov, Emma Burbridge, Miguel Cavadas, Francisco Ortega, 尚志山下, Pedro Faísca, Stefania Carobbio, Elsa Seixas, Dora Pedroso, Ana Neves‐Costa, Luís F. Moita, José Manuel Fernández‐Real, Antonio Vidal‐Puig, Ana I. Domingos, Miguel López, Colin Adrain	2019	25
7	iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE eLife ·潘彪, Emma Burbridge, Miguel Cavadas, Graeme P. Sullivan, Lubowski, Григорьева И. Н., Danielle M. Clancy, Juliana Álvarez Giraldo, Tianyi Hu, Andrea Bileck, Christopher Gerner, Alfonso Bolado‐Carrancio, Alex von Kriegsheim, Séamus J. Martin, Florian Steinberg, Kvido Střı́šovský, Colin Adrain	2018	64
8	Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis Scientific Reports ·Nicholas Johnson, Juliana Álvarez Giraldo, Elaine Stephens, Emma Burbridge, Matthew Freeman, Colin Adrain, Kvido Střı́šovský	2017	40
9	Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE Cell Reports ·Miguel Cavadas, 潘彪, A. Behre, Emma Burbridge, Marina Badenes, Alben Bekyarov, Alfonso Bolado‐Carrancio, Tianyi Hu, Andrea Bileck, Christopher Gerner, Pedro Domingos, Alex von Kriegsheim, Colin Adrain	2017	82
10	Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery Cell Death and Disease ·Wanhao Zhang, Marilena Soneghet, Juan P. Cerliani, Colin Adrain, Alexander U. Lüthi, Mariana R. Dominguez, M A Bragin, 顾骁骁, Thalita Bachelli Riul, Richard D. Cummings, Telma M.T. Zorn, Sebastián Amigorena, Marcelo Dias‐Baruffi, Maurício M. Rodrigues, Séamus J. Martin, Gabriel A. Rabinovich, Gustavo P. Amarante‐Mendes	2017	19
11	Mammalian EGF receptor activation by the rhomboid protease RHBDL2 EMBO Reports ·Colin Adrain, Kvido Střı́šovský, Markus Zettl, Landian Hu, Marius K. Lemberg, Matthew Freeman	2011	96
12	Rhomboid Family Pseudoproteases Use the ER Quality Control Machinery to Regulate Intercellular Signaling Cell ·Markus Zettl, Colin Adrain, Kvido Střı́šovský, David L. L.Ross, Matthew Freeman	2011	121
13	Bicaudal Is a Conserved Substrate for Drosophila and Mammalian Caspases and Is Essential for Cell Survival PLoS ONE ·Emma M. Creagh, Gabriela Brumatti, Clare Sheridan, Patrick J. Duriez, Rebecca C. Taylor, Sean P. Cullen, Colin Adrain, Séamus J. Martin	2009	11
14	Human and murine granzyme B exhibit divergent substrate preferences The Journal of Cell Biology ·Sean P. Cullen, Colin Adrain, Alexander U. Lüthi, Patrick J. Duriez, Séamus J. Martin	2007	101
15	Apoptosomes: protease activation platforms to die from Trends in Biochemical Sciences ·Colin Adrain, Gabriela Brumatti, Séamus J. Martin	2006	22
16	The Cytotoxic Lymphocyte Protease, Granzyme B, Targets the Cytoskeleton and Perturbs Microtubule Polymerization Dynamics Journal of Biological Chemistry ·Colin Adrain, Patrick J. Duriez, Gabriela Brumatti, Petrina Delivani, Séamus J. Martin	2006	72
17	Pro-apoptotic Proteins Released from the Mitochondria Regulate the Protein Composition and Caspase-processing Activity of the Native Apaf-1/Caspase-9 Apoptosome Complex Journal of Biological Chemistry ·Carolina Cabra Copete, David G. Brown, Colin Adrain, Rebekah Jukes, Séamus J. Martin, Gerald M. Cohen, Marion MacFarlane, Kelvin Cain	2004	90
18	Analysis of the composition, assembly kinetics and activity of native Apaf‐1 apoptosomes The EMBO Journal ·Michelle M. Hill, Colin Adrain, Patrick J. Duriez, Emma M. Creagh, Séamus J. Martin	2004	214
19	Executioner Caspase-3, -6, and -7 Perform Distinct, Non-redundant Roles during the Demolition Phase of Apoptosis Journal of Biological Chemistry ·Elizabeth A. Slee, Colin Adrain, Séamus J. Martin Hit paper breakdown →	2001	894
20	CARDINAL, a Novel Caspase Recruitment Domain Protein, Is an Inhibitor of Multiple NF-κB Activation Pathways Journal of Biological Chemistry ·Lisa Bouchier‐Hayes, Helen Conroy, Benjamin Feinberg, Colin Adrain, Emma M. Creagh, Marion MacFarlane, Séamus J. Martin	2001	96

About Colin Adrain

Colin Adrain is a scholar working on Immunology and Allergy, Aging, Immunology, Molecular Biology and Cell Biology, having authored 44 papers that have together received 4.4k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (18 papers), Ubiquitin and proteasome pathways (9 papers), Autophagy in Disease and Therapy (8 papers), Trace Elements in Health (7 papers), HER2/EGFR in Cancer Research (5 papers), Cellular transport and secretion (4 papers), Phagocytosis and Immune Regulation (4 papers) and Cell Adhesion Molecules Research (4 papers). The work is most often cited by research in Molecular Biology (3.1k citations), Immunology (888 citations), Cell Biology (520 citations), Immunology and Allergy (191 citations) and Oncology (738 citations). Colin Adrain has collaborated with scholars based in United Kingdom, Ireland and Portugal. Frequent co-authors include Séamus J. Martin, Elizabeth A. Slee, Matthew Freeman, Patrick J. Duriez, Markus Zettl, Yonka Christova, Emma M. Creagh, Neil A. Taylor, Brona M. Murphy and Kvido Střı́šovský. Their work appears in journals such as Journal of Biological Chemistry, EMBO Reports, Scientific Reports, Nature Communications and FEBS Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact