Lynne Howells

5.0k total citations · 3 hit papers
62 papers, 3.9k citations indexed

About

Lynne Howells is a scholar working on Molecular Biology, Oncology and Molecular Medicine. According to data from OpenAlex, Lynne Howells has authored 62 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 27 papers in Oncology and 18 papers in Molecular Medicine. Recurrent topics in Lynne Howells's work include Curcumin's Biomedical Applications (18 papers), Genomics, phytochemicals, and oxidative stress (11 papers) and Natural product bioactivities and synthesis (8 papers). Lynne Howells is often cited by papers focused on Curcumin's Biomedical Applications (18 papers), Genomics, phytochemicals, and oxidative stress (11 papers) and Natural product bioactivities and synthesis (8 papers). Lynne Howells collaborates with scholars based in United Kingdom, United States and Iraq. Lynne Howells's co-authors include Margaret M. Manson, Karen Brown, Andreas J. Gescher, Simon Plummer, W P Steward, Karen Holloway, Stuart Farrow, Allard Kaptein, R. J. L. Munks and Anne Thomas and has published in prestigious journals such as PLoS ONE, Diabetes Care and Cancer Research.

In The Last Decade

Lynne Howells

61 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex

1999 539 citations Simon Plummer, Karen Holloway et al. Oncogene profile →
Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.

2001 506 citations Donald J. L. Jones, Richard D. Verschoyle et al. profile →
Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps and Opportunities

2024 75 citations Karen Brown, Robert G. Britton et al. International Journal of Molecular Sciences profile →

Peers

Countries citing papers authored by Lynne Howells

Since Specialization

Citations

This map shows the geographic impact of Lynne Howells's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lynne Howells with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lynne Howells more than expected).

Fields of papers citing papers by Lynne Howells

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lynne Howells. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lynne Howells. The network helps show where Lynne Howells may publish in the future.

Co-authorship network of co-authors of Lynne Howells

This figure shows the co-authorship network connecting the top 25 collaborators of Lynne Howells. A scholar is included among the top collaborators of Lynne Howells based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lynne Howells. Lynne Howells is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Clinical Validation of Local Versus Commercial Genomic Testing in Cancer: A Comparison of Tissue and Plasma Concordance 2025 ·Cancer Investigation ·(unknown), Lynne Howells, Susann Lehmann, Caroline Cowley, (unknown), Jacqui Shaw, Anne Thomas	1
2	Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps and Opportunities breakdown → 2024 ·International Journal of Molecular Sciences ·Karen Brown, (unknown), Robert G. Britton, (unknown), Coral Pepper, (unknown), Lynne Howells	75
3	Clinical trials in cancer screening, prevention and early diagnosis (SPED): a systematic mapping review 2023 ·BMC Cancer ·Emma O’Dowd, Samuel WD Merriel, Vinton W.T. Cheng, Sam Khan, Lynne Howells, Dipesh P Gopal, (unknown), Paul M. Brennan, Philip Crosbie, Richard D Neal, Karen Brown, Emma J. Crosbie, David Baldwin	5
4	The utility of ctDNA in detecting minimal residual disease following curative surgery in colorectal cancer: a systematic review and meta-analysis 2022 ·British Journal of Cancer ·(unknown), Lynne Howells, Coral Pepper, Jacqui Shaw, Anne Thomas	38
5	Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells 2022 ·PLoS ONE ·(unknown), (unknown), Inna Guterman, (unknown), Kevin West, (unknown), Hong Cai, Constantia Alexandrou, (unknown), (unknown), Lynne Howells, Jennifer A. Higgins, Donald J. L. Jones, Rajinder Singh, Robert G. Britton, Cristina Tufarelli, Anne Thomas, Alessandro Rufini	17
6	A Systematic Review Assessing Clinical Utility of Curcumin with a Focus on Cancer Prevention 2021 ·Molecular Nutrition & Food Research ·Lynne Howells, (unknown), (unknown), Coral Pepper, Anne Thomas, Karen Brown, Sameena Khan	20
7	Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients 2021 ·Journal of Visualized Experiments ·Giuditta Viticchiè, Ian Powley, (unknown), (unknown), Michael Butterworth, (unknown), (unknown), Gareth J. Miles, Lynne Howells, (unknown), Marion MacFarlane, Catrin Pritchard	5
8	Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants 2020 ·Laboratory Investigation ·Gareth J. Miles, Ian Powley, Seid Mohammed, Lynne Howells, J. H. Pringle, Tim Hammonds, Marion MacFarlane, Catrin Pritchard	8
9	Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial 2019 ·Journal of Nutrition ·Lynne Howells, Chinenye Iwuji, (unknown), Shaun Barber, Harriet S. Walter, (unknown), (unknown), Raj Singh, (unknown), Samita R. Patel, Bruno Morgan, William P. Steward, Andreas J. Gescher, Anne Thomas, Karen Brown	181
10	Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity 2018 ·Cell Death and Disease ·(unknown), Ajay Verma, Daniel Fernández-García, Panchali Sarmah, Patrick Tarpey, (unknown), Hong Cai, Ricky M. Trigg, Kevin West, Lynne Howells, Anne Thomas, Karen Brown, David S. Guttery, Baljit Singh, (unknown), Ultan McDermott, Jacqui Shaw, Alessandro Rufini	38
11	An HPLC‐UV method for the simultaneous quantification of curcumin and its metabolites in plasma and lung tissue: Potential for preclinical applications 2018 ·Biomedical Chromatography ·(unknown), Lynne Howells, Rajinder Singh, Robert G. Britton, Hong Cai, Karen Brown	13
12	Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes 2018 ·Scientific Reports ·Constantia Alexandrou, (unknown), Jennifer A. Higgins, William Boyle, Ankur Karmokar, Catherine Andreadi, Jinli Luo, David A. Moore, Maria Viskaduraki, Matthew Blades, Graeme I. Murray, Lynne Howells, Anne Thomas, Karen Brown, Paul N. Cheng, Alessandro Rufini	67
13	Potential for Proteomic Approaches in Determining Efficacy Biomarkers Following Administration of Fish Oils Rich in Omega‐3 Fatty Acids 2015 ·Nutrition in Clinical Practice ·(unknown), Ali Arshad, John Isherwood, (unknown), Lynne Howells, Matthew S. Metcalfe, Ashley R. Dennison	3
14	Cancer chemoprevention 2014 ·European Journal of Cancer Prevention ·Chinenye Iwuji, Lynne Howells, Sarah Thomasset, Karen Brown, William P. Steward, Julian Barwell, Anne Thomas	2
15	Curcumin ameliorates oxaliplatin‐induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo 2010 ·International Journal of Cancer ·Lynne Howells, Stewart Sale, (unknown), (unknown), Donald J. L. Jones, Christopher J. Ottley, D. Graham Pearson, Christopher D. Mann, Margaret M. Manson, David P. Berry, Andreas J. Gescher, William P. Steward, Karen Brown	77
16	Comparison of oxaliplatin‐ and curcumin‐mediated antiproliferative effects in colorectal cell lines 2007 ·International Journal of Cancer ·Lynne Howells, Anita Mitra, Margaret M. Manson	83
17	Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity 2004 ·British Journal of Cancer ·Donald J. L. Jones, John H. Lamb, Richard D. Verschoyle, Lynne Howells, Michael Butterworth, C.K. Lim, D. Ferry, P. B. Farmer, Andreas J. Gescher	43
18	Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells 2003 ·Biochemical Pharmacology ·Matthew Squires, E A Hudson, Lynne Howells, Stewart Sale, Catherine Houghton, J. Louise Jones, (unknown), Martin Dickens, Sally A. Prigent, Margaret M. Manson	166
19	Differences between human breast cell lines in susceptibility towards growth inhibition by genistein 2001 ·British Journal of Cancer ·(unknown), E A Hudson, Lynne Howells, Margaret M. Manson, R A Walker, Andreas J. Gescher	60
20	Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex breakdown → 1999 ·Oncogene ·Simon Plummer, Karen Holloway, Margaret M. Manson, R. J. L. Munks, Allard Kaptein, Stuart Farrow, Lynne Howells	539

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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