Liesbeth van Deemter

11.2k citations

24 papers · 9.1k indexed · 6 hit papers · h-index 23

Oncology top 0.1%
Pediatrics, Perinatology and Child Health top 0.1%
Molecular Biology top 2%
Surgery top 2%
Infectious Diseases top 1%

Co-authors: Alfred H. Schinkel Els Wagenaar Carla A.A.M. Mol Piet Borst Martin A. van der Valk Jasper Smit Anton Berns Olaf van Tellingen
Topics: Drug Transport and Resistance Mechanisms (18 papers)Pharmacological Effects and Toxicity Studies (15 papers)Pediatric Hepatobiliary Diseases and Treatments (7 papers)
Cited by: Oncology Pediatrics, Perinatology and Child Health Pharmacology
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: Netherlands United States Germany

In The Last Decade

Liesbeth van Deemter

24 papers receiving 8.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1994 1.8k citations Alfred H. Schinkel, Jasper Smit et al. Cell profile →
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1993 1.2k citations Jasper Smit, Alfred H. Schinkel et al. Cell profile →
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

1996 1.0k citations Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation profile →
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1995 957 citations Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation profile →
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1997 771 citations Alfred H. Schinkel, Ulrich Mayer et al. Proceedings of the National Academy of Sciences profile →
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

1998 529 citations Raymond Evers, Marcel Kool et al. Journal of Clinical Investigation profile →

Peers

Countries citing papers authored by Liesbeth van Deemter

Since Specialization

Citations

This map shows the geographic impact of Liesbeth van Deemter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Liesbeth van Deemter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Liesbeth van Deemter more than expected).

Fields of papers citing papers by Liesbeth van Deemter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Liesbeth van Deemter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Liesbeth van Deemter. The network helps show where Liesbeth van Deemter may publish in the future.

Co-authorship network of co-authors of Liesbeth van Deemter

This figure shows the co-authorship network connecting the top 25 collaborators of Liesbeth van Deemter. A scholar is included among the top collaborators of Liesbeth van Deemter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Liesbeth van Deemter. Liesbeth van Deemter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1 -Mutated Mouse Mammary Tumors 2012 ·Cancer Discovery ·Janneke E. Jaspers,Ariena Kersbergen,Ute Boon,Wendy Sol,Liesbeth van Deemter,Serge A.L. Zander,Rinske Drost,Ellen Wientjens,Jiuping Ji,(unknown),James H. Doroshow,Aaron Cranston,Niall M.B. Martin,Alan Lau,Mark J. O’Connor,Shridar Ganesan,Piet Borst,Jos Jonkers,Sven Rottenberg	388
2	Characterization of the Transport of Nucleoside Analog Drugs by the Human Multidrug Resistance Proteins MRP4 and MRP5 2003 ·Molecular Pharmacology ·Glen Reid,Peter R. Wielinga,Noam Zelcer,Marcel de Haas,Liesbeth van Deemter,Jan Wijnholds,Jan Balzarini,Piet Borst	300
3	Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells 2002 ·Molecular Pharmacology ·Peter R. Wielinga,Glen Reid,(unknown),Ingrid van der Heijden,Liesbeth van Deemter,Marcel de Haas,Carla A.A.M. Mol,Annemieke Kuil,Els Groeneveld,John D. Schuetz,C. Brouwer,Ronney A. De Abreu,Jan Wijnholds,Jos H. Beijnen,Piet Borst	149
4	Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. 2000 ·PubMed ·John Allen,(unknown),Liesbeth van Deemter,Jan Wijnholds,Alfred H. Schinkel	168
5	Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport 2000 ·British Journal of Cancer ·Raymond Evers,Marcel Kool,Alexander J. Smith,Liesbeth van Deemter,Marcel de Haas,Piet Borst	185
6	Role of blood‐brain barrier P‐glycoprotein in limiting brain accumulation and sedative side‐effects of asimadoline, a peripherally acting analgaesic drug 1999 ·British Journal of Pharmacology ·Johan W. Jonker,Els Wagenaar,Liesbeth van Deemter,Rudolf Gottschlich,(unknown),Johannes Dasenbrock,Alfred H. Schinkel	87
7	Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.breakdown → 1998 ·Journal of Clinical Investigation ·Raymond Evers,Marcel Kool,Liesbeth van Deemter,Hans Janssen,Jero Calafat,Lauran C. J. M. Oomen,Coen C. Paulusma,Ronald P.J. Oude Elferink,Frank Baas,Alfred H. Schinkel,Piet Borst	529
8	Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain 1998 ·Journal of Biological Chemistry ·Éva Bakos,Raymond Evers,Gergely Szakács,Gábor Tusnády,Ervin Welker,Katalin Szabó,Marcel de Haas,Liesbeth van Deemter,Piet Borst,András Váradi,Balázs Sarkadi	270
9	Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteinsbreakdown → 1997 ·Proceedings of the National Academy of Sciences ·Alfred H. Schinkel,Ulrich Mayer,Els Wagenaar,Carla A.A.M. Mol,Liesbeth van Deemter,(unknown),Martin A. van der Valk,Arie C. Voordouw,Hergen Spits,Olaf van Tellingen,J. M. J. M. Zijlmans,Willem E. Fibbe,Piet Borst	771
10	Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1 1997 ·FEBS Letters ·Raymond Evers,Nicole H.P. Cnubben,Jan Wijnholds,Liesbeth van Deemter,Peter J. van Bladeren,Piet Borst	112
11	Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. 1996 ·Journal of Clinical Investigation ·Raymond Evers,Guido J.R. Zaman,Liesbeth van Deemter,H W Jansen,Jero Calafat,Lauran C. J. M. Oomen,Ronald P.J. Oude Elferink,Piet Borst,Alfred H. Schinkel	224
12	P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.breakdown → 1996 ·Journal of Clinical Investigation ·Alfred H. Schinkel,Els Wagenaar,Carla A.A.M. Mol,Liesbeth van Deemter	1032
13	Multidrug resistance and the role of P-glycoprotein knockout mice 1995 ·European Journal of Cancer ·Alfred H. Schinkel,Carla A.A.M. Mol,Els Wagenaar,Liesbeth van Deemter,Jasper Smit,Piet Borst	154
14	Characterization of the promoter region of the human MDR3 P-glycoprotein gene 1995 ·Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·(unknown),Carla A.A.M. Mol,Liesbeth van Deemter,Els Wagenaar,Alfred H. Schinkel,Piet Borst	20
15	Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.breakdown → 1995 ·Journal of Clinical Investigation ·Alfred H. Schinkel,Els Wagenaar,Liesbeth van Deemter,Carla A.A.M. Mol,Piet Borst	957
16	Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsbreakdown → 1994 ·Cell ·Alfred H. Schinkel,Jasper Smit,Olaf van Tellingen,Jos H. Beijnen,Els Wagenaar,Liesbeth van Deemter,Carla A.A.M. Mol,Martin A. van der Valk,Els C. Robanus-Maandag,Hein P. J. te Riele,Anton Berns,Piet Borst	1812
17	Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals 1993 ·Pharmacology & Therapeutics ·Piet Borst,Alfred H. Schinkel,Jasper Smit,Els Wagenaar,Liesbeth van Deemter,A. J. Smith,(unknown),Frank Baas,G J Zaman	145
18	Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver diseasebreakdown → 1993 ·Cell ·Jasper Smit,Alfred H. Schinkel,Ronald P.J. Oude Elferink,Albert K. Groen,Els Wagenaar,Liesbeth van Deemter,Carla A.A.M. Mol,R. Ottenhoff,Nathalie M. T. van der Lugt,Marian A. van Roon,Martin A. van der Valk,G. J. A. Offerhaus,Anton Berns,Piet Borst	1180
19	Transient Expression of the Proto-Oncogene int-1 during Differentiation of P19 Embryonal Carcinoma Cells 1989 ·Molecular and Cellular Biology ·Ed Schuuring,Liesbeth van Deemter,Henk Roelink,Roel Nusse	31
20	Identification of the Mtv -2 gene responsible for the early appearance of mammary tumors in the GR mouse by nucleic acid hybridization 1978 ·Proceedings of the National Academy of Sciences ·Rob Michalides,Liesbeth van Deemter,Roel Nusse,R. Van Nie	40

About Liesbeth van Deemter

Liesbeth van Deemter is a scholar working on Pediatrics, Perinatology and Child Health, Oncology and Transplantation, having authored 24 papers that have together received 9.1k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (18 papers), Pharmacological Effects and Toxicity Studies (15 papers) and Pediatric Hepatobiliary Diseases and Treatments (7 papers). The work is most often cited by research in Oncology (7.1k citations), Pediatrics, Perinatology and Child Health (3.7k citations) and Pharmacology (900 citations). Liesbeth van Deemter has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include Alfred H. Schinkel, Els Wagenaar, Carla A.A.M. Mol, Piet Borst, Martin A. van der Valk, Jasper Smit, Anton Berns, Olaf van Tellingen, Jos H. Beijnen and Ronald P.J. Oude Elferink. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact