Carla A.A.M. Mol

9.5k total citations · 5 hit papers
16 papers, 7.8k citations indexed

About

Carla A.A.M. Mol is a scholar working on Oncology, Pediatrics, Perinatology and Child Health and Surgery. According to data from OpenAlex, Carla A.A.M. Mol has authored 16 papers receiving a total of 7.8k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Oncology, 10 papers in Pediatrics, Perinatology and Child Health and 5 papers in Surgery. Recurrent topics in Carla A.A.M. Mol's work include Drug Transport and Resistance Mechanisms (14 papers), Pharmacological Effects and Toxicity Studies (10 papers) and Pediatric Hepatobiliary Diseases and Treatments (5 papers). Carla A.A.M. Mol is often cited by papers focused on Drug Transport and Resistance Mechanisms (14 papers), Pharmacological Effects and Toxicity Studies (10 papers) and Pediatric Hepatobiliary Diseases and Treatments (5 papers). Carla A.A.M. Mol collaborates with scholars based in Netherlands, United States and Germany. Carla A.A.M. Mol's co-authors include Alfred H. Schinkel, Liesbeth van Deemter, Els Wagenaar, Piet Borst, Martin A. van der Valk, Jasper Smit, Anton Berns, Jos H. Beijnen, Olaf van Tellingen and Hein P. J. te Riele and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

In The Last Decade

Carla A.A.M. Mol

16 papers receiving 7.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1994 1.8k citations Alfred H. Schinkel, Jasper Smit et al. Cell profile →
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1993 1.2k citations Jasper Smit, Alfred H. Schinkel et al. Cell profile →
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

1996 1.0k citations Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation profile →
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1995 957 citations Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation profile →
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1997 771 citations Alfred H. Schinkel, Ulrich Mayer et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Carla A.A.M. Mol

Since Specialization

Citations

This map shows the geographic impact of Carla A.A.M. Mol's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carla A.A.M. Mol with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carla A.A.M. Mol more than expected).

Fields of papers citing papers by Carla A.A.M. Mol

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carla A.A.M. Mol. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carla A.A.M. Mol. The network helps show where Carla A.A.M. Mol may publish in the future.

Co-authorship network of co-authors of Carla A.A.M. Mol

This figure shows the co-authorship network connecting the top 25 collaborators of Carla A.A.M. Mol. A scholar is included among the top collaborators of Carla A.A.M. Mol based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carla A.A.M. Mol. Carla A.A.M. Mol is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

16 of 16 papers shown

#	Work	Indexed citations
1	CT-quantified emphysema in male heavy smokers: association with lung function decline 2011 ·Thorax ·Firdaus A. A. Mohamed Hoesein, Bartjan de Hoop, Pieter Zanen, Hester A. Gietema, Cas Kruitwagen, Bram van Ginneken, Ivana Išgum, Carla A.A.M. Mol, Rob J. van Klaveren, A. Dijkstra, Harry J.M. Groen, H.M. Boezen, Dirkje S. Postma, Mathias Prokop, J.-W.J. Lammers	118
2	Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells 2002 ·Molecular Pharmacology ·Peter R. Wielinga, Glen Reid, (unknown), Ingrid van der Heijden, Liesbeth van Deemter, Marcel de Haas, Carla A.A.M. Mol, Annemieke Kuil, Els Groeneveld, John D. Schuetz, C. Brouwer, Ronney A. De Abreu, Jan Wijnholds, Jos H. Beijnen, Piet Borst	149
3	Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene 2001 ·Molecular and Cellular Biology ·Johan W. Jonker, Els Wagenaar, Carla A.A.M. Mol, Marije Buitelaar, Hermann Koepsell, Johan W. Smit, Alfred H. Schinkel	168
4	Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier 2000 ·Journal of Clinical Investigation ·Jan Wijnholds, Elizabeth C. M. de Lange, George L. Scheffer, Dirk‐Jan van den Berg, Carla A.A.M. Mol, Martin van der Valk, Alfred H. Schinkel, Rik J. Scheper, D. D. Breimer, Piet Borst	282
5	Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. 2000 ·PubMed ·George L. Scheffer, Marcel Kool, Marc Heijn, Marcel de Haas, (unknown), Jan Wijnholds, Ardy van Helvoort, (unknown), Jan Hendrik Hooijberg, Carla A.A.M. Mol, Mariëtta L. van der Linden, (unknown), Paul van der Valk, Ronald P.J. Oude Elferink, Piet Borst, R J Scheper	183
6	Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs 2000 ·Proceedings of the National Academy of Sciences ·Jan Wijnholds, Carla A.A.M. Mol, Liesbeth van Deemter, Marcel de Haas, George L. Scheffer, Frank Baas, Jos H. Beijnen, Rik J. Scheper, Sigrid Hatse, Erik De Clercq, Jan Balzarini, Piet Borst	394
7	Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins breakdown → 1997 ·Proceedings of the National Academy of Sciences ·Alfred H. Schinkel, Ulrich Mayer, Els Wagenaar, Carla A.A.M. Mol, Liesbeth van Deemter, (unknown), Martin A. van der Valk, Arie C. Voordouw, Hergen Spits, Olaf van Tellingen, J. M. J. M. Zijlmans, Willem E. Fibbe, Piet Borst	771
8	Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein 1997 ·Nature Medicine ·Jan Wijnholds, Raymond Evers, (unknown), Carla A.A.M. Mol, Guido J.R. Zaman, Ulrich Mayer, Jos H. Beijnen, Martin van der Valk, Paul Krimpenfort, Piet Borst	364
9	P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. breakdown → 1996 ·Journal of Clinical Investigation ·Alfred H. Schinkel, Els Wagenaar, Carla A.A.M. Mol, Liesbeth van Deemter	1032
10	Multidrug resistance and the role of P-glycoprotein knockout mice 1995 ·European Journal of Cancer ·Alfred H. Schinkel, Carla A.A.M. Mol, Els Wagenaar, Liesbeth van Deemter, Jasper Smit, Piet Borst	154
11	Characterization of the promoter region of the human MDR3 P-glycoprotein gene 1995 ·Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·(unknown), Carla A.A.M. Mol, Liesbeth van Deemter, Els Wagenaar, Alfred H. Schinkel, Piet Borst	20
12	Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. breakdown → 1995 ·Journal of Clinical Investigation ·Alfred H. Schinkel, Els Wagenaar, Liesbeth van Deemter, Carla A.A.M. Mol, Piet Borst	957
13	Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs breakdown → 1994 ·Cell ·Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen, Jos H. Beijnen, Els Wagenaar, Liesbeth van Deemter, Carla A.A.M. Mol, Martin A. van der Valk, Els C. Robanus-Maandag, Hein P. J. te Riele, Anton Berns, Piet Borst	1812
14	Tissue distribution of the human MDR3 P-glycoprotein. 1994 ·PubMed ·Jasper Smit, Alfred H. Schinkel, Carla A.A.M. Mol, Donné Majoor, W. J. Mooi, A.P.M. Jongsma, Carsten R. Lincke, Piet Borst	126
15	Stable transformation of Trypanosoma brucei 1993 ·Molecular and Biochemical Parasitology ·Anneloor L.M.A. ten Asbroek, Carla A.A.M. Mol, Rudo Kieft, Piet Borst	46
16	Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease breakdown → 1993 ·Cell ·Jasper Smit, Alfred H. Schinkel, Ronald P.J. Oude Elferink, Albert K. Groen, Els Wagenaar, Liesbeth van Deemter, Carla A.A.M. Mol, R. Ottenhoff, Nathalie M. T. van der Lugt, Marian A. van Roon, Martin A. van der Valk, G. J. A. Offerhaus, Anton Berns, Piet Borst	1180

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