Henk Roelink

8.1k total citations · 5 hit papers
53 papers, 6.6k citations indexed

About

Henk Roelink is a scholar working on Molecular Biology, Genetics and Genetics. According to data from OpenAlex, Henk Roelink has authored 53 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Molecular Biology, 18 papers in Genetics and 7 papers in Genetics. Recurrent topics in Henk Roelink's work include Hedgehog Signaling Pathway Studies (38 papers), Developmental Biology and Gene Regulation (22 papers) and Epigenetics and DNA Methylation (10 papers). Henk Roelink is often cited by papers focused on Hedgehog Signaling Pathway Studies (38 papers), Developmental Biology and Gene Regulation (22 papers) and Epigenetics and DNA Methylation (10 papers). Henk Roelink collaborates with scholars based in United States, Netherlands and United Kingdom. Henk Roelink's co-authors include Thomas M. Jessell, Yasuto Tanabe, Roel Nusse, Karel F. Liem, Gabi Tremml, John P. Incardona, Raj P. Kapur, Susan Morton, Atsushi Kawakami and Johan Ericson and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Henk Roelink

53 papers receiving 6.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 874 citations Karel F. Liem, Gabi Tremml et al. Cell profile →
Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity

1996 750 citations Henk Roelink, Thomas M. Jessell et al. Cell profile →
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1995 739 citations Henk Roelink, Jeffery A. Porter et al. Cell profile →
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 724 citations Henk Roelink, Jill Heemskerk et al. Cell profile →
The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic hedgehog signal transduction

1998 539 citations William Gaffield, Raj P. Kapur et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Henk Roelink United States	32	6.0k	1.5k	1.1k	876	692	53	6.6k
Douglas J. Epstein United States	33	5.9k 1.0×	1.6k 1.1×	606 0.5×	553 0.6×	650 0.9×	58	6.9k
Lyle B. Zimmerman United Kingdom	19	4.1k 0.7×	895 0.6×	1.8k 1.6×	1.2k 1.3×	699 1.0×	26	6.2k
Jean M. Hébert United States	34	3.8k 0.6×	1.1k 0.7×	1.2k 1.1×	1.0k 1.2×	598 0.9×	83	5.5k
Chin Chiang United States	37	7.4k 1.2×	2.2k 1.5×	934 0.8×	852 1.0×	705 1.0×	58	8.8k
Ronald A. Conlon United States	31	4.9k 0.8×	1.0k 0.7×	616 0.6×	710 0.8×	857 1.2×	45	6.1k
Ivor Mason United Kingdom	42	4.5k 0.7×	978 0.7×	590 0.5×	818 0.9×	916 1.3×	82	5.7k
Richard M. Harland United States	37	8.0k 1.3×	1.4k 0.9×	458 0.4×	866 1.0×	1.3k 1.9×	43	8.8k
Chaya Kalcheim Israel	47	5.3k 0.9×	1.2k 0.8×	918 0.8×	1.6k 1.8×	1.0k 1.5×	95	6.8k
Ying Litingtung United States	21	5.2k 0.9×	1.5k 1.0×	538 0.5×	337 0.4×	440 0.6×	29	5.9k
Ali Hemmati‐Brivanlou United States	42	9.3k 1.6×	1.4k 0.9×	621 0.6×	1.2k 1.3×	1.1k 1.6×	58	10.2k

Countries citing papers authored by Henk Roelink

Since Specialization

Citations

This map shows the geographic impact of Henk Roelink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Henk Roelink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Henk Roelink more than expected).

Fields of papers citing papers by Henk Roelink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Henk Roelink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Henk Roelink. The network helps show where Henk Roelink may publish in the future.

Co-authorship network of co-authors of Henk Roelink

This figure shows the co-authorship network connecting the top 25 collaborators of Henk Roelink. A scholar is included among the top collaborators of Henk Roelink based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Henk Roelink. Henk Roelink is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Minin, Giulio Di, Alice Grison, Charles-Étienne Dumeau, et al.. (2022). TMED2 binding restricts SMO to the ER and Golgi compartments. PLoS Biology. 20(3). e3001596–e3001596. 12 indexed citations

Roelink, Henk, et al.. (2018). Gain-of-function Shh mutants activate Smo cell-autonomously independent of Ptch1/2 function. Mechanisms of Development. 153. 30–41. 6 indexed citations

Bijlsma, Maarten F., et al.. (2014). Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling. Nature Communications. 5(1). 4849–4849. 36 indexed citations

Damhofer, Helene, Jan Paul Medema, Veronique L. Veenstra, et al.. (2013). Assessment of the stromal contribution to Sonic Hedgehog‐dependent pancreatic adenocarcinoma. Molecular Oncology. 7(6). 1031–1042. 38 indexed citations

Shum, Alisa S.W., et al.. (2010). Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Developmental Dynamics. 239(12). 3192–3203. 11 indexed citations

Zhang, Shile, et al.. (2006). Inhibition of cGMP-Dependent Protein Kinase Reduces the Response to Sonic Hedgehog in Neuralized Embryoid Bodies. Stem Cells and Development. 15(5). 647–654. 3 indexed citations

Mizutani, Claudia Mieko, Néva P. Meyer, Henk Roelink, & Ethan Bier. (2006). Threshold-Dependent BMP-Mediated Repression: A Model for a Conserved Mechanism That Patterns the Neuroectoderm. PLoS Biology. 4(10). e313–e313. 78 indexed citations

Dooley, James, Matthew Erickson, Henk Roelink, & Andrew G. Farr. (2005). Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium. Developmental Dynamics. 233(4). 1605–1612. 27 indexed citations

Robertson, Christie P., Sarah Gibbs, & Henk Roelink. (2001). cGMP Enhances the Sonic Hedgehog Response in Neural Plate Cells. Developmental Biology. 238(1). 157–167. 26 indexed citations

10.

Gaffield, William, Yvonne Lange, Adele Cooney, et al.. (2000). Cyclopamine Inhibition of Sonic Hedgehog Signal Transduction Is Not Mediated through Effects on Cholesterol Transport. Developmental Biology. 224(2). 440–452. 81 indexed citations

11.

Roelink, Henk. (2000). Hippocampus formation: An intriguing collaboration. Current Biology. 10(7). R279–R281. 14 indexed citations

12.

Jasoni, Christine L., Anita E. Hendrickson, & Henk Roelink. (1999). Analysis of chickenWnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Developmental Dynamics. 215(3). 215–224. 72 indexed citations

13.

Jasoni, Christine L., Anita E. Hendrickson, & Henk Roelink. (1999). Analysis of chicken Wnt13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Developmental Dynamics. 215(3). 215–224. 2 indexed citations

14.

Millar, Sarah E., Karl Willert, Patricia C. Salinas, et al.. (1999). WNT Signaling in the Control of Hair Growth and Structure. Developmental Biology. 207(1). 133–149. 234 indexed citations

15.

Pringle, Nigel P., Weiping Yu, Sarah Guthrie, et al.. (1996). Determination of Neuroepithelial Cell Fate: Induction of the Oligodendrocyte Lineage by Ventral Midline Cells and Sonic Hedgehog. Developmental Biology. 177(1). 30–42. 231 indexed citations

16.

Liem, Karel F., Gabi Tremml, Henk Roelink, & Thomas M. Jessell. (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 82(6). 969–979. 874 indexed citations breakdown →

17.

Roelink, Henk, Jeffery A. Porter, Yasuto Tanabe, et al.. (1995). Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell. 81(3). 445–455. 739 indexed citations breakdown →

18.

Tanabe, Yasuto, Henk Roelink, & Thomas M. Jessell. (1995). Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation. Current Biology. 5(6). 651–658. 147 indexed citations

19.

Roelink, Henk, Jill Heemskerk, Vladimir Korzh, et al.. (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell. 76(4). 761–775. 724 indexed citations breakdown →

20.

Roelink, Henk, Jeremy Wang, Donald M. Black, Ellen Solomon, & Roel Nusse. (1993). Molecular Cloning and Chromosomal Localization to 17q21 of the Human WNT3 Gene. Genomics. 17(3). 790–792. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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