Leslie I. Grad

2.4k citations

20 papers · 1.9k indexed · h-index 19

Molecular Biology top 10%
Neurology top 1%
Genetics top 2%
Physiology top 10%
Neurology top 5%

Co-authors: Neil R. Cashman Edward Pokrishevsky Bernard D. Lemire Judith M. Silverman Ian R. Mackenzie Guy A. Rouleau Megan A. O’Neill John Ravits
Topics: Amyotrophic Lateral Sclerosis Research (12 papers)Mitochondrial Function and Pathology (7 papers)Prion Diseases and Protein Misfolding (6 papers)
Cited by: Aging Neurology Genetics
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry The Journal of Cell Biology
Partner nations: Canada Australia Germany

In The Last Decade

Leslie I. Grad

20 papers receiving 1.9k citations

Peers

Countries citing papers authored by Leslie I. Grad

Since Specialization

Citations

This map shows the geographic impact of Leslie I. Grad's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leslie I. Grad with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leslie I. Grad more than expected).

Fields of papers citing papers by Leslie I. Grad

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leslie I. Grad. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leslie I. Grad. The network helps show where Leslie I. Grad may publish in the future.

Co-authorship network of co-authors of Leslie I. Grad

This figure shows the co-authorship network connecting the top 25 collaborators of Leslie I. Grad. A scholar is included among the top collaborators of Leslie I. Grad based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leslie I. Grad. Leslie I. Grad is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1 2019 ·Journal of Biological Chemistry ·Judith M. Silverman,(unknown),(unknown),Kyung‐Mee Moon,(unknown),(unknown),Catherine M. Cowan,(unknown),R. Greg Stacey,Leslie I. Grad,Luke McAlary,Ian R. Mackenzie,Leonard J. Foster,Neil R. Cashman	128
2	Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites 2018 ·The Journal of Cell Biology ·Björn D. M. Bean,(unknown),Kathleen Kolehmainen,(unknown),Waldan K. Kwong,Leslie I. Grad,Michael Davey,(unknown),Elizabeth Conibear	114
3	Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture 2017 ·Methods in molecular biology ·Leslie I. Grad,Edward Pokrishevsky,Neil R. Cashman	4
4	Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways 2016 ·Cellular and Molecular Neurobiology ·Judith M. Silverman,(unknown),Leslie I. Grad,Andrew F. Hill,Bradley J. Turner,Justin J. Yerbury,Neil R. Cashman	79
5	TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion 2016 ·Scientific Reports ·Edward Pokrishevsky,Leslie I. Grad,Neil R. Cashman	63
6	Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS) 2016 ·Cold Spring Harbor Perspectives in Medicine ·Leslie I. Grad,Guy A. Rouleau,John Ravits,Neil R. Cashman	192
7	From molecule to molecule and cell to cell: Prion-like mechanisms in amyotrophic lateral sclerosis 2015 ·Neurobiology of Disease ·Leslie I. Grad,(unknown),Neil R. Cashman	61
8	Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding 2014 ·Prion ·Leslie I. Grad,Edward Pokrishevsky,Judith M. Silverman,Neil R. Cashman	45
9	Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms 2014 ·Proceedings of the National Academy of Sciences ·Leslie I. Grad,Justin J. Yerbury,Bradley J. Turner,William Guest,Edward Pokrishevsky,Megan A. O’Neill,Anat Yanai,Judith M. Silverman,Rafaa Zeineddine,Lisa Corcoran,Janet R. Kumita,Leila M. Luheshi,Masoud Yousefi,Bradley M. Coleman,Andrew F. Hill,Steven S. Plotkin,Ian R. Mackenzie,Neil R. Cashman	352
10	Prion-like activity of Cu/Zn superoxide dismutase 2014 ·Prion ·Leslie I. Grad,Neil R. Cashman	50
11	Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis 2012 ·PLoS ONE ·Edward Pokrishevsky,Leslie I. Grad,Masoud Yousefi,Jing Wang,Ian R. Mackenzie,Neil R. Cashman	141
12	Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit 2011 ·Journal of Toxicology and Environmental Health ·Will Guest,Judith M. Silverman,Edward Pokrishevsky,Megan A. O’Neill,Leslie I. Grad,Neil R. Cashman	54
13	Intermolecular transmission of superoxide dismutase 1 misfolding in living cells 2011 ·Proceedings of the National Academy of Sciences ·Leslie I. Grad,Will Guest,Anat Yanai,Edward Pokrishevsky,Megan A. O’Neill,Ebrima Gibbs,Valentyna Semenchenko,Masoud Yousefi,David S. Wishart,Steven S. Plotkin,Neil R. Cashman	218
14	Isolation and Functional Analysis of Mitochondria From the Nematode Caenorhabditis elegans 2007 ·Methods in molecular biology ·Leslie I. Grad,Leanne C. Sayles,Bernard D. Lemire	28
15	Riboflavin enhances the assembly of mitochondrial cytochrome c oxidase in C. elegans NADH-ubiquinone oxidoreductase mutants 2006 ·Biochimica et Biophysica Acta (BBA) - Bioenergetics ·Leslie I. Grad,Bernard D. Lemire	48
16	Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans 2005 ·Proceedings of the National Academy of Sciences ·Leslie I. Grad,Leanne C. Sayles,Bernard D. Lemire	35
17	Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis 2003 ·Human Molecular Genetics ·Leslie I. Grad	104
18	Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span 2001 ·Journal of Biological Chemistry ·William Y.W. Tsang,Leanne C. Sayles,Leslie I. Grad,David B. Pilgrim,Bernard D. Lemire	118
19	Locally released retinoic acid repatterns the first branchial arch cartilages in vivo 2000 ·Developmental Biology ·(unknown),(unknown),Leslie I. Grad,(unknown),Joy M. Richman	30
20	Inactivation of the Neurospora crassa mitochondrial outer membrane protein TOM70 by repeat-induced point mutation (RIP) causes defects in mitochondrial protein import and morphology 1999 ·Current Genetics ·Leslie I. Grad,(unknown),Walter Neupert,Roland Lill,Frank E. Nargang	24

About Leslie I. Grad

Leslie I. Grad is a scholar working on Aging, Neurology and Genetics, having authored 20 papers that have together received 1.9k indexed citations. Recurring topics across this work include Amyotrophic Lateral Sclerosis Research (12 papers), Mitochondrial Function and Pathology (7 papers) and Prion Diseases and Protein Misfolding (6 papers). The work is most often cited by research in Aging (197 citations), Neurology (908 citations) and Genetics (442 citations). Leslie I. Grad has collaborated with scholars based in Canada, Australia and Germany. Frequent co-authors include Neil R. Cashman, Edward Pokrishevsky, Bernard D. Lemire, Judith M. Silverman, Ian R. Mackenzie, Guy A. Rouleau, Megan A. O’Neill, John Ravits, Leanne C. Sayles and Masoud Yousefi. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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