Leon Frenken

4.0k citations

38 papers · 3.2k indexed · h-index 29

Radiology, Nuclear Medicine and Imaging top 0.5%
- Monoclonal and Polyclonal Antibodies Research 20
Biotechnology top 1%
- Transgenic Plants and Applications 8
Immunology top 5%
Molecular Biology top 5%
- Glycosylation and Glycoproteins Research 11
- Protein purification and stability 8
- Enzyme Catalysis and Immobilization 4
Endocrinology top 5%
Infectious Diseases
- Viral gastroenteritis research and epidemiology 5
Hematology
- Iron Metabolism and Disorders 3
Genetics
- Bacterial Genetics and Biotechnology 3

Co-authors: C. Theo Verrips Bernard de Geus Robin Ruuls Christian Cambillau Maarten R. Egmond Pim Hermans Michiel M. Harmsen J. Wil Bos
Cited by: Radiology, Nuclear Medicine and Imaging Biotechnology Immunology
Journals: Journal of Clinical Investigation (1 paper)Gastroenterology (1 paper)PLoS ONE (1 paper)
Partner nations: Netherlands France United Kingdom

In The Last Decade

Leon Frenken

37 papers receiving 3.1k citations

Peers

Countries citing papers authored by Leon Frenken

Since Specialization

Citations

This map shows the geographic impact of Leon Frenken's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leon Frenken with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leon Frenken more than expected).

Fields of papers citing papers by Leon Frenken

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leon Frenken. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leon Frenken. The network helps show where Leon Frenken may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Leon Frenken, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Leon Frenken Line = papers co-authored together Leon Frenken links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial American Journal of Clinical Nutrition ·Cornelius M. Smuts,Tonderayi M. Matsungo,Linda Malan,Herculina S. Kruger,Marinel Rothman,Jane Kvalsvig,Namukolo Covic,Karen Joosten,Saskia Osendarp,Maaike J. Bruins,Leon Frenken,Carl Lombard,Mieke Faber	2018	40
2	Inhibition of Iron Absorption by Calcium Is Modest in an Iron-Fortified, Casein- and Whey-Based Drink in Indian Children and Is Easily Compensated for by Addition of Ascorbic Acid Journal of Nutrition ·Thomas Walczyk,Sumithra Muthayya,Rita Wegmüller,Prashanth Thankachan,Aafje Sierksma,Leon Frenken,Tinku Thomas,Anura V. Kurpad,Richard F. Hurrell	2014	36
3	Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection Journal of Clinical Investigation ·Daisuke Tokuhara,Beatriz Álvarez,Mio Mejima,Tomoko Hiroiwa,Yuko Takahashi,Shiho Kurokawa,Masaharu Kuroda,Masaaki Oyama,Hiroko Kozuka‐Hata,Tomonori Nochi,Hiroshi Sagara,Farah Aladin,Harold Marcotte,Leon Frenken,Miren Iturriza‐Gómara,Hiroshi Kiyono,Lennart Hammarström,Yoshikazu Yuki	2013	67
4	Anti-Rotavirus Protein Reduces Stool Output in Infants With Diarrhea: A Randomized Placebo-Controlled Trial Gastroenterology ·Shafiqul Alam Sarker,Martin Jäkel,Shamima Sultana,Nur Alam,Pradip Kumar Bardhan,Mohammod Jobayer Chisti,Mohammed Abdus Salam,Winfried Theis,Lennart Hammarström,Leon Frenken	2013	54
5	In Vitro Neutralisation of Rotavirus Infection by Two Broadly Specific Recombinant Monovalent Llama-Derived Antibody Fragments PLoS ONE ·Farah Aladin,Alexandra W. C. Einerhand,Janneke Witte‐Bouma,Sandra Bezemer,Pim Hermans,Danielle Wolvers,Kate Bellamy,Leon Frenken,Jim Gray,Miren Iturriza‐Gómara	2012	28
6	Black tea reduces diarrhoea prevalence but decreases growth performance in enterotoxigenic Escherichia coli-infected post-weaning piglets Journal of Animal Physiology and Animal Nutrition ·Maaike J. Bruins,M. A. M. Vente-Spreeuwenberg,C. H. M. Smits,Leon Frenken	2010	18
7	Random serial sampling to evaluate efficacy of iron fortification: a randomized controlled trial of margarine fortification with ferric pyrophosphate or sodium iron edetate American Journal of Clinical Nutrition ·Maria Andersson,Winfried Theis,Michael Zimmermann,Jasmin Tajeri Foman,Martin Jäkel,Guus Duchateau,Leon Frenken,Richard F. Hurrell	2010	17
8	Lactobacilli Expressing Variable Domain of Llama Heavy‐Chain Antibody Fragments (Lactobodies) Confer Protection against Rotavirus‐Induced Diarrhea The Journal of Infectious Diseases ·Neha Pant,Anna Hultberg,Yaofeng Zhao,Lennart Svensson,Qiang Pan‐Hammarström,Kari Johansen,Peter H. Pouwels,Franco Maria Ruggeri,Pim Hermans,Leon Frenken,Thomas Borén,Harold Marcotte,Lennart Hammarström	2006	111
9	Therapeutic effect of llama derived VHH fragments against Streptococcus mutans on the development of dental caries Applied Microbiology and Biotechnology ·Carina Krüger,Anna Hultberg,Harold Marcotte,Pim Hermans,Sandra Bezemer,Leon Frenken,Lennart Hammarström	2006	26
10	Preventing Phage Lysis of Lactococcus Lactis in Cheese Production Using A Neutralizing Heavy-Chain Antibody Fragment from Llama Journal of Dairy Science ·A.M. Ledeboer,Sandra Bezemer,J.J.W. de Haard,I. M. Schäffers,C. Theo Verrips,Cees van Vliet,Eva‐Maria Düsterhöft,P. Zoon,Sylvain Moineau,Leon Frenken	2002	42
11	Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features Molecular Immunology ·Michiel M. Harmsen,Robin Ruuls,Isaäc J. Nijman,Théo Niewold,Leon Frenken,Bernard de Geus	2000	176
12	Improved production and function of llama heavy chain antibody fragments by molecular evolution Journal of Biotechnology ·Richard H.J van der Linden,Bernard de Geus,Leon Frenken,Hans Peters,C. Theo Verrips	2000	39
13	Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Richard H.J van der Linden,Leon Frenken,Bernard de Geus,Michiel M. Harmsen,Robin Ruuls,W Stok,L. de Ron,Stephen W. Wilson,Paul J. Davis,C. Theo Verrips	1999	365
14	The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation Immunogenetics ·Benjamin P Woolven,Leon Frenken,Paul van der Logt,P J Nicholls	1999	57
15	Recent advances in the large-scale production of antibody fragments using lower eukaryotic microorganisms Research in Immunology ·Leon Frenken,J. G. M. Hessing,Cees A. M. J. J. van den Hondel,C. Theo Verrips	1998	44
16	Factors affecting the fermentative production of a lysozyme-binding antibody fragment inEscherichia coli Biotechnology and Bioengineering ·Joseph S. Harrison,Eli Keshavarz‐Moore,P. Dunnill,Mark J. Berry,Arthur J. Fellinger,Leon Frenken	1997	24
17	Analysis of the structure of Pseudomonas glumae lipase Protein Engineering Design and Selection ·M.E.M. Noble,Anne Cleasby,L.N. Johnson,Maarten R. Egmond,Leon Frenken	1994	20
18	The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate FEBS Letters ·M.E.M. Noble,Anne Cleasby,L.N. Johnson,Maarten R. Egmond,Leon Frenken	1993	232
19	Pseudomonas glumae lipase: increased proteolytic stabifity by protein engineering Protein Engineering Design and Selection ·Leon Frenken,Maarten R. Egmond,A. M. Batenburg,C. Theo Verrips	1993	29
20	An accessory gene, lipB, required for the production of active Pseudomonas glumae lipase Molecular Microbiology ·Leon Frenken,J. Wil Bos,Chris J. Visser,Wally H. Müller,Jan Tommassen,C. Theo Verrips	1993	77

About Leon Frenken

Leon Frenken is a scholar working on Biotechnology, Radiology, Nuclear Medicine and Imaging and Immunology and Allergy, having authored 38 papers that have together received 3.2k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (20 papers), Glycosylation and Glycoproteins Research (11 papers), Protein purification and stability (8 papers), Transgenic Plants and Applications (8 papers), Viral gastroenteritis research and epidemiology (5 papers), Enzyme Catalysis and Immobilization (4 papers), Iron Metabolism and Disorders (3 papers) and Bacterial Genetics and Biotechnology (3 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (1.8k citations), Biotechnology (378 citations) and Immunology (678 citations). Leon Frenken has collaborated with scholars based in Netherlands, France and United Kingdom. Frequent co-authors include C. Theo Verrips, Bernard de Geus, Robin Ruuls, Christian Cambillau, Maarten R. Egmond, Pim Hermans, Michiel M. Harmsen, J. Wil Bos, Karel Heremans and Mireille Dumoulin. Their work appears in journals such as Journal of Clinical Investigation, Gastroenterology and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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